Prevalence of VOYAGER PAD trial exclusion criteria in unselected patients undergoing lower limb revascularisation

Author(s):  
Maria A. MOLL ◽  
Daniela ZWERGER ◽  
Kristina J. GRASSL ◽  
Werner WESTREICHER ◽  
Sabrina B. NEURURER ◽  
...  
2014 ◽  
Vol 30 (4) ◽  
pp. 235-241 ◽  
Author(s):  
AZ Nghiem ◽  
N Rudarakanchana ◽  
HM Moore ◽  
AH Davies

Objectives Percutaneous pharmacomechanical thrombectomy is an emerging therapy for acute deep vein thrombosis and may reduce long-term incidence of post-thrombotic syndrome. This study investigates the proportion of patients presenting with lower limb deep vein thrombosis who are potentially suitable for percutaneous pharmacomechanical thrombectomy. Methods A retrospective review of all duplex ultrasound scans for lower limb deep vein thrombosis over two-year period at a regional vascular unit was conducted. All acute occlusive iliofemoral deep vein thrombosis were screened for percutaneous pharmacomechanical thrombectomy suitability according to predefined criteria. Results There were 2513 duplex ultrasound scans for suspected lower limb deep vein thrombosis in the two-year period. There were 120 cases of acute occlusive iliofemoral deep vein thrombosis. After application of inclusion and exclusion criteria 48 out of 120 (40%) patients were identified as potential candidates for percutaneous pharmacomechanical thrombectomy. Conclusions This indicates that a large randomised trial of percutaneous pharmacomechanical thrombectomy is feasible given expected recruitment rates in a multicentre study.


Author(s):  
Arefeh Mokhtari MalekAbadi ◽  
Mohsen Barghamadi ◽  
Amir Ali Jafarnezhadgero

Older adults demonstrate increased amounts of postural sway, which may ultimately lead to falls. The purpose of this systematic review was to investigate the effect of different foot orthoses on lower limb biomechanical variables, lower limb muscular activity, and balance in elderly people. Examining texts based on the search on the Magiran, Google Schoolar, Pubmed, Scopus, and SIVILICA sites were done by using following keywords: foot orthoses, footwear, aging, aged, elderly, Kinematic, walking, loading rate, Kinetic Walking, in combination in four part from 2005 to 2018. In the initial searches, 72 papers were obtained, eight articles based on the inclusion and exclusion criteria were selected. This systematic review demonstrated that the use of textures and modeling orthoses strengthens sensory receptors and improves postures, as well as improves the biomechanical parameters such as evertor and invertor moments and ground reaction forces in some cases.


2019 ◽  
Vol 72 (3) ◽  
pp. 318-322
Author(s):  
Rafał Słoniak ◽  
Tomasz Tittinger ◽  
Damian Szczepański ◽  
Tadeusz Szymon Gaździk ◽  
Małgorzata Kulesa-Mrowiecka ◽  
...  

Introduction: The illustration of the ranges of bending the limb during the outflow allowed to divide the study group into two parts. In the majority of respondents, the initial flexion prevailed over the final one. The researchers focused on finding the reasons for the advantage of the final bend over the initial one in 30% of the subjects. The aim: The analysis of the dynamic stride under the control of the MVN Biomech system in the bending of the knee joint of the lateral limb, comparing the preparation to the leg (initial bending) and its ending (final) Materials and Methods: 18 right-handed 25 to 35 year old runners were selected after the following exclusion criteria were applied: polyarticular hypermobility, systemic diseases, Rheumatoid arthritis, osteoarthritis, post-traumatic instability. The MVN Biomech system assessed the three-dimensional movements of the joints of the free part of the lower limb and pelvis, and the flexibility of the muscles was subject to physiotherapeutic assessment. Results: In 55% of respondents dominated the pattern in which the initial flexion exceeded by min. 10⁰ final bend in both limbs (decreasing type). The researchers focused on finding the reasons for the smaller difference or the advantage of the final bending on both sides in 30% of respondents (mixed type). The comparison of physiotherapeutic examination results and measurements of MVN Biomech showed functional contractures of the tensor fasciae latea muscles in 5 subjects with a mixed type (83% of subjects with a mixed type). Conclusions: Contraction of the tensor fasciae latae constrained the initial flexion of the knee joint of the lateral limb, and also increased bilateral visitation of the hip joints during the dynamic mixed-type twitch. The remaining muscles of the lower limbs show no statistically significant differences in elasticity compared to the type of the leg.


