scholarly journals STIGMASTANE-STEROID FROM THE BARK OF Chisocheton lasiocarfus (Meliaceae)

Jurnal Kimia ◽  
2017 ◽  
pp. 168
Author(s):  
Nurlelasari Nurlelasari ◽  
Fajar Fauzi Abdullah ◽  
Nadya Thufaila ◽  
Rani Maharani ◽  
Desi Harnet ◽  
...  
Keyword(s):  
Spectral Data ◽  
Spectroscopic Data ◽  
Chemical Structure ◽  
First Time

Stigmastan-steroid, stigma-4-ene-3-on (1) has been isolated from the bark of Chisocheton lansiocarpus. The chemical structure of stigmastan-steroid was identified based on spectroscopic data and by comparison of spectral data obtained previously. The discovery of stigma-4-ene-3-on in C. lansiocarpus was shown in this study for the first time.

scholarly journals SENYAWA STIGMASTEROL (STEROID) DARI KULIT BATANG Chisocheton celebicus koord (MELIACEAE)

2021 ◽  
Vol 14 (1) ◽  
Author(s):  
Dewa Gede Katja
Keyword(s):  
Spectral Data ◽  
Spectroscopic Data ◽  
Chemical Structure ◽  
2D Nmr ◽  
Isolated Compound ◽  
First Time

ABSRTAKStigmasterol (suatu steroid) dengan rumus molekul C29H48O  telah doiisolasi dari kulit batang chisocheton celebicus (Meliacea) menggunakan pelarut n-heksan, kemudian dipisahkan dengan teknik kromatografi dan dihasilkan isolat murni berupa kristal jarum tak berwarna(10,2 mg) dengan titik leleh 169-1710C. Struktur kimia stigmasterol diidentifikasi berdasarkan data-data spektroskopi meliputi IR, NMR-1D, NMR-2D dan masa,serta perbandingan dengan data spektroskopi yang diperoleh dari literatur. Penemuan senyawa stigmasterol dari kulit batang Chisocheton celebicus dilaporkan untuk pertama kalinya dalam penelitian ini.. ABSTRACTStigmasterol C29H48O has been isolated from the bark of Chisocheton celebicus (Meliacee) in n-hexan and separated using several chromatography and it has been pure isolated the crystal calorness compound (10,2 mg). The chemical structure of isolated compound was identified on the basis of spectroscopic data including IR, 1D-NMR, 2D-NMR and mass along with comparison with those spectral data previously reported. The discovery of stigmasterol compound from the bark C. celebicus reported for the first time in this study.

scholarly journals STEROIDS FROM THE SUPER RED DRAGON FRUIT (Hylocereus costaricensis)

Jurnal Kimia ◽  
2019 ◽  
pp. 229
Author(s):  
H. Supriadi ◽  
S. Salam ◽  
F. F. Abdullah ◽  
A. Subarnas ◽  
R. Sidik ◽  
...  
Keyword(s):  
Ethyl Acetate ◽  
Spectral Data ◽  
Spectroscopic Data ◽  
Chemical Structure ◽  
Ethyl Acetate Extract ◽  
Dragon Fruit ◽  
First Time

Two steroids compounds, 7?-Hydoxy ?-sitosterol (1) and ?-sitosterol (2), have been isolated from ethyl acetate extract of the fresh Super Red Dragon Fruit (Hylocereus costaricensis).The chemical structure of compounds 1 and 2 were identified by spectroscopic data including UV, IR, NMR-1D, NMR-2D  and mass as well as by comparing  with previously reported spectral data. Compounds 1 and 2 were reported for the first time from dragon fruit (Hylocereus costaricensis). Keywords: 7?-Hydoxy ?-sitosterol, ?-sitosterol, Hylocereus costaricensis, steroids.

scholarly journals DAMMARANE-TYPE TRITERPENOIDS FROM THE STEMBARK OF CHISOCHETON PENTANDRUS (MELIACEAE)

Jurnal Kimia ◽  
2020 ◽  
pp. 89
Author(s):  
D. G. Katja ◽  
S. Salam ◽  
. Nurlelasari ◽  
D. Harneti ◽  
R. Maharani ◽  
...  
Keyword(s):  
Spectral Data ◽  
Spectroscopic Data ◽  
Hexane Extract ◽  
First Time

Two dammarane-type triterpenoids, cabraleadiol (1) and cabraleahydroxylactone (2), have been isolated from n-hexane extract of the stembark of  Chisocheton pentandrus (Meliaceae). The structure of compounds 1 and 2 were determined by spectroscopic data mainly NMR and mass as well as by comparing with previously reported spectral data. Compounds 1 and 2 were reported for the first time from Chisocheton pentandrus.   Keywords:   Cabraleadiol, Cabraleahydroxylactone, Chisocheton pentandrus, Meliaceae.

