Depletion of CD4 + and CD8 + T Lymphocyte Subpopulations by CIA-1, a Chicken Infectious Anemia Virus

1993 ◽  
Vol 37 (2) ◽  
pp. 492 ◽  
Author(s):  
Liang-biao Hu ◽  
Benjamin Lucio ◽  
Karel A. Schat
2015 ◽  
Vol 110 (5) ◽  
pp. 596-605 ◽  
Author(s):  
Raquel Ferraz ◽  
Clarissa Ferreira Cunha ◽  
Maria Inês Pimentel ◽  
Marcelo Rosandiski Lyra ◽  
Armando Oliveira Schubach ◽  
...  

2004 ◽  
Vol 98 (1) ◽  
pp. 57-65 ◽  
Author(s):  
Nikolaos Tzanakis ◽  
Georgios Chrysofakis ◽  
Maria Tsoumakidou ◽  
Despina Kyriakou ◽  
Joanna Tsiligianni ◽  
...  

Author(s):  
Meng-yun Li ◽  
Luo liu ◽  
Fu Zhang ◽  
Xue-min Zhu ◽  
Li-fang Si ◽  
...  

Background: 6-furfuryloaminopurine (KT) is the first compound to be identified as a cytokinin. Despite that there are many studies related to KT but the mechanism of KT in resisting immunosenescence remains unclear. The objective of this study is to investigate the influences of KT on the immunity of thymus in rats by detecting the apoptosis and the proliferation index (PI).Methods: We firstly established an aging rat model by subcutaneously injecting D- galactose (D-gal, 125mg/kg•BW) in the dorsal neck of Sprague Daly rats (SD rats); then the rats were divided into KT treatment groups (three groups for different doses of KT), aging model group (without KT treatment) and young control group. The rats in KT treatment groups were treated with different-dose KT and the key indices including the changes of the number of CD3+, CD4+ and CD8+ T lymphocyte subpopulations in peripheral blood, the apoptosis of thymus lymphocytes. Result: KT could increase the number of the peripheral CD3+, CD4+ and CD8+ T lymphocytes of the aging rats while decreased the apoptotic rate of thymocytes and increased PI Index.


2008 ◽  
Vol 6 (2) ◽  
pp. 196-208
Author(s):  
Moshira, A. El-abasy ◽  
Gamal, R. Hassab El-nabby ◽  
Ahmed, S. Hegasy ◽  
Salwa, M. Helmy

Animals ◽  
2021 ◽  
Vol 11 (4) ◽  
pp. 944
Author(s):  
Giulia Quaglia ◽  
Giulia Mescolini ◽  
Elena Catelli ◽  
Giacomo Berto ◽  
Filippo Muccioli ◽  
...  

Chicken infectious anemia virus (CIAV) is a pathogen of chickens associated with immunosuppression and with a disease named chicken infectious anemia. The present survey reports an epidemiological study on CIAV distribution in Italian broiler, broiler breeder and backyard chicken flocks. Twenty-five strains were detected by a specifically developed nested PCR protocol, and molecularly characterized by partial VP1 gene or complete genome sequencing. Viral DNA amplification was successfully obtained from non-invasive samples such as feathers and environmental dust. Sequence and phylogenetic analysis showed the circulation of field or potentially vaccine-derived strains with heterogeneous sequences clustered into genogroups II, IIIa, and IIIb. Marker genome positions, reported to be correlated with CIAV virulence, were evaluated in field strains. In conclusion, this is the first survey focused on the molecular characteristics of Italian CIAVs, which have proved to be highly heterogeneous, implementing at the same time a distribution map of field viruses worldwide.


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