scholarly journals Incidence and Types of Congenital Heart Diseases among Children in Sulaimani Governorate

2017 ◽  
Vol 2 (2) ◽  
pp. 106-111 ◽  
Author(s):  
Niaz Kamal ◽  
Nasih Othman ◽  
Aso Salih
Keyword(s):  
Tetralogy Of Fallot ◽  
Teaching Hospital ◽  
Congenital Heart ◽  
Septal Defect ◽  
Heart Diseases ◽  
Congenital Defects ◽  
Congenital Heart Diseases ◽  
Live Births ◽  
Septal Defects ◽  
Significant Difference

Congenital heart diseases (CHD) are common causes of cardiovascular morbidity and mortality among young children and adolescents. It is the most common form of structural congenital defects. Little is known about incidence and type of these disorders in Sulaimani. Therefore, this study was undertaken to determine the incidence of congenital heart diseases and their types in Sulaimani Governorate. The study was conducted in Sulaimani Pediatric Teaching Hospital and the Maternity Hospital during January 2015 to December 2016. A sample of 400 consecutive cases of CHD in children aged 0-12 years was recruited attending the echocardiographic department of the hospital for diagnosis or follow-up purposes. Demographic data was collected through a face-to-face interview with the mothers of cases. A total number of new live births for 2015-2016 and those with congenital heart diseases were obtained from the medical records of the department of statistics of Sulaimani Maternity Teaching Hospital. The overall incidence of all types of congenital heart diseases was 1.7/1000, 1.6/1000 live births for the year 2015 and 2016 respectively. There was a statistically significant difference in incidence between males and females over the two years, male to female risk ratio 1.83 (95% CI 1.09-3.14, p 0.007). The commonest types of cyanotic congenital heart diseases were tetralogy of Fallot (38.9% of all cyanotic defects), complete atrioventricular canal (22.1%), and transposition of great arteries (18.2%), while the most common types of non-cyanotic congenital heart disease were atrial septal defect (34.1% of all non-cyanotic defects), ventricular septal defect (31.6%), and the other defects are less common. In conclusion, tetralogy of Fallot, atrial septal defects, and ventricular septal defects are the commonest congenital heart deformities in Sulaimani Governorate; the incidence is lower than other countries but this could be an underestimation.

Incidence of congenital heart diseases in children born at Eastern Regional Referral Hospital, Monggar

2016 ◽  
Vol 2 (1) ◽  
pp. 1-4
Author(s):  
Purushotam Bhandari ◽  
Kezang Wangmo
Keyword(s):  
Birth Defects ◽  
Congenital Heart ◽  
Septal Defect ◽  
Heart Diseases ◽  
Referral Hospital ◽  
Congenital Heart Diseases ◽  
Regional Referral Hospital ◽  
True Incidence ◽  
Live Births ◽  
Eastern Regional

Introduction: Congenital heart diseases are the commonest birth defects worldwide. While the true incidence of congenital heart diseases is known in many countries, it has not been studied in Bhutan. Methods: Neonates born at the Eastern Regional Referral Hospital, Monggar in the year 2010 were screened for congenital heart diseases at birth by echocardiography and clinical examination including pulse oximetry. Results: The majority of the study subjects were natives of eastern districts of Bhutan. The incidence of congenital heart diseases was found to be 68 per 1000 live births, with Atrial Septal Defect being the commonest lesion. Conclusions: The overall incidence of congenital heart disease is higher than what is reported in other countries although the incidence of serious lesions was similar to what is reported elsewhere.

Plasma Atrial Natriuretic Peptide in Patients With Congenital Heart Diseases

PEDIATRICS ◽  
1988 ◽  
Vol 82 (4) ◽  
pp. 639-643
Author(s):  
Suguru Matsuoka ◽  
Yoshihide Kurahashi ◽  
Yohko Miki ◽  
Masuhide Miyao ◽  
Yasuhiro Yamazaki ◽  
...  
Keyword(s):  
Atrial Natriuretic Peptide ◽  
Natriuretic Peptide ◽  
Congenital Heart ◽  
Septal Defect ◽  
Heart Diseases ◽  
Ductus Arteriosus ◽  
Right Atrial ◽  
Congenital Heart Diseases ◽  
Septal Defects ◽  
Atrial Natriuretic

The plasma level of human α-atrial natriuretic peptide was measured in healthy children and patients, 1 month to 15 years of age, with congenital heart diseases. Significant increases were found in patients with a ventricular septal defect, tricuspid valve atresia, patent ductus arteriosus, and atrial septal defect but not in those with pulmonary valve stenosis or tetralogy of Fallot. The levels were significantly higher in children with ventricular septal defects (221 ± 123 pg/mL) or patent ductus arteriosus (124 ± 38 pg/mL) than in those with atrial septal defects (65 ± 42 pg/mL) (P < .01). The increased levels appeared to be correlated with enlargement of the left atrium (r = .85, P < .01) but not with the right atrial size or the mean right atrial pressure. They were higher in younger than in older healthy infants, but this age difference did not affect the results. These findings indicate that human α-atrial natriuretic peptide is released into the circulation in response to chronic atrial expansion in patients with congenital heart disease and may have an important role in volume homeostasis.

