scholarly journals Recurrent Pregnancy Induced Pemphigus Vulgaris: A Rare Case Report

2020 ◽  
Vol 12 (3) ◽  
pp. 92-96
Author(s):  
Irsalina Husna Azwir ◽  
Khairuddin Djawad ◽  
Nurelly N. Waspodo ◽  
Asnawi Madjid
Keyword(s):  
Case Report ◽  
Fetal Death ◽  
Pemphigus Vulgaris ◽  
Intrauterine Fetal Death ◽  
First Line ◽  
Systemic Corticosteroids ◽  
Rare Case Report ◽  
Life Threatening ◽  
History Of ◽  
Great Resolution

Abstract Pemphigus vulgaris is a potentially life-threatening bullous autoimmune disease that can be triggered by various factors, one of which is pregnancy. Cases of pregnancy induced pemphigus are rare, and can result in devastating outcomes, both from the maternal or fetal perspectives if not treated promptly and adequately. The use of systemic corticosteroids is paramount to improve the outcome of the patient and fetus and it is a first-line treatment for the disease. Patients with a history of pemphigus should plan their pregnancies carefully, taking into consideration a minimum of 6 months remission before conception. This case report is about a 28-year-old woman with a history of pemphigus vulgaris that did not seek medical treatment of her pemphigus, which resulted in the intrauterine fetal death. The patient was treated with systemic corticosteroids and achieved great resolution to her blisters and overall wellbeing.

scholarly journals Pemphigus Vulgaris- A Case Report

2021 ◽  
pp. 324-328
Author(s):  
Mayur B. Wanjari ◽  
Deeplata Mendhe ◽  
Pratibha Wankhede ◽  
Sagar Alwadkar
Keyword(s):  
Case Report ◽  
Pemphigus Vulgaris ◽  
Entire Body ◽  
Case Presentation ◽  
Transmembrane Glycoprotein ◽  
Mouth Ulcer ◽  
Life Threatening ◽  
History Of ◽  
Epithelial Lesions ◽  
Intraepithelial Lesions

Introduction: Pemphigus is a rare and life-threatening autoimmune disease characterized by blisters and erosion of the skin and mucous membranes throughout the entire body. It mostly affects the mouth, eye, nose, throat as well as genitals. Pemphigus vulgaris is most common type of pemphigus. The epithelial lesions are caused by autoantibodies reacting with desmosomal glycoproteins found on the keratinocyte's cell surface. The binding of immunoglobulin G autoantibodies to desmoglein 3, a transmembrane glycoprotein adhesion molecule found on desmosomes, is the underlying process that causes intraepithelial lesions. Case Presentation: A 40-year-old male patient came to the hospital with a complaint of a mouth ulcer and a genital lesion that had been since 15 years. He is having a history of oral ulcer in oral mucosa and involvement of genital area in glans penis with a history of pain, bleeding, difficulty in swallowing.   Intervention: The patient was admitted to the hospital on 29/07/2021 and taken Inj. Rituximab 1gm in 500Ml Normal Saline in infusion pumps in over 6 Hours. Conclusion: In this case report, we mainly focus on expert dermatological management and excellent nursing care in managing the rare complicated case nicely. Early diagnosis and treatment of pemphigus Vulgaris help determine the course of the disease of the patient and is done by a dermatologist.

scholarly journals Pemphigusvulgaris in pregnancy. A rare case report

2019 ◽  
Vol 18 (3) ◽  
pp. 101-104
Author(s):  
Ioannis Kokolakis ◽  
Fanis Makrigiannakis ◽  
Sabine Kruger ◽  
Konstantinos Krasagakis ◽  
Antonios Makrigiannakis
Keyword(s):  
Hormone Level ◽  
Adverse Outcome ◽  
Preterm Births ◽  
Pemphigus Vulgaris ◽  
Preterm Baby ◽  
Systemic Corticosteroids ◽  
Rare Case Report ◽  
Appropriate For Gestational Age ◽  
Life Threatening ◽  
Effect Of Treatment

Pemphigus vulgaris (PV) is an autoimmune, bullous, mucocutaneous and potentially life-threatening disease. During pregnancy the occurrence of PV is exceedingly rare and its condition will become more complicated due to different mother’s hormone level and the effect of treatment on both mother and her fetus. PV may be associated with an adverse outcome, such as fetal growth restriction and preterm births. We report a case of a 33-year-old woman who was firstly diagnosed with PV during pregnancy. Treatment of highdoses systemic corticosteroids was instituted to control the disease. She delivered a healthy live preterm baby, appropriate for gestational age with no skin or mucosal lesions or other apparent complications.

scholarly journals A RARE CASE REPORT ON MYXOEDEMA COMA

2021 ◽  
pp. 1-3
Author(s):  
SHANTHI B ◽  
MARY CHANDRIKA A
Keyword(s):  
Case Report ◽  
Female Patient ◽  
Rare Case ◽  
Previous History ◽  
Altered Mental Status ◽  
Electrolyte Imbalance ◽  
Rare Case Report ◽  
Life Threatening ◽  
History Of ◽  
Life Threatening Complication

Myxoedema coma is a sporadic life-threatening complication of severe hypothyroidism with high mortality. Altered mental status and hypothermia are the main symptoms of myxoedema coma. Apart from that, hypoxia, bradycardia, hypotension, anemia, and hyponatremia would be present. Few patients present comatose with severe myxoedema. Presenting coma may mislead the diagnosis of this condition. A female patient presented with fever, breathlessness, and disorientation was admitted. First diagnosed to have electrolyte imbalance and treatment was started accordingly. The patient did not show much of an improvement, and it took a day to identify the presence of severe hypothyroidism. Treating hypothyroidism resulted in an advance in the patient condition. Patients’ previous history of hypothyroidism was not informed during admission. It is always tough to diagnose myxoedema coma when the patients’ previous history of hypothyroidism is unknown. Hence, it is still essential to have hypothyroidism in mind while treating patients with comatose. This case has been reported to alert physicians in diagnosing myxoedema coma patients and to proceed with the treatment at the earliest.

