scholarly journals Standard Strain and Strain Rate by Two-Dimensional Speckle Tracking in Agoutis (Dasyprocta prymnolopha) Anesthetized with Ketamine and Xylazine

2017 ◽  
Vol 45 (1) ◽  
pp. 12
Author(s):  
Renan Paraguassu de Sá Rodrigues ◽  
Gerson Tavares Pessoa ◽  
Laecio Da Silva Moura ◽  
Andrezza Braga Soares da Silva ◽  
Francisco Das Chagas Araújo Sousa ◽  
...  
Keyword(s):  
Strain Rate ◽  
Speckle Tracking ◽  
Acute Stress ◽  
Total Sample ◽  
The Body ◽  
Human Beings ◽  
Mean Values ◽  
Strain And Strain Rate ◽  
Radial Profiles ◽  
The Mean

Background: The agouti (Dasyprocta prymnolopha, Wagler, 1831) is a wild rodent widely found throughout America which has stood out as a good animal model for scientific investigations. The aim of this study was to study the cardiovascular function of chemically contained agoutis, by performing echocardiographic examinations and measuring Strain and Strain Rate by Speckle Tracking to obtain reference values for the species and verify the applicability of these animals as models for the study of cardiovascular changes in humans.Materials, Methods & Results: It was selected 16 animals, sedated by the combination of ketamine hydrochloride and xylazine and submitted to transthoracic echocardiography. To obtain the standard measurements, B, M and Doppler mode images were taken. The analysis of the radial and longitudinal myocardial deformation of the left ventricle was carried out. The right parasternal window was used for access to the short cardiac axis and the left for access to the long axis. Six radial profiles of strain (ST) and Strain rate (SR) values were obtained, corresponding to the mean of the values for each segment. A total of 18 myocardial segments were analyzed for each specimen and the mean values were used to compose the statistical analysis. The comparison of the means between the genders did not show statistical difference, being the other statistical treatments based on the total sample of 16 animals. The variables that showed statistically significant correlation coefficients in relation to weight were: LA, LA/AO, HR, AVmax, E’ wave, E/IVRT (P > 0.05). HR showed a positive correlation with IVSd (r = 0.51), EPSS (r = 0.55) and E’ wave (r = 0.68); negative with IVRT (r = - 0.41), A wave (r = - 0.54), AVmax (r = - 0.53) and Pmax (r = - 0.65).Discussion: Although presumptively normal echocardiographic values were reported for not anesthetized agoutis, this was the first study to show the measurement of these variables for chemically contained agoutis, in addition to the use of Strain and strain rate by speckle tracking in the assessment of cardiac function. The sudden exposure of an external stimulus (environmental or physical) to which the body is not adapted can trigger an acute stress, and its effects may interfere significantly in the measurement of hemodynamic variables, justifying the need for chemical containment. The values found for the thickness of agoutis cardiac walls and chambers obtained in M mode, both in systole and in diastole, when compared with mammals of different size, confirm the positive linear correlation between body weight and cardiac dimensions for the various evaluated parameters. The velocity obtained by the Strain radial for the apical systolic peak was slightly lower than that obtained for the basal systolic peak, while the opposite was observed for the circumferential Strain, which showed apical peak greater than the basal peak, also to the found for human beings. The values obtained for circumferential, radial and longitudinal strain for agoutis were within the ranges of normality observed in healthy domestic animals and humans.

scholarly journals Normal Ranges of Right Atrial Strain and Strain Rate by Two-Dimensional Speckle-Tracking Echocardiography: A Systematic Review and Meta-Analysis

2021 ◽  
Vol 8 ◽  
Author(s):  
Ali Hosseinsabet ◽  
Roshanak Mahmoudian ◽  
Arash Jalali ◽  
Reza Mohseni-Badalabadi ◽  
Tahereh Davarpasand
Keyword(s):  
Systematic Review ◽  
Strain Rate ◽  
Speckle Tracking ◽  
Speckle Tracking Echocardiography ◽  
Meta Analysis ◽  
The Body ◽  
Right Atrial ◽  
Normal Range ◽  
Strain And Strain Rate ◽  
2D Speckle Tracking

Background: Normal range values of right atrial (RA) phasic function markers are essential for the identification of normal and abnormal values, comparison with reference values, and the clinical meaning of obtained values. Accordingly, we aimed to define the normal range values of RA phasic function markers obtained by 2D speckle-tracking echocardiography through a meta-analysis and determine the main sources of heterogeneity among reported values.Methods: PUBMED, SCOPUS, and EMBASE databases were searched for the following keywords: “right atrial/right atrium” and “strain/speckle/deformation” and “echocardiography.” Studies were selected that included a human healthy adult group without any cardiovascular diseases or risk factors and that were written in the English language. For the calculation of each marker of RA phasic functions, a random-effect model was used. Meta-regression was employed to define the major sources of variabilities among reported values.Results: Fifteen studies that included 2,469 healthy subjects were selected for analysis. The normal range values for RA strain and strain rate were 42.7% (95% CI, 39.4 to 45.9%) and 2.1 s−1 (95% CI, 2.0 to 2.1 s−1) during the reservoir phase, respectively, 23.6% (95% CI, 20.7 to 26.6%) and −1.9 s−1 (95% CI, −2.2 to −1.7 s−1) during the conduit phase, correspondingly, and 16.1% (95% CI, 13.6 to 18.6%) and −1.8 s−1 (95% CI, −2.0 to −1.5 s−1) during the contraction phase, respectively. The sources of heterogeneity for the normal range of these markers were the number of participants, the type of software, the method of global value calculation, the right ventricular fractional area change, the left ventricular (LV) ejection fraction, the RA volume index, sex, the heart rate, the diastolic blood pressure, the body mass index, and the body surface area.Conclusions: Using 2D speckle-tracking echocardiography, we defined normal values for RA phasic function markers and identified the sources of heterogeneity as demographic, anthropometric, hemodynamic, and echocardiography factors.Systematic Review Registration:https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42021236578, identifier: CRD42021236578.

