Prenatal differential ultrasound diagnosis of congenital heart diseases with interventricular septal defect and dextroposed aorta

2017 ◽  
Author(s):  
M.V. Medvedev, M.V. Kubrina
Keyword(s):  
Congenital Heart ◽  
Septal Defect ◽  
Heart Diseases ◽  
Prenatal Ultrasound ◽  
Ultrasound Diagnosis ◽  
Congenital Heart Diseases

Main prenatal ultrasound differential patterns of congenital heart diseases including interventricular septal defect and dextroposed aorta are presented.

scholarly journals High prevalence of congenital heart disease at high altitudes in Tibet

2018 ◽  
Vol 26 (7) ◽  
pp. 756-759 ◽  
Author(s):  
Hua Chun ◽  
Yan Yue ◽  
Yibin Wang ◽  
Zhaxi Dawa ◽  
Pu Zhen ◽  
...  
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Patent Ductus Arteriosus ◽  
High Altitude ◽  
Congenital Heart ◽  
Septal Defect ◽  
Heart Diseases ◽  
Ductus Arteriosus ◽  
Congenital Heart Diseases ◽  
Patent Ductus

Background Previous small sample studies suggested that elevated altitudes might be associated with the incidence of cardiovascular diseases. However, it remains uncertain whether high altitudes (over 3000 m above sea level) are related to congenital heart disease. We therefore explored the prevalence of congenital heart disease in a large cohort of students in the world's largest prefecture-level city with the highest altitude. Methods This cross-sectional study included 84,302 student participants (boys 52.12%, girls 47.88%, with an average age of 10.62 ± 3.33 years). Data were extracted from the screening results among different altitude area schools in Nagqu from June 2016 to August 2017. Students were first screened by performing a physical examination consisting of cardiac auscultations and clinical manifestation screenings. An echocardiography was performed to confirm and identify the subtype of congenital heart disease. Results The prevalence of congenital heart disease among students in Nagqu, Tibet, was 5.21‰ (439 cases). The most common congenital heart disease type was patent ductus arteriosus, representing 66.3% of congenital heart diseases diagnosed in this study, followed by atrial septal defect and ventricular septal defect, representing 20.3% and 9.1% of congenital heart diseases, respectively. Students living in higher altitudes were significantly more prone to have congenital heart disease than students in locations with lower altitudes. The prevalence of congenital heart disease in girls was found to be higher than that of boys. Conclusions The correlation between congenital heart disease and increased altitude is noteworthy. This study's results are the first big data epidemiological investigation to confirm that high altitude is a significant environmental risk factor for congenital heart disease, especially patent ductus arteriosus. Furthermore, the results provide additional support to make a diagnostic and treatment plan to prevent congenital heart disease in high altitude areas.

Incidence of congenital heart diseases in children born at Eastern Regional Referral Hospital, Monggar

2016 ◽  
Vol 2 (1) ◽  
pp. 1-4
Author(s):  
Purushotam Bhandari ◽  
Kezang Wangmo
Keyword(s):  
Birth Defects ◽  
Congenital Heart ◽  
Septal Defect ◽  
Heart Diseases ◽  
Referral Hospital ◽  
Congenital Heart Diseases ◽  
Regional Referral Hospital ◽  
True Incidence ◽  
Live Births ◽  
Eastern Regional

Introduction: Congenital heart diseases are the commonest birth defects worldwide. While the true incidence of congenital heart diseases is known in many countries, it has not been studied in Bhutan. Methods: Neonates born at the Eastern Regional Referral Hospital, Monggar in the year 2010 were screened for congenital heart diseases at birth by echocardiography and clinical examination including pulse oximetry. Results: The majority of the study subjects were natives of eastern districts of Bhutan. The incidence of congenital heart diseases was found to be 68 per 1000 live births, with Atrial Septal Defect being the commonest lesion. Conclusions: The overall incidence of congenital heart disease is higher than what is reported in other countries although the incidence of serious lesions was similar to what is reported elsewhere.

Plasma Atrial Natriuretic Peptide in Patients With Congenital Heart Diseases

PEDIATRICS ◽  
1988 ◽  
Vol 82 (4) ◽  
pp. 639-643
Author(s):  
Suguru Matsuoka ◽  
Yoshihide Kurahashi ◽  
Yohko Miki ◽  
Masuhide Miyao ◽  
Yasuhiro Yamazaki ◽  
...  
Keyword(s):  
Atrial Natriuretic Peptide ◽  
Natriuretic Peptide ◽  
Congenital Heart ◽  
Septal Defect ◽  
Heart Diseases ◽  
Ductus Arteriosus ◽  
Right Atrial ◽  
Congenital Heart Diseases ◽  
Septal Defects ◽  
Atrial Natriuretic

