The Living Body Series: Nerves at Work

1988 ◽  
Vol 88 (8) ◽  
pp. 1145
Author(s):  
Judy Tyler
Keyword(s):  
Living Body

Non-Cottrell Behavior of the Dopamine Redox Reaction Observed on the Carbon Fibre Microelectrode by the Double-Step Voltcoulometry

2004 ◽  
Vol 69 (2) ◽  
pp. 419-425 ◽  
Author(s):  
Katarína Gmucová ◽  
Jozef Orlický ◽  
Juraj Pavlásek
Keyword(s):  
Carbon Fibre ◽  
Redox Reaction ◽  
Measured Data ◽  
The Other ◽  
Diffusion Current ◽  
Double Step ◽  
Dopamine Concentration ◽  
Living Body ◽  
Carbon Fibre Microelectrode ◽  
Experimental Errors

The redox reaction of the neurotransmitter dopamine at the carbon fibre microelectrode was studied by several electrochemical methods. It was found that under conditions usual in a living body, the diffusion current fullfils, within experimental errors, the behavior theoretically predicted by the Cottrell equation. Nevertheless, attention should be paid to the fact that unsupported or weakly supported conditions give rise to a non-Cottrell response of diffusion current. Moreover, similar changes were observed if the dopamine concentration was either lower such as several units of μmol l-1, or about 100 μmol l-1 or higher. The non-Cottrell behavior of diffusion current involves the nonlinearity of the dopamine calibration curve obtained by pulse techniques. The present work is aimed at pointing out that such behavior of the measured data could lead to misinterpretation of the obtained dopamine concentration. Similar features could be also achieved for the other catecholamines.

scholarly journals Melanogenesis Connection with Innate Immunity and Toll-Like Receptors

2020 ◽  
Vol 21 (24) ◽  
pp. 9769
Author(s):  
Saaya Koike ◽  
Kenshi Yamasaki
Keyword(s):  
Skin Pigmentation ◽  
Innate Immune ◽  
Mitogen Activated Protein Kinase ◽  
Ultraviolet Rays ◽  
Toll Like Receptors ◽  
Pigment Formation ◽  
Living Body ◽  
Pigmentary Disorders ◽  
Wide Range ◽  
Griscelli Syndrome

The epidermis is located in the outermost layer of the living body and is the place where external stimuli such as ultraviolet rays and microorganisms first come into contact. Melanocytes and melanin play a wide range of roles such as adsorption of metals, thermoregulation, and protection from foreign enemies by camouflage. Pigmentary disorders are observed in diseases associated with immunodeficiency such as Griscelli syndrome, indicating molecular sharing between immune systems and the machineries of pigment formation. Melanocytes express functional toll-like receptors (TLRs), and innate immune stimulation via TLRs affects melanin synthesis and melanosome transport to modulate skin pigmentation. TLR2 enhances melanogenetic gene expression to augment melanogenesis. In contrast, TLR3 increases melanosome transport to transfer to keratinocytes through Rab27A, the responsible molecule of Griscelli syndrome. TLR4 and TLR9 enhance tyrosinase expression and melanogenesis through p38 MAPK (mitogen-activated protein kinase) and NFκB signaling pathway, respectively. TLR7 suppresses microphthalmia-associated transcription factor (MITF), and MITF reduction leads to melanocyte apoptosis. Accumulating knowledge of the TLRs function of melanocytes has enlightened the link between melanogenesis and innate immune system.

scholarly journals On the transcendental undercurrents of phenomenology: the case of the living body

2021 ◽  
Author(s):  
Sara Heinämaa
Keyword(s):  
Lived Body ◽  
Living Body ◽  
Special Scientific ◽  
Mutual Relations ◽  
Scientific Debates

AbstractToday the phenomenological concept of the lived body figures centrally in several philosophical and special scientific debates. In these wide and widening fields, the concept is used with multiple different meanings. In order to clarify and delineate the debates, this paper provides an explication of the phenomenological-transcendental methods. It argues that these methods help us remove the most fundamental ambiguities of the concept of embodiment by distinguishing between the main constituents of the lived body and by illuminating their mutual relations.

