Anticancer properties of andrographis paniculata nees Leaf extract on human larynx carcinoma

2017 ◽  
Vol 8 (2) ◽  
Author(s):  
Dr. K. PADMALO CHANA
Keyword(s):  
Leaf Extract ◽  
Andrographis Paniculata ◽  
Larynx Carcinoma ◽  
Anticancer Properties ◽  
Human Larynx ◽  
Human Larynx Carcinoma

scholarly journals Bioorthogonal metabolic glycoengineering of human larynx carcinoma (HEp-2) cells targeting sialic acid

2010 ◽  
Vol 6 ◽  
Author(s):  
Arne Homann ◽  
Riaz-ul Qamar ◽  
Sevnur Serim ◽  
Petra Dersch ◽  
Jürgen Seibel
Keyword(s):  
Sialic Acid ◽  
Cell Surface ◽  
Carcinoma Cell ◽  
Larynx Carcinoma ◽  
Interaction Processes ◽  
Acid Analogue ◽  
Human Larynx ◽  
Sialic Acid Analogue ◽  
Metabolic Glycoengineering ◽  
Human Larynx Carcinoma

Sialic acids are located at the termini of mammalian cell-surface glycostructures, which participate in essential interaction processes including adhesion of pathogens prior to infection and immunogenicity. Here we present the synthesis and bioorthogonal metabolic incorporation of the sialic acid analogue N-(1-oxohex-5-ynyl)neuraminic acid (Neu5Hex) into the cell-surface glycocalyx of a human larynx carcinoma cell line (HEp-2) and its fluorescence labelling by click chemistry.

scholarly journals Evaluation of Transfected HEP-2 Cell Line Using ß-Galactosidase Reporter Assay System

2011 ◽  
Vol 8 (3) ◽  
pp. 728-735
Author(s):  
Baghdad Science Journal
Keyword(s):  
Cell Line ◽  
High Efficiency ◽  
Carcinoma Cell ◽  
Transfection Efficiency ◽  
Carcinoma Cell Line ◽  
Larynx Carcinoma ◽  
Human Larynx ◽  
Therapy Studies ◽  
Human Larynx Carcinoma ◽  
Transfection Agent

Liposome-mediated transfection of cancer cells provide a valuable experimental technique to study cellular gene expression and may also be adapted for gene therapy studies. However, the widely recognized advantage of liposome-mediated transfection is high efficiency. Therefore, this study were performed to optimize transfection techniques in human larynx carcinoma cell line Hep-2 using the commercial synthetic lipid TransFast™ Reagent and monitoring the expression efficiency by using the pSV-?-galactosidase Control Vector which encoded ?-galactosidase, maximum transfection efficiency were achieved with TransFast™ Reagent used at the Charge ratios of 2:1 and 0.5 µg DNA/ml, this is indicate that TransFast™ Reagent can be used as an efficient transfection agent to deliver foreign DNA into human larynx carcinoma cell line Hep-2 and expression of the transgene efficiently.

Hyperthermic modulation of resistance tocis-diammine-dichloroplatinum(II) in human larynx carcinoma cells

1997 ◽  
Vol 13 (2) ◽  
pp. 205-214 ◽  
Author(s):  
L. Beketić-Oreŝ Ković ◽  
M. Jakŝić ◽  
S. Oreŝković ◽  
M. Osmak
Keyword(s):  
Carcinoma Cells ◽  
Larynx Carcinoma ◽  
Human Larynx ◽  
Human Larynx Carcinoma

Characterization of human larynx carcinoma cell lines HLaC′79 and HLaC′82: a common origin but diverged malignancies

1995 ◽  
Vol 13 (5) ◽  
pp. 319-327 ◽  
Author(s):  
Anna M. Tomson ◽  
Janny Scholma ◽  
Trijnie Dijkhuizen ◽  
André P. M. Wijnakker ◽  
Miriam van der Werf ◽  
...  
Keyword(s):  
Cell Lines ◽  
Carcinoma Cell ◽  
Common Origin ◽  
Larynx Carcinoma ◽  
Carcinoma Cell Lines ◽  
Human Larynx ◽  
Human Larynx Carcinoma

Small Heat Shock Protein hsp27 as a Possible Mediator of Intercellular Adhesion-Induced Drug Resistance in Human Larynx Carcinoma HEp-2 Cells

2003 ◽  
Vol 23 (4) ◽  
pp. 187-197 ◽  
Author(s):  
Vladimir V. Mazurov ◽  
Marina E. Solovieva ◽  
Violetta V. Leshchenko ◽  
Alexey G. Kruglov ◽  
Eveline F. Edelweiss ◽  
...  
Keyword(s):  
Hydrogen Peroxide ◽  
Heat Shock ◽  
Heat Shock Protein ◽  
Small Heat Shock Protein ◽  
Larynx Carcinoma ◽  
P Glycoprotein ◽  
Intracellular Glutathione ◽  
Human Larynx ◽  
Glutathione S Transferases ◽  
Human Larynx Carcinoma

The confluence-dependent resistance of human larynx carcinoma HEp-2 cells to hydrogen peroxide and a new antitumor drug based on the combination of vitamins C and B12b was studied. It was found that this resistance in growing cells is suppressed by the disruption of intercellular contacts by EGTA and is related neither to the activity of P-glycoprotein nor to the content of intracellular glutathione and the activities of glutathione S-transferases, glutathione peroxidase and glutathionine reductase. Here we showed that the level of expression of the small heat shock protein hsp27, which is known to protect cells from a variety of stresses associated with apoptosis, in growing confluent cells both in the presence and absence of the vitamins B12b and C is much higher (about 20–25 times) than in nonconfluent cells. Taken together, the results suggest that the confluence-dependent resistance of cells to the combination of vitamins C and B12b and to hydrogen peroxide is mediated by hsp27 overexpression, which is activated via cell-cell adhesion.

Zinc phthalocyanine-conjugated with bovine serum albumin mediated photodynamic therapy of human larynx carcinoma

Laser Physics ◽  
2016 ◽  
Vol 26 (10) ◽  
pp. 105601 ◽  
Author(s):  
E P O Silva ◽  
E D Santos ◽  
C S Gonçalves ◽  
M A G Cardoso ◽  
C P Soares ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Bovine Serum Albumin ◽  
Serum Albumin ◽  
Bovine Serum ◽  
Zinc Phthalocyanine ◽  
Larynx Carcinoma ◽  
Human Larynx ◽  
Human Larynx Carcinoma
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