scholarly journals ASSOCIATION BETWEEN NEUTROPHIL-TO-LYMPHOCYTE RATIO AND PLATELET-TO-LYMPHOCYTE RATIO WITH 1-YEAR MORTALITY IN HEMODIALYSIS PATIENT IN WANGAYA REGIONAL GENERAL HOSPITAL

2019 ◽  
pp. 50-52
Author(s):  
I PUTU YOGI SASTRAWAN ◽  
CHRISTINA PERMATA SHALIM
Keyword(s):  
Cohort Study ◽  
Relative Risk ◽  
General Hospital ◽  
Medical Records ◽  
Retrospective Cohort ◽  
Hemodialysis Patient ◽  
Neutrophil To Lymphocyte Ratio ◽  
Hospital Data ◽  
Platelet To Lymphocyte Ratio ◽  
Lymphocyte Ratio

Objective: The aim of this study was to determine whether neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) are associated with mortality risk in patients with hemodialysis (HD). Methods: We conducted a retrospective cohort study among regular HD patients at Wangaya Regional General Hospital. Data were collected from patients’ medical records in June 2018 and followed up until May 2019. Results: NLR and PLR were significantly associated with 1-year mortality (p=0.047 and p=0.009), with higher NLR (NLR>2.84) and higher PLR (PLR>10) associated with higher risk of 1-year mortality (relative risk [RR]=3.36 and RR=5.19). Conclusion: NLR and PLR were significantly associated with 1-year mortality in patients with HD.

scholarly journals Prognostic value of lymphocyte-to-monocyte ratio and neutrophil-to-lymphocyte ratio in follicular lymphoma: a retrospective cohort study

BMJ Open ◽  
2017 ◽  
Vol 7 (11) ◽  
pp. e017904 ◽  
Author(s):  
Shing Fung Lee ◽  
Miguel Angel Luque-Fernandez
Keyword(s):  
Cohort Study ◽  
Prognostic Factors ◽  
Follicular Lymphoma ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
International Prognostic Index ◽  
Prognostic Index ◽  
Neutrophil To Lymphocyte Ratio ◽  
Lymphocyte Ratio ◽  
Lymphocyte To Monocyte Ratio

ObjectivesThe clinical course and prognosis of follicular lymphoma (FL) are diverse and associated with the patient’s immune response. We investigated the lymphocyte-to-monocyte ratio (LMR) and neutrophil-to-lymphocyte ratio (NLR) as prognostic factors in patients with FL, including those receiving radiotherapy.DesignA retrospective cohort study.SettingRegional cancer centre in Hong Kong.Participants88 patients with histologically proven FL diagnosed between 2000 and 2014.Materials and methodsThe best LMR and NLR cut-off values were determined using cross-validated areas under the receiver operating characteristic curves. The extent to which progression-free survival (PFS) and overall survival differed by NLR and LMR cut-off values was assessed using Kaplan-Meier analysis and log-rank tests. A Cox proportional hazards model was fitted to adjust for confounders.ResultsThe best cut-off values for LMR and NLR were 3.20 and 2.18, respectively. The 5-year PFS was 73.6%. After multivariate adjustment, high LMR (>3.20) at diagnosis was associated with superior PFS, with a HR of 0.31 (95% CI 0.13 to 0.71), whereas high NLR at relapse was associated with poorer postprogression survival (HR 1.24, 95% CI 1.04 to 1.49).ConclusionsBaseline LMR and NLR at relapse were shown to be independent prognostic factors in FL. LMR and NLR are cheap and widely available biomarkers that could be used in combination with the Follicular Lymphoma International Prognostic Index by clinicians to better predict prognosis.

scholarly journals Platelet-to-Lymphocyte Ratio (PLR) Profile and Neutrophil-to-Lymphocyte Ratio (NLR) in Lung Cancer Patients in Ulin General Hospital Banjarmasin 2017-2018

2020 ◽  
Vol 16 (1) ◽  
pp. 25
Author(s):  
Haryati Haryati ◽  
Holly Diany
Keyword(s):  
Lung Cancer ◽  
Cancer Patients ◽  
General Hospital ◽  
Neutrophil To Lymphocyte Ratio ◽  
Advanced Stage ◽  
Platelet To Lymphocyte Ratio ◽  
Lung Cancer Patients ◽  
Lymphocyte Ratio ◽  
Anatomy Laboratory ◽  
End Stage

Abstract: Lung cancer is the leading cause of malignancy in the world reaching up to 13% of all cancer diagnoses. Platelet-to-Lymphocyte Ratio (PLR) and Neutrophil-to-Lymphocyte Ratio (NLR), are promising markers of inflammatory prognosis, clinical decisions for proper management of lung cancer patients. The research used a retrospective analytic observational study as its research method. Samples were taken from Pathology Anatomy Laboratory, and the medical record data of lung cancer patients in Ulin General Hospital Banjarmasin from 2017 to 2018. Male lung cancer patients have percentage of 72% with PLR NLR values by sex are not much different p>0.05. 23% of patients were aged ≥ 65 years and 77% were aged £ 65 years with value p>0.05. Adenocarcinoma reaches 65% with p>0.05. Most metastases are 44% pleural effusion with value p>0.05. Percentage of advanced stage is 90% with a higher PLR NLR value at the end stage. There is a meaningful relationship of NLR with lung cancer stage p<0.05, but no relantionship with PLR p>0.05. PRL and NRL are increased at advanced stage. NRL and PRL did not differ significantly based on age, sex and histology of lung cancer. Keywords: Platelet-to-lympho­cyte ratio (PLR), Neutrophil-to-lymphocyte ratio (NLR), lung cancer

scholarly journals Prognostic Role of Neutrophil to Lymphocyte Ratio and Platelet to Lymphocyte Ratio in the Survival of Patients with Esophageal Cancer

2021 ◽  
Author(s):  
Maryam Tajik ◽  
Mohammad Shirkhoda ◽  
Maryam Hadji ◽  
Monireh Sadat Seyyed- salehi ◽  
Elnaz Saeidi ◽  
...  
Keyword(s):  
Esophageal Cancer ◽  
Medical Records ◽  
Total Bilirubin ◽  
Laboratory Data ◽  
Neutrophil To Lymphocyte Ratio ◽  
Poor Survival ◽  
Platelet To Lymphocyte Ratio ◽  
Lymphocyte Ratio

Background: Different factors can affect the future of a person with cancer. The patient’s systemic inflammatory response is an important factor. Several inflammatory markers have been evaluated for measuring the patient’s response to cancer. We evaluated neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) as prognostic factors for survival in patients with pathologically proven esophageal cancer. Methods: In this retrospective cohort study, patients with pathologically approved esophageal cancer, who underwent surgical treatment in the cancer institute of Iran, were included. Demographic, pathological, and laboratory data of patients were obtained from the archive of medical records. Results: In this study, 135 patients with esophageal cancer with a mean age of 60 were studied. The median time of the follow-up period was 21 months. Mean NLR and PLR were 7.05 and 898, respectively. Patients’ survival had a significant relationship with their age, gender, tumor differentiation, receiving chemotherapy, absolute neutrophil count, total bilirubin, direct bilirubin, and NLR. Conclusion: According to the results, in a multivariable investigation, it was demonstrated that a high NLR has a direct effect on patients’ poor survival.

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