scholarly journals Asphyxiation by inhaling the inert gas helium inside a plastic bag

2017 ◽  
pp. 91-92
Author(s):  
Volodymyr Shilan ◽  
Cyril Shilan ◽  
Oleksii Shalniev
Keyword(s):  
Forensic Toxicology ◽  
Venous Congestion ◽  
The Other ◽  
Inert Gas ◽  
Post Mortem ◽  
Interstitial Edema ◽  
Internal Organs ◽  
Arterial Blood ◽  
Blood Filling ◽  
Plastic Bag

А case of death from asphyxiation by inhaling the inert gas helium inside a plastic bag placed over the head. Findings and discussion. In our practice, we had a case of post-mortem examination of a 22 y.o. male. As it is known from the circumstances of the case, the mail corpse was found in a forest belt area, with his head inside a black plastic bag tight-fitted around his neck with a band. In the bag, there were two plastic tubes – one of them was placed obliquely at the level of right anterior surface of neck and was fixed to the neck with transparent adhesive tape. The other end of tube was connected to the outlet of a valve on a cylinder of brown color superscribed «HELIUM». The valve of a cylinder was opened. The other tube is located on the left side of the neck, with a rubber ball attached to the exposed end. On post-mortem examination, we found the following: face – pale, not congested, w/o petechiation; livor mortis – generalized dark purple discoloration of the skin. Findings on internal examination: congestion of internal organs; dark-red liquid blood inside the cardiac cavity and larger vessels; hemicardiadextra, SVC and IVC overfilled with blood. No hemorrhages under epicardium and pleura. Findings during microscopic examination of internal organs: Heart: lack of arterial blood, venous congestion. Albuminous degeneration of cardiomyocytes. Interstitial edema. Areas of dystelectasis, acute vesicular emphysema. Pulmonary congestion. Liver: irregular blood filling of tissue. Albuminous degeneration, destruction of hepatocellular cytoplasm. Interstitial edema. Kidney: cortical ischemia, congestion of straight venules. Albuminous degeneration in nephrothelium of convoluted tubules. Interstitial edema. Brain: irregular blood filling of cerebral vessels. In pia mater: edema&focal infiltrates of fresh RBCs. Focal voids surrounding the vessels and neurons. Ischemic degeneration of neurons. Red blood cells accumulations in the enlarged paravasal spaces. Suprarenal gland: irregular venous congestion of tissue; occasional thinning of adrenal cortex. Pancreatic gland: lack of arterial blood, venous congestion. Spleen: irregular blood filling of tissue. Decision: morphological signs of acute death. Pulmonary edema. Forensic toxicology test results: methyl, ethyl, isopropyl, butyl, isoamyl alcohol; barbiturates; opium alkaloids – morphine, codeine and their synthetic analogues; phenothiazine, benzodiazepine derivatives; ephedrine, ephedrone – have not been identified. Conclusion: As can be seen from the above, the results of forensic examination of corpse, forensic toxicology and forensic histology tests, with account being taken of circumstances and scene investigation details, allowed suggesting that the possible cause of death was the asphyxiation by inhaling the inert gas helium inside a plastic bag placed over the head.

scholarly journals VIII. On the descending degenerations which follow lesions of the gyrus marginalis and gyrus fornicatus in monkeys

1889 ◽  
Vol 180 ◽  
pp. 331-354
Keyword(s):  
The Other ◽  
Post Mortem ◽  
Cerebral Lesions ◽  
Series Of Experiments ◽  
The Government ◽  
Government Grant

The following paper contains the record of an investigation into the degenerations which follow lesions of the gyrus marginalis and gyrus fornicatus in Monkeys. The work has been carried on under my direction by Mr. France, with the aid of a grant from the Government Grant Fund, and represents part of a long investigation into the degenerations which follow artificially produced cerebral lesions, the material for which has been furnished by cases operated upon in conjunction respectively with Professor V. Horsley and Dr. Sanger Brown. These cases and the physiological results of the operations have already been published in the ‘Philosophical Transactions.’ The experiments here dealt with, twelve in number, comprise only the lesions of the gyrus marginalis and gyrus fornicatus, and, with one exception (case 12), are taken from the series of experiments performed in conjunction with Mr. Horsley. Of the twelve cases, six were of removal, or attempted removal, of the gyrus marginalis, and six of removal, or attempted removal, of the gyrus fornicatus. But in only one or two instances was the lesion, as determined by post-mortem examination, exactly limited to the convolution which it was attempted to remove, for in most cases the adjacent gyrus was to a certain extent involved in the injury. This was especially the case when removal of the gyrus fornicatus had been attempted, on account of its deep situation, and the difficulty of getting at it without some manipulation of the superjacent gyrus. Nevertheless, the removal of one or the other gyrus was sufficiently complete in all the cases here selected to produce characteristic symptoms and characteristic descending degenerations.