scholarly journals Asymptomatic mediastinal extra-adrenal paraganglioma as a cause of sudden death: a case Report

2019 ◽  
Vol 14 (1) ◽  
pp. 564-567
Author(s):  
Qiancheng Xu ◽  
Yingya Cao ◽  
Hongzhen Yin ◽  
Rongrong Wu ◽  
Tao Yu ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Case Report ◽  
Respiratory Failure ◽  
Pressure Drop ◽  
Thoracic Cavity ◽  
Severe Hypotension ◽  
Life Threatening ◽  
History Of ◽  
Posterior Mediastinal ◽  
Extra Adrenal Paraganglioma

AbstractA 23-year-old female patient was referred for treatment of a posterior mediastinal tumour. There was no history of hypertension or headache and no other complaints. The patient’s blood pressure increased to 210/125 mmHg after surgically manipulating the tumour, subsequently reversing to severe hypotension (25/15 mmHg) immediately after the tumour was removed. The life-threatening and irreversible blood pressure drop was difficult to treat with fluid and vasopressors, and the patient ultimately died of cardio-respiratory failure. Asymptomatic paraganglioma can be non-functional but can also be fatal. For any lump in the thoracic cavity, paraganglioma should be ruled out.

scholarly journals Polymeric Nanocarriers: A Transformation in Doxorubicin Therapies

Materials ◽  
2021 ◽  
Vol 14 (9) ◽  
pp. 2135
Author(s):  
Kamila Butowska ◽  
Anna Woziwodzka ◽  
Agnieszka Borowik ◽  
Jacek Piosik
Keyword(s):  
Drug Delivery ◽  
Wide Spectrum ◽  
Stimuli Responsive ◽  
First Line ◽  
Medical Expenses ◽  
Polymeric Nanocarriers ◽  
Essential Properties ◽  
Life Threatening ◽  
History Of ◽  
Cancerous Cells

Doxorubicin, a member of the anthracycline family, is a common anticancer agent often used as a first line treatment for the wide spectrum of cancers. Doxorubicin-based chemotherapy, although effective, is associated with serious side effects, such as irreversible cardiotoxicity or nephrotoxicity. Those often life-threatening adverse risks, responsible for the elongation of the patients’ recuperation period and increasing medical expenses, have prompted the need for creating novel and safer drug delivery systems. Among many proposed concepts, polymeric nanocarriers are shown to be a promising approach, allowing for controlled and selective drug delivery, simultaneously enhancing its activity towards cancerous cells and reducing toxic effects on healthy tissues. This article is a chronological examination of the history of the work progress on polymeric nanostructures, designed as efficient doxorubicin nanocarriers, with the emphasis on the main achievements of 2010–2020. Numerous publications have been reviewed to provide an essential summation of the nanopolymer types and their essential properties, mechanisms towards efficient drug delivery, as well as active targeting stimuli-responsive strategies that are currently utilized in the doxorubicin transportation field.

scholarly journals Intrauterine fetal death in triplet gestation caused by feto-fetal transfusion syndrome – a case report

2016 ◽  
Vol 2 (4) ◽  
pp. 213-217
Author(s):  
Lingling Long ◽  
Jie Yan ◽  
Qiyan Li ◽  
Ziqi Zhou ◽  
Haixiao Deng ◽  
...  
Keyword(s):  
Case Report ◽  
Fetal Death ◽  
Intrauterine Fetal Death

Arterial Thrombosis and Gangrene Secondary to Arachnidism

Vascular ◽  
2009 ◽  
Vol 17 (4) ◽  
pp. 239-242
Author(s):  
Jan M. Eckermann ◽  
Theodore H. Teruya ◽  
Christian Bianchi ◽  
Ahmed M. Abou-Zamzam
Keyword(s):  
Case Report ◽  
Lower Extremity ◽  
Vascular Disease ◽  
Tissue Damage ◽  
Arterial Thrombosis ◽  
Progressive Necrosis ◽  
Life Threatening ◽  
History Of ◽  
Spider Bites ◽  
Spider Bite

Spider bites can cause local tissue damage as well as life-threatening complications. This is a case report of a female with no history of lower extremity vascular disease who presented with a spider bite on the dorsum of her foot. She developed progressive necrosis and eventually suffered limb loss despite attempts at revascularization.

scholarly journals Non-painful severe variant form of eruptive lingual papillitis: A case report and literature review

2021 ◽  
Vol 13 (2) ◽  
Author(s):  
Manal Ahmed Halwani
Keyword(s):  
Emergency Department ◽  
Case Report ◽  
Literature Review ◽  
Oral Hygiene ◽  
Rare Case ◽  
Dorsal Surface ◽  
Variant Form ◽  
Girl Child ◽  
Rare Case Report ◽  
History Of

Eruptive lingual papillitis is a common benign disorder manifested by inflammation of fungiform papillae on the dorsolateral surface of the tongue. Several variants of lingual papillitis have been reported since 1997, most or all of them with painful erythematous papules. Here we report a case of 6 years old girl child with non-painful severe variant form of eruptive lingual papillitis presented to the emergency department. The entire dorsal surface of the tongue was surfaced by 2-3mm by multiple erythematous papules and some with a white or yellowish colour. The papules were excessively inflamed, pigmented, aggregated, and crusted. The cause was idiopathic which resolved within ten days. The parent and patient were reassured with advice to practice oral hygiene. This is a rare case report describing non-painful lingual papillitis without a history of any prior episodes.

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