Leucoplasia: revisão de literatura e apresentação de caso clínico

Leucoplakia is a clinica' term that refers to an alteration on the oral mucosa with the appearance of white patchers that are firmly adhered and cannot be classified as any other diagnosable discase. They are considered premalignant lesions due to the increase in the risk of malignant transformation. In this case, around 4% to 6% of the lesions evolve to cancer. Then, it is necessary to estabilish a correct and early diagnose and also a precise treatment to reach good results. The periodical control of the patients that show this kind of alteration is extremely important. The aim of this study is to discuss the possible ethiological agents, clinical and histopathological aspects as well as, the treatment and prognoses through literature review, illustrating with a clinical case.

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Features of redox homeostasis in patients with liver cirrhosis (literature review and clinical case description)

Acta Medica Leopoliensia ◽

10.25040/aml2020.01.070 ◽

2020 ◽

Vol 26 (1) ◽

pp. 70-86

Author(s):

M.O. Abrahamovych ◽

◽

O.O. Abrahamovych ◽

O.P. Fayura ◽

L.R. Fayura ◽

...

Keyword(s):

Liver Cirrhosis ◽

Literature Review ◽

Clinical Case ◽

Redox Homeostasis ◽

Case Description

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Symptomatic azygous vein thrombosis: Clinical case and literature review

Archivos de Bronconeumología (English Edition) ◽

10.1016/j.arbr.2021.05.003 ◽

2021 ◽

Author(s):

Angela Lopez-Bauza ◽

Luis Jara-Palomares

Keyword(s):

Literature Review ◽

Clinical Case ◽

Azygous Vein ◽

Vein Thrombosis

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A Clinicopathologic and Epidemiologic Study of Chronic White Lesions in the Oral Mucosa

Ear Nose & Throat Journal ◽

10.1177/014556131709600804 ◽

2017 ◽

Vol 96 (8) ◽

pp. E13-E17

Author(s):

Sampurna Ghosh ◽

Sudipta Pal ◽

Soumya Ghatak ◽

Somnath Saha ◽

Surajit Biswas ◽

...

Keyword(s):

Oral Mucosa ◽

Epidemiologic Study ◽

Significant Risk ◽

Significant Risk Factor ◽

Premalignant Lesions ◽

Excision Biopsy ◽

Severe Dysplasia ◽

Cross Sectional ◽

Malignant Lesions ◽

Tobacco Chewing

Invasive oral squamous cell carcinoma is often preceded by the presence of clinically identifiable premalignant changes of the oral mucosa, including white lesions. We conducted a cross-sectional, observational study to assess the clinicopathologic and epidemiologic aspects of chronic oral mucosal white lesions to determine the necessity of early biopsy in these cases. Our study population was made up of 77 patients—50 males and 27 females, aged 15 to 70 years (mean: 42.9)—who presented with white lesions persisting for at least 4 weeks. All but 3 patients underwent a biopsy; the 3 exceptions were diagnosed with smear-proven candidiasis. Patients with moderate or severe dysplasia underwent an excision biopsy. The buccal mucosa was the single most common site of white lesions, occurring in 15 patients (19.5%), although 21 patients (27.3%) exhibited a diffuse involvement of the oral mucosa. Of the 77 patients, 59 (76.6%) had concerning findings: premalignant lesions in 45 patients (58.4%) and malignant lesions in 14 (18.2%). Also, dysplasia was seen in 8 patients (10.4%), all of whom had premalignant lesions. Tobacco chewing (p = 0.008) and betel quid chewing (p = 0.029) were significantly associated with the development of premalignant and malignant lesions; a longer duration of tobacco chewing (≥10 yr) was significantly associated with a higher risk of malignant but not premalignant lesions (p = 0.031). Finally, illiteracy was a significant risk factor for premalignant and malignant lesions (p = 0.03). Our findings support the necessity of biopsy in every case. Early detection of oral carcinoma by biopsy of all oral white lesions would not only prevent patients from undergoing disfiguring surgery and chemoradiation, but it also would increase the 5-year survival rate.

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Papillary squamous cell carcinoma of the oral mucosa: a clinicopathologic and immunohistochemical study of 12 cases and literature review

Annals of Diagnostic Pathology ◽

10.1016/j.anndiagpath.2012.04.005 ◽

2013 ◽

Vol 17 (1) ◽

pp. 18-21 ◽

Cited By ~ 12

Author(s):

Yewei Ding ◽

Liwei Ma ◽

Linjun Shi ◽

Jinqiu Feng ◽

Wei Liu ◽

...

Keyword(s):

Squamous Cell Carcinoma ◽

Literature Review ◽

Cell Carcinoma ◽

Oral Mucosa ◽

Squamous Cell ◽

Immunohistochemical Study ◽

Papillary Squamous Cell Carcinoma

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Applicability of Moyers analysis in mixed dentition: A systematic review

Dental Press Journal of Orthodontics ◽

10.1590/s2176-94512013000600015 ◽

2013 ◽

Vol 18 (6) ◽

pp. 100-105 ◽

Cited By ~ 5

Author(s):

Mariana de Aguiar Bulhões Galvão ◽

Gladys Cristina Dominguez ◽

Sérgio Thomaz Tormin ◽

Alex Akamine ◽

André Tortamano ◽

...

Keyword(s):

Systematic Review ◽

Literature Review ◽

Clinical Case ◽

Case Reports ◽

Mixed Dentition ◽

Inclusion Criteria ◽

Exclusion Criteria ◽

Theoretical Probability ◽

Study Population ◽

Mixed Dentition Analysis

INTRODUCTION: Moyers analysis is widely used for analyzing mixed dentition, however, the accuracy of its theoretical probability tables has been recently questioned. Taking into consideration the fact the mixed dentition analysis is of paramount importance to precisely determine the space needed for alignment of canines and premolars, this research aimed at objectively assessing in the literature such an important step for orthodontic diagnosis. METHODS: A computerized search involving articles published on PubMed and Lilacs between 1990 and September, 2011 was conducted in accordance with the method described in the Cochrane 5.1.0 handbook. RESULTS: The research resulted in a sample composed of 629 articles. The inclusion criteria were: Articles using the Moyers analysis with a sample greater or equal to 40 patients. Conversely, the exclusion criteria were: Dental casts of patients with syndromes or oral cleft, researches conducted with a literature review, only, or clinical case reports and researches conducted before 1990. For this systematic review, 19 articles were selected. CONCLUSION: Based on the literature available, we can conclude that the Moyers mixed dentition analysis must be carefully used, since the majority of the articles analyzed showed that the probability of 75% was not as accurate as expected, leading to the need of adapting the probability levels depending on the study population.

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