scholarly journals Selection of air filters for residential fresh air in china based on the control of PM2.5

2021 ◽  
pp. 120-120
Author(s):  
Xin Zhang ◽  
Yuesheng Fan ◽  
Jiaxin Zhang ◽  
Huan Wang ◽  
Shuxuan Wei ◽  
...  
Keyword(s):  
Indoor Air ◽  
Selection Criterion ◽  
Performance Testing ◽  
Economic Cost ◽  
Mass Balance Equation ◽  
Filter Materials ◽  
Optimal Section ◽  
Set Up ◽  
Selection Of ◽  
Pm2.5 Concentration

Efficient filtration provides a healthy and comfortable residential environment. Based on the performance testing for filter materials commonly used in China, the mass balance equation of controlling the indoor PM2.5 concentration was set up, and the filter selection criterion was discussed. An optimal section was suggested by taking into account the economic cost, filter price, and indoor air quality.

Platelet Anti-Aggregating Activity and Tolerance of Clopidogrel in Atherosclerotic Patients

1996 ◽  
Vol 76 (06) ◽  
pp. 0939-0943 ◽  
Author(s):  
B Boneu ◽  
G Destelle ◽  
Keyword(s):  
Platelet Aggregation ◽  
Large Scale ◽  
Bleeding Time ◽  
Antithrombotic Activity ◽  
Ambulatory Patients ◽  
Patients At Risk ◽  
Set Up ◽  
Ischemic Events ◽  
Large Scale Clinical Trial ◽  
Selection Of

SummaryThe anti-aggregating activity of five rising doses of clopidogrel has been compared to that of ticlopidine in atherosclerotic patients. The aim of this study was to determine the dose of clopidogrel which should be tested in a large scale clinical trial of secondary prevention of ischemic events in patients suffering from vascular manifestations of atherosclerosis [CAPRIE (Clopidogrel vs Aspirin in Patients at Risk of Ischemic Events) trial]. A multicenter study involving 9 haematological laboratories and 29 clinical centers was set up. One hundred and fifty ambulatory patients were randomized into one of the seven following groups: clopidogrel at doses of 10, 25, 50,75 or 100 mg OD, ticlopidine 250 mg BID or placebo. ADP and collagen-induced platelet aggregation tests were performed before starting treatment and after 7 and 28 days. Bleeding time was performed on days 0 and 28. Patients were seen on days 0, 7 and 28 to check the clinical and biological tolerability of the treatment. Clopidogrel exerted a dose-related inhibition of ADP-induced platelet aggregation and bleeding time prolongation. In the presence of ADP (5 \lM) this inhibition ranged between 29% and 44% in comparison to pretreatment values. The bleeding times were prolonged by 1.5 to 1.7 times. These effects were non significantly different from those produced by ticlopidine. The clinical tolerability was good or fair in 97.5% of the patients. No haematological adverse events were recorded. These results allowed the selection of 75 mg once a day to evaluate and compare the antithrombotic activity of clopidogrel to that of aspirin in the CAPRIE trial.

STUDY OF INACCURACY IN THE OPERATION OF THE MAIN CONTROLLER OF STB MACHINE

2019 ◽  
Keyword(s):  
Normal Distribution ◽  
Stable Process ◽  
Random Errors ◽  
Actual Length ◽  
Experimental Data Processing ◽  
Set Up ◽  
Main Regulator ◽  
Transmission Gear ◽  
Selection Of

At production of fabrics, including fabrics for agricultural purpose, an important role is played by the cor-rect adjustment of operation of machine main regulator. The quality of setup of machine main controller is determined by the proper selection of rotation angle of warp beam weaving per one filling thread. In the pro-cess of using the regulator as a result of mistakes in adjustment, wear of transmission gear and backlashes in connections of details there are random changes in threads length. The purpose of the article is the research of property of random errors of basis giving by STB machine regulator. Mistakes can be both negative, and positive. In case of emergence only negative or only positive mistakes operation of the machine becomes im-possible as there will be a consecutive accumulation of mistakes. As a result of experimental data processing for stable process of weaving and the invariable diameter of basis threads winding of threads it is revealed that the random error of giving is set up as linear function of the accidental length having normal distribution. Measurements of accidental deviations in giving of a basis by the main regulator allowed to construct a curve of normal distribution of its actual length for one pass of weft thread. The presented curve of distribution of random errors in giving of a basis is the displaced curve of normal distribution of the accidental sizes. Also we define the density of probability of normal distribution of basis giving errors connected with a margin er-ror operation of the main regulator knowing of which allows to plan ways of their decrease that is important for improvement of quality of the produced fabrics.

