scholarly journals Efficacy of Whole-Body versus Lesional Application of Permethrin Cream for Scabies Treatment: A Quasi-Experimental Study

2021 ◽  
Vol 11 (2) ◽  
pp. 68-71
Author(s):  
Saleha Sungkar ◽  
Rose A. Haswinzky ◽  
Yasmine A. Dwinastiti ◽  
Aji W. Wardhana ◽  
Fanny P. Irmawati ◽  
...  
Keyword(s):  
Experimental Study ◽  
Controlled Trial ◽  
Cost Effective ◽  
Boarding Schools ◽  
Whole Body ◽  
Cure Rate ◽  
Randomized Controlled ◽  
Quasi Experimental ◽  
Keywords Scabies ◽  
Larger Sample

Objective: The study aims to evaluate the efficacy of whole-body versus lesional application of 5% permethrin cream for scabies eradication. Design: This quasi-experimental study was conducted on September-October 2018 at boarding schools in Bogor and East Jakarta, Indonesia. Subjects were randomized into two groups, 51 students each. Interventions: The first group received a whole-body application while the second group received lesional application of 5% permethrin cream. Evaluation was performed after 7 and 28 days. Main outcome measures: Proportion of lesions cured following the intervention Results: The prevalence of scabies was 41% and 33% at the boarding schools in Bogor and East Jakarta, respectively. Subjects from both groups had similar lesion distributions at baseline (p>0.05). Following intervention, the number of lesions reduced significantly (p<0.001) and both treatments were equally effective in treating scabies with 84.6% vs 91.5% cure rate [Relative Risk (RR) 1.8(0.6-5.0); p>0.05]. Conclusion: Lesional application of 5% permethrin is proven to be equally effective in treating scabies with higher cure rate. This method shows advantage for scabies treatment. In addition to reduce the unwanted side effects, it is more cost-effective and convenient. Further studies with larger sample size and randomized controlled trial design are warranted. Keywords: scabies, permethrin, whole-body application, lesional application, cure rate

scholarly journals Effect of leg wrapping technique on prevention of spinal induced hypotension and fetal acidosis during cesarean section: Randomized controlled trial

2019 ◽  
Vol 10 (2) ◽  
pp. 70
Author(s):  
Samah Nasser Abd El-Aziz El-Shora ◽  
Amina Mohamed Rashad El-Nemer
Keyword(s):  
Randomized Controlled Trial ◽  
Cesarean Section ◽  
Controlled Trial ◽  
Intervention Group ◽  
Cost Effective ◽  
Control Group ◽  
Induced Hypotension ◽  
Randomized Controlled ◽  
Significant Difference ◽  
Wrapping Technique

Background and aim: Hypotension during cesarean section (CS) under spinal anesthesia has been a subject of scientific study for more than 50 years and the search for the most effective strategy to achieve hemodynamic stability remains challenging. Aim: The study was carried out to apply leg wrapping technique for the prevention of spinal-induced hypotension (SIH) during CS.Methods: Randomized Controlled Trial design was utilized at cesarean delivery operating room Mansoura General Hospital in El-Mansoura City during the period from May 2018 to November 2018. A purposive sample of 88 pregnant women, assigned randomly to an intervention group (n = 44) in which their legs wrapped with elastic crepe bandage and control group (n = 44) in which no wrapping was done. Data collected for maternal, neonatal hemodynamic and signs of hypotension, the feasibility of application and cost analysis.Results: There was a statistically significant difference in the incidence of SIH and Ephedrine use among both groups (18.20% in leg wrapping group whereas 75% in control group). In addition, neonatal acidosis and NICU admission were less among leg wrapping group (11.40%, 9.10% respectively). Economically, leg wrapping technique was cost effective compared to the cost of the hospital regimen for treating SIH and admission to (NICU).Conclusion and recommendations: Leg wrapping technique was cost effective and an efficient method for decreasing SIH, neonatal acidosis and Ephedrine administration. It is recommended to apply leg wrapping technique in maternal hospitals' protocol of care for decreasing SIH during CS.

scholarly journals Is it cost effective to use a 2% chlorhexidine wipes bath to reduce central-line associated blood stream infection? A quasi-experimental study

2021 ◽  
Vol 25 (1) ◽  
pp. 101538
Author(s):  
Diego Feriani ◽  
Ercilia Evangelista Souza ◽  
Larissa Gordilho Mutti Carvalho ◽  
Aline Santos Ibanes ◽  
Eliana Vasconcelos ◽  
...  
Keyword(s):  
Experimental Study ◽  
Blood Stream Infection ◽  
Cost Effective ◽  
Blood Stream ◽  
Central Line ◽  
Quasi Experimental

scholarly journals Whole body vibration exercise for chronic low back pain: study protocol for a single-blind randomized controlled trial