External bleeding versus dermal pocketing for distal digital replantation without venous anastomosis

2018 ◽  
Vol 44 (2) ◽  
pp. 181-186 ◽  
Author(s):  
Rebecca Lim ◽  
Ellen Lee ◽  
Joel Lim ◽  
Alphonsus K. S. Chong ◽  
Sandeep J. Sebastin ◽  
...  
Keyword(s):  
Venous Congestion ◽  
The Other ◽  
Small Study ◽  
Level Of Evidence ◽  
Venous Anastomosis ◽  
Digital Replantation ◽  
Better Than

Venous congestion in distal digital replantations is a common problem as suitable veins are not always available. We compared two methods of venous decongestion, external bleeding ( n = 15) and dermal pocketing ( n = 28) carried out when venous anastomosis was not possible. The findings of this small study suggest that neither method of venous decongestion is clearly better than the other. Level of evidence: IV

Estimation of ventilation-perfusion inequality by inert gas elimination without arterial sampling

1985 ◽  
Vol 59 (2) ◽  
pp. 376-383 ◽  
Author(s):  
P. D. Wagner ◽  
C. M. Smith ◽  
N. J. Davies ◽  
R. D. McEvoy ◽  
G. E. Gale
Keyword(s):  
Cardiac Output ◽  
Venous Blood ◽  
Inert Gas ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease ◽  
Arterial Access ◽  
Arterial Blood ◽  
Potential Applications ◽  
Clinical Interest ◽  
Mixed Venous

Estimation of ventilation-perfusion (VA/Q) inequality by the multiple inert gas elimination technique requires knowledge of arterial, mixed venous, and mixed expired concentrations of six gases. Until now, arterial concentrations have been directly measured and mixed venous levels either measured or calculated by mass balance if cardiac output was known. Because potential applications of the method involve measurements over several days, we wished to determine whether inert gas levels in peripheral venous blood ever reached those in arterial blood, thus providing an essentially noninvasive approach to measuring VA/Q mismatch that could be frequently repeated. In 10 outpatients with chronic obstructive pulmonary disease, we compared radial artery (Pa) and peripheral vein (Pven) levels of the six gases over a 90-min period of infusion of the gases into a contralateral forearm vein. We found Pven reached 90% of Pa by approximately 50 min and 95% of Pa by 90 min. More importantly, the coefficient of variation at 50 min was approximately 10% and at 90 min 5%, demonstrating acceptable intersubject agreement by 90 min. Since cardiac output is not available without arterial access, we also examined the consequences of assuming values for this variable in calculating mixed venous levels. We conclude that VA/Q features of considerable clinical interest can be reliably identified by this essentially noninvasive approach under resting conditions stable over a period of 1.5 h.

scholarly journals Trypanosoma cruzi meningoencephalitis and myocarditis in a patient with acquired immunodeficiency syndrome

1993 ◽  
Vol 35 (2) ◽  
pp. 205-208 ◽  
Author(s):  
Ademir Rocha ◽  
Marcelo S. Ferreira ◽  
Sergio A. Nishioka ◽  
Marcos Silva ◽  
Marcius K. N. Burgarelli ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
Differential Diagnosis ◽  
Chagas Disease ◽  
Acquired Immunodeficiency Syndrome ◽  
The Other ◽  
Post Mortem ◽  
Immunodeficiency Virus ◽  
Acquired Immunodeficiency ◽  
Immunodeficiency Syndrome ◽  
Male Heterosexual

We report the case of a 52-year-old male heterosexual patient with acquired immunodeficiency syndrome (AIDS) and reactivation of Chagas' disease manifested by meningoencephalitis and myocarditis, diagnosed post-mortem. Unexplained reactivation of Chagas' disease should be included among the diagnostic criteria of AIDS in human immunodeficiency virus positive patients. On the other hand, AIDS should be considered in the differential diagnosis of patients with unexplained reactivation of Chagas' disease.

