Viral Hepatitis: Retrospective Review in a Canadian Pediatric Hospital

Introduction. Clinical presentation of viral hepatitis ranges from mild symptoms to fulminant hepatitis. Our aim is to describe clinical presentation and outcomes of children with viral hepatitis from the Eastern Ontario/Western Quebec regions of Canada. Methods. Retrospective chart review of children diagnosed with viral hepatitis at our institution from January 1, 1998, to December 31, 2007. Results. There were 261 charts reviewed, only 64 had a confirmed viral etiology: 34 (53%) hepatitis B (HBV), 16 (25%) hepatitis C (HCV), 4 (6.3%) hepatitis A (HAV), 7 (11%) cytomegalovirus (CMV), and 3 (4.7%) Epstein-Barr virus (EBV). Children with HBV presented at a mean age of 6.4±4.6 years. Spontaneous seroconversion (appearance of HBVeAb and loss of HBVeAg) occurred in 21/34 (61.7%). Children with acute hepatitis (HAV, CMV, and EBV) presented with mild abdominal pain, jaundice, and fevers. Overall outcome was excellent. Conclusion. Acute and chronic hepatitis in children has a benign course; moreover, HBV spontaneous seroconversion is common in pediatric patients.

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Early Detection of Nasopharyngeal Carcinoma

International Journal of Otolaryngology ◽

10.1155/2011/638058 ◽

2011 ◽

Vol 2011 ◽

pp. 1-6 ◽

Cited By ~ 23

Author(s):

Keiji Tabuchi ◽

Masahiro Nakayama ◽

Bungo Nishimura ◽

Kentaro Hayashi ◽

Akira Hara

Keyword(s):

Nasopharyngeal Carcinoma ◽

Early Detection ◽

Epstein Barr Virus ◽

Clinical Presentation ◽

Southern China ◽

Squamous Cell Carcinomas ◽

Treatment Results ◽

Barr Virus ◽

Associated Malignancy ◽

Epstein Barr

Nasopharyngeal carcinoma (NPC) is a unique disease with a clinical presentation, epidemiology, and histopathology differing from other squamous cell carcinomas of the head and neck. NPC is an Epstein-Barr virus-associated malignancy with a marked racial and geographic distribution. Specifically, it is highly prevalent in southern China, Southeast Asia, and the Middle East. To date, most NPC patients have been diagnosed in the advanced stage, but the treatment results for advanced NPC are not satisfactory. This paper provides a brief overview regarding NPC, with the focus on the early detection of initial and recurrent NPC lesions.

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Non-hodgkin's lymphomas in patients with human immunodeficiency virus infection. Presence of epstein–barr virus byIn situ hybridization, clinical presentation, and follow-up

Cancer ◽

10.1002/1097-0142(19911201)68:11<2460::aid-cncr2820681123>3.0.co;2-0 ◽

1991 ◽

Vol 68 (11) ◽

pp. 2460-2465 ◽

Cited By ~ 24

Author(s):

Jeannette Guarner ◽

Carlos Del Rio ◽

Daniel Carr ◽

Lynn E. Hendrix ◽

J. William Eley ◽

...

Keyword(s):

Human Immunodeficiency Virus ◽

Virus Infection ◽

Human Immunodeficiency Virus Infection ◽

Epstein Barr Virus ◽

Clinical Presentation ◽

Barr Virus ◽

Immunodeficiency Virus ◽

Epstein Barr ◽

Hodgkin's Lymphomas

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Acute pancreatitis and hepatitis: A rare presentation of Epstein–Barr virus

Case Reports International ◽

10.5348/100092z06sr2021cr ◽

2021 ◽

Vol 10 ◽

pp. 1

Author(s):

Sathishkumar Ramalingam ◽

Maheswari Muruganandam ◽

Harkesh Arora ◽

Kulothungan Gunasekaran ◽

Priyesh Padmanabhan

Keyword(s):

Acute Pancreatitis ◽

Epstein Barr Virus ◽

Hepatitis A ◽

Rare Presentation ◽

Barr Virus ◽

Epstein Barr

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Diagnostic dilemmas in Epstein-Barr virus hepatitis mimicking autoimmune hepatitis: A case report

Journal of Family Medicine and Primary Care ◽

10.4103/jfmpc.jfmpc_98_20 ◽

2020 ◽

Vol 9 (5) ◽

pp. 2502

Author(s):

Ekta Gupta ◽

Krithiga Ramachandran ◽

Reshu Agarwal ◽

Chhagan Bihari ◽

Vikram Bhatia

Keyword(s):

