Efficacy of physical exercise program in patients with work-related knee osteoarthritis

Abstract Quality of life studies in patients with knee osteoarthritis (OA) attest to the significant impact of the disease on day-to-day activities and social interactions. The aim of this study was to assess the efficacy of a physical exercise program on functional status and quality of life in patients with work-related knee osteoarthritis. The present study included 144 participants with knee osteoarthritis, 72% women, mean age (SD) 47.2 (11.1) years. The patients were randomly assigned in two lots based on the type of kinetic treatment: lot A-with knee OA and medication (72 patients) and lot B- with knee OA, medication and exercise program (72 patients). They followed for 12 days ambulatory exercise programs based on increasing knee flexion, muscular strength and endurance, improving balance, coordination, and respiratory exercises. The patients in the control group continued their daily living activities. The evaluation was made at the beginning of the study (T0), after 2 weeks (T1) and 8 weeks after the 12 days of exercise program (T2) and was based on the following parameters: knee mobility (knee flexion), muscular strength, pain assessment on a Visual Analogue Scale (VAS), functional status (Western Ontario &McMaster Universities Osteoarthritis Index - WOMAC) and quality of life evaluation using SF-36 Questionnaire (36-Item Short Form Survey). Out of 144 participants who completed the initial evaluation, 138 also completed the 2 weeks and the 8 weeks follow-up assessments: 70 patients from the control lot and 68 patients from the exercise lot. The benefits of the kinetic programs were shown by a significant improvement in knee mobility and muscular strength for knee extensors (quadriceps muscle) and knee flexor muscles. Testing the linear correlations between the SF-36 score and the VAS (r=0.71, p<0.05) and WOMAC (r=0.83, p<0.05) indicators demonstrates a highly positive relationship between the quality of life expression, the pain assessment score and the functional status score in patients with knee OA. The physical exercise program improves both functional status and quality of life in patients with work-related knee osteoarthritis by increasing the range of motion and muscular strength and by reducing pain.

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Cardiovascular and Quality of Life Outcomes of a 3-Month Physical Exercise Program in Two Brazilian Communities

10.21203/rs.3.rs-27447/v1 ◽

2020 ◽

Cited By ~ 1

Author(s):

Marcelo Pereira de Lima ◽

Severo Conopca ◽

Renata Miyabara ◽

Geovanna Romeiro ◽

Luciana Aparecida Campos ◽

...

Keyword(s):

Quality Of Life ◽

Cardiovascular Risk ◽

Physical Exercise ◽

Exercise Program ◽

Density Lipoprotein ◽

Health Related Quality ◽

Sf 36 ◽

Related Quality ◽

Health Related

Abstract BackgroundA decline in physical activity levels in older people is related with worsening of quality of life and a lower cardiorespiratory fitness level, which are associated with cardiovascular disease events and mortality from all causes. Evidence supports the potential impact of community-based physical exercise programs (CEXE) on cardiovascular health and quality of life. The aim of this study was to investigate health-related quality of life (HRQoL) and cardiovascular risk factors of a CEXE in two communities in Brazil.MethodsAdults with an average age of 70.2 ± 5.4 years were recruited to take part in an individually designed group based CEXE program 2–3 times/ week (aerobic exercise, circuit resistance training and stretching exercises for 1 h each time). Once a week were held competitions to develop the socialization and the ability to collaborate among group members. A CEXE group was compared with a sedentary group. Cardiovascular outcomes were blood pressure (BP), triglycerides, body mass index, waist circumference, high-density-lipoprotein cholesterol (HDL-C), low-density-lipoprotein cholesterol (LDL-C), total cholesterol, and glycaemia. HRQoL was evaluated with the Short Form-36 (SF-36).ResultsOf the investigated cardiovascular outcome measures, significantly decreased by the CEXE program were systolic BP (5.7 [95%CI 0.2 to 11.3], p < 0.05), and the triglyceride-HDL-C ratio (0.8 [95%CI 0.05 to 1.5], p < 0.05), while HDL-C was significantly increased (4.4 [95%CI 0.02 to 8.8], p < 0.05). A significant improvement in the SF-36 subscales occurred in CEXE but not in the control group: physical functioning score (increase of 24.2 [95%CI 11.8 to 36.5] vs. -9.2 [95%CI -21.5 to 3.2], p < 0.001), physical role functioning score (increase of 35.4 [95%CI 12.8 to 58.0] vs. 16.7 [95%CI -6.0 to 39.3], p < 0.01) and general health score (increase of 23.7 [95%CI 36.9 to 10.4] vs. 2.4 [95%CI -10.9 to 15.7], p < 0.001).ConclusionThis study shows that a 12-week physical exercise program may significantly improve cardiovascular risk and health-related quality of life measures in older people. An important socio-cultural transferable strategy of our physical exercise program was to develop social activities during and outside the CEXE program.# These authors contributed equally to this study

