scholarly journals Total cement knee arthroplasty in patients of 85–95 years old with terminal stage of degenerative knee disease

2018 ◽  
Vol 177 (6) ◽  
pp. 49-53 ◽  
Author(s):  
V. Yu. Murylev ◽  
P. M. Elizarov ◽  
A. V. Muzychenkov ◽  
Ya. A. Rukin ◽  
A. A. Dering ◽  
...  
Keyword(s):  
Total Knee Arthroplasty ◽  
Knee Arthroplasty ◽  
Charlson Comorbidity Index ◽  
Surgical Intervention ◽  
Age Group ◽  
Old Patients ◽  
Terminal Stage ◽  
Knee Arthrosis ◽  
Comorbidity Index ◽  
Total Knee

The objectiveof the study is to make the analysis of the results of total cement knee arthroplasty in the most difficult age group of 85–95 years old patients.Material and methods.40 patients with terminal knee arthrosis were selected based on their comorbidity.Results.Patients with the Charlson comorbidity index of 5–8 points need hospitalization for the treatment of aggravating somatic pathology, as preparation for a future knee arthroplasty. In the operated patients, the result on the KOOS was (76±7.19), and on the WOMAC was (151±4.83) a year after the arthroplasty.Сonclusion.Surgical intervention – total knee arthroplasty in patients of 85–95 years old is possible only if its risk is minimized.

scholarly journals The Impact of Pre-emptive Large Dose of Methylprednisolone Combined With Gabapentin on Pain Treatment and Convalescence After Total Knee Arthroplasty in Elderly. A Randomized Control Study

2021 ◽  
Author(s):  
Henryk Liszka ◽  
Małgorzata Zając ◽  
Artur Gądek
Keyword(s):  
Total Knee Arthroplasty ◽  
Single Dose ◽  
Knee Arthroplasty ◽  
Opioid Analgesic ◽  
Control Group ◽  
Study Group ◽  
Intensity Level ◽  
Old Patients ◽  
Total Knee ◽  
The Impact

Abstract Background The aim of the study was to assess whether administration of gabapentin and methylprednisolone as “pre-emptive analgesia” in a group of patients above 65 years of age would be effective in complex pain management therapy following total knee arthroplasty (TKA). Material and Methods One hundred seventy, above 65 years old patients were qualified for the study, and 10 patients were excluded due to clinical situation. One hundred sixty patients were double-blind randomized into two groups: the study (eighty patients) and controls (eighty patients). The study group received as “pre-emptive” analgesia a single dose of 300 mg oral gabapentin and 125 mg intravenous methylprednisolone, while the others placebo. Perioperatively, all the patients received opioid and nonopioid analgesic agents calculated for 1 kg of body weight. We measured the levels of inflammatory markers (leukocytosis, C-reactive protein - CRP), pain intensity level at rest (numerical rating scale - NRS), the life parameters and all complications. Results Following administration of gabapentin and methylprednisolone as “pre-emptive” analgesia CRP values being lower on all postoperative days ( 1, 2 days - p<0,00001, 3 day – p=000538), leukocytosis on day 2 (p<0,0086) and 3 (p<0,00042), the NRS score at rest 6, 12 (p<0,000001), 18 (p<0,00004) and 24 (p=0,005569) hours postoperatively . Methylprednisolone with gabapentin significantly decreased the dose of parenteral opioid preparations (p=0,000006). The duration time of analgesia was significantly longer in study group (p<0,000001). No infectious complications were observed; in the control group, one patient manifested transient ischaemic attack (TIA). Conclusion The use of gabapentin and methylprednisolone at a single dose decreases the level of postoperative pain on the day of surgery, the dose of opioid analgesic preparations, the level of inflammatory parameters without infectious processes.

scholarly journals Total Knee Arthroplasty Outcomes Depending on the Degree 11 of Angular Deformity

