scholarly journals Diagnostics of cerebral venous thrombosis associated with COVID-19 in young adults: clinical characteristics and imaging patterns

2021 ◽  
Vol 12 (3) ◽  
pp. 43-53
Author(s):  
F. Z. Olimova ◽  
Ye. G. Klocheva ◽  
V. N. Semich ◽  
V. V. Goldobin ◽  
S. V. Lobzin ◽  
...  
Keyword(s):  
Young Adults ◽  
Venous Thrombosis ◽  
Cerebral Venous Thrombosis ◽  
Clinical Laboratory ◽  
Brain Mri ◽  
Intravenous Contrast ◽  
Cerebrovascular Complications ◽  
Contrast Magnetic Resonance ◽  
Venous Infarcts ◽  
Initiation Of Therapy

Introduction. Cerebral venous thrombosis (CVT) is relatively rare, but leads to the development of cerebral venous infarction, intracranial hemorrhage, followed by severe disability and death. Due to the epidemiological situation caused by COVID-19, the incidence of CVT is increasing.Aims and objectives: to analyze clinical, laboratory instrumental and neuroimaging (multislice computed tomography (MSCT), MSCT — with intravenous contrast, magnetic resonance imaging of the brain (MRI) and MRI venography) data that confirmed the development of CVT in patients with COVID-19.Methods. Data of 5 young adults with cerebral venous thrombosis (CVT) associated with COVID-19 are presented.Results. Аmong 5 reported cases of COVID-19, two patients presented with venous infarcts (hemorrhagic and ischemic), 3 patients developed encephalopathy syndrome without acute cerebral infarction.Conclusion. Possibilities of modern imaging technologies permitted to timely diagnosis cerebral venous thrombosis associated with COVID-19, that can lead to immediate initiation of therapy and to prevent the development of cerebrovascular complications during the COVID-19 pandemic.

scholarly journals Cerebral Venous Thrombosis: A Mimic of Brain Metastases in Colorectal Cancer Associated with a Better Prognosis

2013 ◽  
Vol 2013 ◽  
pp. 1-3 ◽  
Author(s):  
Nida Iqbal ◽  
Atul Sharma
Keyword(s):  
Brain Metastases ◽  
Venous Thrombosis ◽  
Cerebral Venous Thrombosis ◽  
Brain Mri ◽  
Colon Adenocarcinoma ◽  
Rapid Diagnosis ◽  
Favourable Outcome ◽  
Neurological Dysfunction ◽  
Low Molecular Weight ◽  
Initiation Of Therapy

Malignancy is known to be one of the predisposing factors of cerebral venous thrombosis (CVT) due to its hypercoagulable state. CVT is a rare disorder which can lead to frequent misdiagnoses of brain metastases in such cases. We report here the case of a 35-year-old female with metastatic colon adenocarcinoma presenting with sudden neurological symptoms. Brain MRI and magnetic resonance venography confirmed the presence of CVT. She was treated with low molecular weight heparin followed by warfarin. She recovered and is doing well on warfarin after 5 months of diagnosis of CVT. CVT should be strongly suspected as a cause of neurological dysfunction in any case of disseminated malignancy including colon adenocarcinoma. Rapid diagnosis and initiation of therapy should be considered because of its favourable outcome.

scholarly journals Cerebral Venous Thrombosis: What's New?

2021 ◽  
Vol 41 (01) ◽  
pp. 025-030
Author(s):  
Diana Aguiar de Sousa
Keyword(s):  
Young Adults ◽  
Venous Thrombosis ◽  
Cerebral Venous Thrombosis ◽  
Cerebral Veins ◽  
Cerebrovascular Disorder ◽  
Recent Advances ◽  
Children And Young Adults

AbstractThrombosis of the cerebral veins and sinuses (CVT) is a distinct cerebrovascular disorder that, unlike arterial stroke, most often affects children and young adults, especially women. In this review, we will summarize recent advances on the knowledge of patients with CVT.

scholarly journals Risk factors and diagnosis of cerebral venous thrombosis: Data from a cohort of 45 Romanian patients

2014 ◽  
Vol 60 (5) ◽  
pp. 207-214
Author(s):  
Rodica Bălaşa ◽  
M Daboczi ◽  
Oana Costache ◽  
Smaranda Maier ◽  
Z Bajko ◽  
...  
Keyword(s):  
Risk Factors ◽  
Venous Thrombosis ◽  
Brain Imaging ◽  
Cerebral Venous Thrombosis ◽  
Sinus Thrombosis ◽  
Demographic Data ◽  
Brain Mri ◽  
Clinical Aspects ◽  
Initial Symptom ◽  
Clinical Criteria

Abstract Cerebral venous thrombosis (CVT) represents 1% of the total stroke pathology but is a real challenge both regarding the diagnosis and the treatment. Objective: Evaluate different etiological, demographical, clinical, imaging and therapeutic aspects of CVT. Material: Prospective study during 4 years. From the total 3658 patients hospitalized with acute stroke, 45 (1.23%) had CVT. For each patient, were recorded: demographic data, symptom of onset, type of onset, daily habits, medical history, neurological examination, brain imaging (CT and MRI with venography). Statistical analysis: data are presented as mean and SD and Student t test was applied. Results: Mean age was 44.07± 23,12 years; female: male ratio 2.21:1. The most frequent type of onset was acute (77.78%). Headache was found in 80% of cases as initial symptom, followed by neurological focal deficits. As risk factors, thrombophilia was found most often (59.5%), followed by local infections. No risk factors were found in 17.8% of cases. The brain imaging was positive in 29 patients. In 16 cases, the imaging workout was negative and the diagnosis consisted of clinical criteria, risk factors, response to heparin treatment. Conclusions: CVT is a rare pathology that affects mainly young women and that needs a complex diagnostic evaluation. The patient prototype diagnosed with CVT in our region: female of 44 years old, with an intense acute headache, with MRI showing direct signs of transverse sinus thrombosis, with a thrombophilic state and good response to anticoagulants. Brain MRI is the imaging investigation required but clinical aspects play a decisive role.

