Neutrophil-Lymphocyte Ratio and Procalcitonin as Predictors of the Severity of Acute Pancreatitis

Author(s):  
Dessy Iriana ◽  
Ani Kartini ◽  
Yuyun Widaningsih ◽  
Agus Alim Abdullah

The Neutrophil-Lymphocyte Ratio (NLR) and procalcitonin are used to indicate systemic inflammation in variousmedical disorders. Both parameters were determined in this study to predict the severity of acute pancreatitis. This studywas a cross-sectional study using a retrospective approach to patients diagnosed with acute pancreatitis by using medicalrecord data from patients at Dr. Wahidin Sudirohusoso Hospital, Makassar, from January 2014 to May 2019. This studycomprised 35 patients hospitalized with acute pancreatitis, with a similar proportion of males and females. This studydiscovered that the mean age in this study was 44.17±12.9 years. The most prevalent cause was Gallstones (77.1%), themost severe degree was mild (54.2%), and the highest outcome was survival (77.1%). The NLR (9.93±11.19, p=0.011)increased in proportion to severity. However, additional analysis based on classification of disease severity revealed thatonly mild-severe NLR was significant (p=0.005). Procalcitonin (8.13±11.25, p=0.001) increased along with the increaseddisease severity, and the subsequent analysis showed that the distribution of severity was similar. The NLR can predict theseverity of acute pancreatitis but is less effective than procalcitonin. This study required a more proportional subjectpopulation and consideration of other factors.

2004 ◽  
Vol 27 (2) ◽  
pp. 137-142 ◽  
Author(s):  
Hung-Huey Tsai

This cross-sectional study investigated mandibular developmental changes in untreated normal Taiwanese from the deciduous to permanent dentition. Differences in the mean values for ramus height and body length between males and females were statistically significant after eruption of the permanent second molars. SNB angles significantly increased and gonial and L1-MP angles significantly decreased from deciduous to permanent dentition in both sexes. The SN-MP angle in females significantly decreased and ramus inclination in males significantly increased from the early mixed to permanent dentition.


2013 ◽  
Vol 53 (6) ◽  
pp. 350
Author(s):  
Naomi Riahta ◽  
Muhammad Ali ◽  
Bistok Saing ◽  
Yazid Dimyati ◽  
Johannes Saing

Background Headaches are common problems in adults,adolescents, and children. Headaches impact a child's life, theirfamily life, and even society. An assessment of quality of life inadolescents with primary headaches may help to determine actionsnecessary to improve the quality of life of these patients.Objective To assess the quality oflife of adolescents with primaryheadach es compared to healthy adolescents.Methods We conducted a cross-sectional study in December2009 on adolescents aged 13 to 18 years. The headache groupconsisted of children with primary headaches according to theInternational Classification of Headache Disarders and the controlgroup consisted of healthy adolescents. Subjects were selected byconsecutive sampling, with 75 subjects in each group. Subjectsfilled the Pediatric Quality of Life Inventary version 4.0 (PedsQL4.0) questionnaire.Results The mean PedsQL total score was significantly lowerin the headache group than in the contra 1 group [ l 7 5. 7 vs.392.2, respectively, (95%CI of differences -28.l to -219.3, P =0.001)]. However, out of23 items in the questionnaire, 9 werenot significantly different between the headache and controlgroups.Conclusions Primary headaches in adolescents is associatedwith lower quality of life. Most quality of life domains scoresare significantly lower in adolescents with primary headachescompared to those without primary headaches.


2015 ◽  
Vol 27 (3) ◽  
pp. 247-251 ◽  
Author(s):  
Bridget Omisore ◽  
Akinlolu G. Omisore ◽  
Emmanuel Akintunde Abioye-Kuteyi

Abstract Background: Adolescents are in their formative years, and they experience several changes including anthropometric changes. Significant weight gain occurs in adolescence, and increasingly, obesity and consequent increase in blood pressure (BP) are found in adolescents. Objective: This study compared anthropometric and BP measurements in male and female adolescents. Methods: A cross-sectional study of 1000 adolescents (510 males and 490 females) were selected by multi-stage sampling from eight secondary schools. Pertinent information was collected with the aid of a structured questionnaire, anthropometric and blood pressure measurements. Data were analyzed using SPSS 16.0 version, and the means of anthropometric indices and blood pressures in males and females were compared using independent t-test. Results: The mean age for male respondents was 13.83 years (SD 2.12) and for females 13.62 (SD 1.96). Generally, anthropometric indices gradually increased from the lower ages to the higher ages in both males and females. The mean height was the same for both males and females (1.54 m), while the mean weight, body mass index (BMI), and waist circumference were significantly higher in females than in males (p<0.05). A significantly higher proportion of females compared with males were overweight (10.2%, 5.3%) and obese (3.9%, 2.0%), respectively. The overall prevalence of “hypertension,” was 4.1% and more females (70.7%) had “hypertension” than males (29.3%). Conclusion: Females were heavier and constituted the greater proportion of those who had elevated BP. Adequate attention needs to be given to the challenging problems of overweight and obesity to forestall development of hypertension in adolescents, especially female adolescents.