2016 ◽  
pp. 11-15
Author(s):  
A. A. Zykin ◽  
E. E. Malyshev ◽  
D. V. Pavlov ◽  
S. B. Korolyov
Keyword(s):  
Total Knee Arthroplasty ◽  
Knee Arthroplasty ◽  
Surgical Intervention ◽  
Soft Tissue Release ◽  
Angular Deformity ◽  
Treatment Results ◽  
Leg Axis ◽  
Sf 36 ◽  
Hospitalization Period ◽  
Total Knee

The analysis of total knee arthroplasty results was performed in 106 patients operated on for III stage of deforming gonarthrosis. All patients were divided into 2 groups depending on the presence of the angular extremity axis deformity. Clinical and functional assessment was performed using visual analog scale, Joseph & Kaufman scale, SF-36 questionnaire. Treatment results were evaluated in 3, 6 months and 1, 3, 5 years after intervention. In the group of patients with axial leg deformity the duration of surgical intervention, intraoperative blood loss and postoperative hospitalization period were higher than in patients with normal leg axis but the differences were not significant. The height of the implant insert was 12 (8-14) mm with normal axis and 14 (14-15) mm with axial deformity ( p =0.000187). Correction of the leg axis during arthroplasty required larger bone cuts and soft tissue release but the parameters characterizing leg axis normalization did not differ statistically significant between the groups. However in 5 years after intervention the patients with normal lower extremity axis showed reliably better results by all scales and questionnaires.

scholarly journals Two-Stage Revision Total Knee Arthroplasty in Cases of Periprosthetic Joint Infection: An Analysis of 50 Cases

2015 ◽  
Vol 9 (1) ◽  
pp. 49-56 ◽  
Author(s):  
Leif Claassen ◽  
Christian Plaass ◽  
Kiriakos Daniilidis ◽  
Tilman Calliess ◽  
Gabriela von Lewinski
Keyword(s):  
Total Knee Arthroplasty ◽  
Success Rate ◽  
Knee Arthroplasty ◽  
Periprosthetic Joint Infection ◽  
Persistent Infection ◽  
Joint Infection ◽  
Revision Total Knee Arthroplasty ◽  
Two Stage ◽  
Comorbidity Index ◽  
Total Knee

Objectives: A periprosthetic joint infection (PJI) is a significant complication after total knee arthroplasty (TKA). Still there is no agreement on a perfect diagnosis and treatment algorithm. The aim of this study was to evaluate the success and revision rates after two-stage revision total knee arthroplasty (TKA) and factors that affect the success rate.Material and Methods:50 consecutive two-stage revision TKAs were performed between January 2011 and December 2012. We retrospectively reviewed study patient's charts including demographics, prior surgeries, comorbidities, incidence of persistent infection and revisions. At the final follow-up examination the patient's satisfaction, pain level and disorders were evaluated. A successful clinical outcome was defined as a functioning prosthesis without wound healing disorders, no sinuses tracts or other clinical evidence of a persistent infection.Results: Re-implantation of prosthesis was performed in 47 cases; three patients received a septic arthrodesis. Twelve patients had a persistent infection despite two-stage re-implantation resulting in a success rate of 76.0%. In eight of these twelve patients an infecting germ was isolated during second-stage procedure. Three patients received another two-stage revision arthroplasty and one patient an above knee amputation. A revision was performed in 23 of 50 patients (46.0%). Factors that diminish the success rate were further operations after primary TKA (p = 0.048), prior revision arthroplasties after TKA (p = 0.045), nicotine abuse (p = 0.048), Charlson comorbidity index above a score of 2 (p = 0.031) and a mixed flora during first-stage procedure (p < 0.001). Age, sex, immune status, chronic anticoagulant use, rheumatoid arthritis, body mass index and the presence of multidrug resistant germs showed no significant effect on success rate (p > 0.05).Conclusion: We found that patients who required surgery after the primary TKA, had a higher Charlson comorbidity index or were found to have mixed flora during explantation. The treatment of PJI remains difficult, both for the patient and for the treating surgeons.