Discovery of five new Galactic symbiotic stars in the VPHAS+ survey

2021 ◽  
Vol 502 (2) ◽  
pp. 2513-2517
Author(s):  
Stavros Akras ◽  
Denise R Gonçalves ◽  
Alvaro Alvarez-Candal ◽  
Claudio B Pereira
Keyword(s):  
Spectroscopic Data ◽  
Selection Criterion ◽  
Optical Spectra ◽  
Emission Lines ◽  
High Rate ◽  
Symbiotic Stars ◽  
Selection Of

ABSTRACT We report the validation of a recently proposed infrared (IR) selection criterion for symbiotic stars (SySts). Spectroscopic data were obtained for seven candidates, selected from the SySt candidates of Akras et al. by employing the new supplementary IR selection criterion for SySts in the VST/OmegaCAM Photometric H-Alpha Survey. Five of them turned out to be genuine SySts after the detection of H α, He ii, and [O iii] emission lines as well as TiO molecular bands. The characteristic O vi Raman-scattered line is also detected in one of these SySts. According to their IR colours and optical spectra, all five newly discovered SySts are classified as S-type. The high rate of true SySts detections of this work demonstrates that the combination of the H α emission and the new IR criterion improves the selection of target lists for follow-up observations by minimizing the number of contaminants and optimizing the observing time.

scholarly journals Exposure and Health Impacts Related to Outdoor and Indoor Air Pollutants

Atmosphere ◽  
2021 ◽  
Vol 12 (1) ◽  
pp. 105
Author(s):  
Haider A. Khwaja
Keyword(s):  
Indoor Air ◽  
Air Pollutants ◽  
Health Impacts ◽  
Special Issue ◽  
Indoor Air Pollutants ◽  
Selection Of

The five papers included in this Special Issue represent a diverse selection of contributions [...]

scholarly journals Can Public Spaces Effectively Be Used as Cleaner Indoor Air Shelters during Extreme Smoke Events?

2021 ◽  
Vol 18 (8) ◽  
pp. 4085
Author(s):  
Amanda J. Wheeler ◽  
Ryan W. Allen ◽  
Kerryn Lawrence ◽  
Christopher T. Roulston ◽  
Jennifer Powell ◽  
...  
Keyword(s):  
Air Quality ◽  
Indoor Air ◽  
Air Conditioning ◽  
High Efficiency ◽  
Public Library ◽  
Public Building ◽  
Central Air Conditioning ◽  
The Media ◽  
The Impact ◽  
Pm2.5 Concentration

During extreme air pollution events, such as bushfires, public health agencies often recommend that vulnerable individuals visit a nearby public building with central air conditioning to reduce their exposure to smoke. However, there is limited evidence that these “cleaner indoor air shelters” reduce exposure or health risks. We quantified the impact of a “cleaner indoor air shelter” in a public library in Port Macquarie, NSW, Australia when concentrations of fine particulate matter (PM2.5) were elevated during a local peat fire and nearby bushfires. Specifically, we evaluated the air quality improvements with central air conditioning only and with the use of portable high efficiency particulate air (HEPA) filter air cleaners. We measured PM2.5 from August 2019 until February 2020 by deploying pairs of low-cost PM2.5 sensors (i) inside the main library, (ii) in a smaller media room inside the library, (iii) outside the library, and (iv) co-located with regulatory monitors located in the town. We operated two HEPA cleaners in the media room from August until October 2019. We quantified the infiltration efficiency of outdoor PM2.5 concentrations, defined as the fraction of the outdoor PM2.5 concentration that penetrates indoors and remains suspended, as well as the additional effect of HEPA cleaners on PM2.5 concentrations. The infiltration efficiency of outdoor PM2.5 into the air-conditioned main library was 30%, meaning that compared to the PM2.5 concentration outdoors, the concentrations of outdoor-generated PM2.5 indoors were reduced by 70%. In the media room, when the HEPA cleaners were operating, PM2.5 concentrations were reduced further with a PM2.5 infiltration efficiency of 17%. A carefully selected air-conditioned public building could be used as a cleaner indoor air shelter during episodes of elevated smoke emissions. Further improvements in indoor air quality within the building can be achieved by operating appropriately sized HEPA cleaners.

scholarly journals Improved selection of participants in genetic longevity studies: family scores revisited

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Mar Rodríguez-Girondo ◽  
Niels van den Berg ◽  
Michel H. Hof ◽  
Marian Beekman ◽  
Eline Slagboom
Keyword(s):  
Missing Data ◽  
The Netherlands ◽  
Family Size ◽  
Simulation Study ◽  
Missing Values ◽  
Selection Criterion ◽  
Limited Success ◽  
Main Challenge ◽  
Historical Sample ◽  
Selection Of

