scholarly journals Cutis verticis gyrata: three cases illustrating three different etiologies

2021 ◽  
Author(s):  
Amal Chamli ◽  
Meriem Jones ◽  
Takwa Bacha ◽  
Noureddine Litaiem ◽  
Faten Zeglaoui
Keyword(s):  
Cerebral Cortex ◽  
Cutis Verticis Gyrata ◽  
The Face ◽  
Neurocutaneous Syndrome ◽  
Secondary Form ◽  
Primary Form

Cutis Vertcis gyrata is an uncommon neurocutaneous syndrome characterized by excessive growth of the skin of the scalp or the face, forming folds of similar aspect to cerebral cortex gyri. Three categories have been individualized: the primary form, essential or non-essential, and the secondary form.

scholarly journals IMMUNODIAGNOSIS IN MEMBRANOUS NEPHROPATHY

2020 ◽  
Vol 73 (9) ◽  
pp. 1861-1866
Author(s):  
Magdalena Ratajczak ◽  
Ewa Poleszak ◽  
Tomasz Chrościcki
Keyword(s):  
Membranous Nephropathy ◽  
Antinuclear Antibodies ◽  
Aim Analysis ◽  
Non Invasive ◽  
Phospholipase A2 Receptor ◽  
Secondary Form ◽  
Stage Renal Disease ◽  
End Stage ◽  
Receptor Antibodies ◽  
Primary Form

One of the diseases leading to chronic end-stage renal disease is membranous nephropathy (MN). The main cause of this disease is the formation of antibodies to foreign and native antigens. Membranous nephropathy can be conventionally divided into 2 types: primary form (when the primary disease is unknown) and secondary form. Detection of appropriate antibodies is one of the methods to recognize and differentiate primary and secondary forms. A large role in non-invasive diagnosis of MN and differentiation of the primary form from the secondary play antinuclear antibodies (ANA), antibodies against granulocyte cytoplasm (ANCA), antiglomerular basement antibodies (anti-GBM) and phospholipase A2 receptor antibodies (anti-PLA2R). Differentiation matters when choosing a treatment choice. In the primary form, it is immunosuppression, and in the form of secondary treatment, it consists in curing or controlling diseases that can cause symptoms of MN. The aim: Analysis of serological methods helpful in immunodiagnosis of membranous nephropathy.

Primary and secondary effects of processing instruction on Spanish clitic pronouns

2015 ◽  
Vol 53 (2) ◽  
Author(s):  
Justin White
Keyword(s):  
Adult Learners ◽  
Future Research ◽  
Secondary Effects ◽  
Processing Instruction ◽  
Secondary Target ◽  
Structured Input ◽  
Target Form ◽  
Secondary Form ◽  
Primary And Secondary Effects ◽  
Primary Form

AbstractThis study investigates the effects of token item frequency in Structured Input activities on both a primary target form (Spanish accusative clitics) and a secondary target form (Spanish dative clitics). Participants included 460 adult learners enrolled in a beginning-level Spanish language course and they were exposed to either 40, 60, 80, 100, 120, or 140 target form tokens. This study included a pretest, immediate posttest, and a delayed posttest measuring interpretation and production of both primary and secondary target forms. Findings reveal that primary form interpretation effects across all frequencies, however, production findings present themselves with the 60 and 80 token groups only. Secondary form interpretation findings reveal themselves across all frequency levels with the exception of the lowest frequency investigated (40 tokens) and secondary form production mirror those found in previous studies on the same forms. As such, we discuss the theoretical and methodological ramifications of these findings as well as directions for future research.

Studies on Differential Proteins of Two Forms of Xenorhabdus Nematophilus

2019 ◽  
Vol 13 (4) ◽  
pp. 446-455
Author(s):  
Fengqin Zhang ◽  
Yajie Guo ◽  
Xiongduo Liu ◽  
Yong Liu ◽  
Liuliang Peng ◽  
...  
Keyword(s):  
Metabolic Pathways ◽  
Glutamate Synthase ◽  
Xenorhabdus Nematophila ◽  
Tumor Drug Resistance ◽  
Anti Cancer ◽  
Differential Proteins ◽  
Cytotoxic Compounds ◽  
Specific Proteins ◽  
Secondary Form ◽  
Primary Form