Case Report ◽

Autoimmune Hepatitis ◽

Epstein Barr Virus ◽

Hepatitis A ◽

Virus Hepatitis ◽

Barr Virus ◽

Epstein Barr

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Bahaya Penyakit Hepatitis Terhadap Ibu Hamil

10.31219/osf.io/g7pur ◽

2020 ◽

Author(s):

listiana tri widiya puspita sari

Keyword(s):

Epstein Barr Virus ◽

Hepatitis A ◽

Hepatitis Virus ◽

Hepatitis E ◽

Mumps Virus ◽

Hepatitis D ◽

Barr Virus ◽

Acute Yellow Atrophy ◽

Acute Fatty Liver ◽

Epstein Barr

Penyakit Hepatitis adalah peradangan pada hati karena toxin, seperti kimia, obat atau agen penyebab infeksi. Penyakit ini disebabkan oleh beberapa jenis virus yang menyerang dan menyebabkan peradangan serta merusak sel-sel organ hati manusia. Hepatitis yang berlangsung kurang dari 6 bulan disebut hepatitis akut, hepatitis yang berlangsung lebih dari 6 bulan disebut hepatitis kronis. Hepatitis diketegorikan dalam beberapa golongan, diantaranya hepatitis A, hepatitis B, hepatitis C, hepatitis D, hepatitis E, dan hepatitis G. Hepatitis juga terjadi karena infeksi virus lainnya, seperti mononukleosis itinfeksiosa, demam kuning dan infeksi Virus Mumps, Virus Rubella, Virus Cytomegalovirus, Virus Epstein-Barr, Virus Herpes. Penyebab hepatitis non – virus yang utama adalah alkohol dan obat-obatan. Pada wanita hamil kemungkinan untuk terjangkit hepatitis virus adalah sama dengan wanita tidak hamil pada umur yang sama. Kelainan hepar yang mempunyai hubungan langsung dengan peristiwa kehamilan, ialah : Acute fatty liver of pregnancy (Obstetric acute yellow-atrophy). Infeksi hepatitis virus pada kehamilan tidak berhubungan langsung dengan peristiwa kehamilan, namun tetap memerlukan penanganan khusus, mengingat penyulit-penyulit yang mungkin timbul baik untuk ibu maupun janin. Hepatitis virus sering menimbulakan jaundice pada kehamilan, dengan kemajuan pengobatan saat ini, asam ursodeoxychalic dapat mengurangi kerusakan hati, baik akut maupun kronik.

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Comparison of clinical and laboratory characteristics of viral hepatitis A and E in Montenegro

Medicinski pregled ◽

10.2298/mpns1004175t ◽

2010 ◽

Vol 63 (3-4) ◽

pp. 175-178

Author(s):

Dragica Terzic ◽

Gordana Mijovic ◽

Brankica Dupanovic ◽

Nenad Draskovic ◽

Neda Svirtlih

Keyword(s):

Viral Hepatitis ◽

Hepatitis A ◽

Liver Function Tests ◽

Hepatitis E ◽

Mean Value ◽

Laboratory Parameters ◽

Barr Virus ◽

Route Of Transmission ◽

Epstein Barr ◽

Commercial Kits

Introduction Hepatitis E has many similarities in with hepatitis A concerning clinical picture, route of transmission and nonexistence of chronicity. Comparison of clinical and laboratory parameters of patients with hepatitis A and E to estimate characteristics of these diseases. Material and methods Total of 54 patients divided into two groups was investigated: 27 had hepatitis A, others had hepatitis E. Detailed history past, clinical examination, liver function tests and ultrasonography of the upper abdomen, were done in all patients. Etiology of viral hepatitis was investigated serologically by enzyme immunoassay (ELISA) using commercial kits for following viruses: Hepatitis A-E viruses, cytomegalovirus, and Epstein-Barr virus. Results Asymptomatic infections (29.6%) and clinical forms without jaundice (59.3%) were more frequent in patients with hepatitis E. Splenomegaly was found more frequent in patients with hepatitis A than in hepatitis E (66.7% vs. 33.3%). Patients with hepatitis E had significantly lower activity of aminotransferases than patients with hepatitis A. A significant increase of gamma-glutamyltranspeptidase was found in patients with hepatitis E (mean value: 120 IU/L). Discussion Our results are in concordance with other reports that hepatitis E virus infection is more common asymptomatic disease than hepatitis A. In addition, hepatocyte necrosis in hepatitis E is less extensive than in hepatitis A measured by the activity of aminotransferases. Contrary to that the value of gamma-glutamyltranspeptidase is more increased in hepatitis E than in hepatitis A without exact explanation uso far. Conclusion Viral hepatitis E and A have differences in some clinical features and laboratory parameters although both diseases principally have resolved without consequences after 6-8 weeks.

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