scholarly journals PHARMACOGNOSTIC STUDIES ON FLOWERS OF DREGEA VOLUBILIS: EVALUATION FOR AUTHENTICATION AND STANDARDIZATION

Author(s):  
BHASKAR DAS ◽  
ARNAB DE ◽  
PIU DAS ◽  
AMALESH NANDA ◽  
AMALESH SAMANTA

Objective: The various parts of Dregea volubilis (Family: Apocynaceae), locally known as Jukti (Bengali), are commonly used in Indian system of medicine to treat various ailments such as inflammation, piles, leukoderma, asthma, and tumors. Literature review suggested that there has been no detailed work on systemic pharmacognostic and phytochemical studies done on the flowers of the plant. The present study is aimed to lay down quality control parameters for D. volubilis flowers to confirm its identity, quality, and purity. Methods: The present work was designed to study detailed organoleptic, histological, quantitative standards, physicochemical, spectroscopic, and chromatographic characteristics of the flowers of D. volubilis. Results: The total ash, acid insoluble ash, water soluble ash, loss on drying, water, and alcohol soluble extractive values were found to be 11.767±0.130% (w/w), 1.287±0.106% (w/w), 9.140±0.344% (w/w), 14.110±0.061% (w/w), 21.600±0.133% (w/v), and 9.603±0.104% (w/v), respectively. Phytochemical screening of different extracts showed the presence of carbohydrates, proteins, amino acids, steroids, glycosides, alkaloids, flavonoids, tannins, and phenolics. The chromatographic study revealed the presence of rhamnose (103.229±4.994 μg/g), fructose (738.670±25.714 μg/g), glucose (285.532±24.465 μg/g), and maltose (49.082±5.206 μg/g). Conclusion: The characterization parameters of the present study may serve as a reference standard for proper authentication, identification and for distinguishing the plant from its adulterants.

2014 ◽  
Vol 15 (4) ◽  
Author(s):  
Camila Freitas de OLIVEIRA ◽  
Vinicius Bednarczuk OLIVEIRA ◽  
Fernanda Freitas OLIVEIRA ◽  
Obdulio Gomes MIGUEL ◽  
Marilis Dallarmi MIGUEL

As plantas medicinais são utilizadas por 80% da população de países em desenvolvimento, representando uma renda de 22 bilhões de dólares ao ano. As análises de umidade, cinzas e prospecção fitoquímica são essenciais para a caracterização das espécies vegetais auxiliando na identificação de espécies vegetais no processo de controle de qualidade. A espécie Psychotria fractistipula não apresenta uso popular, mas tem-se um grande interesse nas plantas do gênero Psychotria por apresentarem alcalóides alucinógenos em sua composição. O estudo farmacognóstico foi realizado devido a poucos estudos realizados com a espécie. As folhas de Psychotria fractistipula apresentaram umidade de 12,53% e os caules 9,43%, o teor de cinzas das folhas foi de 9,43% enquanto que nos caules foi de 4,06% segundo o estudo realizado. Na prospecção fitoquímica realizada em cromatografia de camada delgada a espécie apresentou em sua composição flavonoides, alcaloides, taninos, esteroides e triterpenos, os quais estão presentes em seu caule e folhas. 


2013 ◽  
Vol 14 (2) ◽  
Author(s):  
Fernanda Maria Marins Ocampos ◽  
Obdulio Gomes Miguel ◽  
Daniella Maria Soares de Oliveira

As plantas vêm sendo utilizadas pelas civilizações como alimento, medicamento e inclusive como agentes tóxicos. Os valores de umidade, cinzas totais e o resultado da prospecção fitoquímica são importantes para o controle de qualidade de medicamentos fitoterápicos, uma vez que são característicos das espécies vegetais, ou seja, podem ser utilizados para a caracterização da planta. Sapium glandulosum é também popularmente conhecida popularmente como leiteiro, pau de leite, burra leiteira, janaguba, seringarana, entre outras denominações. Tendo em vista os poucos estudos envolvendo a espécie, foram realizados testes para determinar os parâmetros farmacognósticos da planta. As folhas de Sapium glandulosum apresentaram uma umidade de 12,4%, enquanto que a casca da planta teve 13,4% umidade segundo o ensaio realizado. As folhas de Sapium glandulosum apresentaram 7,5% de cinzas, enquanto que a casca da planta teve 5,1% de cinzas segundo o ensaio realizado. Na prospecção fitoquímica foram encontrados flavonóides, iridóides, esteróides, taninos hidrolisáveis e condensados, aminogrupos, ácidos fixos, gomas e mucilagens nas Cascas e folhas. Cumarinas foram encontradas nas cascas.