The plasma level of human α-atrial natriuretic peptide was measured in healthy children and patients, 1 month to 15 years of age, with congenital heart diseases. Significant increases were found in patients with a ventricular septal defect, tricuspid valve atresia, patent ductus arteriosus, and atrial septal defect but not in those with pulmonary valve stenosis or tetralogy of Fallot. The levels were significantly higher in children with ventricular septal defects (221 ± 123 pg/mL) or patent ductus arteriosus (124 ± 38 pg/mL) than in those with atrial septal defects (65 ± 42 pg/mL) (P < .01). The increased levels appeared to be correlated with enlargement of the left atrium (r = .85, P < .01) but not with the right atrial size or the mean right atrial pressure. They were higher in younger than in older healthy infants, but this age difference did not affect the results. These findings indicate that human α-atrial natriuretic peptide is released into the circulation in response to chronic atrial expansion in patients with congenital heart disease and may have an important role in volume homeostasis.

scholarly journals P369 Patient specific virtual reality for education in congenital heart disease

2020 ◽  
Vol 21 (Supplement_1) ◽  
Author(s):  
E G Milano ◽  
E Pajaziti ◽  
S Schievano ◽  
A Cook ◽  
C Capelli
Keyword(s):  
Virtual Reality ◽  
Congenital Heart ◽  
Septal Defect ◽  
Heart Diseases ◽  
Ductus Arteriosus ◽  
3D Models ◽  
Background Information ◽  
Patient Specific ◽  
Congenital Heart Diseases ◽  
Cardiac Morphology

Abstract Funding Acknowledgements La Fondation Dassault Systèmes, British Heart Foundation Background Virtual reality (VR) provides a unique possibility to interact with three-dimensional objects. Still in its infancy, the integration of VR with advanced cardiovascular imaging technology allows users to handle patient-specific cardiac models. Purpose The purpose of this study was to evaluate the potential role of VR in teaching cardiac morphology of congenital heart diseases to healthcare professionals. Methods From October 2018 to April 2019, a VR application was developed in-house and incorporated within the Cardiac Morphology courses run monthly at our centre. The VR software included patient-specific 3D models which were reconstructed from 3D imaging datasets (micro-CT, CT, CMR or 3D echo data). The most important cardiac structures were labelled to allow easier identification of anatomical features (Figure 1). Each participant had the possibility to evaluate 6 different patient specific models including: a foetal normal heart, a foetal Transposition of the Great Arteries, a foetal Atrioventricular septal defect, a four-month-old Tetralogy of Fallot, a four-month-old Double Outlet Right Ventricle with uncommitted ventricular septal defect and a one-year-old Patent Ductus Arteriosus. All the attendees could evaluate the models individually for 5 to 15 minutes. A short survey with six questions was administered at the end of the session. The survey included sections asking for professional background information, prior VR experience and feedback on the VR experience which was assessed with a 5 points Likert-type scale (from 1 to 5). Results The VR session was attended by 20 delegates with mixed professional backgrounds including cardiac surgeons, cardiologists, cardiac anaesthesiologists, paediatricians, pathologists and medical students. Only 2 out of 20 had tried a virtual reality application before, although neither of those prior VR experiences had a medical focus. The VR application was considered ‘’extremely helpful’’ (5/5) in understanding the anatomy by 44% of participants, and ‘’very helpful’’(4/5) by another 44%. The methods of interaction (e.g. grabbing objects, using a cutting tool) were considered "extremely intuitive’’ (5/5) by 72% of attendees, and "very intuitive"(4/5) by 27%. In 94% of the cases, the attendees responded to be "very willing"(4/5) or "extremely willing"(5/5) to implement a VR setup at their own institutions for the purpose of evaluating cardiac anatomies. Conclusion The use of the VR station in cardiac morphology courses was very well received by the attendees, as it is frequently considered easy to use and very helpful in aiding the understanding of congenital heart diseases. The survey highlighted a great potential for implementing this tool in educational programmes. Abstract P369 Figure 1

scholarly journals Pattern of Congenital Heart Diseases and Treatment Options in a Bangladeshi Centre: Analysis of 6914 cases from Non-invasive Cardiac Laboratory

2017 ◽  
Vol 9 (2) ◽  
pp. 97-105
Author(s):  
Nurun Nahar Fatema
Keyword(s):  
Down Syndrome ◽  
Chromosomal Abnormality ◽  
Congenital Heart ◽  
Septal Defect ◽  
Heart Diseases ◽  
Ductus Arteriosus ◽  
Treatment Options ◽  
Atrioventricular Septal Defect ◽  
Congenital Heart Diseases ◽  
Transposition Of Great Arteries