Prenatal differential ultrasound diagnosis of congenital heart diseases with interventricular septal defect and dextroposed aorta

2017 ◽  
Author(s):  
M.V. Medvedev, M.V. Kubrina
Keyword(s):  
Congenital Heart ◽  
Septal Defect ◽  
Heart Diseases ◽  
Prenatal Ultrasound ◽  
Ultrasound Diagnosis ◽  
Congenital Heart Diseases

Main prenatal ultrasound differential patterns of congenital heart diseases including interventricular septal defect and dextroposed aorta are presented.

The case for preoperative coronary angiography in patients with tetralogy of Fallot and other complex congenital heart diseases

1982 ◽  
Vol 103 (3) ◽  
pp. 451-456 ◽  
Author(s):  
Bruce M. McManus ◽  
Bruce F. Waller ◽  
Michael Jones ◽  
Stephen E. Epstein ◽  
William C. Roberts
Keyword(s):  
Coronary Angiography ◽  
Tetralogy Of Fallot ◽  
Congenital Heart ◽  
Heart Diseases ◽  
Congenital Heart Diseases

scholarly journals Characterization of SMAD3 Gene Variants for Possible Roles in Ventricular Septal Defects and Other Congenital Heart Diseases

PLoS ONE ◽  
2015 ◽  
Vol 10 (6) ◽  
pp. e0131542 ◽  
Author(s):  
Fei-Feng Li ◽  
Jing Zhou ◽  
Dan-Dan Zhao ◽  
Peng Yan ◽  
Xia Li ◽  
...  
Keyword(s):  
Congenital Heart ◽  
Heart Diseases ◽  
Congenital Heart Diseases ◽  
Gene Variants ◽  
Ventricular Septal Defects ◽  
Septal Defects

scholarly journals Parental occupational exposure and congenital heart diseases in a Hungarian case–control study

2020 ◽  
Author(s):  
Vince Fazekas-Pongor ◽  
Mónika Fekete ◽  
Melinda Csáky-Szunyogh ◽  
Károly Cseh ◽  
Melinda Pénzes
Keyword(s):  
Occupational Exposure ◽  
Congenital Heart ◽  
Heart Diseases ◽  
Case Control ◽  
Congenital Heart Diseases ◽  
Entire Spectrum ◽  
Septal Defects ◽  
Atrial Septal Defects ◽  
Hungarian Case ◽  
Parental Occupational Exposure

Abstract Purpose Our study aimed to explore the effect of parental occupational exposure to endocrine disrupting chemicals (EDCs) on the development of congenital heart diseases (CHDs) in the offspring, and to compare job-exposure matrix (JEM)-assessed and self-reported occupational exposures with each other. Methods Live-born infants born in 2007–2008 were selected from the population-based Hungarian Case–Control Surveillance of Congenital Abnormalities Study. 577 cases with any CHDs were compared to 1731 matched controls. Parental periconceptional occupational exposure to EDCs was assessed by a JEM and by questionnaire-based self-reporting of parents. Multivariate conditional logistic regression analyses were conducted to explore associations between parental occupational exposure to EDCs and the entire spectrum of CHDs and by CHD subtypes in the offspring. Kappa statistics were also performed to determine the consistency among JEM-assessed and self-reported occupational exposure of parents. Results JEM-assessed paternal exposure to polychlorinated organic substances, phthalates, biphenolic compounds, and solvents were significantly associated with the entire spectrum of CHDs. Ventricular septal defects were significantly associated with paternal self-reported exposure to pesticides, while atrial septal defects were significantly associated to paternal JEM-assessed phthalate exposure. Paternal solvent exposure was significantly associated with atrial septal defects and right ventricle outflow tract obstructions. JEM-assessed and self-reported exposures to pesticides, heavy metals, and solvents exhibited poor agreement for mothers and slight agreement for fathers. Conclusion Even though parental occupational exposure to EDCs seems to have a minor impact on the occurrence of CHDs, the results of biological and environmental monitoring should be taken into consideration as well.

scholarly journals High prevalence of congenital heart disease at high altitudes in Tibet

2018 ◽  
Vol 26 (7) ◽  
pp. 756-759 ◽  
Author(s):  
Hua Chun ◽  
Yan Yue ◽  
Yibin Wang ◽  
Zhaxi Dawa ◽  
Pu Zhen ◽  
...  
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Patent Ductus Arteriosus ◽  
High Altitude ◽  
Congenital Heart ◽  
Septal Defect ◽  
Heart Diseases ◽  
Ductus Arteriosus ◽  
Congenital Heart Diseases ◽  
Patent Ductus