scholarly journals Cerebral Venous Thrombosis in a Patient with Immune Thrombocytopenia, an Apparent Paradox

2020 ◽  
Vol 13 (2) ◽  
pp. 588-594 ◽  
Author(s):  
Maimoonah A. Rasheed ◽  
Arwa E. Alsaud ◽  
Sania Razzaq ◽  
Afraa Fadul ◽  
Mohamed A. Yassin
Keyword(s):  
Venous Thrombosis ◽  
Cerebral Venous Thrombosis ◽  
Immune Thrombocytopenia ◽  
Intravenous Immunoglobulins ◽  
Apparent Paradox ◽  
Multiple Line ◽  
Thrombopoietin Receptor ◽  
Thrombopoietin Receptor Agonist ◽  
Venous Infarcts ◽  
Low Platelet Count

We present a paradoxical case of immune thrombocytopenia (ITP) that presented with cerebral venous thrombosis. A 39-year-old female patient diagnosed with chronic ITP, who failed treatment on multiple-line agents, was started on eltrombopag (thrombopoietin receptor agonist), which she was not compliant to. The patient later developed extensive cerebral venous thrombosis, along with venous infarcts, and intracranial and subarachnoid hemorrhage. She was treated with intravenous immunoglobulins as well as steroid therapy and was simultaneously started on anticoagulation. The patient improved clinically and radiologically. This case is among few reported cases which signify that patients with ITP are inherently prone to thrombosis despite low platelet count and treating these patients can be a dilemma. Judicious use of anticoagulation and immunosuppressive therapy is recommended based on available evidence pending further recommendations and guidelines about treatment of thrombosis in ITP.

Cerebral venous thrombosis in young adults: 2 Case reports

2001 ◽  
Vol 82 (5) ◽  
pp. 683-688 ◽  
Author(s):  
Ann Francine Dzialo ◽  
Randie M. Black-Schaffer
Keyword(s):  
Young Adults ◽  
Venous Thrombosis ◽  
Cerebral Venous Thrombosis ◽  
Case Reports

scholarly journals Unusual Case of Cerebral Venous Thrombosis in Patient with Crohn's Disease

2015 ◽  
Vol 7 (2) ◽  
pp. 115-120 ◽  
Author(s):  
Inha Kim ◽  
Kyung-Hyun Min ◽  
Minju Yeo ◽  
Ji Seon Kim ◽  
Sung Hyun Lee ◽  
...  
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Venous Thrombosis ◽  
Disease Activity ◽  
Cerebral Venous Thrombosis ◽  
Brain Mri ◽  
Active Phase ◽  
Filling Defect ◽  
Sudden Onset ◽  
Acute Infarction

The development of cerebral venous thrombosis (CVT) as a secondary complication of Crohn's disease (CD) seems to be rare, but it is generally accepted that the disease activity of CD contributes to the establishment of a hypercoagulable state. Here, we describe a case of CVT that developed outside the active phase of CD. A 17-year-old male visited the emergency room because of a sudden onset of right-sided weakness and right-sided hypesthesia. He had been diagnosed with CD 1 year before and was on a maintenance regimen of mesalazine and azathioprine. He did not exhibit any symptoms indicating a CD flare-up (bloody stools, abdominal pain, complications, or weight loss). A brain MRI scan revealed an acute infarction of the left frontal cortex and a cortical subarachnoid hemorrhage. Additionally, a magnetic resonance venography revealed a segmental filling defect in the superior sagittal sinus and also the non-visualizability of some bilateral cortical veins. The characteristics of the present case suggest that the risk of CVT is most likely related to CD per se rather than disease activity associated with CD.

La risonanza magnetica nello studio delle trombosi venose cerebrali

1989 ◽  
Vol 2 (2) ◽  
pp. 125-134 ◽  
Author(s):  
C.F. Andreula ◽  
R. Paladini ◽  
A. Carella
Keyword(s):  
Contrast Media ◽  
Venous Thrombosis ◽  
Cerebral Venous Thrombosis ◽  
Risonanza Magnetica ◽  
Diagnostic Problem ◽  
Hyperintense Signal ◽  
Venous Infarcts ◽  
Nello Studio ◽  
T2 Weighted Images

Gli autori propongono la risonanza magnetica come esame di prima scelta nello studio delle trombosi venose cerebrali. La presenza di un segnale iperintenso nelle immagini pesate in T1 e T2, lungo il decorso delle vene cerebrali, conferma senza dubbio la diagnosi. Vengono discussi i problemi relativi all'effetto paradosso del flusso ematico cerebrale ed i protocolli d'indagine di questa patologia. The use of MR without any dependance on field strenght can solve the diagnostic problem of cerebral venous thrombosis, avoiding contrast media and/or vessel puncture. In fact the easy detection of hyperintense signal within venous structures, revealed in T1 weighted images and persistent in T2 weighted images, confirm the clinical hyphothesis of cerebral venous thrombosis, without any further examinations. The higher sensibility of MR will show venous infarcts and haemorragic soffusions, sometimes maldetected by CT.

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