Clinical Case: SARS-CoV-2 Reactivation After a Heavy Workout

2020 ◽  
Vol 47 (3) ◽  
pp. 38-40
Author(s):  
S. Marchev ◽  
N. Hadzhimineva ◽  
A. Simidchiev

AbstractWe present a clinical case of a patient with reactivation of SARS-CoV-2 infection after strenuous exercise in the gym. Reactivation of the virus was confirmed after detecting SARS-CoV-2 in a nasopharyngeal swab sample using real-time polymerase chain reaction (PCR). The clinical symptoms of the patient – fever and shortness of breath, as well as the presence of IgM antibodies further confirmed the diagnosis. The subjective complaints of persistent shortness of breath for more than a few weeks were noted.

2021 ◽  
Vol 9 ◽  
pp. 2050313X2110666
Author(s):  
Nithya Rajendran ◽  
Puteri Maisarah Rameli ◽  
Grace Collins

A 25-year-old woman with a background history of bronchial asthma and intellectual disability presented to hospital with progressively worsening dyspnoea. Despite testing negative four times for coronavirus disease infection by nasopharyngeal swab reverse-transcriptase polymerase chain reaction, her clinical symptoms of hypoxaemic respiratory failure and radiological findings on computed tomography pulmonary angiogram were consistent with coronavirus disease pneumonia. Although she made a quick recovery in the intensive care unit with a combination of empirical antibiotics, corticosteroids, high flow nasal oxygen, therapeutic anticoagulation and awake semi proning, her protracted hospital course due to persistent sinus tachycardia remained challenging. A diagnosis of potential postural orthostatic tachycardia syndrome was explored during the acute phase of illness following an active stand test and exclusion of other causes. She was treated with beta blockers as she failed to improve with non-pharmacological measures. We searched for similar cases by analysing the literature databases. Our case aims to stress the importance of recognising and treating patients with negative nasal reverse-transcriptase polymerase chain reaction swabs as coronavirus disease infection, especially if there is strong evidence of clinical and radiological findings where diagnosis is often under recognised in asthmatics with intellectual disability.


2020 ◽  
Vol 73 (12) ◽  
pp. 2572-2575
Author(s):  
Marlena Kwiatkowska ◽  
Inga Chomicka ◽  
Jolanta Malyszko

Introduction: A novel coronavirus SARS-CoV-2 RNA, detected by reverse-transcription polymerase chain reaction (RT-PCR) was identified as the cause of a cluster of pneumonia cases in Wuhan, China. It rapidly spread, at first in China, then resulting in an epidemic in other countries throughout the world. One of such controversial topics is the issue of diagnostics and interpretation of test for COVID-19. According to Polish and global guidelines, the basis for diagnosis is molecular testing – real-time reverse transcriptasepolymerase chain reaction (RT-PCR). Taking all these data into consideration, the aim of the study was to compare RT-PCR with serological test in our employees post-exposure. According to Polish and global guidelines, the basis for diagnosis is molecular testing, real-time reverse transcriptase-polymerase chain reaction (RT-PCR). The aim: To compare RT-PCR with serological test in our employees post-exposure. Material and methods: 79 employees of the Clinic, 19 men and 60 women in the age range 27-69 years were evaluated. Tests were begun four days after information about the positive test in our „Employee 0” and lasted for 7 days. At first, we made RT-PCR tests on the specimen from nasopharyngeal swab. Then, we accomplished rapid antibodies tests. This test is based on the qualitative assessment of the presence of IgM and IgG antibodies by immunochromatography using a sample of capillary blood from the fingertip. Results: All the tests were negative. No employee developed symptoms during the 7-day follow-up after the end of the tests. Conclusions: As routine tests for patients have been implemented widely, but similar solutions for employees have not gained popularity. Use of personal protective equipment (PPE) e.g. facemask and shields, transparent screens, disposable medical uniforms, minimalization the contact time, increasing distance from both colleagues and patients (if possible), and strictly follow sanitary procedures largely contributed to the absence of illness in the surveyed group of employees.


2021 ◽  
Vol 28 (05) ◽  
pp. 742-748
Author(s):  
Nadeem Ahmed Sheikh ◽  
Faiza Khanum ◽  
Erum Pervaiz ◽  
Kanwal Nadeem

Objectives: To evaluate deleterious impact of novel coronavirus infection 2019 (COVID-19), on both maternal and fetal well being during pregnancy. Study Design: Hospital-Based Cross-sectional Survey. Setting: Department of Gynecology & Obstetrics, Combined Military Hospital, Chiltan Road, Quetta (Balochistan); Department of Gynecology & Obstetrics, Frontier Corps Hospital, Quetta Cantonment (Balochistan), and the Department of Otorhinolaryngology (ENT), Combined Military Hospital, Chiltan Road, Quetta (Balochistan). Period: March 2020 till July 2020. Material & Methods: Careful history, clinical and obstetrical examination radiology and real time polymerase chain reaction of nasopharyngeal swab were carried out in pregnant patients presenting for childbirth. Deliveries were conducted through spontaneous vaginal birth and caesarean section as per indication. Neonatal evaluation and nasopharyngeal swab for COVID-19 real time polymerase chain reaction in all delivered fetuses were performed. Results: 516 pregnant women underwent spontaneous vaginal delivery and caesarean sections at these hospitals during the study duration. 4.06% (n=21) were confirmed as COVID-19 infected. All of the fetuses born to these infected mothers were delivered healthy and COVID-19 negative, except for one preterm fetus born at 22nd week of gestation on account of maternal gestational hypertension. Conclusion: Trans-placental spread of COVID-19 infection to the fetus is unlikely. However, the infection places a pregnant mother at much higher risk to develop complications which may occasionally lead to adverse pregnancy outcome.


2006 ◽  
Vol 175 (4S) ◽  
pp. 485-486
Author(s):  
Sabarinath B. Nair ◽  
Christodoulos Pipinikas ◽  
Roger Kirby ◽  
Nick Carter ◽  
Christiane Fenske

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