Trials ◽  
2014 ◽  
Vol 15 (1) ◽  
pp. 104 ◽  
Author(s):  
Xue-Qiang Wang ◽  
Yan-Lin Pi ◽  
Pei-Jie Chen ◽  
Bin-Lin Chen ◽  
Lei-Chao Liang ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Low Back Pain ◽  
Back Pain ◽  
Controlled Trial ◽  
Whole Body Vibration ◽  
Whole Body ◽  
Low Back ◽  
Vibration Exercise ◽  
Randomized Controlled ◽  
Single Blind

scholarly journals SCIPA Full-On: A Randomized Controlled Trial Comparing Intensive Whole-Body Exercise and Upper Body Exercise After Spinal Cord Injury

2018 ◽  
Vol 32 (6-7) ◽  
pp. 557-567 ◽  
Author(s):  
Mary P. Galea ◽  
Sarah A. Dunlop ◽  
Timothy Geraghty ◽  
Glen M. Davis ◽  
Andrew Nunn ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Randomized Controlled Trial ◽  
Adverse Events ◽  
Controlled Trial ◽  
Upper Body ◽  
Whole Body ◽  
Upper Body Exercise ◽  
Randomized Controlled ◽  
Cord Injury ◽  
Full Body

Background. While upper body training has been effective for improving aerobic fitness and muscle strength after spinal cord injury (SCI), activity-based therapies intended to activate the paralyzed extremities have been reported to promote neurological improvement. Objective. To compare the effectiveness of intensive whole-body exercise compared with upper body exercise for people with chronic SCI. Methods. A parallel-group randomized controlled trial was conducted. Participants with a range of SCI levels and severity were randomized to either full-body exercise (FBE) or upper body exercise (UBE) groups (3 sessions per week over 12 weeks). FBE participants underwent locomotor training, functional electrical stimulation-assisted leg cycling, and trunk and lower extremity exercises, while UBE participants undertook upper body strength and aerobic fitness training only. The primary outcome measure was the American Spinal Injury Association (ASIA) motor score for upper and lower extremities. Adverse events were systematically recorded. Results. A total of 116 participants were enrolled and included in the primary analysis. The adjusted mean between-group difference was −0.04 (95% CI −1.12 to 1.04) for upper extremity motor scores, and 0.90 (95% CI −0.48 to 2.27) for lower extremity motor scores. There were 15 serious adverse events in UBE and 16 in FBE, but only one of these was definitely related to the experimental intervention (bilateral femoral condyle and tibial plateau subchondral fractures). No significant between-group difference was found for adverse events, or functional or behavioral variables. Conclusions. Full-body training did not lead to improved ASIA motor scores compared with upper body training in people with chronic SCI.

scholarly journals The ESCAPS study: a feasibility randomized controlled trial of early electrical stimulation to the wrist extensors and flexors to prevent post-stroke complications of pain and contractures in the paretic arm

2019 ◽  
Vol 33 (12) ◽  
pp. 1919-1930
Author(s):  
Joanna C Fletcher-Smith ◽  
Dawn-Marie Walker ◽  
Kate Allatt ◽  
Nikola Sprigg ◽  
Marilyn James ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Electrical Stimulation ◽  
Data Collection ◽  
Usual Care ◽  
Controlled Trial ◽  
Cost Effective ◽  
Outcome Data ◽  
Attrition Rates ◽  
Post Stroke ◽  
Randomized Controlled

Objective: To establish feasibility of initiating electrical stimulation treatment of wrist extensors and flexors in patients early after stroke to prevent muscle contractures and pain. Design: Feasibility randomized controlled trial with economic evaluation. Setting: A specialist stroke unit in Nottinghamshire. Subjects: A total of 40 patients recruited within 72 hours post-stroke with arm hemiparesis. Interventions: Participants were randomized to receive usual care or usual care and electrical stimulation to wrist flexors and extensors for 30 minutes, twice a day, five days a week for three months. Initial treatment was delivered by an occupational therapist or physiotherapist who trained participants to self-manage subsequent treatments. Measures: Measures of feasibility included recruitment and attrition rates, completion of treatment, and successful data collection. Outcome data on wrist range of motion, pain, arm function, independence, quality of life, and resource use were measured at 3-, 6-, and 12-months post-randomization. Results: A total of 40 participants (of 215 potentially eligible) were recruited in 15 months (20 men; mean age: 72 (SD: 13.0)). Half the participants lacked mental capacity and were recruited by consultee consent. Attrition at three-month follow-up was 12.5% (death ( n = 2), end-of-life care ( n = 2), and unable to contact ( n = 1)). Compliance varied (mean: 65 (SD: 53)) and ranged from 10 to 166 treatments per patient (target dosage was 120). Data for a valid economic analysis can be adequately collected. Conclusion: Early initiation of electrical stimulation was acceptable and feasible. Data collection methods used were feasible and acceptable to participants. A large definitive study is needed to determine if electrical stimulation is efficacious and cost effective.

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