scholarly journals Melicope moluccana Antimalarial Activity of Furoquinoline Alkaloids from the Leaves of Melicope moluccana

2020 ◽  
Vol 5 (2) ◽  
pp. 138-142
Author(s):  
Ryan Ayub Wahjoedi ◽  
Ratih Dewi Saputri ◽  
Tjitjik Srie Tjahjandarie ◽  
Mulyadi Tandjung
Keyword(s):  
Plasmodium Falciparum ◽  
Spectral Data ◽  
Spectroscopic Data ◽  
Chemical Structure ◽  
Antimalarial Activity ◽  
2D Nmr ◽  
Esi Ms ◽  
Ic50 Values

Two furoquinoline alkaloids, leptanoine C (1) and haplopine-3,3´-dimethylallyl ether (2) were isolated from the leaves of Melicope moluccana. The chemical structure of both compounds was determined based on spectroscopic data, including UV, IR, HR-ESI-MS, 1D, and 2D NMR spectral data. The antimalarial activity of compounds 1-2 against Plasmodium falciparum 3D7 showing their IC50 values are 0.18 ppm and 2.28 µg/mL, respectively.

scholarly journals Dammarane-Type Triterpenoids from The Stembark of Aglaia argentea (Meliaceae)

2018 ◽  
Vol 4 (1) ◽  
pp. 7-13
Author(s):  
Ace Tatang Hidayat ◽  
Kindi Farabi ◽  
Ida Nur Farida ◽  
Kansy Haikal ◽  
Nurlelasari Nurlelasari ◽  
...  
Keyword(s):  
Cytotoxic Activity ◽  
Spectral Data ◽  
Chemical Structure ◽  
2D Nmr ◽  
Leukemia Cells ◽  
Ic50 Values ◽  
First Time ◽  
Murine Leukemia

Two dammarane-type triterpenoids, 20S,24S-epoxy-3α,25-dihydroxydammarane (1) and 3α-acetyl-20S,24S-epoxy-3α,25-dihydroxydammarane (2), have been isolated from the stembark of Aglaia argentea. The chemical structure of compounds (1 and 2) were identified by spectroscopic evidences including UV, IR, 1D-NMR, 2D-NMR and MS as well as by comparing with previously reported spectral data. Those compounds were isolated from this plant for first time. Compounds (1 and 2) showed cytotoxic activity against P-388 murine leukemia cells with IC50 values of 23.96 and 8.14 mM, respectively.DOI:http://dx.doi.org/10.15408/jkv.v4i1.7065

scholarly journals FLAVONOLS FROM THE LEAVES Lygodium microphyllum (Lygodiaceae)

Jurnal Kimia ◽  
2017 ◽  
Author(s):  
Hadi Kuncoro ◽  
Kindi Farabi ◽  
Euis Julaeha ◽  
Laode Rijai ◽  
Yoshihito Shiono ◽  
...  
Keyword(s):  
Ethyl Acetate ◽  
Spectral Data ◽  
Spectroscopic Data ◽  
Ethyl Acetate Extract ◽  
Chemical Structures ◽  
First Time

Flavonol compounds, quercetin (1) and quercetin-3-O-?-D-glucopyranoside (2) have been isolated from the ethyl acetate extract of Lygodium microphyllum leaves. The chemical structures of flavonol compounds were identified based on spectroscopic data and by comparison of spectral data obtained previously. The discovery of flavonol compounds in Lygodium microphyllum was shown in this study for the first time.

scholarly journals Flavanoids fromthe Stembark of Chisocheton pentandrus(Meliaceae)

2017 ◽  
pp. 122-126
Author(s):  
Supriatno Supriatno ◽  
Ace Tatang Hidayat ◽  
Kindi Farabi ◽  
Fajar Fauzi Abdullah ◽  
Nurlelasari Nurlelasari ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cytotoxic Activity ◽  
Cancer Cells ◽  
Spectral Data ◽  
Breast Cancer Cells ◽  
Chemical Structure ◽  
First Time ◽  
Mcf 7

Two flavanoid compounds, catechin (1) and epicatechin (2), have been isolated from the stembark of Chisocheton pentandrus. The chemical structure of compounds1and2were identified byspectroscopic data including, UV, IR, NMR (1H, 13C, DEPT 135°, HMQC, HMBC, 1H-1H COSY) and MS and by comparing with previously reported spectral data. Compounds 1 and 2, were isolated in this plant for first time and showed no cytotoxic activity against MCF-7 breast cancer cells.

scholarly journals Chemical Constituents of the Marine Sponge Aaptos aaptos (Schmidt, 1864) and Their Cytotoxic Activity