2015 ◽  
Vol 27 (1) ◽  
pp. 4-7
Author(s):  
Rehena Parvin ◽  
Md Naushad Ali ◽  
ASQ Md Sadeque ◽  
AS Mohiuddin ◽  
Nazmun Nahar

This cross sectional study was carried out in the department of Radiology & Imaging, BIRDEM, Dhaka, from January 2012 to December 2012 to find out the sensitivity of thickened renal fascia in diagnosis of acute pancreatitis at CT. Total 50 patients (mean age was 41.64 years with range from 18 to 65 years, 34M/ 16F) with clinical suspicion of acute pancreatitis included in this study after analyzing selection criteria. Total 32(64%) of the 50 clinically suspected cases were diagnosed as acute pancreatitis according to the criteria mentioned in material and methods. The mean thickness of renal fascia in acute pancreatitis was 7.20 ± 3.32 mm (mean±SD) with range from 1 to 13 mm and maximum 18(40%) patients were found having thickened fascia within 4.0 to 6.9 mm. The extension of acute panceatitis only in left side was 71.8%. In 21.8%, the extension was bilateral. In 3.1% the renal fascial thickening was present on right side only .In the remaining 3.1%, renal fascia was not thickened.In 31 (96.8%) patients, the process extended into the anterior pararenal space. Both anterior and posterior renal fascia thickening was observed in 2(6.2%) patients. Normal thickness of renal fascia was found in 1(3.1%) patient. Sensitivity of thickened renal fascia in diagnosis of acute pancreatitis at CT was found 97%, specificity 50%, accuracy 80%, positive predictive value77%, negative predictive value 90%.It can be concluded that renal fascia thickening is an important as well as sensitive (97%) CT feature in the diagnosis of acute pancreatitis.Medicine Today 2015 Vol.27(1): 4-7


2021 ◽  
Vol 9 (1) ◽  
pp. 87-87

n the article entitled “Study on Neutrophil Lymphocyte ratio and Platelet lymphocyte ratio in COVID-19 from our prospective -A cross sectional study” published in the Volume 8, Issue 3, September- December 2020 issue of the Perspectives In Medical Research ,[1] the author’s sequence and affiliation is incorrectly written. The correct sequence is as under. 1. Syed Imran Ali, Assistant Professor, Department of Physiology, Mamata Academy of Medical Sciences 2. Farha Tarannum, Assistant Professor, Department of Community medicine, Mamata Academy of Medical Sciences 3. Rubiya Khan, Assistant Professor, Department of Pathology, Mamata Academy of Medical Sciences 4. M Kanya Kumari, Professor, Department of Pathology, Mamata Academy of Medical Sciences 5. Mujahid Mohammed, Associate Professor, Department of Physiology, Mamata Academy of Medical Sciences 6. Mohammed Asghar Ali, Professor, Department of Physiology, Mamata Academy of Medical Sciences Corresponding author: Syed Imran Ali, Assistant Professor, Department of Physiology, Mamata Academy of Medical Sciences


2015 ◽  
Vol 09 (03) ◽  
pp. 394-399 ◽  
Author(s):  
Aby Abraham ◽  
Jinu George ◽  
Elbe Peter ◽  
Koshi Philip ◽  
Rajesh Chankramath ◽  
...  

ABSTRACT Objective: The present study is intended to add a new parameter that would be useful in orthodontic clinical evaluation, treatment planning, and determination of vertical dimension (at occlusion). Materials and Methods: Standardized videographic recording of 79 subjects during posed smile was captured. Each video was then cut into 30 photos using the free studio software. The widest commissure-to-commissure posed smile frame (posed smile width [SW]) was selected as one of 10 or more frames showing an identical smile. Lower third of the face is measured from subnasale to soft tissue menton using a digital vernier caliper. Two values were then compared. Ratio between lower facial height and posed SW was calculated. Results: The co-relation between smiling width and lower facial height was found to be statistically significant (P < 0.01). The ratio of lower facial height and smiling width was calculated as 1.0016 with a standard deviation (SD) = 0.04 in males and 1.0301 with an SD = 0.07 in females. The difference between the mean lower facial height in males and females was statistically significant with a t = 10.231 and P = 0.000. The difference between the mean smiling width in males and females was also statistically significant with a t = 5.653 and P = 0.000. Conclusion: In class I subjects with pleasing appearance, normal facial proportions, normal overjet and overbite, and average Frankfort mandibular angle, the lower facial height (subnasale to soft tissue menton) is equal to posed SW.


Author(s):  
Sneha Barkur Sadashiva ◽  
KS Chenthil

Introduction: There have been various inflammatory markers implicated in the pathogenesis of Acute Coronary Syndromes (ACS). However, the role of the Neutrophil Lymphocyte Ratio (NLR) and Platelet Lymphocyte Ratio (PLR) as prognostic markers in ST-elevation Myocardial Infarction (STEMI) remains poorly researched. Aim: To determine the prognostic value of NLR and PLR to predict the immediate outcomes in patients with acute STEMI, and if any association exists between NLR/PLR and Thrombolysis in Myocardial Infarction (TIMI) risk score. Materials and Methods: This was a cross-sectional study conducted at a tertiary care centre, Puducherry, India, where 190 patients who presented to casualty with STEMI were enrolled. The patient co-morbidities, personal and family history were obtained. The routine laboratory parameters including platelets, lymphocytes, neutrophils and their corresponding ratios were calculated. Patients were grouped into low and high NLR/PLR groups and were assessed for occurrence of in-hospital mortality or Major Adverse Cardiovascular Events (MACE). Analysis was made to see if there is an association between NLR/PLR and MACE. Chi-square test and one-way ANOVA test was used for statistical significance. Results: Among 190 subjects, 157 male and 33 female with mean age of 55.72±11.24 years were included. A total of 8.94% patients 8.94% had MACE. NLR was positively associated with MACE (p-value=0.0006), whereas PLR was not associated with MACE. Patients with high NLR had 1.45 times higher odds of having MACE. NLR was significantly associated with TIMI risk score. Both NLR (F ratio=6.341) and PLR (F ratio=4.600) showed significant association with Killip classification, however NLR showed higher association (p-value <0.001). Conclusion: NLR can be used as a powerful prognostic marker for predicting immediate MACE and death in STEMI patients. In addition, NLR showed positive correlation with Killip classification and TIMI risk score.


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