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Monthly Disposable Income Is a Crucial Factor Affecting the Quality of Life in Patients with Knee Osteoarthritis

Healthcare ◽

10.3390/healthcare9121703 ◽

2021 ◽

Vol 9 (12) ◽

pp. 1703

Author(s):

Tian-Shyug Lee ◽

Hsiang-Chuan Liu ◽

Wei-Guang Tsaur ◽

Shih-Pin Lee

Keyword(s):

Quality Of Life ◽

Knee Osteoarthritis ◽

Short Form ◽

Demographic Characteristics ◽

Disposable Income ◽

Physical And Mental Health ◽

Knee Oa ◽

Bilateral Knee ◽

Sf 36

Knee osteoarthritis (OA) affects the quality of life (QOL) of elderly people; this study examines the demographic characteristics and QOL of patients with knee OA and identifies demographic characteristics that affect the QOL of these patients. In this cross-sectional study, 30 healthy controls and 60 patients with mild-to-moderate bilateral knee OA aged between 55 and 75 years were enrolled. All participants completed a questionnaire containing questions on 10 demographic characteristics and the Medical Outcome Study 36-Item Short-Form Health Survey (SF-36), and their QOL scores in the eight dimensions of the SF-36 were evaluated. In the OA group, significant correlations were observed between monthly disposable income and physical and mental health components. Monthly disposable income was found to considerably affect the QOL of patients with bilateral knee OA (i.e., it is a crucial factor affecting these patients). The findings of this study may provide a reference for formulating preventive strategies for healthy individuals and for future confirmatory research.

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Knee Osteoarthritis Injection Choices: Platelet- Rich Plasma (PRP) versus Hyaluronic Acid (A one-year randomized clinical trial)

Clinical Medicine Insights Arthritis and Musculoskeletal Disorders ◽

10.4137/cmamd.s17894 ◽

2015 ◽

Vol 8 ◽

pp. CMAMD.S17894 ◽

Cited By ~ 121

Author(s):

Seyed Ahmad Raeissadat ◽

Seyed Mansoor Rayegani ◽

Hossein Hassanabadi ◽

Mohammad Fathi ◽

Elham Ghorbani ◽

...

Keyword(s):

Quality Of Life ◽

Clinical Trial ◽

Hyaluronic Acid ◽

Knee Osteoarthritis ◽

Randomized Clinical Trial ◽

Platelet Rich Plasma ◽

Healing Process ◽

Knee Oa ◽

Sf 36

Introduction Knee osteoarthritis (OA) is the most common articular disease. Different methods are used to alleviate the symptoms of patients with knee OA, including analgesics, physical therapy, exercise prescription, and intra-articular injections (glucocorticoids, hyaluronic acid [HA], etc). New studies have focused on modern therapeutic methods that stimulate cartilage healing process and improve the damage, including the use of platelet-rich plasma (PRP) as a complex of growth factors. Due to the high incidence of OA and its consequences, we decided to study the long-term effect of intraarticular injection of PRP and HA on clinical outcome and quality of life of patients with knee OA. Method This non-placebo-controlled randomized clinical trial involved 160 patients affected by knee OA, grade 1–4 of Kellgren–Lawrence scale. In the PRP group ( n = 87), two intra-articular injections at 4-week interval were applied, and in the HA group ( n = 73), three doses of intra-articular injection at 1-week interval were applied. All patients were prospectively evaluated before and at 12 months after the treatment by Western Ontario and McMaster Universities Arthritis Index (WOMAC) and SF-36 questionnaires. The results were analyzed using SPSS 16.1 software (RCT code: IRCT2014012113442N5). Results At the 12-month follow-up, WOMAC pain score and bodily pain significantly improved in both groups; however, better results were determined in the PRP group compared to the HA group ( P < 0.001). Other WOMAC and SF-36 parameters improved only in the PRP group. More improvement (but not statistically significant) was achieved in patients with grade 2 OA in both the groups. Conclusion This study suggests that PRP injection is more efficacious than HA injection in reducing symptoms and improving quality of life and is a therapeutic option in select patients with knee OA who have not responded to conventional treatment.