Background: Echocardiography is the most sensitive tool to diagnose congenital heart diseases efficiently. It can be repeated as many times as required to see the progress, outcome of treatment and complications. Echocardiography laboratory can give a scenario of pattern of congenital heart diseases existing in Bangladesh as well as natural history of the cases and treatment options offered.Methods: It is a retrospective review of database of echocardiography patient from pediatric noninvasive laboratory of a cardiac hospital from January 2012 to December 2012.Results: Out of 6914 cases 55.73% were male and 44.27% female. Neonates include 8.48%, 36.62% Down Syndrome were infant, 34.02% were under 5 years, 17.97% were children and adolescents and 2.96% were adults. Normal Echocardiography finding was found in 17.28% cases. Ventricular septal defect (VSD) was found in 18.60% cases, Atrial septal defects (ASD) in 15.41% cases, Patent ductus arteriosus (PDA) in 8.59% cases, Atrioventricular septal defect (AVSD) in 1.97% cases, Tetralogy of Fallot (TOF) in 4.79% cases and Transposition of great arteries (TGA) in 2.26% cases. Down syndrome was the commonest chromosomal abnormality seen in 2.4% cases.Conclusion: This study shows that VSD is the commonest congenital heart lesions in our country followed by ASD. Down syndrome was the commonest chromosomal abnormality seen in 2.4% cases.Cardiovasc. j. 2017; 9(2): 97-105

scholarly journals Spectrum of cardiovascular diseases at a referral tertiary care hospital in Somalia, Mogadishu: an echocardiographic study

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Gökhan Alıcı ◽  
Ömer Genç
Keyword(s):  
Heart Disease ◽  
Cardiovascular Diseases ◽  
Congenital Heart ◽  
Septal Defect ◽  
Heart Diseases ◽  
Tertiary Care ◽  
Hypertensive Heart Disease ◽  
Mitral Insufficiency ◽  
Congenital Heart Diseases ◽  
Care Hospital

Abstract Background To investigate the frequencies and patterns of cardiovascular diseases (CVDs), including rheumatic and congenital heart diseases, among patients with abnormal hearts assessed by echocardiographic examination. Methods This retrospective, descriptive registry reviewed abnormal echocardiographic findings of 1140 patients aged 0–100 years who were admitted to the cardiology outpatient clinic at a tertiary training institution in Mogadishu. Results Hypertensive heart disease (HHD) (n:454, 39.8%), valvular heart disease (VHD) (n:395, 34.6%), and heart failure with reduced ejection fraction (HFrEF) (n:351, 30.8%) were the most frequent comorbidities. Congenital heart diseases (CHDs) were detected in 151 (13.2%) of the patients, with the most common ones including atrial septal defect (ASD) (n:37, 3.2%) and ventricular septal defect (VSD) (n:26, 2.3%). Rheumatic heart disease (RHD) was observed in 84 (7.4%) patients, among whom the most common age range was 16–30 years (40.5%), followed by 31–45 years (31%) and 0–15 years (15.5%). Mitral insufficiency (n:541, 47.5%) was detected as the most frequent VHD, followed by aortic insufficiency (n:437, 38.3%), and tricuspid insufficiency (n:264, 23.2%) and mitral valve stenosis (n:39, 3.4%) was the least common VHD. Conclusion In the present study, we found that HHD was the most common comorbidity, followed by VHD, and HFrEF. Moreover, the most common VHD was mitral insufficiency and the most common CHD was ASD.

scholarly journals Spectrum of Heart Diseases at a Referral Tertiary Care Hospital in Somalia, Mogadishu: An Echocardiographic Study

2021 ◽  
Author(s):  
Gökhan Alıcı ◽  
Ömer Genç
Keyword(s):  
Heart Disease ◽  
Congenital Heart ◽  
Septal Defect ◽  
Tertiary Care Hospital ◽  
Heart Diseases ◽  
Tertiary Care ◽  
Valvular Disease ◽  
Mitral Insufficiency ◽  
Congenital Heart Diseases ◽  
Care Hospital

Abstract Background: To investigate the frequencies and patterns of cardiovascular diseases (CVD), including rheumatic and congenital heart diseases, assessed by echocardiographic examinations in the only referral tertiary care hospital in Mogadishu, the capital of Somalia.Methods: This retrospective, descriptive registry reviewed the pathological echocardiographic findings of 1140 patients aged 0-100 years who were admitted to the cardiology outpatient clinic in a tertiary training hospital in Mogadishu.Results: Hypertensive heart disease (HHD) 454 (39.8%) and degenerative valvular disease 395 (34.6%) were the most common comorbidities. Congenital heart diseases (CHD) were detected in 151 (13.2%) of the patients, with the most common ones including atrial septal defect (ASD) 37 (3.2%) and ventricular septal defect (VSD) 26 (2.3%).Rheumatic heart disease (RHD) was detected in 84 (7.4%) patients, among whom the most common age range was 16-30 years (40.5%), followed by 31-45 years (31%) and 0-15 years (15.5%). Conclusıon: In the present study, we found that HHD was the most common comorbidity , followed by degenerative valvular disease, Heart failure with reduced ejection fraction(HFrEF),and Ischemic heart disease(IHD).Moreover, the most common valvular disease was mitral insufficiency and the most common CHD was ASD.