Abstract Background Although human longevity tends to cluster within families, genetic studies on longevity have had limited success in identifying longevity loci. One of the main causes of this limited success is the selection of participants. Studies generally include sporadically long-lived individuals, i.e. individuals with the longevity phenotype but without a genetic predisposition for longevity. The inclusion of these individuals causes phenotype heterogeneity which results in power reduction and bias. A way to avoid sporadically long-lived individuals and reduce sample heterogeneity is to include family history of longevity as selection criterion using a longevity family score. A main challenge when developing family scores are the large differences in family size, because of real differences in sibship sizes or because of missing data. Methods We discussed the statistical properties of two existing longevity family scores: the Family Longevity Selection Score (FLoSS) and the Longevity Relatives Count (LRC) score and we evaluated their performance dealing with differential family size. We proposed a new longevity family score, the mLRC score, an extension of the LRC based on random effects modeling, which is robust for family size and missing values. The performance of the new mLRC as selection tool was evaluated in an intensive simulation study and illustrated in a large real dataset, the Historical Sample of the Netherlands (HSN). Results Empirical scores such as the FLOSS and LRC cannot properly deal with differential family size and missing data. Our simulation study showed that mLRC is not affected by family size and provides more accurate selections of long-lived families. The analysis of 1105 sibships of the Historical Sample of the Netherlands showed that the selection of long-lived individuals based on the mLRC score predicts excess survival in the validation set better than the selection based on the LRC score . Conclusions Model-based score systems such as the mLRC score help to reduce heterogeneity in the selection of long-lived families. The power of future studies into the genetics of longevity can likely be improved and their bias reduced, by selecting long-lived cases using the mLRC.

GIS Based Multi-Criteria decision support system and machine learning for Hospital Site Selection case study Oran - Algeria

2022 ◽  
Vol 14 (1) ◽  
pp. 0-0
Keyword(s):  
Site Selection ◽  
Decision Makers ◽  
Analysis Method ◽  
Automatic Learning ◽  
Hospital Site ◽  
Set Up ◽  
High Level ◽  
Selection Of ◽  
The Ideal

The selection of hospital sites is one of the most important choice a decision maker has to take so as to resist the pandemic. The decision may considerably affect the outbreak transmission in terms of efficiency , budget, etc. The main targeted objective of this study is to find the ideal location where to set up a hospital in the willaya of Oran Alg. For this reason, we have used a geographic information system coupled to the multi-criteria analysis method AHP in order to evaluate diverse criteria of physiological positioning , environmental and economical. Another objective of this study is to evaluate the advanced techniques of the automatic learning . the method of the random forest (RF) for the patterning of the hospital site selection in the willaya of Oran. The result of our study may be useful to decision makers to know the suitability of the sites as it provides a high level of confidence and consequently accelerate the power to control the COVID19 pandemic.

A Skywave OTHR Adaptive Frequency Selection Method Based on Preliminary Criterion and Weighted Criterion

2014 ◽  
Vol 1061-1062 ◽  
pp. 974-977
Author(s):  
Shi Hua Liu ◽  
Xian Gang Liu ◽  
Zhi Jian Sun
Keyword(s):  
Selection Criterion ◽  
Selection Method ◽  
Frequency Selection ◽  
Selection Of

A skywave radar adaptive frequency selection method based on the preliminary criterion and the weighted criterion is presented. In this method, according to the various operational tasks, the frequency selection criterion is divided into the preliminary criterion and the weighted criterion based on the characteristic of the targets. The adaptive frequency selection of the skywave radar is achieved by the weighted computed of the frequency selection criterion. The feasibility and availability is demonstrated by an example.

A New Approach to Drug Discovery

2012 ◽  
Vol 17 (4) ◽  
pp. 542-549 ◽  
Author(s):  
Maria Cândida Monteiro ◽  
Mercedes de la Cruz ◽  
Juan Cantizani ◽  
Catalina Moreno ◽  
José R. Tormo ◽  
...  
Keyword(s):  
Drug Discovery ◽  
Antifungal Activity ◽  
High Throughput Screening ◽  
Low Cost ◽  
Pharmacological Action ◽  
Natural Extracts ◽  
Microbial Extracts ◽  
Set Up ◽  
Microtiter Assay ◽  
Selection Of

Natural products are an inexhaustible source for drug discovery. However, the validation and selection of primary screening assays are vital to guarantee a selection of extracts or molecules with relevant pharmacological action and worthy of following up. The assay must be rapid, simple, easy to implement, and produce quick results and preferably at a low cost. In this work, we developed and validated a colorimetric microtiter assay using the resazurin viability dye. The parameters of the resazurin method for high-throughput screening (HTS) using natural extracts against Aspergillus fumigatus were optimized and set up. The extracts plus RPMI-1640 modified medium containing the spores and 0.002% resazurin were added per well. The fluorescence was read after 24 to 30 h of incubation. The resazurin proved to be as suitable as Alamar Blue for determining the minimal inhibitory concentration of different antifungals against A. fumigatus and effective to analyze fungicidal and fungistatic compounds. An HTS of 12 000 microbial extracts was carried out against two A. fumigatus strains, and 2.7% of the extracts displayed antifungal activity. Our group has been the first to use this methodology for screening a collection of natural extracts to identify compounds with antifungal activity against the medically important human pathogen A. fumigatus.

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