scholarly journals Implementation of pharmacogenomic testing service through community pharmacy in the Netherlands: results from an early service evaluation

Author(s):  
Tracey Thornley ◽  
Bernard Esquivel ◽  
David Wright ◽  
Hidde van den Dop ◽  
Charlotte Kirkdale ◽  
...  
Pharmacy ◽  
2021 ◽  
Vol 9 (1) ◽  
pp. 38
Author(s):  
Tracey Thornley ◽  
Bernard Esquivel ◽  
David J. Wright ◽  
Hidde van den Dop ◽  
Charlotte L. Kirkdale ◽  
...  

Community pharmacy services have evolved to include medical and pharmaceutical interventions alongside dispensing. While established pharmacogenomic (PGx) testing is available throughout the Netherlands, this is primarily based in hospital environments and for specialist medicines. The aim of this work was to describe how best to implement PGx services within community pharmacy, considering potential barriers and enablers to service delivery and how to address them. The service was implemented across a selection of community pharmacies in the Netherlands. Data were captured on test outcomes and through a pharmacist survey. Following testing, 17.8% of the clinical samples were recommended to avoid certain medication (based on their current medicines use), and 14.0% to have their dose adjusted. Pre-emptive analysis of genotyped patients showed that the majority (99.2%) had actionable variants. Pharmacists felt confident in their operational knowledge to deliver the service, but less so in applying that knowledge. Delivering the service was believed to improve relationships with other healthcare professionals. These results add to the evidence in understanding how PGx can be delivered effectively within the community pharmacy environment. Training pharmacists in how to respond to patient queries and make clinical recommendations may enhance service provision further.


BMJ Open ◽  
2016 ◽  
Vol 6 (10) ◽  
pp. e012532 ◽  
Author(s):  
Hamde Nazar ◽  
Steven Brice ◽  
Nasima Akhter ◽  
Adetayo Kasim ◽  
Ann Gunning ◽  
...  

Pharmacy ◽  
2020 ◽  
Vol 8 (4) ◽  
pp. 231
Author(s):  
Charlotte L. Kirkdale ◽  
Zoe Archer ◽  
Tracey Thornley ◽  
David Wright ◽  
Mette Valeur ◽  
...  

Early identification and treatment of malignant melanoma is crucial to prevent mortality. The aim of this work was to describe the uptake, profile of users and service outcomes of a mole scanning service in the community pharmacy setting in the UK. In addition, health care costs saved from the perspective of general practice were estimated. The service allowed patients to have concerning skin lesions scanned with a dermatoscopy device which were analyzed remotely by clinical dermatology specialists in order to provide recommendations for the patient. Patients were followed up to ascertain the clinical outcome. Data were analyzed for 6355 patients and 9881 scans across 50 community pharmacies. The majority of the scans required no further follow-up (n = 8763, 88.7%). Diagnosis was confirmed for 70.4% (n = 757/1118) of scans where patients were recommended to seek further medical attention. Of these, 44.3% were ultimately defined as normal (n = 335) and 6.2% as malignant melanoma (n = 47/757). An estimated 0.7% of scans taken as part of the service led to a confirmed diagnosis of malignant melanoma. This service evaluation has shown that a mole scanning service available within community pharmacies is effective at triaging patients and ultimately playing a part in identifying diagnoses of malignant melanoma.


PLoS ONE ◽  
2020 ◽  
Vol 15 (3) ◽  
pp. e0230343
Author(s):  
Hamde Nazar ◽  
Cerys Evans ◽  
Nicole Kyei ◽  
Laura Lindsey ◽  
Zachariah Nazar ◽  
...  

2017 ◽  
Vol 29 (5) ◽  
pp. 474-482 ◽  
Author(s):  
Gary G Whitlock ◽  
Daniel C Gibbons ◽  
Nick Longford ◽  
Michael J Harvey ◽  
Alan McOwan ◽  
...  