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Demographic factors affecting the quality of life in patients with knee osteoarthritis

10.21203/rs.3.rs-783429/v1 ◽

2021 ◽

Author(s):

Tian-Shyug Lee ◽

Hsiang-Chuan Liu ◽

Wei-Guang Tsaur ◽

Shih-Pin Lee

Keyword(s):

Quality Of Life ◽

Knee Osteoarthritis ◽

Short Form ◽

Demographic Characteristics ◽

Disposable Income ◽

Physical And Mental Health ◽

Knee Oa ◽

Bilateral Knee ◽

Sf 36

Abstract Background Knee osteoarthritis (OA) affects the quality of life (QOL) of elderly people, this study examines the demographic characteristics and QOL of patients with knee OA and identifies demographic characteristics that affect the QOL of these patients. Methods In this cross-sectional study, 30 healthy controls and 60 patients with mild-to-moderate bilateral knee OA aged between 55 and 75 years were enrolled. All participants completed a questionnaire containing questions on 10 demographic characteristics and the Medical Outcome Study 36-Item Short-Form Health Survey (SF-36), and their QOL scores in the eight dimensions of the SF-36 were evaluated. Results In the OA group, significant correlations were observed between monthly disposable income and physical and mental health components. Monthly disposable income was found to considerably affect the QOL of patients with knee OA. Conclusion Monthly disposable income is a crucial factor affecting the QOL of patients with bilateral knee OA. The findings of this study may provide a reference for formulating preventive strategies for healthy individuals and for future confirmatory research. Trial registration: This study was approved by the Ethics Committee of Fu Jen Catholic University (FJU-IRB NO: C107179).

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Health-Related Quality of Life in Patients with Ankylosing Spondylitis: Relationship with Disease-Related Variables

Current Rheumatology Reviews ◽

10.2174/1573397115666191018162606 ◽

2020 ◽

Vol 16 (4) ◽

pp. 311-318 ◽

Cited By ~ 5

Author(s):

Gehan Elolemy ◽

Ahmed Aboughanima ◽

Sahar Ganeb ◽

Haytham Elziat

Keyword(s):

Quality Of Life ◽

Ankylosing Spondylitis ◽

Physical Health ◽

Disease Activity ◽

Functional Status ◽

Spinal Mobility ◽

Peripheral Arthritis ◽

Radiographic Severity ◽

Sf 36

Background: Ankylosing spondylitis (AS) is a chronic progressive inflammatory disease leading to functional limitations and subsequently impaired quality of life (QoL). Despite the fact that QoL was recognized as a significant perception, it was excluded from the core domains (defined by the Assessment of Spondyloarthritis International Society), because of ambiguity of measurement choice. Aim: To assess QoL in patients with AS using a generic; Short Form-36 (SF-36) and a diseasespecific; Ankylosing Spondylitis quality of life (ASQoL) instruments and to explore its relationship to the clinical characteristics, disease activity, functional status, and radiographic severity. Methods: A total of 47 AS patients who fulfilled modified New York criteria were included. Disease activity, functional status, spinal mobility, and radiographic severity were assessed by Bath AS Disease Activity Index (BASDAI), Bath AS Functional Index (BASFI), Bath AS Metrology Index (BASMI) and Bath AS Radiology Index (BASRI) respectively. SF-36 and ASQoL instruments evaluated Qol. Results: Physical health was more affected especially in patients with peripheral arthritis by SF-36 (p=0.008) and ASQoL (p=0.022) scores. Both SF-36 total and ASQoL scores correlated significantly with BASDAI (r = -0.329, p = 0.024 and r = 0.420, p = 0.003), BASFI (r = -0.399, p = 0.005 and r = 0.513, p=0.001) and BASMI (r = -0.382, p = 0.008 and r = 0.482, p= 0.001) respectively. Conclusion: QoL was impaired in AS patients with highest impact on physical health especially in association with peripheral arthritis. SF-36 and ASQol have a comparable achievement in the evaluation of QoL in AS patients and both physical function and spinal mobility were identified as predictors of poor QoL.

