Isolation and diagnosis of bacteria causing urinary tract infection in pregnant and non pregnant females with diabetes mellitus type2

Diabetic patients have more outcomes of urinary tract infection than non diabetes, mortality of urinary tract infection (UTI) is 5 times higher in patients with diabetes old age, the incidence of urinary tract infection in pregnant women is slightly higher than non pregnant women, urinary tract infection in pregnant women either as a symptomatic bacteriiuria or symptomatic infection, which is more complication during pregnancy this present study was done in March 2016 to July 2016, the patients were females, total samples of 80 patient of pregnant and non pregnant with diabetes mellitus, selected from medical and general surgical wards, the samples were sending to teaching laboratories from the same hospital, the present study show that the incidence of UTI at non pregnant diabetic women occur at age (9-11) years (45%), the most common causative agents of UTI in diabetic pregnant females is Esherichia coli 20(50%), the results of microscopical examination of urine of pregnant with diabetes mellitus of urine of pregnant with diabetes mellitus revealed that (43), pyuria and (28) had crystals, and the result of microscopical examination of urine of non pregnant females with diabetes mellitus revealed that the common causative agent is Esherichia coli 3(30%), (9) had pyuria and (4) had crystals.

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Antibiotic Sensitivity in UTI among Diabetic Pregnant Women

Bangladesh Journal of Obstetrics & Gynaecology ◽

10.3329/bjog.v33i1.43546 ◽

2020 ◽

Vol 33 (1) ◽

pp. 54-58

Author(s):

N Naher ◽

F Begum ◽

N Hashem

Keyword(s):

Diabetes Mellitus ◽

Urinary Tract Infection ◽

Urinary Tract ◽

Tract Infection ◽

Pregnant Women ◽

Standard Procedure ◽

Antibiotic Sensitivity ◽

Successful Outcome ◽

E Coli ◽

Sensitivity Pattern

Background: Urinary tract infection (UTI) is common during pregnancy and especially soin pregnant patients with diabetes mellitus. The emergence of drug resistance and particularlythe extended spectrum Beta-lactamase production by Escherechia Coli and Methicillinresistance in staphylococci, limits the choice of anti-microbials. Method: A cross-sectional study was conducted on 50 pregnant women with sign andsymptoms of UTI in the Department of Obstetrics and Gynaecology, BIRDEM generalHospital-2 from January to June 2017. The objectives of the study were to determine thepresence and type of pathogens found in pregnant diabetic women presenting with featuresof urinary tract infection, and to analyze their antibiotic sensitivity pattern. Clean catch midstreamurine samples were collected using standard procedure and culture and sensitivitywas done following standard bacteriological method. Results: Mean age of the study subjects was 29.84±5.29 yrs; 48% were in third trimester ofpregnancy; 52% had Gestational Diabetes Mellitus (GDM) and 48% had Diabetes Mellitus(DM). Out of fifty pregnant women, thirty eight (76.0%) study subjects had positive growth.Of them, Escherechia coli was found in 57.9% cases, Klebsiellain 21.1%, Staphylococcusaureus in 7.9%, Enterococcus and Pseudomonas aeruginosa each in 2.6% case. Amikacinwas found to be sensitive to 100% cases of E. Coli, Klebsiella& Enterococcus but 100%resistant to Streptococcus. Conclusion: In this study, E. Coli was the most common organisms causing UTI, which isless susceptible to conventional oral antibiotics but more susceptible to amikacin. So carefulldrug selection is required for successful outcome in UTI. Bangladesh J Obstet Gynaecol, 2018; Vol. 33(1) : 54-58

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Urinary tract infection in pregnant females attending antenatal clinics among middle socioeconomic settings.

The Professional Medical Journal ◽

10.29309/tpmj/2020.27.08.4357 ◽

2020 ◽

Vol 27 (08) ◽

pp. 1636-1641

Author(s):

Mahjabeen Yaseen ◽

Sadia Rashid ◽

Shagufta Naqvi

Keyword(s):

