Neurologic Complications of Cancer

2017 ◽  
Author(s):  
Soma Sengupta ◽  
Eudocia Q Lee ◽  
Patrick Y Wen
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Key Words ◽  
Early Recognition ◽  
Paraneoplastic Syndromes ◽  
Neurologic Complications ◽  
Neurologic Injury ◽  
Key Words Cancer ◽  
Mortality And Morbidity ◽  
Central Nervous System Metastases

Neurologic complications from cancer and its therapies can significantly impact mortality and morbidity. Early recognition and intervention are key to preventing permanent neurologic injury. This review discusses common and uncommon neurologic complications of cancer, including central nervous system metastases, treatment-related neurotoxicities (including immunotherapies), and paraneoplastic syndromes. Workup and management of these neurologic complications are also addressed. Key words: cancer, chemotherapy, metastases, nervous system complications, paraneoplastic syndromes

Neurologic Complications of Cancer

2017 ◽  
Author(s):  
Soma Sengupta ◽  
Eudocia Q Lee ◽  
Patrick Y Wen
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Key Words ◽  
Early Recognition ◽  
Paraneoplastic Syndromes ◽  
Neurologic Complications ◽  
Neurologic Injury ◽  
Key Words Cancer ◽  
Mortality And Morbidity ◽  
Central Nervous System Metastases

Neurologic complications from cancer and its therapies can significantly impact mortality and morbidity. Early recognition and intervention are key to preventing permanent neurologic injury. This review discusses common and uncommon neurologic complications of cancer, including central nervous system metastases, treatment-related neurotoxicities (including immunotherapies), and paraneoplastic syndromes. Workup and management of these neurologic complications are also addressed. Key words: cancer, chemotherapy, metastases, nervous system complications, paraneoplastic syndromes

scholarly journals Tuberculoma of Central Nervous System with Right Sided Hemiparesis

2015 ◽  
Vol 14 (1) ◽  
pp. 74-76
Author(s):  
Shahed Iqbal ◽  
Wahida Akter ◽  
M Badruddoza ◽  
Mahmood Ahmed Chowdhury
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Cranial Nerve ◽  
Cranial Nerve Palsy ◽  
Nerve Palsy ◽  
Early Recognition ◽  
Surrounding Tissue ◽  
High Grade Fever ◽  
Mortality And Morbidity ◽  
The Brain

Tuberculoma is one of the manifestations of Central Nervous System (CNS) tuberculosis (TB). A tuberculoma is a tuberculous focus, which enlarges with in brain tissue, firm, avascular, spherical masses, with size varying between 2 cm to 10 cm in diameter and the compressed surrounding tissue shows edema and gliosis. Tuberculoma resuls from aggregation of caseous tubercle that usually manifest clinically as brain tumour. Tuberculomas account for upto 40% of brain tumours in some areas of the world. In adults tuberculomas are most often supratentorial, but in children they are often infratentorial, located at the base of the brain near the cerebellum. Lesions are most often singular but may be multiple. The most common symptoms are headache, fever & convulsion & also may give rise to signs of raised intracranial pressure or a hemiplegia, or cranial nerve palsy if in the brain stem. Here described a case of 4 years old female child who presented with the complants of high grade fever for 10 days duration followed by right sided weakness for 4 months. She had 6,sup>th and 7th cranial nerve palsy with exaggerated reflex on right side. Her tuberculin test was positive but Cerebro Spinal Fluid (CSF) study was normal & Magnetic Resonance Imaging (MRI) of brain showed rim enhancing lesion. Early recognition and timely treatment of CNS TB is critical if the considerable mortality and morbidity associated with the condition is to be prevented. DOI: http://dx.doi.org/10.3329/cmoshmcj.v14i1.22892 Chatt Maa Shi Hosp Med Coll J; Vol.14 (1); Jan 2015; Page 74-76

Central Nervous System Metastases from Primary Epithelial Ovarian Cancer

2003 ◽  
Vol 10 (3) ◽  
pp. 244-253 ◽  
Author(s):  
Lalit Kumar ◽  
Suchitra Barge ◽  
Ashok K. Mahapatra ◽  
Sanjay Thulkar ◽  
Gaura Kishore Rath ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Central Nervous System ◽  
Nervous System ◽  
Epithelial Ovarian Cancer ◽  
Central Nervous System Metastases ◽  
Primary Epithelial Ovarian Cancer

