scholarly journals CORRELATION OF SERUM OSTEOCALCIN LEVEL AND PERIODONTAL ATTACHMENT LOSS WITH OSTEOPOROSIS RISK STATUS IN POSTMENOPAUSAL WOMEN

2018 ◽  
Vol 9 ◽  
pp. 92
Author(s):  
Dimas Ilham Hutomo ◽  
Sri Lelyati C Masulili ◽  
Fatimah Maria Tadjoedin ◽  
Lindawati S Kusdhany

Objective: To assess the relationship between serum osteocalcin and periodontal clinical attachment loss (CAL) in postmenopausal women in relation to their osteoporosis risk status.Methods: A cross-sectional study was carried out on 71 postmenopausal women in Kenari District, Central Jakarta, Indonesia. The periodontal examination for all the subjects included a CAL measurement. The serum osteocalcin level was analyzed using ELISA.Results: The correlation between the serum osteocalcin level in patients with CAL and the risk of osteoporosis was analyzed with the Spearman test. The normal group had 29 subjects (40.84%), the osteopenic group had 23 subjects (32.39%), and the osteoporotic group had 19 subjects (26.76%). There was a significant correlation between CAL and the osteoporosis high-risk status (p<0.05) and no significant correlation between the serum osteocalcin level and the osteoporosis status (p>0.05).Conclusion: No correlation was found between CAL and the serum osteocalcin level (p>0.05).

Circulation ◽  
2014 ◽  
Vol 129 (suppl_1) ◽  
Author(s):  
Ju-Mi Lee ◽  
Hansol Choi ◽  
Kyung Min Kim ◽  
YooSik Youm ◽  
Yumie Rhee ◽  
...  

Importance: Association between sleep duration and health related outcome studies have been published consistently. However there have been few studies of the association between sleep duration and bone formation in elderly. Objective: The aim of this study is to examine association between sleep duration and serum osteocalcin level in an elderly Korean population. Design: Cross sectional analysis using baseline cohort data. Setting: Community based setting Participants: Among the total of 927 participants, we excluded 1 participant because of the absence on sleep duration answer. A final total of 926 participants (624 women and 302 men aged 64-87 years) who completed baseline health examination in 2012 were enrolled in this study. Measurement: Sleep duration was measured by interviewer-assisted questionnaire. Participants answered their regular time of going to bed, time of opening eyes in the morning, and time of regular nap using open questions during the passing year. Serum osteocalcin level, a known biomarker of osteogenesis, was measured by electrochemiluminescence immunoassay method in the central research laboratory. The association between sleep duration (minutes/day) and serum osteoclacin level (ng/ml) was assessed by multiple linear regression analysis. Results: In the total population, sleep duration had significant association with serum osteocalcin level (ß=-0.008, p=0.013). One hour increase in sleep duration was associated with 0.48 ng/ml increase in serum osteocalcin level. This association remained after controlling for age, sex, body mass index, cigarette smoking, alcohol drinking, physical activity, and serum 25(OH) vitamin D (ß=0.012, p<0.001). This association was consistent before and after adjusting confounders in women (ß=-0.010, p=0.019, ß=-0.011, p=0.009, respectively) and men (ß=-0.013, p=0.012, ß=-0.013, p=0.011, respectively). Conclusions: Our findings suggest that longer sleep duration is associated with higher bone formation process in an elderly of Korean.


2011 ◽  
Vol 28 (6) ◽  
pp. 472-477 ◽  
Author(s):  
Suk Woo Lee ◽  
Hyun Hee Jo ◽  
Mee Ran Kim ◽  
Young Oak You ◽  
Jang Heub Kim

2015 ◽  
Vol 83 (3) ◽  
pp. 429-434 ◽  
Author(s):  
Yuqi Luo ◽  
Xiaojing Ma ◽  
Yaping Hao ◽  
Yiting Xu ◽  
Qin Xiong ◽  
...  