As an entomopathogenic bacterium, Xenorhabdus nematophila (X. nematophila) can be parasitic in the gut of entomopathogenic nematodes. Compared with the primary form of X. nematophila, its secondary form has more differences in physiological characteristics and metabolic pathways, such as insecticide, antibacterial, anti-cancer and other functions. Many studies about the application of X. nematophila as biological agents in ecological environment have been reported. However, its pathogenic mechanism and specific functional molecules remain to be studied. Therefore, this study is dedicated to research differential proteins between the primary and the secondary bacteria with iTRAQ technique to further explore the functional mechanism and functional proteins of X. nematophila. A total number of 367 differentially expressed proteins were detected with iTRAQ technique. Besides Xenocoumacin and Xnph1 proteins that had been widely studied by some scholars, other specific proteins in primary bacteria excavated are as follows: Xcn and Xnph1 proteins with antibacterial property, proteins related to the attachment of X. nematophila to the host insects including flagellin, fimbrial adaptor, fimbrial adhesion and capsular synthesis regulator component B, glutamate synthase that plays an important role in multiple metabolic pathways in the primary bacteria, multidrug resistance secretion proteins with the property of tumor drug resistance and defense effects against cytotoxic compounds produced by normal cells and malignant cells.

scholarly journals Pachydermoperiostosis (PDP): A Case Report

2021 ◽  
pp. 1-8
Author(s):  
Abdulameer M. Abu Nailah ◽  
Islam A. M. Abu-Nayla ◽  
Umniyah A. M. Abu-Nayla
Keyword(s):  
Case Report ◽  
Hypertrophic Osteoarthropathy ◽  
Primary Hypertrophic Osteoarthropathy ◽  
Digital Clubbing ◽  
Cutis Verticis Gyrata ◽  
Incomplete Form ◽  
Bone Abnormalities ◽  
Primary Form

Abstract Pachydermoperiostosis (PDP) is the primary form of hypertrophic osteoarthropathy which accounts for 5% of all cases of the disorder. It is a rare hereditary disorder that is associated with digital clubbing, polyarthritis, cutis verticis gyrata, Seborrhea, eyelid ptosis, and hyperhidrosis. In this case report, we discussed a case of an incomplete form of primary hypertrophic osteoarthropathy characterised by evidence of bone abnormalities without pachydermia. Keywords: Pachydermoperiostosis, hypertrophic osteoarthropathy, periostosis.

Pathological and anatomical changes in the cerebral cortex in two cases of premature dementia (Dementia praecox)

1903 ◽  
Vol 3 (3-4) ◽  
pp. 149-150
Author(s):  
A. L. Lyubushin
Keyword(s):  
Cerebral Cortex ◽  
Microscopic Examination ◽  
Cortical Layer ◽  
Dementia Praecox ◽  
Pathological Anatomy ◽  
Anatomical Changes ◽  
Early Dementia ◽  
The Face ◽  
History Of ◽  
The Brain

Journal of neuropathology and psychiatry named after S. S. Korsakov, book. 1 and 2 1902The study of the literature on this issue (Kahlbaum, Kiernan, Chizh, Alzheimer) leads to the conclusion that the evidence on the pathological anatomy of early dementia is extremely inadequate and unclear. The author introduces the history of illness to two patients who suffered from early dementia. Both cases ended in death; at autopsy with microscopic examination, they appeared on the face: in one case, the brain was full-blooded, slightly swollen, atrophy of the gyrus of the brain and atrophy of the cortical layer, expressed equally in all lobes of the brain. The lateral ventricles are slightly distended and contain a significant amount of fluid; in another - leptomeningitis sclerotica, Atrophia

scholarly journals Persistent Salmon Patch on the Forehead and Glabellum in a Chinese Adult

2014 ◽  
Vol 2014 ◽  
pp. 1-3
Author(s):  
Alexander K. C. Leung ◽  
Benjamin Barankin ◽  
Kam Lun Hon
Keyword(s):  
Laser Therapy ◽  
Upper Lip ◽  
Vascular Abnormality ◽  
Old Chinese ◽  
Chinese Adult ◽  
The Face ◽  
Neurocutaneous Syndrome

Salmon patches are present in approximately 44% of all neonates. The lesions tend to fade with time and those on the glabellum, eyelids, nose, and upper lip are rarely detected after the age of 6. We report a 33-year-old Chinese female with a salmon patch on the forehead and glabellum. To our knowledge, the occurrence of a salmon patch on the forehead and glabellum in adulthood has not been reported. The persistent salmon patch on the face of an adult is benign and not associated with any neurocutaneous syndrome or underlying vascular abnormality. The color of the lesion can be ameliorated with laser therapy if cosmesis is a concern.

Feet Deformity and Gait Disturbance in a Patient with Pachydermoperiostosis (PDP). Case Study

2019 ◽  
Vol 21 (2) ◽  
pp. 119-128
Author(s):  
Marek Aleksander Synder ◽  
Praveen Malik ◽  
Marek Synder ◽  
Żaneta Andrychowicz ◽  
Munaf A. Hatim Altimimi ◽  
...  
Keyword(s):  
Case Report ◽  
Surgical Treatment ◽  
Surgical Management ◽  
Rare Condition ◽  
Gait Disturbance ◽  
Hypertrophic Osteoarthropathy ◽  
The Face ◽  
Radiological Changes ◽  
Primary Form