Surgical and Medical Costs for Fibromyalgia Patients Undergoing Total Knee Arthroplasty

2019 ◽  
Vol 32 (11) ◽  
pp. 1069-1074
Author(s):  
Tara Moore ◽  
Nipun Sodhi ◽  
Wayne B. Cohen-Levy ◽  
Joseph Ehiorobo ◽  
Angad Kalsi ◽  
...  
Keyword(s):  
Total Knee Arthroplasty ◽  
Knee Arthroplasty ◽  
Surgical Complication ◽  
Medical Complications ◽  
Readmission Rates ◽  
Surgical Costs ◽  
Episodes Of Care ◽  
Comorbidity Index ◽  
Total Knee ◽  
Financial Losses

AbstractThe potential added costs of managing fibromyalgia patients after total knee arthroplasty (TKA) have not been assessed. Therefore, the purpose of this study was to perform a cost analysis of fibromyalgia versus nonfibromyalgia patients who underwent TKA. Specifically, we evaluated the following episodes of care: (1) readmission rates, (2) total costs, (3) total reimbursements, and (4) net losses for surgical and medical complications. Patients who underwent TKAs between 2005 and 2014 from the Medicare Standard Analytical Files of the PearlDiver supercomputer were propensity score matched by patients with and without fibromyalgia in a 1:1 ratio based on age, sex, and the Charlson Comorbidity Index, yielding a total of 305,510 patients distributed equally between the cohorts for analysis. Odds ratios (ORs), 95% confidence intervals (CIs), and p-values were calculated. Mean costs, total costs, and total reimbursements were assessed as along with total net losses, which were defined as total costs minus total reimbursements. Fibromyalgia patients had similar 90-day readmission rates compared with nonfibromyalgia patients (OR: 1.03; 95% CI: 1.00–1.06; p = 0.06) but incurred lower readmission costs (US$2,318,384,295 vs. US$2,534,482,404; p < 0.001). Although fibromyalgia patients had higher total reimbursements for medical complications ($27,758,057 vs. US$18,780,610; p < 0.001), the increased management costs (US$106,049,870 vs. US$66,080,469; p < 0.001) led to greater net losses (US$78,291,813 vs. US$47,299,859; p < 0.001). Similarly, although fibromyalgia patients had higher total reimbursements for surgical complications (US$94,192,334 vs. US$73,969,026; p < 0.001), the increased surgical costs (US$382,122,613 vs. US$306,359,910; p < 0.001) led to greater net losses (US$287,930,279 vs. US$232,390,884; p < 0.001). This study highlights some of the potential financial discrepancies of managing patients with fibromyalgia. Our findings suggest medical and surgical complication costs to be greater than reimbursement, resulting in overall net financial losses. These findings need to be considered in the light of health care reform and cost structuring.

scholarly journals Optimal Age Group Selection and Development of a Nomogram To Predict Complications in Patients Undergoing Simultaneous Bilateral Total Knee Arthroplasty

2021 ◽  
Author(s):  
Kui-shuai XU ◽  
Liang ZHANG ◽  
Zhongkai REN ◽  
Tianrui WANG ◽  
Xia ZHAO ◽  
...  
Keyword(s):  
Total Knee Arthroplasty ◽  
Knee Arthroplasty ◽  
Calibration Curve ◽  
Multivariate Logistic Regression Analysis ◽  
Area Under The Curve ◽  
Operation Time ◽  
Age Group ◽  
Bilateral Total Knee Arthroplasty ◽  
Actual Observation ◽  
Total Knee

