scholarly journals Comparison of clinical and laboratory characteristics of viral hepatitis A and E in Montenegro

2010 ◽  
Vol 63 (3-4) ◽  
pp. 175-178
Author(s):  
Dragica Terzic ◽  
Gordana Mijovic ◽  
Brankica Dupanovic ◽  
Nenad Draskovic ◽  
Neda Svirtlih
Keyword(s):  
Viral Hepatitis ◽  
Hepatitis A ◽  
Liver Function Tests ◽  
Hepatitis E ◽  
Mean Value ◽  
Laboratory Parameters ◽  
Barr Virus ◽  
Route Of Transmission ◽  
Epstein Barr ◽  
Commercial Kits

Introduction Hepatitis E has many similarities in with hepatitis A concerning clinical picture, route of transmission and nonexistence of chronicity. Comparison of clinical and laboratory parameters of patients with hepatitis A and E to estimate characteristics of these diseases. Material and methods Total of 54 patients divided into two groups was investigated: 27 had hepatitis A, others had hepatitis E. Detailed history past, clinical examination, liver function tests and ultrasonography of the upper abdomen, were done in all patients. Etiology of viral hepatitis was investigated serologically by enzyme immunoassay (ELISA) using commercial kits for following viruses: Hepatitis A-E viruses, cytomegalovirus, and Epstein-Barr virus. Results Asymptomatic infections (29.6%) and clinical forms without jaundice (59.3%) were more frequent in patients with hepatitis E. Splenomegaly was found more frequent in patients with hepatitis A than in hepatitis E (66.7% vs. 33.3%). Patients with hepatitis E had significantly lower activity of aminotransferases than patients with hepatitis A. A significant increase of gamma-glutamyltranspeptidase was found in patients with hepatitis E (mean value: 120 IU/L). Discussion Our results are in concordance with other reports that hepatitis E virus infection is more common asymptomatic disease than hepatitis A. In addition, hepatocyte necrosis in hepatitis E is less extensive than in hepatitis A measured by the activity of aminotransferases. Contrary to that the value of gamma-glutamyltranspeptidase is more increased in hepatitis E than in hepatitis A without exact explanation uso far. Conclusion Viral hepatitis E and A have differences in some clinical features and laboratory parameters although both diseases principally have resolved without consequences after 6-8 weeks.

scholarly journals Viral Hepatitis: Retrospective Review in a Canadian Pediatric Hospital

2011 ◽  
Vol 2011 ◽  
pp. 1-4 ◽  
Author(s):  
Paulina Cybulska ◽  
Andy Ni ◽  
Carolina Jimenez-Rivera
Keyword(s):  
Viral Hepatitis ◽  
Epstein Barr Virus ◽  
Hepatitis A ◽  
Chart Review ◽  
Clinical Presentation ◽  
Retrospective Chart Review ◽  
Barr Virus ◽  
Mild Abdominal Pain ◽  
Epstein Barr ◽  
Acute And Chronic Hepatitis

Introduction. Clinical presentation of viral hepatitis ranges from mild symptoms to fulminant hepatitis. Our aim is to describe clinical presentation and outcomes of children with viral hepatitis from the Eastern Ontario/Western Quebec regions of Canada. Methods. Retrospective chart review of children diagnosed with viral hepatitis at our institution from January 1, 1998, to December 31, 2007. Results. There were 261 charts reviewed, only 64 had a confirmed viral etiology: 34 (53%) hepatitis B (HBV), 16 (25%) hepatitis C (HCV), 4 (6.3%) hepatitis A (HAV), 7 (11%) cytomegalovirus (CMV), and 3 (4.7%) Epstein-Barr virus (EBV). Children with HBV presented at a mean age of 6.4±4.6 years. Spontaneous seroconversion (appearance of HBVeAb and loss of HBVeAg) occurred in 21/34 (61.7%). Children with acute hepatitis (HAV, CMV, and EBV) presented with mild abdominal pain, jaundice, and fevers. Overall outcome was excellent. Conclusion. Acute and chronic hepatitis in children has a benign course; moreover, HBV spontaneous seroconversion is common in pediatric patients.

scholarly journals Biochemical Parameters in Common Viral Hepatitis

1970 ◽  
Vol 11 (1) ◽  
pp. 42-45 ◽  
Author(s):  
Md Ashraf-Uz-Zaman ◽  
Bilquis Ara Begum ◽  
Humaira Binte Asad ◽  
Shafia Sharmin Moutoshi ◽  
Md Nasiruddin
Keyword(s):  
Hepatitis C ◽  
Hepatitis B ◽  
Viral Hepatitis ◽  
Biochemical Parameters ◽  
Hepatitis A ◽  
Serum Alkaline Phosphatase ◽  
Hepatitis E ◽  
Mean Value ◽  
Serum Bilirubin Level ◽  
Hepatitis D