Behavior of fetal longitudinal myocardial fibers assessed by speckle tracking to obtain strain and strain rate values for low-risk pregnancies

2020 ◽  
Vol 48 (2) ◽  
pp. 144-152
Author(s):  
Mariana Biancardi ◽  
Renato Augusto Moreira de Sa
Keyword(s):  
Strain Rate ◽  
Gestational Age ◽  
Speckle Tracking ◽  
Age Groups ◽  
Cross Sectional Study ◽  
Observer Agreement ◽  
Cross Sectional ◽  
Strain And Strain Rate ◽  
Significant Difference ◽  
Myocardial Fibers

AbstractObjectiveTo analyze the behavior of fetal longitudinal myocardial fibers assessed by speckle tracking (STE) after fetal viability.MethodsA cross-sectional study was performed in 156 women with normal singleton pregnancies from 22 to 31 weeks of gestation. Strain (S) and strain rate (SR) values were measured in both ventricles during the fetal cardiac cycle. The population was divided into five gestational age groups based on 2-week intervals. The correlations of maternal variables with the S and SR variables and intra-observer analysis were performed.ResultsThere was a significant difference in the S and SR values of the left ventricle (LV) among the gestational age groups (P = 0.007). Significantly higher S and SR values were observed in early age groups demonstrating reductions in LV S and SR values at 26 weeks, followed by stabilization. For the right ventricle (RV), there was no significant difference between gestational age groups. Significant intra-observer agreement was observed for S values of the RV (P = 0.008) and LV (P = 0.0004) and SR values of the RV (P = 0.0001) and LV (P = 0.015).ConclusionDecreases in the S and SR values of the LV occurred after 26 weeks, followed by stabilization. No significant difference was observed in the S or SR value of the RV among the gestational age groups, and no significant association of any maternal variable evaluated with S and SR values was observed. Significant intra-observer agreement was obtained among the results.

Correlation of Serum Biomarkers in Adults with Single Ventricles with Strain and Strain Rate Using 2D Speckle Tracking

2012 ◽  
Vol 8 (3) ◽  
pp. 255-265 ◽  
Author(s):  
Ali N. Zaidi ◽  
Leah White ◽  
Roger Holt ◽  
Mary Cismowski ◽  
Lisa Nicholson ◽  
...  
Keyword(s):  
Strain Rate ◽  
Speckle Tracking ◽  
Serum Biomarkers ◽  
Strain And Strain Rate ◽  
2D Speckle Tracking

scholarly journals Reproducibility and feasibility of right ventricular strain and strain rate (SR) as determined by myocardial speckle tracking during high-intensity upright exercise: a comparison with tissue Doppler-derived strain and SR in healthy human hearts

2014 ◽  
Vol 1 (1) ◽  
pp. 31-41 ◽  
Author(s):  
Rachel N Lord ◽  
Keith George ◽  
Helen Jones ◽  
John Somauroo ◽  
David Oxborough
Keyword(s):  
Right Ventricular ◽  
Strain Rate ◽  
Exercise Intensity ◽  
Speckle Tracking ◽  
Tissue Doppler ◽  
Healthy Human ◽  
Velocity Imaging ◽  
Strain And Strain Rate ◽  
Right Ventricular Strain ◽  
Progressive Exercise

This study aimed to establish feasibility for myocardial speckle tracking (MST) and intra-observer reliability of both MST and tissue velocity imaging (TVI)-derived right ventricular (RV) strain (ε) and strain rate (SR) at rest and during upright incremental exercise. RV ε and SR were derived using both techniques in 19 healthy male participants. MST-derived ε and SR were feasible at rest (85% of segments tracked appropriately). Feasibility reduced significantly with progressive exercise intensity (3% of segments tracking appropriately at 90% maximum heart rate (HRmax)). Coefficient of variations (CoVs) of global ε values at rest was acceptable for both TVI and MST (7–12%), with low bias and narrow limits of agreement. Global SR data were less reliable for MST compared with TVI as demonstrated with CoV data (systolic SR=15 and 61%, early diastolic SR=16 and 17% and late diastolic SR=26 and 31% respectively). CoVs of global RV ε and SR obtained at 50% HRmax were acceptable using both techniques. As exercise intensity increased to 70 and 90% HRmax, reliability of ε and SR values reduced with larger variability in MST. We conclude that RV global and regional ε and SR data are feasible, comparable and reliable at rest and at 50% HRmax using both MST and TVI. Reliability was reduced during higher exercise intensities with only TVI acceptable for clinical and scientific use.

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