Abstract Purpose By comparing the occurrence of complications at 30 days after Simultaneous bilateral total knee arthroplasty (SBTKA) for each age group, the optimal age range of patients receiving SBTKA was determined.An individualized histogram model was established to predict complications within 30 days after SBTKA. Methods The general data of 861 patients who received SBTKA in our hospital on January 1, 2012 and March 31, 2017 were retrospectively analyzed. According to the age of the patients, they were divided into four ages: less than 60 years old, 60 to 64 years old, 65 to 69 years old and over 70 years old. The incidence of complications in different ages was studied.According to the occurrence of complications, 96 cases were included in the complication group and 765 cases in the non-complication group. Univariate and multivariate Logistic regression analysis was conducted to determine and screen out the independent risk factors for complications after SBTKA, and then R software was used to construct the prediction model of the nomogram.The area under the curve (AUC), calibration curve, and decision curve analysis (DCA) were selected to evaluate the nomogram. Results Patients aged 60 to 64 years had the lowest overall postoperative complication rate (7.17%).Five independent predictors were identified by multivariate analysis and were used to establish the nomogram.The AUC of the nomogram was 0.851(95%CI:0.819–0.883).The calibration curve showed that the prediction of nomogram was highly consistent with the actual observation, and DCA showed that nomogram had good clinical usefulness. Conclusion The optimal age group for SBTKA is between 60 and 64 years of age, where the incidence of complications is lowest.Older age, lower preoperative hemoglobin levels, higher preoperative blood urea nitrogen(BUN) levels, longer operation time, and ASA grade ≥ III were identified as independent predictors of complications within 30 days after SBTKA.A nomogram containing the above five predictors could accurately predict the risk of complications within 30 days after SBTKA.

scholarly journals Differences in total knee arthroplasty goals by age group in osteoarthritis patients referred to orthopaedic surgery

2015 ◽  
Vol 23 ◽  
pp. A342
Author(s):  
G.A. Hawker ◽  
B. Spady ◽  
A.-M. Adachi ◽  
S. Rahman ◽  
J. Squire Howden ◽  
...  
Keyword(s):  
Total Knee Arthroplasty ◽  
Knee Arthroplasty ◽  
Orthopaedic Surgery ◽  
Age Group ◽  
Total Knee

Identifying Patterns and Predictors of Prescription Opioid Use After Total Joint Arthroplasty

2021 ◽  
Author(s):  
Muhammad Ali Chaudhary ◽  
Michael K Dalton ◽  
Tracey P Koehlmoos ◽  
Andrew J Schoenfeld ◽  
Eric Goralnick
Keyword(s):  
Total Knee Arthroplasty ◽  
Total Hip Arthroplasty ◽  
Knee Arthroplasty ◽  
Surgical Intervention ◽  
Joint Arthroplasty ◽  
Prescription Opioid ◽  
Opioid Use ◽  
Factors Associated ◽  
Total Knee ◽  
Prescription Opioid Use

ABSTRACT Introduction Total hip arthroplasty and total knee arthroplasty account for over 1 million procedures annually. Opioids are the mainstay of postoperative pain management for these patients. In this context, the objective of this study was to determine patterns of use and factors associated with early discontinuation of opioids after total joint arthroplasty (TJA). Methods TRICARE claims data (2006-2014) were queried for adult (18-64 years) patients who underwent total hip arthroplasty or total knee arthroplasty. Prescription opioid use was identified from 6 months before and 6 months after surgical intervention. Prior opioid use was categorized as naïve, exposed (with non-sustained use), and sustained (6 month continuous use before surgery). Cox proportional-hazards models were used to identify factors associated with opioid discontinuation following TJA. Results Among the 29,767 patients included in the study, 15,271 (51.3%) had prior opioid exposure and 3,740 (12.5%) were sustained opioid users. At 6 months after the surgical intervention, 3,171 (10.6%) continued opioid use, 3.3% were among opioid naïve, 10.2% among exposed, and 33.3% among sustained users. In risk-adjusted models, prior opioid exposure (hazards ratio: 0.65, 95% CI: 0.62-0.67) and sustained prior use (hazards ratio: 0.33, 95% CI: 0.31-0.35) were the strongest predictors of lower likelihood of opioid discontinuation. Lower socio-economic status, depression, and anxiety were also strong predictors. Conclusion Prior opioid exposure was strongly associated with continued opioid dependence after TJA. Although one-third of prior sustained users continued use after surgery, approximately 10% of previously exposed patients became sustained users, making them the prime candidates for targeted interventions to reduce the likelihood of sustained opioid use after TJA.

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