Viral hepatitis is the inflammation of the liver caused by hepatitis viruses. The most common causes of viral hepatitis are the five unrelated hepatotropic viruses Hepatitis A, Hepatitis B, Hepatitis C, Hepatitis D, and Hepatitis E. The aim of this study is to assess the biochemical parameters in viral hepatitis which varies with respect to the different types of viral hepatitis. Sex of the patient affected by Hepatitis A was almost similar in male and female, being 9 (45%) and 11 (55%) in respectively. But in contrast, more than eighty per cent (85%) Hepatitis-E affected population was male. Similar scenario was found in Hepatitis B And C infection (Male- 75%,67%, Female 25,35%). Mean value with standard deviation (±SD) of serum bilirubin level was highest in Hepatitis E (251 ± 125.19 ìmol/l). Value of serum ALT in hepatitis E was found to be 1794 U/l (highest), hepatitis B 1362 U/l hepatitis C are 135.45 U/L,. Serum aspartate aminotransferase (S.AST) is also raised in all types of vira hepatitis but more in Hepatitis E (765 U/l) and Hepatitis B (430 U/l). Serum Alkaline Phosphatase (ALP) was raised significantly in Hepatitis B (240 U/l). The prothombin time was more altered in Hepatitis-E (22.7seconds) and Hepatitis-B (18.5 seconds). There was no significant alteration in serum protein level. So, it can be concluded that derangement of biochemical parameters in patients suffering from common types of viral hepatitis is more in HEV and HBV and comparatively less in HAV and HCV. Keywords: Viral hepatitis, hepatitis A, hepatitis B, hepatitis C, hepatitis D, hepatitis E DOI:10.3329/jom.v11i1.4268 J Medicine 2010: 11: 42-45

Viral Hepatitis: A, B, C, D and E—Infection

1992 ◽  
Vol 13 (6) ◽  
pp. 203-212
Author(s):  
Saul Krugman
Keyword(s):  
Hepatitis B ◽  
Viral Hepatitis ◽  
Hepatitis A ◽  
Venereal Disease ◽  
Hepatitis E ◽  
Infectious Hepatitis ◽  
Yellow Fever Vaccine ◽  
Hepatitis D ◽  
Varicella Zoster ◽  
Barr Virus

Viral hepatitis is caused by at least five etiologically and immunologically distinct viruses: hepatitis A (HAV), hepatitis B (HBV), hepatitis C (HCV), hepatitis D (HDV), and hepatitis E (HEV). The clinical, epidemiologic, and immunologic features of these five forms of viral hepatitis may be similar or different. Hepatitis also may occur during the course of disease caused by cytomegalovirus, Epstein-Barr virus, herpes simplex virus, varicella-zoster virus, adenoviruses, enteroviruses, rubella virus, arboviruses, and other agents. Hepatitis A is synonymous with "infectious hepatitis," an ancient disease described by Hippocrates and formerly known as epidemic jaundice, acute catarrhal jaundice, and other designations. The fulminant form of the disease was called acute yellow atrophy of the liver. Hepatitis B is synonymous with "serum hepatitis," a disease with a more recent history. The first known outbreak occurred during 1883 among a group of shipyard workers who were vaccinated against smallpox with glycerinated lymph of human origin. Later, an increased incidence of the disease was observed among patients attending venereal disease clinics, diabetes clinics, and other facilities where multiple injections were given with inadequately sterilized syringes and needles contaminated with the blood of a viral carrier. The most extensive outbreak occured in 1942, when yellow fever vaccine containing human serum caused 28 585 cases of hepatitis B infection with jaundice among United Stated military personnel.

scholarly journals Bahaya Penyakit Hepatitis Terhadap Ibu Hamil

2020 ◽  
Author(s):  
listiana tri widiya puspita sari
Keyword(s):  
Epstein Barr Virus ◽  
Hepatitis A ◽  
Hepatitis Virus ◽  
Hepatitis E ◽  
Mumps Virus ◽  
Hepatitis D ◽  
Barr Virus ◽  
Acute Yellow Atrophy ◽  
Acute Fatty Liver ◽  
Epstein Barr