Author(s):  
Shreeya Aryal ◽  
Ameena Pradhan ◽  
Shilu Shrestha ◽  
Surendra Man Shrestha

Introduction: Obesity is regarded as unnecessary body fat in ratio to lean body mass. Besides being an established risk factor for cardiovascular and other systemic diseases, obesity has been suggested to be a potential threat for periodontitis as well. Objective: The objective of the study was to learn relationship between body mass index (BMI) and periodontal disease. Methods: This analytical cross-sectional study was conducted at People’s Dental College from February 16 to April 15, 2021 after ethical approval. Seventy-two participants were selected conveniently who, on the basis of calculation of weight and height were allocated into two groups: Group A: participants with normal BMI, Group B: Obese/ overweight individuals. Plaque index, gingival index, periodontal pocket, and clinical attachment loss were recorded in both the groups to assess the periodontal disease status. On basis of findings, the two groups were statistically compared. Results: The result showed clinical attachment loss was significantly higher (P <0.001) in overweight/obese group than in normal BMI group (P =0 .001). Conclusion: The findings of this study suggest that obesity and overweight can be a possible predisposing factor for periodontal disease.


Renal Failure ◽  
2014 ◽  
Vol 36 (10) ◽  
pp. 1481-1485 ◽  
Author(s):  
Hilmi Umut Unal ◽  
Murat Çelik ◽  
Yalçın Gökoğlan ◽  
Hakkı Çetinkaya ◽  
Mahmut Gök ◽  
...  

1990 ◽  
Vol 11 ◽  
pp. S59
Author(s):  
F. Szalay ◽  
P. Lakatos ◽  
J. Németh ◽  
M. Abonyi ◽  
B. Büki ◽  
...  

2017 ◽  
Vol 96 (3) ◽  
pp. 261-269 ◽  
Author(s):  
D.C. Penoni ◽  
T.K.S. Fidalgo ◽  
S.R. Torres ◽  
V.M. Varela ◽  
D. Masterson ◽  
...  

Osteoporosis is a systemic skeletal disease characterized by low bone mineral density (BMD) and has been considered a risk factor for periodontal disease. The aim of this systematic review and meta-analysis was to verify the scientific evidence for the association of periodontal attachment loss with low BMD in postmenopausal women. A systematic search of the literature was performed in databases until August 2016, in accordance with Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) guidelines. Eligibility criteria included studies that compared clinical attachment loss (CAL) between postmenopausal women with low and normal BMD. Studies using similar methodology, with lower and higher risk of bias, were pooled into 3 different meta-analyses to compare CAL among women with normal BMD, osteoporosis, and osteopenia. In the first meta-analysis, mean CAL was compared among groups. In the other 2 meta-analyses, the mean percentages of sites with CAL ≥4 mm and ≥6 mm were respectively compared among groups. From 792 unique citations, 26 articles were selected for the qualitative synthesis. Eleven of the studies were appraised as presenting low risk of bias, and the association between low BMD and CAL was observed in 10 of these studies. Thirteen cross-sectional articles were included in the meta-analysis for osteoporosis and 9 in the osteopenia analysis. Women with low BMD presented greater mean CAL than those with normal BMD (osteoporosis = 0.34 mm [95% confidence interval (CI), 0.20–0.49], P < 0.001; osteopenia = 0.07 mm [95% CI, 0.01–0.13], P = 0.02). Only studies with lower risk of bias were available for the analysis of CAL severity. Women with low BMD presented more severe attachment loss, represented as mean percentage of sites with CAL ≥4 mm (osteoporosis = 3.04 [95% CI, 1.23–4.85], P = 0.001; osteopenia = 1.74 [95% CI, 0.36–3.12], P = 0.01) and CAL ≥6 mm (osteoporosis = 5.07 [95% CI, 2.74–7.40], P < 0.001). This systematic review and meta-analysis indicates that postmenopausal women with osteoporosis or osteopenia may exhibit greater CAL compared with women with normal BMD.


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