Urinary Tract Infection ◽

Urinary Tract ◽

Tract Infection ◽

Pregnant Women ◽

College Hospital ◽

E Coli ◽

Medical College ◽

Pregnant Females ◽

Amoxicillin Clavulanic Acid ◽

Antenatal Clinics

Objectives: To determine the frequency of Urinary tract infection (UTI) and the antibiotic sensitivity patterns of isolated uropathogens in pregnant females among middle socioeconomic settings. Study Design: Retrospective Cross Sectional study. Setting: Jinnah Medical College Hospital Karachi. Period: From Jan 2017 to Dec 2017. Material & Methods: This retrospective study was carried out in Jinnah Medical College Hospital (JMCH) Karachi after taking ethical review board approval. All the pregnant women who were registered in antenatal clinics from January 2017 to December 2017 was included. Data was taken from medical record department and information about age, parity, gravida, miscarriages, microorganisms of the urine samples and their antibiotic susceptibility pattern was noted. Results: Five hundred and sixty-four pregnant women of age 17-44 years were registered in the hospital in antenatal clinics during the year 2017. Out of 564 females, 48 (8.50%) presented with urinary tract infection some time during their pregnancy period. Majority of patients (54.2%) were infected with Escherichia coli (E coli), followed by Klebsiella pneumonia (16.77%), Pseudomonas spp. (12.5%), Enterococcus spp. (8.3%) and Staphylococus aureus (8.3%). These etiologic agents vary in their sensitivity pattern to antibiotics. Piperacillin-tazobactam had the highest overall sensitivity of (89.6%). This was followed by Meropenem (87.5%), Nitrofurantoin (87.5%) and Fosfomycin (81.3%). Cefixime, Cefotaxime and Amoxicillin/ clavulanic acid had overall sensitivities above 50%. Conclusion: E coli was the common organisms followed by others gram negative and positive organisms. Enteroococus spp. was also a significant bacterial isolates in this settings. Meropenem, Piperacillin-tazobactam, Nitrofurantoin, Fosfomycin were the highly effective antibiotics against isolated uropathogens. Amoxicillin/clavulanic acid and Cephalosporin also had a good results.

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Relationship between Diabetes mellitus and Urinary tract infections

Baghdad Science Journal ◽

10.21123/bsj.5.2.173-177 ◽

2008 ◽

Vol 5 (2) ◽

pp. 173-177

Author(s):

Baghdad Science Journal

Keyword(s):

Diabetes Mellitus ◽

Urinary Tract Infection ◽

Urinary Tract ◽

Tract Infection ◽

Urinary Tract Infections ◽

Causative Agent ◽

Penicillin G ◽

Diabetic Patients ◽

Bacterial Sensitivity ◽

Tract Infections

Blood and urine samples were collected from 203 patients to study the relationship between Diabetes mellitus and urinary tract infections (UTI). Blood and urine specimens were subjected for estimation of random blood sugar, in addition to detection of the most pathogen bacteria which cause urinary tract infection in diabetic patients. The study included the detection of bacterial sensitivity to some antibiotics used in treating urinary tract infections, and also included the study of genetic basis which cause both types of diabetes mellitus. The results can be summarized as follows: The incidence of type ? diabetes in males was (35.8%), and (45.9%) in females . and type 2 diabetes in males was (49.6%), while in females was (40.16%).The incidence of urinary tract infection in females was higher (69.6%) in comparison to males (37%).Escherichia coli was the most causative agent of urinary tract infections in diabetic males (19.7%), while Candida albicans was the most causative agent in urinary tract infections in females (18.8%).The majority of isolated bacteria were highly resistant to Gentamycin, Tetracycline, Ampicillin, Penicillin G, while they were sensitive to Cephotaxim, Cephalexin, Ciprofloxacin.

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Risk Factors in Diabetes and Pregnant Women with Urinary Tract Infections Compared to Younger Aged Female.

International Journal of Medical Sciences ◽

10.32441/ijms.v1i3.99 ◽

2018 ◽

Vol 1 (3) ◽

pp. 26-38

Author(s):

Abdulghani Mohamed Alsamarai ◽

Shler Ali Khorshed

Keyword(s):

Risk Factors ◽

Urinary Tract Infection ◽

Urinary Tract ◽

Tract Infection ◽

Pregnant Women ◽

Female Student ◽

Mean Value ◽

Infected Female ◽

Significant Difference ◽

Tract Infections

Background: Urinary tract infection is common with health impact in women and characterised by failure to treatment and recurrent episodes. Aim: This study was conducted to determine the risk factors for the development of urinary tract infection in diabetic and pregnant women in comparison to student female. Materials and methods: A prospective cross-sectional study conducted during the period from 1st of June 2015 to the end of January 2016. The population included in the study are 563 women, of them 425 were outpatients, and 138 were inpatients. Their age range between 18 and 80 years, with a mean age of 33.59±15.29 years. Urine samples collected and cultured on blood agar and MacConkey agar by spread plate technique. Bacterial colonies with different morphology were selected, purified and identified according to their biochemical characteristics using conventional standard methods. Results: In diabetic women, there were no significant difference in mean age and BMI values between culture positive and culture negative groups. However, pus cell mean scale was significantly higher [P=0.000] in women with urinary tract infection [1.76±1.25] than in those with negative culture [0.69±1.00]. In pregnant women, BMI mean value was significantly [P=0.013] lower in pregnant women with UTI [26.14] as compared to those without infection [26.99]. Pus cell scale mean value was significantly [P=0.000] higher in pregnant women with UTI [1.55] than women with negative UTI [0.85]. While there was no significant difference in mean age between UTI positive and negative pregnant women. In female student, there was a significant difference between UTI infected and non-infected in mean age [P=0.041] and pus cell scale [P=0.000]. However, BMI was not significantly different between infected and non-infected female student. Other risk factors association are variables in the 3 groups when analysed using X2, while AUC and OR show different trends of association between risk factors and UTI. Conclusion: BMI, pus cell scale, child number, delivery method, operation history and hospital setting were significantly associated with culture positivity in the 3 studied groups as determined by AUC. While OR confirmed association with pus sale scale in the 3 groups.