Pachydermoperiostosis is a rare condition representing a primary form of hypertrophic osteoarthropathy. It presents in different stages. Patients often overlook early symptoms, because they are benign. The most common manifestations are clubbing of the fingers and toes, skin thickening with characteristic folds on the face and head and widening of joints accompanied by radiological changes. Surgical treatment is not often needed, and, consequently, there are no strict guidelines on surgical management, which is mainly based on case report ana­lysis. This paper presents a case of surgical management of pachydermoperiostosis.

scholarly journals The ner Gene of Photorhabdus: Effects on Primary-Form-Specific Phenotypes and Outer Membrane Protein Composition

2002 ◽  
Vol 184 (11) ◽  
pp. 3096-3105 ◽  
Author(s):  
Keith H. O'Neill ◽  
Declan M. Roche ◽  
David J. Clarke ◽  
Barbara C. A. Dowds
Keyword(s):  
Membrane Protein ◽  
Stationary Phase ◽  
Outer Membrane ◽  
Outer Membrane Protein ◽  
Protein Profile ◽  
Outer Membrane Proteins ◽  
Regulatory Gene ◽  
Phenotypic Switching ◽  
Secondary Form ◽  
Primary Form

ABSTRACT The nematode-bacterium complex of Heterorhabditis-Photorhabdus is pathogenic to insect larvae. The bacteria undergo a form of phenotypic switching whereby the primary form, at the stationary phase of the growth cycle, makes a range of products and has the capacity to support nematode growth, whereas the secondary form does not express these phenotypes. The work described here investigated the mechanism regulating phenotypic variation by transforming the primary cells with secondary-form DNA on a low-copy-number vector and screening for colonies which did not produce the yellow pigment characteristic of primaries. Four transformants all carrying the same gene were found to loose primary-form-specific characteristics, and the gene was sequenced and identified as ner, a regulatory gene in gram-negative bacteria and their phages. Unexpectedly, inactivation of the endogenous gene in the secondaries did not cause them to revert to the primary phenotype, and the gene was expressed in the primary form as well as the secondary form during exponential but not stationary phase and deregulated in the plasmid-bearing primary form. These and other pieces of evidence indicate that the endogenous ner gene is not responsible for the secondary phenotype, but that ner, when overexpressed, can repress expression of primary phenotypes at stationary phase. Inactivation of the endogenous ner gene in the primary form affected the outer membrane protein profile. A number of outer membrane proteins displayed differential accumulation in the primary and secondary forms at stationary phase, and two of the primary-form-specific proteins were absent from the ner primary strain.

Surgical Treatment of Facial Cutis Verticis Gyrata with Direct Excision

2007 ◽  
Vol 11 (1) ◽  
pp. 4-8 ◽  
Author(s):  
Justus P. Beier ◽  
Ulrich Kneser ◽  
Raymund E. Horch
Keyword(s):  
Quality Of Life ◽  
Surgical Treatment ◽  
Facial Skin ◽  
Face Lift ◽  
Cutis Verticis Gyrata ◽  
The Face ◽  
Upper Face ◽  
Upper Face Lift ◽  
Major Reduction

Background: Cutis verticis gyrata (CVG) is a rare deformity of the skin presenting with thick gyrated folds and ridges, involving predominantly parts of the head and the face. Objective: We report on aspects of the surgical treatment of facial CVG based on our experiences with four patients, who had developed a progressive and enormous thickening and an extraordinary strong gyration of the facial skin. Methods: A single or staged repeated straightforward surgical treatment with direct excision of abundant and thickened gyriform folds, in one case accomplished by an upper face-lift, was performed. Results: Direct excision within the lines of tension resulted in a major reduction of the facial skin distortion, a reduced scalp, and facial skin thickening and avoided maceration in all four patients. The quality of life was considerably improved in all patients. Conclusion: Direct excision of gyriform skin is a successful surgical approach to the rare skin deformity of CVG.

Decomposing Isomorphism: What Drives Similarity in the Adoption of New Public Management?

2018 ◽  
Vol 52 (3) ◽  
pp. 375-404 ◽  
Author(s):  
Jun Li ◽  
Ken Chung
Keyword(s):  
Service Delivery ◽  
Public Administration ◽  
Local Governments ◽  
Public Management ◽  
New Public Management ◽  
Discrete Event ◽  
Three Dimensions ◽  
New Public ◽  
The Face ◽  
Primary Form

New public management is a major paradigm in public administration, and its widespread adoption has been explained by institutional theory. However, most studies treat adoption as a discrete event and cannot explain why some organizations are moving away in the face of isomorphic pressure. We investigate three dimensions of isomorphism—convergence, compliance, and commitment—and test their separate effects on interorganizational similarity in adopting private service delivery, a primary form of outsourcing, among U.S. local governments. This study contributes to the literature by demonstrating the multiplicity of isomorphism and by showing how variation occurs in the isomorphic process.

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