Penyakit Hepatitis adalah peradangan pada hati karena toxin, seperti kimia, obat atau agen penyebab infeksi. Penyakit ini disebabkan oleh beberapa jenis virus yang menyerang dan menyebabkan peradangan serta merusak sel-sel organ hati manusia. Hepatitis yang berlangsung kurang dari 6 bulan disebut hepatitis akut, hepatitis yang berlangsung lebih dari 6 bulan disebut hepatitis kronis. Hepatitis diketegorikan dalam beberapa golongan, diantaranya hepatitis A, hepatitis B, hepatitis C, hepatitis D, hepatitis E, dan hepatitis G. Hepatitis juga terjadi karena infeksi virus lainnya, seperti mononukleosis itinfeksiosa, demam kuning dan infeksi Virus Mumps, Virus Rubella, Virus Cytomegalovirus, Virus Epstein-Barr, Virus Herpes. Penyebab hepatitis non – virus yang utama adalah alkohol dan obat-obatan. Pada wanita hamil kemungkinan untuk terjangkit hepatitis virus adalah sama dengan wanita tidak hamil pada umur yang sama. Kelainan hepar yang mempunyai hubungan langsung dengan peristiwa kehamilan, ialah : Acute fatty liver of pregnancy (Obstetric acute yellow-atrophy). Infeksi hepatitis virus pada kehamilan tidak berhubungan langsung dengan peristiwa kehamilan, namun tetap memerlukan penanganan khusus, mengingat penyulit-penyulit yang mungkin timbul baik untuk ibu maupun janin. Hepatitis virus sering menimbulakan jaundice pada kehamilan, dengan kemajuan pengobatan saat ini, asam ursodeoxychalic dapat mengurangi kerusakan hati, baik akut maupun kronik.

Acute viral hepatitis presenting as cytomegalovirus, hepatitis E and Epstein–Barr virus IgM antibody positive

2015 ◽  
Vol 21 (2) ◽  
pp. 171-173 ◽  
Author(s):  
Qin Huang ◽  
Xin-Hua Li ◽  
Cuiyun Zhu ◽  
Jingjing Yan ◽  
Zhigang Song ◽  
...  
Keyword(s):  
Viral Hepatitis ◽  
Epstein Barr Virus ◽  
Acute Viral Hepatitis ◽  
Hepatitis E ◽  
Barr Virus ◽  
Igm Antibody ◽  
Cytomegalovirus Hepatitis ◽  
Epstein Barr

scholarly journals Clinical case of mixed infection of Viral hepatitis E and Infectious mononucleosis

2019 ◽  
Vol 18 (4) ◽  
pp. 64-66
Author(s):  
A. L. Bondarenko ◽  
K. G. Korobicyn ◽  
Yu. P. Slobozhaninova
Keyword(s):  
Viral Hepatitis ◽  
Infectious Mononucleosis ◽  
Mixed Infection ◽  
Biochemical Analysis ◽  
Hepatitis E ◽  
Residual Effects ◽  
Acute Tonsillitis ◽  
Barr Virus ◽  
Epstein Barr ◽  
Cytolysis Syndrome

The article considers a case from clinical practice: mixed infection of viral hepatitis E and infectious mononucleosis caused by Epstein-Barr virus in a boy of 15 years. The patient was long observed by a pediatrician with a diagnosis of lacunar tonsillitis, hospitalized on the 10th day of the disease in an infectious diseases hospital with a preliminary diagnosis of infectious mononucleosis. Objectively, in addition to acute tonsillitis, detected polylithionite, hepatosplenomegaly. The biochemical analysis of blood revealed a pronounced cytolysis syndrome, a study on the markers of viral hepatitis (revealed anti-HEV IgM). Discharged on the 28th day of the disease with residual effects.

scholarly journals Acute Viral Hepatitis in Pediatric Age Groups

2014 ◽  
Vol 52 (193) ◽  
pp. 687-691 ◽  
Author(s):  
Sudhamshu KC ◽  
Dilip Sharma ◽  
Nandu Silwal ◽  
Bhupendra Kumar Basnet
Keyword(s):  
Bacterial Infection ◽  
Viral Hepatitis ◽  
Clinical Features ◽  
Hepatitis A ◽  
Acute Viral Hepatitis ◽  
Age Groups ◽  
Hepatitis E ◽  
Laboratory Parameters ◽  
Secondary Bacterial Infection ◽  
Herbal Medications