Validation of measurements of ventilation-to-perfusion ratio inequality in the lung from expired gas

2003 ◽  
Vol 94 (3) ◽  
pp. 1186-1192 ◽  
Author(s):  
G. Kim Prisk ◽  
Harold J. B. Guy ◽  
John B. West ◽  
James W. Reed
Keyword(s):  
Gas Exchange ◽  
Respiratory Exchange Ratio ◽  
Blood Gases ◽  
Inert Gas ◽  
Phase Iii ◽  
Strongly Correlated ◽  
Arterial Blood Gases ◽  
Arterial Blood ◽  
Expired Gas ◽  
The Relationship

The analysis of the gas in a single expirate has long been used to estimate the degree of ventilation-perfusion (V˙a/Q˙) inequality in the lung. To further validate this estimate, we examined three measures ofV˙a/Q˙ inhomogeneity calculated from a single full exhalation in nine anesthetized mongrel dogs under control conditions and after exposure to aerosolized methacholine. These measurements were then compared with arterial blood gases and with measurements of V˙a/Q˙ inhomogeneity obtained using the multiple inert gas elimination technique. The slope of the instantaneous respiratory exchange ratio (R slope) vs. expired volume was poorly correlated with independent measures, probably because of the curvilinear nature of the relationship due to continuing gas exchange. When R was converted to the intrabreathV˙a/Q˙ (iV˙/Q˙), the best index was the slope of iV˙/Q˙ vs. volume over phase III (iV˙/Q˙slope). This was strongly correlated with independent measures, especially those relating to inhomogeneity of perfusion. The correlations for iV˙/Q˙ slope and R slope considerably improved when only the first half of phase III was considered. We conclude that a useful noninvasive measurement ofV˙a/Q˙ inhomogeneity can be derived from the intrabreath respiratory exchange ratio.

Causes of bradycardia with static respiratory hypoxia in athletes

2021 ◽  
Vol 11 (1) ◽  
pp. 30-36
Author(s):  
Yu. E. Vaguine
Keyword(s):  
Heart Rate ◽  
Standard Deviation ◽  
Arterial Oxygen Saturation ◽  
The Other ◽  
Arterial Oxygen ◽  
Breath Holding ◽  
Basketball Players ◽  
Heart Rate Monitor ◽  
Arterial Blood

According to some literature data, during voluntary long-term breath holding (BH), the heart rate (HR) increases, and according to others, it decreases.Objective: to determine the psychophysiological parameters that cause a change in HR during BH in athletes with different resistance to respiratory hypoxia.Materials and methods: HR at BH was studied in 14 beginner athletes, 15 basketball players and 12 swimmers-divers. Duration of BH was recorded. The HR was recorded on a heart rate monitor. After recording an electrocardiogram, the standard deviation of the duration of cardiac cycles was calculated. The arterial oxygen saturation was measured with a pulse oximeter. The statistically significant values of the correlation coefficient (r) were ≥0.33 with p < 0.05.Results: it was found that out of 41 sportsmen, HR increased by more than 5 % in 4, changed insignificantly in 7 and decreased by less than 5 % in 30. Beginner athletes had tachycardia, and BH was quickly interrupted by an imperative inhalation. The saturation of arterial blood with oxygen did not change and did not affect the change in HR. The decrease in heart rate in swimmers-divers in comparison with the other two groups of people examined was statistically significant (p < 0.05). The duration of BH had a direct correlation (r = 0.5) with bradycardia in these people. The duration of BH caused (r = 0.8) hypoxia, the value of which also directly influenced (r = 0.38) the severity of bradycardia. In addition, the decrease in HR depended on high HR (r = 0.36) and low HR variability (r = 0.38) before BH.Conclusion: tachycardia occurs in beginner athletes who experience discomfort with BH. Bradycardia occurs in sportsmen with a long-term BH setting without discomfort. Sympathicotonia in the prelaunch state predetermines the severity of bradycardia in BH. The duration of BH and the resulting hypoxia provide the occurrence of bradycardia.

JUSTIFICATION OF VETERINARY AND SANITARY ASSESSMENT OF WILD AND DOMESTIC DUCKS AT SARCOCYSTOSIS

2019 ◽  
Vol 1 (1) ◽  
pp. 6-12
Author(s):  
I. G. Seregin ◽  
◽  
Yu. V. Petrova ◽  
S. V. Redkin ◽  
Yu. G. Isaev ◽  
...  
Keyword(s):  
The Other ◽  
Internal Organs ◽  
Domestic Ducks ◽  
Wild Duck ◽  
Central Russia ◽  
Physico Chemical ◽  
Muscle Lesions ◽  
Canning Industry ◽  
Microbiological Indicators