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Susceptibility to Antibiotics among Isolated Gram Negative Bacilli from Urine Sample in non Pregnant Women with Urinary Tract Infection

10.24086/bios17.27 ◽

2017 ◽

Author(s):

Sahla Abbas ◽

Najdat Mahdi ◽

Khalaf Ahmed

Keyword(s):

Urinary Tract Infection ◽

Urinary Tract ◽

Tract Infection ◽

Pregnant Women ◽

Urine Sample ◽

Gram Negative

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Isolation, Identification, and characterization of Microbial that caused Urinary Tract Infection in pregnant women/Iraq

International Journal of Pharmaceutical Research ◽

10.31838/ijpr/2020.12.01.094 ◽

2020 ◽

Vol 12 (1) ◽

Keyword(s):

Urinary Tract Infection ◽

Urinary Tract ◽

Tract Infection ◽

Pregnant Women ◽

Identification And Characterization

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Safety of SGLT2 Inhibitors in Patients with Diabetes Mellitus

Current Drug Safety ◽

10.2174/1574886314666190206164647 ◽

2019 ◽

Vol 14 (2) ◽

pp. 87-93 ◽

Cited By ~ 7

Author(s):

Mahakpreet Singh ◽

Ruchika Sharma ◽

Anoop Kumar

Keyword(s):

Diabetes Mellitus ◽

Urinary Tract Infection ◽

Urinary Tract ◽

Tract Infection ◽

Diabetic Ketoacidosis ◽

Adverse Drug Reactions ◽

Sglt2 Inhibitor ◽

Sglt2 Inhibitors ◽

Drug Reactions ◽

Authorization Holder

Background:Recently, Food and Drug Administration (FDA) has approved sodium/ glucose co-transporter 2 (SGLT2) inhibitors for the treatment of diabetes mellitus. However, regarding adverse drug reactions (ADRs) of SGLT2 inhibitors in large group of population, very less information is available. Thus, we have tried to find out the risk profile of SGLT2 inhibitors. Materials and Methods: A total of 1,042 studies have been published from Nov. 2012-Nov. 2017 regarding SGLT2 inhibitors. After inclusion and exclusion criteria, 27 studies have been selected for the analysis of risk. Results and Discussion:The emerging evidence indicates various adverse drug reactions such as foot and toe amputation, cancer, diabetic ketoacidosis, bone fracture risk and urinary as well as mycotic genital infection. The causality assessment has shown a correlation between SGLT2 inhibitors and diabetic ketoacidosis and urinary tract infection. Conclusion:In conclusion, Marketing Authorization Holder (MAH) and Regulatory Authorities (RA) should monitor various adverse drug reactions such as diabetic ketoacidosis and urinary tract infection with the use of SGLT2 inhibitor.

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Effect of An Educational Intervention on Pregnant Women’s Knowledge and Self-Care Practices Regarding Urinary Tract Infection

Evidence-Based Nursing Research ◽

10.47104/ebnrojs3.v2i4.194 ◽

2021 ◽

Vol 2 (4) ◽

pp. 11

Author(s):

Hemmat M. El-bana ◽

Hanan A. Ali

Keyword(s):

Urinary Tract Infection ◽

Urinary Tract ◽

Tract Infection ◽

Pregnant Women ◽

Educational Intervention ◽

Self Care ◽

Post Intervention ◽

Care Practices ◽

Women's Knowledge ◽

Women’S Knowledge

Contents: The most prevalent type of infection during pregnancy is urinary tract infections (UTIs). It affects up to ten percent of pregnant women and may cause serious adverse pregnancy outcomes for both mother and fetus. Aim: The research aimed to evaluate the effect of an educational intervention on pregnant women’s knowledge and self-care practices regarding urinary tract infection. Methods: A quasi-experimental (pre/post-test) design was adopted to fulfill this study's aim. The study was conducted at the Obstetrics and Gynaecological outpatient clinic in Benha university hospital on a purposive sample of 68 pregnant women among those attending the setting mentioned above. Two key instruments were used to collect data: A structured interviewing questionnaire, self-care practices checklist. Results: revealed a highly statistically significant difference in pregnant women's knowledge and self-care practices related to urinary tract infection at post-intervention compared to their pre-intervention phase (p-values < 0.001). A highly significant positive correlation was illustrated between studied women's total knowledge and total practice scores at pre (p=0.04) and post-intervention (p=0.000) phases. Conclusion: The study concluded that the research hypothesis is supported, and pregnant women exhibited better knowledge and self-care practices regarding (UTI) during pregnancy after implementing an educational intervention than before. The study recommended that knowledge and self-care concepts regarding UTI through antenatal screening programs in early pregnancy should be empowered as an essential part of all women's health care levels and strategies.

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