scholarly journals Surface Reformation of Medical Devices with DLC Coating

Materials ◽  
2021 ◽  
Vol 14 (2) ◽  
pp. 376
Author(s):  
Mao Kaneko ◽  
Masanori Hiratsuka ◽  
Ali Alanazi ◽  
Hideki Nakamori ◽  
Kazushige Namiki ◽  
...  
Keyword(s):  
High Pressure ◽  
Medical Devices ◽  
Diamond Like Carbon ◽  
Steam Sterilization ◽  
Dlc Coatings ◽  
Chrome Plating ◽  
Living Body ◽  
Dlc Coating ◽  
Pressure Steam ◽  
Adhesion Friction

We evaluated the adhesion, friction characteristics, durability against bodily acids, sterilization, cleaning, and anti-reflection performance of diamond-like carbon (DLC) coatings formed as a surface treatment of intracorporeal medical devices. The major coefficients of friction during intubation in a living body in all environments were lower with DLC coatings than with black chrome plating. DLC demonstrated an adhesion of approximately 24 N, which is eight times stronger than that of black chrome plating. DLC-coated samples also showed significant stability without being damaged during acid immersion and high-pressure steam sterilization, as suggested by the results of durability tests. In addition, the coatings remained unpeeled in a usage environment, and there was no change in the anti-reflection performance of the DLC coatings. In summary, DLC coatings are useful for improving intracorporeal device surfaces and extending the lives of medical devices.

scholarly journals Food to suppress senile change of a living body.

1987 ◽  
Vol 25 (5) ◽  
pp. 336-340
Author(s):  
SETSURO MATSUSHITA
Keyword(s):  
Living Body

Experimental Evaluation of Estimating Living-Body Direction Using Array Antenna for Multipath Environment

2014 ◽  
Vol 13 ◽  
pp. 718-721 ◽  
Author(s):  
Keita Konno ◽  
Masaki Nango ◽  
Naoki Honma ◽  
Kentaro Nishimori ◽  
Nobuyasu Takemura ◽  
...  
Keyword(s):  
Experimental Evaluation ◽  
Array Antenna ◽  
Living Body ◽  
Multipath Environment

The Church and the Development of Doctrine

2004 ◽  
Vol 13 (1) ◽  
pp. 57-77 ◽  
Author(s):  
Simon Chan
Keyword(s):  
Holy Spirit ◽  
Special Role ◽  
Healthy Development ◽  
The Public ◽  
Public Square ◽  
Living Body ◽  
Living Tradition ◽  
The Holy Spirit ◽  
Third Person ◽  
The Church

AbstractDoctrines are the authoritative teachings of the Church, yet the modern church is hampered by its inability to speak authoritatively even to its own members on matters of doctrine. One reason is that doctrines are widely perceived as archaic and fixed formulations with little significance for the present day. True doctrines, in fact, are constantly developing as the Church moves towards eschatological fulfillment. Yet for doctrines to develop properly there needs to be a proper ecclesiology. The Church is not an entity that God brought into being to return creation to its original purpose after the Fall; rather, the Church is prior to creation, chosen in Christ before the creation of the world (Eph. 1.4). It is a divine-humanity, ontologically linked to Christ the Head. It is the living Body of Christ, the totus Christus.Within the continuing life of prayer and worship, the Church’s doctrines are re-enacted, renewed and developed. These acts constitute the ecclesial experience or the living tradition. The living tradition is the transmission and development of the gospel of Jesus Christ in the on-going practices of the Church through the power of the Holy Spirit. The coming of the Spirit upon the Church at Pentecost is not just to enable the Church to preach the gospel but to constitute the Church as part of the gospel itself. That is to say, the gospel story includes the story of the Spirit in the Church. The third person of the Godhead is revealed as such in his special relation to the Church. The Church, therefore, could be called the ‘polity of the Spirit’, that is, the public square in which the Spirit is especially at work to bring God’s ultimate purpose to fulfillment. There is, therefore, no separation between ecclesiology and pneumatology. They are necessary for maintaining the living tradition and ensuring the healthy development of doctrine until the Church attains unity of the faith. Pentecostals who see the Pentecost event as the distinctive mark of their identity have a special role to play: by becoming more truly catholic in their ecclesiology, they become more truly Pentecostal. This accords well with their early ecumenical instinct.

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