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Evaluation of the Use of Sterilized and Non-Sterilized Peruibe Black Mud in Patients with Knee Osteoarthritis

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph18041666 ◽

2021 ◽

Vol 18 (4) ◽

pp. 1666 ◽

Cited By ~ 1

Author(s):

Paulo Fávio Macedo Gouvêa ◽

Zélia Maria Nogueira Britschka ◽

Cristina de Oliveira Massoco Salles Gomes ◽

Nicolle Gilda Teixeira de Queiroz ◽

Pablo Antonio Vásquez Salvador ◽

...

Keyword(s):

Quality Of Life ◽

Knee Osteoarthritis ◽

Short Form ◽

Serum Levels ◽

Double Blind ◽

Sf 36 ◽

Radiographic Grade ◽

Physical Functions ◽

Kellgren And Lawrence

This study aimed to evaluate the effects of treatment with Peruíbe Black Mud (PBM) on the clinical parameters and quality of life of patients with knee osteoarthritis and to compare the effects of PBM samples simply matured in seawater and PBM sterilized by gamma radiation. A controlled, double-blind trial was conducted with 41 patients divided into two treatment groups composed of 20 and 21 patients: one group was treated with matured PBM and the other with sterilized PBM. Evaluations were done using the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) and the Medical Outcomes Study Short Form 36 (SF-36) questionnaires, the Kellgren and Lawrence (KL) radiographic scale, and the quantification of the serum levels of inflammatory biomarkers. An improvement in pain, physical functions, and quality of life was observed in all of the patients who underwent treatment with both simply matured and sterilized PBM. Nine patients showed remission in the KL radiographic scale, but no statistically significant differences were observed in the serum levels of inflammatory mediators before or after treatment. Peruíbe Black Mud proves to be a useful tool as an adjuvant treatment for knee osteoarthritis (OA), as shown by the results of the WOMAC and SF-36 questionnaires and by the remission of the radiographic grade of some patients on the Kellgren and Lawrence scale.

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Comorbidity of Fibromyalgia in Primary Knee Osteoarthritis: Potential Impact on Functional Status and Quality of Life [Corrigendum]

Open Access Rheumatology Research and Reviews ◽

10.2147/oarrr.s267971 ◽

2020 ◽

Vol Volume 12 ◽

pp. 125-126

Author(s):

Marwa Yahia Mahgoub ◽

Basant Mohamed Elnady ◽

Haytham Sayed Abdelkader ◽

Raghdaa Abdelkhaleq Abdelhalem ◽

Waleed Ahmed Hassan

Keyword(s):

Quality Of Life ◽

Knee Osteoarthritis ◽

Functional Status ◽

Potential Impact

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COMPARING QUALITY OF LIFE AMONG PEOPLE WITH DIFFERENT PATTERNS AND SEVERITIES OF KNEE OSTEOARTHRITIS

Journal of Musculoskeletal Research ◽

10.1142/s0218957706001650 ◽

2006 ◽

Vol 10 (01) ◽

pp. 47-55 ◽

Cited By ~ 2

Author(s):

Boonsin Tangtrakulwanich ◽

Virasakdi Chongsuvivatwong ◽

Alan F. Geater

Keyword(s):

Quality Of Life ◽

Knee Osteoarthritis ◽

Short Form ◽

Population Based ◽

Sf 36 ◽

Southern Thailand ◽

Skyline View ◽

Short Form Health ◽

Severe Grade

Objective: To identify what extent different patterns and severities of involvement affect quality of life of people suffering knee osteoarthritis. Methods: This population-based survey involved 288 women and 288 men aged 40 years or older from Songkhla province, southern Thailand. Quality of life was measured using the Medical Outcome Study Short Form Health sutvery (SF-36) and Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC). Radiographic investigation included antero-posterior and skyline view of both knees. Osteoarthritis was categorized into 3 patterns; isolated patellofemoral, isolated tibiofemoral and combined with diagnosis based on Kellgren & Lawrence grade 2 or higher. Results: Quality of life as measured by SF-36 and WOMAC showed poorer score in moderate or severe grade than in mild grade of severity. Isolated patellofemoral and combined patterns demonstrated showed poorer scores on both WOMAC and SF-36 than isolated tibiofemoral pattern. Body mass index, income level and pattern of involvement could independently predict total scores of WOMAC, while age, marital status and pattern of involvement affected total score of SF-36. Conclusion: Pattern of involvement is a better predictor of quality of life than disease severity in patients with knee osteoarthritis.

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