Background Previous small sample studies suggested that elevated altitudes might be associated with the incidence of cardiovascular diseases. However, it remains uncertain whether high altitudes (over 3000 m above sea level) are related to congenital heart disease. We therefore explored the prevalence of congenital heart disease in a large cohort of students in the world's largest prefecture-level city with the highest altitude. Methods This cross-sectional study included 84,302 student participants (boys 52.12%, girls 47.88%, with an average age of 10.62 ± 3.33 years). Data were extracted from the screening results among different altitude area schools in Nagqu from June 2016 to August 2017. Students were first screened by performing a physical examination consisting of cardiac auscultations and clinical manifestation screenings. An echocardiography was performed to confirm and identify the subtype of congenital heart disease. Results The prevalence of congenital heart disease among students in Nagqu, Tibet, was 5.21‰ (439 cases). The most common congenital heart disease type was patent ductus arteriosus, representing 66.3% of congenital heart diseases diagnosed in this study, followed by atrial septal defect and ventricular septal defect, representing 20.3% and 9.1% of congenital heart diseases, respectively. Students living in higher altitudes were significantly more prone to have congenital heart disease than students in locations with lower altitudes. The prevalence of congenital heart disease in girls was found to be higher than that of boys. Conclusions The correlation between congenital heart disease and increased altitude is noteworthy. This study's results are the first big data epidemiological investigation to confirm that high altitude is a significant environmental risk factor for congenital heart disease, especially patent ductus arteriosus. Furthermore, the results provide additional support to make a diagnostic and treatment plan to prevent congenital heart disease in high altitude areas.

scholarly journals Structure of unoperated congenital heart diseases in children of Zabaikalsky Territory

2020 ◽  
pp. 83-89
Author(s):  
A.V. Ignatieva ◽  
◽  
O.F. Sibira ◽  
I.N. Gaimolenko ◽  
◽  
...  
Keyword(s):  
Surgical Treatment ◽  
Congenital Heart ◽  
Heart Diseases ◽  
Exclusion Criterion ◽  
First Year ◽  
Congenital Heart Diseases ◽  
Significance Level ◽  
Septal Defects ◽  
Stage 1 ◽  
First Time

The aim of the research is to study the morbidity by appealability and some characteristics of congenital heart diseases in children of Zabaikalsky Territory. Material and methods. A retrospective clinical and anamnestic analysis of children with congenital heart diseases without surgical treatment, who were hospitalized, was carried out. The analysis included 3 year-observation. CHD diagnosed is an inclusion criterion; while surgical treatment of heart diseases is exclusion criterion. Statistical data processing was carried out using Microsoft Excel 2007, Statistica v.10.0 software package. χ2 test (Pearson) was used to compare two independent groups by qualitative characteristics. The results were considered statistically significant (reliable) at the achieved significance level of p <0.05. Results. In Zabaikalsky Territory, approximately 200 children with congenital heart disease without surgical treatment are hospitalized annually; the average age is 3 years. Fifty-three per cent of children applied for inpatient care for the first time, 44% of them were children at their first year. Gender distribution indicates the highest incidence of the pathology in girls. In CHD structure, atrial septal defects are on the first place, while interventricular septal defects are on the second. Combination of ASD and IVSD was observed with approximately equal frequency. Chronic heart failure associated with CHD was registered in 77% of children. In most cases CHF, stage 1, was diagnosed (63%). In 2/3 of cases, pulmonary hypertension of various severity was detected. Analysis of place of residence of children with CHD in the Zabaikalsky Territory shows that children from areas with the highest population density are hospitalized more often. Conclusion. The problem of congenital heart diseases in children of Zabaikalsky Territory is of current importance due to the widespread prevalence and high specific gravity among all internal organ defects in children of this region.

scholarly journals Tetralogy of Fallot with Double Aortic Arch in an 8-Month-Old Girl: A Rare Association

2020 ◽  
Vol 23 (4) ◽  
pp. E507-E509
Author(s):  
Huang Feng ◽  
Xiaohui Bian ◽  
Yuru Lan ◽  
Yunfei Ling ◽  
Yong jun Qian
Keyword(s):  
Aortic Arch ◽  
Tetralogy Of Fallot ◽  
Rare Case ◽  
Congenital Heart ◽  
Heart Diseases ◽  
Relative Size ◽  
Double Aortic Arch ◽  
Congenital Heart Diseases ◽  
Rare Congenital Anomaly ◽  
Rare Association

Double aortic arch (DAA) is an extremely rare congenital anomaly that can be divided into right dominant, left dominant, and balanced DAA according to the relative size of the two arches. The incidence of balanced DAA is only 5% among double arch anomalies. DAA is symptomatic only when it produces symptoms secondary to compression of the trachea or esophagus. DAA is rarely associated with other congenital heart diseases. In this report, we present a rare case of asymptomatic DAA combined with Tetralogy of Fallot (TOF) in an 8-month-old girl.

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