A service evaluation of Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) testing and result notification in patients attending a rapid testing service (Dean Street Express [DSE]) compared with those attending an existing ‘standard’ sexual health clinic (56 Dean Street [56DS]), and modelling the impact of the new service from 1 June 2014 to 31 May 2015. Primary outcome: time from patients’ sample collection to notification of test results at DSE compared with 56DS. Secondary outcomes estimated using a model: number of transmissions prevented and the number of new partner visits avoided and associated cost savings achieved due to rapid testing at DSE. In 2014/15, there were a total of 81,352 visits for CT/NG testing across 56DS (21,086) and DSE (60,266). Rapid testing resulted in a reduced mean time to notification of 8.68 days: 8.95 days for 56DS (95% CI 8.91–8.99) compared to 0.27 days for DSE (95% CI 0.26–0.28). Our model estimates that rapid testing at DSE would lead to 196 CT and/or NG transmissions prevented (2.5–97.5% centile range = 6–956) and lead to annual savings attributable to reduced numbers of partner attendances of £124,283 (2.5–97.5% centile range = £4260–590,331). DSE, a rapid testing service for asymptomatic infections, delivers faster time to result notification for CT and/or NG which enables faster treatment, reduces infectious periods and leads to fewer transmissions, partner attendances and clinic costs.


Pharmacy ◽  
2020 ◽  
Vol 8 (4) ◽  
pp. 182
Author(s):  
Rachel Hardin ◽  
Pheli Roberts ◽  
Brooke Hudspeth ◽  
Angela Tracy ◽  
Lauren Baldwin ◽  
...  

Point-of-care testing is becoming increasingly commonplace in community pharmacy settings. These tests are often used in the management of chronic disease, such as blood sugar, hemoglobin A1c and lipid levels, but can also be used for acute conditions such as influenza infection and group A streptococcus pharyngitis. When used for these acute infections, point-of-care tests can allow for pharmacist-initiated treatment. In this study, an influenza point-of-care testing service was developed and implemented in a chain community pharmacy setting and a retrospective review was conducted to assess the service. Of patients tested, 29% tested positive for influenza A and/or B; 92% of patients testing positive received a prescription as a result. While health insurance cannot be billed for the service due to current pharmacy reimbursement practices, this did not appear to negatively affect patient willingness to participate. As point-of-care testing services become more commonplace in community pharmacy settings, patient awareness will similarly increase and allow for more widespread access to acute outpatient care.


BMJ Open ◽  
2016 ◽  
Vol 6 (8) ◽  
pp. e011269 ◽  
Author(s):  
Hamde Nazar ◽  
Zachariah Nazar ◽  
Jill Simpson ◽  
Andre Yeung ◽  
Cate Whittlesea

2005 ◽  
Vol 39 (10) ◽  
pp. 1720-1725 ◽  
Author(s):  
JW Foppe van Mil

OBJECTIVE: To describe the pharmaceutical care activities and research in community pharmacy in the Netherlands. FINDINGS: Pharmaceutical care is well advanced in Dutch pharmacy practice. This is largely due to the fact that clinical pharmacy was already an integrated part of community pharmacy practice by the end of the 1980s. Activities of the International Pharmaceutical Federation (FIP), some wholesale companies, and influential individuals in the Netherlands stimulated universities and the Royal Society for the Advancement of Pharmacy to advance the implementation of pharmaceutical care. DISCUSSION: Not all pharmacies in the Netherlands provide pharmaceutical care at the same level, although medication surveillance (concurrent and prospective medication analysis) is part of everyday practice. Implementation of quality assurance systems in community pharmacy practice could be helpful in assuring high levels of care. Similar to those in other countries, Dutch pharmacists are torn between the wish to provide pharmaceutical care and economic considerations, although the financial status of most pharmacies is still (very) healthy. New entrants into the market, such as supermarket and pharmacy chains, seem to put little emphasis on care provision. CONCLUSIONS: Pharmaceutical care has been implemented in many Dutch community pharmacies, but not everywhere to the same extent. Due to excellent automated medication surveillance; structured, high-quality medication counseling; and the fact that patients usually visit the same pharmacy, Dutch patients are well protected against many drug-related problems.


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