2021 ◽  
Vol 16 (2) ◽  
pp. 1934578X2199334
Author(s):  
Do Thi Trang ◽  
Bui Huu Tai ◽  
Dan Thuy Hang ◽  
Pham Hai Yen ◽  
Phan Thi Thanh Huong ◽  
...  
Keyword(s):  
Cytotoxic Activity ◽  
Spectral Data ◽  
Absolute Configuration ◽  
Marine Sponge ◽  
Chemical Constituents ◽  
2D Nmr ◽  
Extensive Analysis ◽  
First Time ◽  
Tddft Method ◽  
Mcf 7

Seven compounds (1-7) were isolated from the marine sponge Aaptos aaptos living in the Vietnamese sea. Their structures were determined as 2 hours, 5 H,7 H,9 H-9 S-hydroxy-imidazo[1,5- α]pyridine-1,3-dione (1), 3-([9-methylhexadecyl]oxy)propane-1,2-diol 2, 2,3-dihydro-2,3-dioxoaaptamine (3), indol-3-aldehyde (4), methyl indole-3-carboxylate (5) 4-hydroxy-5-(indole-3-yl)−5-oxo-pentan-2-one (6), and thymidine (7) by extensive analysis of HR-ESI-MS, 1D, and 2D NMR spectral data, as well as by comparison of the spectral data with those reported in the literature. In addition, the absolute configuration of 1 was determined from the experimental ECD spectrum and comparison of this with the theoretical ECD calculations using the TDDFT method. Compounds 1 and 2 were isolated from nature for the first time. Compound 3 induced cytotoxic activity against SK-LU-1, MCF-7, HepG2, and SK-Mel-2 cell lines with IC50 values of 41.27 ± 2.63, 40.70 ± 2.65, 34.31 ± 3.43, and 36.63 ± 1.40 µM, respectively.

Isolation and Structure Determination of a Heat Shock Protein Inducer, Asparagus-Derived Proline-Containing 3-Alkyldiketopiperazines (Asparaprolines), From a Standardized Extract of Asparagus officinalis Stem

2020 ◽  
Vol 15 (3) ◽  
pp. 1934578X2091468
Author(s):  
Shoichiro Inoue ◽  
Jun Takanari ◽  
Keima Abe ◽  
Ayako Nagayama ◽  
Yukinobu Ikeya ◽  
...  
Keyword(s):  
Heat Shock ◽  
Heat Shock Protein ◽  
Spectroscopic Data ◽  
Asparagus Officinalis ◽  
Hsp70 Mrna ◽  
Mrna Induction ◽  
Natural Amino Acids ◽  
First Time ◽  
Hsp70 Induction

ETAS® has been developed from the stems of Asparagus officinalis L. as a functional ingredient for nutraceuticals. ETAS possesses heat shock protein 70 (HSP70) induction activity and may contribute to maintenance and improvement of health. Here, 3 compounds (1, 2, 3) were isolated from ETAS. The structures of 1, 2, and 3 were deduced by HREIMS and NMR spectroscopic data, and the compounds were identified as cyclo(l-Phe-l-Pro), cyclo(l-Tyr-l-Pro), and cyclo(l-Leu-l-Pro), respectively. Each compound contained a diketopiperazine ring derived from proline with an alkyl group at C-3; thus, we termed them asparagus-derived proline-containing 3-alkyldiketopiperazines (Asparaprolines). In an HSP70 mRNA induction assay in HL-60 cells, Asparaprolines significantly enhanced the expression of HSP70 mRNA compared with a control. To our knowledge, these results demonstrate for the first time that proline-containing diketopiperazines derived from natural amino acids exhibit HSP70 mRNA induction activity.

Chemical components of the rhizomes of Drynaria fortunei (KUNZE) J. Sm. (polypodiaceae) in Vietnam

2011 ◽  
Vol 76 (9) ◽  
pp. 1133-1139 ◽  
Author(s):  
Pham Thi Nhat Trinh ◽  
Nguyen Cong Hao ◽  
Phan Thanh Thao ◽  
Le Tien Dung
Keyword(s):  
Data Analysis ◽  
Spectral Data ◽  
Phenolic Acid ◽  
Ethanol Extract ◽  
Chemical Components ◽  
Spectroscopic Methods ◽  
Phenylpropanoid Glycoside ◽  
Spectral Data Analysis ◽  
First Time

From the ethanol extract of Drynaria fortunei (KUNZE) J. Sm., a new phenylpropanoid glycoside, fortunamide (1), was isolated and characterized by spectroscopic methods. Together with a new glycoside, 9 known compounds, including three curcuminoids (2–4), two isoprenylated flavonoids (5, 6), two flavonoids (7, 8), one monoterpenoid (9) and one phenolic acid (10) were isolated and identified by spectral data analysis from the rhizomes of Drynaria fortunei (KUNZE) J. Sm. Eight of them were isolated from Drynaria fortunei (KUNZE) J. Sm. for the first time.

Sign in / Sign up

Export Citation Format

Share Document