scholarly journals A case of an uncorrected double outlet right ventricle with ventricular septal defect in pregnancy

2019 ◽  
Vol 8 (9) ◽  
pp. 3805
Author(s):  
Kedar M. Tilak ◽  
Uma N. Wankhede
Keyword(s):  
Congenital Heart Disease ◽  
Right Ventricle ◽  
Congenital Heart ◽  
Multidisciplinary Approach ◽  
Septal Defect ◽  
Heart Diseases ◽  
Double Outlet Right Ventricle ◽  
Congenital Heart Diseases ◽  
The Right ◽  
In Pregnancy

Congenital Heart Diseases (CHD) lead to various changes in the normal mechanisms of hemodynamics. Pregnancy in women with CHDs is rare. Double Outlet Right Ventricle (DORV) is a rare disorder, in which both the aorta and the pulmonary artery arise from the right ventricle. We present a case of a thirty-year-old pregnant woman who presented to us with 22 weeks of amenorrhea. She had DORV with VSD, which was undiagnosed till she came to our hospital. Double Outlet Right Ventricle (DORV) is a rare congenital heart disease. Pregnancy in a patient with DORV needs early diagnosis and a stepwise multidisciplinary approach for successful outcomes.

Chance and Ventricular Septal Defect

PEDIATRICS ◽  
1986 ◽  
Vol 77 (6) ◽  
pp. 930-931
Author(s):  
JAMES J. NORA
Keyword(s):  
Ventricular Septal Defect ◽  
Congenital Heart Defect ◽  
Genetic Predisposition ◽  
Congenital Heart ◽  
Septal Defect ◽  
Heart Diseases ◽  
Large Element ◽  
Congenital Heart Diseases ◽  
Multifactorial Inheritance ◽  
New Hypothesis

To the Editor.— Newman1 has restated the multifactorial inheritance hypothesis of the etiology of congenital heart diseases to emphasize the element of chance (which is, of course, inherent in the hypothesis) and proposes what he considers to be a new hypothesis. There is, of course, a very large element of chance in multifactorial inheritance for an individual with a genetic predisposition to ventricular septal defect or other congenital heart defect also to have a genetic predisposition to an environmental teratogen and finally to have these two predispositions triggered during the very short vulnerable period of cardiogenesis (approximately 1 month or less in duration for most lesions).

Congenital Heart Diseases in Swine

1982 ◽  
Vol 19 (6) ◽  
pp. 676-686 ◽  
Author(s):  
F. S. Hsu ◽  
S. J. Du
Keyword(s):  
Congenital Heart ◽  
Septal Defect ◽  
Heart Diseases ◽  
Congenital Heart Diseases ◽  
Cardiac Malformation ◽  
Atrioventricular Canal ◽  
Large White ◽  
Cardiac Anomalies ◽  
Congenital Cardiac Anomalies ◽  
Crossbred Pigs

One hundred twenty-two congenital cardiac anomalies were diagnosed in 83 pigs (4.35%) during necropsies of 1906 pigs from one day to four years of age during an 11-month period. The incidence of cardiac malformation was highest at 29 to 56 days of age. Of the 83 pigs with cardiac anomalies, 47 (56%) were male and 36 (44%) were female, and of these, 15 (18%) were purebred and 68 (82%) were crossbred pigs. Of the 15 purebred pigs with cardiac malformation, there were seven Landrace pigs, four Large White pigs, three Duroc Jersey pigs, and one Yorkshire pig; whereas 94% of the 68 crossbred pigs were crossbred among Landrace, Duroc Jersey, and Large White. The 122 cardiac anomalies found in the 83 pigs were: dysplasia of the tricuspid valve in 42 pigs, atrial septal defect in 31 pigs, subaortic stenosis in 22 pigs, ventricular septal defect in nine pigs, persistent common atrioventricular canal in eight pigs, malformation of the moderator band in seven pigs, persistent vena cava in one pig, persistent truncus arteriosus in one pig, and pulmonary stenosis in one pig. The pathological features of the anomalies in swine were similar to those described in small animals and in man. The findings indicate that spontaneous porcine cardiac anomalies might provide models for cardiovascular investigators to study the etiology and pathogenesis of congenital heart diseases in man and other mammals.

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