2010 ◽  
Vol 26 (3) ◽  
pp. 94-101 ◽  
Author(s):  
B N Gauci ◽  
J T Powell ◽  
B J Hunt ◽  
J Pilcher ◽  
R Morgan ◽  
...  

Background Deep vein thromboses (DVTs) are a significant cause of morbidity and mortality. Valvular destruction leads to the spectrum of disease called the post-thrombotic syndrome (PTS) with the sequelae of chronic venous ulceration and a reduced quality of life. Catheter-directed thrombolysis (CDT) may reduce the incidence of PTS following an acute proximal DVT and increases quality of life thereafter, but it is uncertain what proportion of patients diagnosed with a DVT would be suitable for CDT. Methods This study quantified the proportion of patients investigated for DVT that would have been suitable for CDT. A retrospective review was performed of all upper and lower limb duplex ultrasound scans for suspected DVTs in a contemporary one-year period in a major regional vascular institute. All positive scans for acute proximal lower limb DVTs were compared against strict inclusion and exclusion criteria for CDT, based on national guidelines and international randomized trials. Results A total of 2368 duplex ultrasound venous investigations were performed in a one-year period and 252 scans demonstrated DVT. Of these, 158 were acute proximal lower limb DVTs. Application of the inclusion and exclusion criteria for CDT suggested that 47/158 (30%) were potentially suitable for CDT using current criteria. The median age of the 158 patients was 58 years, meaning that more than half were of working age and 54% were men. Conclusion Using current eligibility criteria, only about 30% of patients with DVT appear to be suitable for CDT.


2019 ◽  
Vol 10 (3) ◽  
pp. 1785-1788
Author(s):  
Priyanga Seemathan ◽  
SujathaBaskaran

Aim of the study is to determine the effect of passive, active and combined warmup on lower limb of healthy individuals. The methodology of the study is 30 individuals based on inclusion and exclusion criteria. Detailed procedure will be explained in patient words, and informed consent will be obtained from all participants. Effect of active, passive and combined warm-up will be evaluated in the subjects. The post-test value will be taken after four weeks. The results we determined from the static analysis has been revealed that there is a significant improvement in physical fitness of combined warm-up group than the active and passive warm-up separately. In the vertical jump test for passive warm-up group, the pre-test mean is 37.71, with the standard deviation being 6.53 and the post-test mean being 38.24 with a standard deviation of 6.60. And for the active warm-up group, the pre-test mean is 38.69, with the standard deviation being 6.606 and the post-test mean being 39.4 with a standard deviation 6.65. And for the combined warm-up group, the pre-test mean is 38.94, with the standard deviation being 7.12 and the post-test mean being 40.57 with a standard deviation of 6.88. Hence, we conclude that it has been proved statistically that although improvements have been observed in three groups, the improvement is much more significant in the combined warm-up group.


2020 ◽  
Vol 44 (5) ◽  
pp. 323-340
Author(s):  
Alex Hewson ◽  
Shaquitta Dent ◽  
Andrew Sawers

Background: Strength deficits may play a central role in the severity of balance, mobility, and endurance impairments in lower limb prosthesis users. A body of literature detailing the scope and specifics of muscle weakness in lower limb prosthesis users is emerging, but has yet to be summarized. A synopsis of strength deficits, and their impact on functional abilities in lower limb prosthesis users, may inform rehabilitation and research needs. Objectives: Synthesize reported strength deficits in lower limb prosthesis users, and discuss possible causes, consequences, and solutions. Study Design: Scoping review. Methods: A search of biomedical databases was performed, and inclusion/exclusion criteria were applied to identify publications relevant to the purpose of the review. Results: In all, 377 publications were identified, of which 12 met the inclusion/exclusion criteria. When compared with the controls and the intact limb, the primary strength outcome, peak torque, was lower in transtibial residual limb knee flexors and extensors, as well as transfemoral residual limb hip muscles. Conclusions: The reviewed studies provide evidence of strength deficits in lower limb prosthesis users. These deficits appear to be consequential, as they may contribute to balance, mobility, and endurance impairments. Additional research exploring alternative strength metrics, clinical tests, and causal links to functional impairments is required. Clinical relevance Evidence of muscle weakness among lower limb prosthesis users, and its influence on balance, mobility, and endurance, suggests that greater clinical attention and scientific inquiry into physical conditioning of lower limb prosthesis users is merited and required.


JAMA ◽  
1966 ◽  
Vol 197 (11) ◽  
pp. 915-916
Author(s):  
I. J. Schatz
Keyword(s):  

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