Central nervous system metastases in malignant melanoma

Neurosurgery ◽  
1981 ◽  
Vol 8 (1) ◽  
pp. 26???30 ◽  
Author(s):  
D E Bullard ◽  
E B Cox ◽  
H F Seigler
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Malignant Melanoma ◽  
Central Nervous System Metastases

Neurologic complications in patients with lymphoid cancer

Blood ◽  
2021 ◽  
Author(s):  
Lakshmi Nayak ◽  
Tracy T Batchelor
Keyword(s):  
Nervous System ◽  
Case Studies ◽  
Early Identification ◽  
Vascular Complications ◽  
Paraneoplastic Syndromes ◽  
Neurologic Complications ◽  
Local Spread ◽  
Neurologic Deficits ◽  
Clinical Scenarios ◽  
Oncologic Therapy

Neurologic complications of lymphoid cancer can be challenging to recognize and treat. The nervous system can be affected directly by hematogenous or local spread of lymphoma. Indirect neurologic effects of lymphoma include paraneoplastic syndromes and vascular complications. Lymphoma treatments can also cause neurologic complications. Early identification and treatment are crucial to stabilize or reverse neurologic deficits, prevent further nervous system injury, and to optimize overall oncologic therapy. This article provides an overview of different neurologic complications of lymphoma and its treatments, in addition to presentation of case studies that emphasize commonly encountered clinical scenarios.

CHRONIC LEAD ENCEPHALOPATHY

PEDIATRICS ◽  
1960 ◽  
Vol 25 (2) ◽  
pp. 309-315
Author(s):  
Harry H. White ◽  
Fred D. Fowler
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Pediatric Patients ◽  
Early Recognition ◽  
Central Nervous System Involvement ◽  
Fast Screening ◽  
The Central Nervous System ◽  
Lead Encephalopathy ◽  
Urinary Coproporphyrin

Chronic lead encephalopathy must be considered in the differential diagnosis of pediatric patients who present with manifestations of schizophrenia, behavior disorders or degenerative diseases of the central nervous system. Determination of urinary coproporphyrin is a simple, fast screening procedure applicable to office practice. The prognosis for normal mental development following encephalopathy is poor. It is hoped that early recognition of the more subtle signs of central nervous system involvement will allow treatment to be instituted soon enough to prevent the crippling mental deterioration which is so often a sequela of lead poisoning.

Cerebrospinal fluid β-glucuronidase activities in patients with central nervous system metastases

1985 ◽  
Vol 147 (2) ◽  
pp. 127-134 ◽  
Author(s):  
Anton P. van Zanten ◽  
Albert Twijnstra ◽  
Vrouwkjen van Benthem ◽  
Augustinus A.M. Hart ◽  
Bram W.Ongerboer de Visser
Keyword(s):  
Central Nervous System ◽  
Cerebrospinal Fluid ◽  
Nervous System ◽  
Central Nervous System Metastases

scholarly journals Takotsubo Cardiomyopathy as a Complication/ Sequelae of Prolonged Refractory Seizure: A Case Report from Nepal

2021 ◽  
Author(s):  
Bikash Khadka ◽  
Kishor Khanal
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Intensive Care ◽  
Case Report ◽  
Antiepileptic Drugs ◽  
Takotsubo Cardiomyopathy ◽  
Cardiac Enzymes ◽  
Recurrent Seizure ◽  
Mortality And Morbidity ◽  
Central Nervous System Disorders

Takotsubo cardiomyopathy(TC) is a reversible, yet underdiagnosed cause of mortality and morbidity in the intensive care units. It occurs secondary to sudden catecholamine surge precipitated by any form of emotional or pathological stress. Association between central nervous system disorders and Takotsubo cardiomyopathy is being increasingly reported. Epilepsy is the second most common CNS disorder to trigger TC, SAH being the first. We report a case of TC in an elderly man with prolonged, recurrent seizure episodes refractory to the commonly used antiepileptic drugs (AEDs), who developed unexplained tachycardia, hypotension and elevated cardiac enzymes.

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