Introduction: Our clinical experience showed that there has been no decrease in pediatric cases of acute viral hepatitis in Kathmandu. The objective of the study was to analyze the etiology, clinical features, laboratory parameters, sonological findings and other to determine the probable prognostic factors of Acute Viral Hepatitis in pediatric population.Methods: Consecutive patients of suspected Acute Viral Hepatitis, below the age of 15 years, attending the liver clinic between January 2006 and December2010were studied. After clinical examination they were subjected to blood tests and ultrasound examination of abdomen. The patients were divided in 3 age groups; 0–5, 5–10 and 5–15 years. Clinical features, laboratory parameters, ultrasound findings were compared in three age groups.Results: Etiology of Acute Viral Hepatitis was Hepatitis A virus 266 (85%), Hepatitis E virus in 24 (8%), Hepatitis B virus in 15 (5%). In 7(2%) patients etiology was unknown. Three patients went to acute liver failure but improved with conservative treatment. There was no statistical difference in most of the parameters studied in different age groups. Ascites was more common in 5-10 years age group. Patients with secondary bacterial infection, ultrasound evidence of prominent biliary tree and ascites were associated with increased duration of illness. Patients with history of herbal medications had prolonged cholestasis.Conclusions: Hepatitis A is most common cause of Acute Viral Hepatitis in pediatric population. Improper use of herbal medications, secondary bacterial infection and faulty dietary intake was associated with prolonged illness. Patients with prominent biliary radicals should be treated with antibiotics even with normal blood counts for earlier recovery.Keywords: Acute viral hepatitis; hepatitis A; hepatitis E; herbal medications.

scholarly journals Analysis Of Clinical, Haematological And Biochemical Parameters In Patients With Infectious Mononucleosis

2015 ◽  
Vol 16 (4) ◽  
pp. 291-295
Author(s):  
Petar Canović ◽  
Aleksandra Vranic ◽  
Sara Petrovic ◽  
Ivana Rakovic ◽  
Biljana Popovska Jovicic ◽  
...  
Keyword(s):  
Infectious Mononucleosis ◽  
Primary Infection ◽  
Clinical Symptoms ◽  
Mean Value ◽  
Clinical Feature ◽  
Laboratory Parameters ◽  
Barr Virus ◽  
Clinical Center ◽  
Epstein Barr ◽  
Normal Leukocyte

AbstractPrimary infection with Epstein-Barr virus (EBV) usually occurs in early childhood and often does not present clinical symptoms. More than 90% of adults are infected with this virus. A primary infection that occurs in adolescence or adulthood is usually clinically presented as infectious mononucleosis with a triad of symptoms: fever, lymphadenopathy and pharyngitis. Our retrospective study included 51 patients with a median age of 17 (9-23) years and serologically confirmed infectious mononucleosis. All patients with infectious mononucleosis were treated at the Clinic for Infectious Diseases at the Clinical Center in Kragujevac during 2013. We analysed the clinical, haematological and laboratory parameters of patients. The aspartate-aminotransferase levels were increased in 40 patients, with a mean value of 116.24 (±93.22); the alanine-aminotransferase levels were increased in 44 patients, with a mean value of 189.24 (±196.69). Lymphadenopathy was the most common clinical feature upon admission in 49 patients (96%); 38 patients (74.5%) had splenomegaly, and 20 (39%) had hepatomegaly. Twenty-six patients (51%) had leukocytosis with lymphocytosis, while 15 (75%) of the 20 who had a normal leukocyte count also had lymphocytosis. In the present study, we updated the clinical, haematological and laboratory parameters, which may lead to the establishment of an accurate diagnosis and promote further treatment of the patients.

scholarly journals A Case of Acute Hepatitis E Complicated by Acute Pancreatitis in Eastern India

2020 ◽  
Vol 12 (2) ◽  
Author(s):  
Rudrajit P ◽  
Shubhabrata D ◽  
Sourav P ◽  
Partha SC ◽  
Jayati M ◽  
...  
Keyword(s):  
Acute Pancreatitis ◽  
Abdominal Pain ◽  
Acute Hepatitis ◽  
Viral Hepatitis ◽  
Hepatitis A ◽  
Young Male ◽  
Hepatitis E ◽  
Uneventful Recovery ◽  
Eastern India ◽  
Acute Hepatitis E

Viral hepatitis may be occasionally associated with acute pancreatitis. Usually the patient presents with abdominal pain in the second or third week of illness. Hepatitis A or E viruses are mostly implicated. HEV related acute pancreatitis was first reported only 12 years ago. We report a case of a young male presenting with acute Hepatitis E infection complicated by pancreatitis. He had an uneventful recovery. This is probably the first report of this association from Eastern India.

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