The article presents the results of studies of carcasses of domestic and wild ducks for the purpose of detection of sarcocystosis. The commodity, organoleptic, physico-chemical, microbiological indicators of the meat of sick and healthy domestic and wild ducks were determined. Researches were carried out in spring and autumn in the farms of six regions of Central Russia, on the territory of which there were large reservoirs (ponds, lakes or swamps). The intensity of the destruction of wild ducks by sarcocystosis was high, of domestic ducks was medium. Sarcocystis one wild duck found in large quantity in the chest muscles and lower in the muscles of the neck, the other two (domestic and wild) affected ducks Sarcocystis was discovered in many skeleton, which muscles. In chest muscles of one wild duck sarcocystis has revealed in large quantity and lower in the muscles of the neck, sarcocystis was discovered in many muscles of skeleton of the other two (domestic and wild) affected ducks. The size of the sarcocystosis was different, but no more than the millet grain. In our opinion, in cases of intense muscle lesions with sarcocistosis, carcasses and poultry organs should be sent for disposal or fed to animals after stripping and boiling for at least 1 hour. At weak injury and the absence of dystrophic processes in the muscles of the carcass, their internal organs are cleaned and sent to the canning industry. It is not allowed to feed infected sarcocistosis raw bird meat to dogs, cats and other carnivores.

Mechanism of circulatory responses to systemic hypoxia in the anesthetized dog

1965 ◽  
Vol 209 (2) ◽  
pp. 397-403 ◽  
Author(s):  
Hermes A. Kontos ◽  
H. Page Mauck ◽  
David W. Richardson ◽  
John L. Patterson
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Cardiac Output ◽  
Vascular Resistance ◽  
The Other ◽  
Arterial Flow ◽  
Arterial Blood ◽  
Systemic Hypoxia ◽  
Anesthetized Dogs ◽  
Spontaneously Breathing

The possibility that mechanisms secondary to the increased ventilation may contribute significantly to the circulatory responses to systemic hypoxia was explored in anesthetized dogs. In 14 spontaneously breathing dogs systemic hypoxia induced by breathing 7.5% oxygen in nitrogen increased cardiac output, heart rate, mean arterial blood pressure, and femoral arterial flow, and decreased systemic and hindlimb vascular resistances. In 14 dogs whose ventilation was kept constant by means of a respirator pump and intravenous decamethonium, systemic hypoxia did not change cardiac output, femoral arterial flow, or limb vascular resistance; it significantly decreased heart rate and significantly increased systemic vascular resistance. In seven spontaneously breathing dogs arterial blood pCO2 was maintained at the resting level during systemic hypoxia. The increase in heart rate was significantly less pronounced but the other circulatory findings were not different from those found during hypocapnic hypoxia. Thus, mechanisms secondary to increased ventilation contribute significantly to the circulatory responses to systemic hypoxia. Hypocapnia accounts partly for the increased heart rate, but not for the other circulatory responses.

Arterial blood gases in man during inert gas narcosis.

1974 ◽  
Vol 36 (1) ◽  
pp. 45-48 ◽  
Author(s):  
P B Bennett ◽  
G D Blenkarn
Keyword(s):  
Blood Gases ◽  
Inert Gas ◽  
Arterial Blood Gases ◽  
Arterial Blood

Central infusion of vasopressin decreased plasma vasopressin concentration in dogs

1982 ◽  
Vol 243 (5) ◽  
pp. E365-E369
Author(s):  
B. C. Wang ◽  
L. Share ◽  
J. T. Crofton
Keyword(s):  
Cerebrospinal Fluid ◽  
Physiological Role ◽  
The Other ◽  
Intracerebroventricular Infusion ◽  
Arterial Blood ◽  
Plasma Vasopressin ◽  
Severe Hemorrhage ◽  
Anesthetized Dogs ◽  
Vasopressin Secretion ◽  
Hypertonic Saline Infusion

The effects of increasing the cerebrospinal fluid (CSF) vasopressin concentration (CSFADH) by intracerebroventricular infusion of vasopressin on the plasma vasopressin concentration (PADH) were studied in four groups of anesthetized dogs. One group received an intracerebroventricular infusion of artificial CSF (ACSF) alone for 90 min; the other groups were infused intracerebroventricularly with vasopressin at rates of 10, 20, or 50 microunits/min for 90 min. Arterial blood and CSF samples were taken just before infusion and at 30-min intervals for 210 min. Vasopressin infused intracerebroventricularly at 10, 20, and 50 microunits/min resulted in peak CSFADH of 32.2 +/- 5.3, 82.6 +/- 4.5, and 131.4 +/- 12.5 microunits/ml and reductions in PADH of 32, 47, and 51%, respectively. Only the latter two responses were significant (P less than 0.5-0.01). Because the peak increases in CSFADH after intracerebroventricular infusion of vasopressin ranged from values that were similar to or five times higher than those seen after severe hemorrhage or intracerebroventricular hypertonic saline infusion, we suggest that centrally acting vasopressin may play a physiological role in control of vasopressin secretion.

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