Author(s):  
Almas Tarannum ◽  
Prathviraj Puranik ◽  
Suma V. Mallya

Ayurveda is the healing medicine. Dosha, Dhatu, Mala and Agni play important role in maintaining health of a person, but without equilibrium of Atma, Indriya and Manas they are helpless. Manas is one entity which is the controller of health. There are several herbs which have direct impact on Manas, among them Mandukaparni is one. Swarasa of Mandukaparni is highly effective, but it is not easily available for children. This study is intended to make Syrup form of Mandukaparni and evaluate its pharmacognostical parameters. According to the methodology refractive index, total solids, specific gravity, reducing and non Reducing sugar and HPTLC parameters were assessed. The results were found to be genuine fulfilling the standard protocol. This study is under taken to evaluate the pharmacognostic properties of Mandukaparni syrup.


Author(s):  
Komal D. Jani ◽  
Dharmendra P. Jani

Otomycosis denotes diffuse otitis externa due to fungal infections. The fungii are usually secondary invaders of the tissue rendered susceptible by bacterial infection, physical injury or excessive accumulation of cerumen in the external auditory canal. Karnasraava means discharge from ear which can be correlated with otorrhoea. Karnasraava (discharge) is one of symptom of otomycosis. Arka Taila has been mentioned in Shaarangadhara is very simple formula having ingredients i.e. Haridraa (Curcuma longa), Arka Patra Swarasa (Calotropis procera) and Sarshapa Taila (Brassica campetries). The quality control parameters resulted after scientific evaluation of Arka Taila can be used as reference standard for quality control or quality assurance of a pharmaceutical industry in order to have a proper quality check over its preparation and processing.


2001 ◽  
Vol 7 (2) ◽  
pp. 93-95
Author(s):  
P.C. Fuchs ◽  
A.L. Barry ◽  
S.D. Brown ◽  
M.M. Traczeski

2019 ◽  
Vol 1 (9) ◽  
Author(s):  
Anand Prakash ◽  
Pracheta Janmeda ◽  
Purnima Pathak ◽  
Sneha Bhatt ◽  
Vinay Sharma

2020 ◽  
Vol 136 ◽  
pp. 105231
Author(s):  
Luis Quintero-Fong ◽  
Francisco Ramírez ◽  
Gabriela Juárez ◽  
Yeudiel Gómez ◽  
Lucy Tirado ◽  
...  

1996 ◽  
Vol 40 (7) ◽  
pp. 1633-1639 ◽  
Author(s):  
P C Fuchs ◽  
A L Barry ◽  
S D Brown

More than 3,000 consecutive clinical bacterial isolates from 10 U.S. medical centers were subjected to standard broth microdilution and disk diffusion tests to determine their susceptibilities to levofloxacin, ofloxacin, D-ofloxacin, and ciprofloxacin. Levofloxacin was confirmed to be twice as active as ofloxacin and to have activity comparable to that of ciprofloxacin, with minor variations in activity against some species. The prevalence of resistant isolates was 7.1% to levofloxacin, 9.3% to ciprofloxacin, and 11.2% to ofloxacin. The susceptibilities of some species to the quinolones were less than those reported in previous studies. Pseudomonas aeruginosa isolates had the greatest variability in their susceptibilities to the three drugs between the participating centers. Two proposed zone size breakpoints for levofloxacin disk tests yielded similar low error rates. Ofloxacin and ciprofloxacin susceptibility test results correlated reasonably well with those of levofloxacin and could be used as surrogate indicators of levofloxacin susceptibility, but that resulted in some serious errors, and thus, direct testing of levofloxacin susceptibility is preferable. Replicate testing of standard quality control strains confirmed the established and proposed quality control parameters for all three quinolones tested.


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