Clinical Course of Acute Maxillary Sinusitis Documented by Sequential MRI Scanning

1994 ◽  
Vol 8 (1) ◽  
pp. 19-28 ◽  
Author(s):  
Donald A. Leopold ◽  
Chester T. Stafford ◽  
Earl W. Sod ◽  
Nikolaus M. Szeverenyi ◽  
Jerry D. Allison ◽  
...  
Keyword(s):  
Maxillary Sinus ◽  
Clinical Symptoms ◽  
Maxillary Sinusitis ◽  
Nasal Congestion ◽  
Nasal Discharge ◽  
Tissue Fluid ◽  
Volume Percentage ◽  
Mri Scans ◽  
Mucosal Changes ◽  
A Prospective Study

A prospective study was designed to assess clinical and mucosal changes that occur during resolution of acute maxillary sinusitis. Thirteen previously healthy subjects with symptoms of acute sinusitis and radiographic opacification of at least one maxillary sinus were entered into the study and treated with amoxicillin/clavulinate potassium. Assessment of clinical symptoms, clinical examination, and magnetic resonance imaging (MRI) of the maxillary sinuses were performed at baseline and at days 3, 7, 10, 14, 21, 28 and 56 after initiation of therapy. The T2 values from the MRI scans were analyzed to approximate the more viscous and more fluid-like components of the maxillary sinus contents. After three days of antibiotic therapy, there was marked improvement in facial tenderness, thickness of nasal discharge, volume of nasal discharge, headache, and nasal congestion. Ten to 14 days of treatment were required, however, for improvement in nasal patency. MRI analysis of the volume percentage of air in the involved sinuses showed that by 10 days, only half of the opacification (fluid and thickened mucosa) had resolved. By 56 days, the sinuses were only about 80% aerated. This improvement was attributed mainly to resolution of the more fluid-like component. This study shows that: (1) tissue/fluid changes in sinusitis can be followed with MRI, and (2) although treatment of acute maxillary sinusitis generally results in clinical resolution of symptoms within one week, mucosal changes can persist for 8 weeks or more.

Symptoms in patients with maxillary sinus carcinoma

1990 ◽  
Vol 104 (7) ◽  
pp. 557-559 ◽  
Author(s):  
M. Miyaguchi ◽  
S. Sakai ◽  
N. Mori ◽  
S. Kitaoku
Keyword(s):  
Maxillary Sinus ◽  
Chronic Sinusitis ◽  
Nasal Discharge ◽  
Initial Examination ◽  
Delay In Diagnosis ◽  
Tumour Extension ◽  
First Onset ◽  
Mri Scans ◽  
Ct And Mri

AbstractSymptoms at first onset and on initial examination were analyzed in 845 patients with maxillary sinus carcinoma. About 20–30 per cent of the patients became aware of swelling of cheek, nasal obstruction, nasal discharge and epistaxis as first symptoms. About 50–80 per cent of the patients complained of such symptoms on initial examination. Symptoms of maxillary sinus carcinoma are similar to those of chronic sinusitis which results in a delay in diagnosis. Such symptoms should be recognized to improve survival rate. CT and MRI scans are useful for early diagnosis and determination of tumour extension. Sinoscopy with biopsy is most important to detect the earliest tumour stage.

scholarly journals Prevalence and clinical profile of patients with chronic fungal maxillary sinusitis

2019 ◽  
Vol 5 (2) ◽  
pp. 280
Author(s):  
Vijay Gupta ◽  
Arindam Gupta
Keyword(s):  
Fungal Infection ◽  
Maxillary Sinus ◽  
Paranasal Sinus ◽  
Fungal Infections ◽  
Maxillary Sinusitis ◽  
Clinical Profile ◽  
Chronic Maxillary Sinusitis ◽  
High Index Of Suspicion ◽  
A Prospective Study

<p class="abstract"><strong>Background:</strong> Fungal paranasal sinus disease is considered to be rare but there has been a marked increase in the number and diversity of reported cases of fungal infections of maxillary sinus in recent years. Objectives were to study the incidence of fungal infection in case of chronic maxillary sinusitis, to identify specific type of fungus involved in maxillary sinus infection and to study clinical profile of the patients with fungal infections of maxillary sinus.</p><p class="abstract"><strong>Methods:</strong> A prospective study of was conducted involving the patients attending outpatient department of Otorhinolaryngology, who were clinically and radiologically proved cases of chronic maxillary sinusitis. Patients diagnosed with underlying paranasal sinus malignancies were excluded from the study. 70 patients of chronic maxillary sinusitis were included in the study. Isolates were identified based on colonial and microscopical morphology. Subcultures were done and slide cultures were prepared to identify the fungi.  </p><p class="abstract"><strong>Results:</strong> Fungus was cultured from 12.8% of patients suffering from chronic maxillary sinusitis. The most frequent victims of the disease were young persons in the second decade of life. All patients found positive for fungus had unilateral maxillary sinusitis. <em>Aspergillus niger, Aspergillus fumigatus, Candida albicans</em> and <em>Mucormycosis</em> were the various fungi isolated from cultures of antral washings.</p><p class="abstract"><strong>Conclusions:</strong> The results of the study emphasise the role of fungi as important pathogens of chronic maxillary sinusitis. There must be high index of suspicion of fungal infection when a young adult with a unilateral antral opacity on X-ray with frank pus in antral washings.</p><p> </p>

scholarly journals Hypertrophy of adenoid vegetation: causes and methods of treatment

2019 ◽  
pp. 63-66
Author(s):  
Svetlana Yaremchuk
Keyword(s):  
Food Allergy ◽  
Nasal Congestion ◽  
Specific Ige ◽  
Nasal Discharge ◽  
Food Allergens ◽  
Nasal Breathing ◽  
Breathing Disorders ◽  
Screening Study ◽  
A Prospective Study ◽  
Methods Of Treatment

Topicality: Nasal congestion, nasal breathing disorders and nasal discharge are the most common complaints that parents of ill children refer to an otolaryngologist and pediatrician. The prevalence of allergic pathology in patients with adenoid vegetation hypertrophy (AН) varies from 22 to 73% according to various authors. Aim: To determine the prevalence of allergic rhinitis among patients with hypertrophy of adenoid vegetations, a prospective study was conducted. Materials and methods: 50 children with hypertrophy of adenoid vegetation aged 4 to 14 years were examined. A comprehensive screening study to detect specific IgE sensitization to the most common inhalation and food allergens. Results: Sensitization to inhaled allergens was detected in 48% of cases. In 8% of cases it coincided with food with food allergy. Only food allergy was detected in 1 child (2%). Timely etiopathogenetic therapy with topical nasal corticosteroids in patients with AN will avoid relapses after adenoidectomy and normalize nasal breathing, and in some cases, avoid surgery.

scholarly journals Chronic maxillary sinusitis: Clinical and microbiological evaluation

2012 ◽  
Vol 7 (2) ◽  
pp. 17-22
Author(s):  
D Shrestha ◽  
LK Yadav ◽  
P Thapa
Keyword(s):  
Maxillary Sinusitis ◽  
Antibiotic Sensitivity ◽  
Nasal Discharge ◽  
Medical Sciences ◽  
Sensitivity Testing ◽  
Presenting Symptoms ◽  
Single Organism ◽  
Common Sign ◽  
One Year ◽  
A Prospective Study

Chronic sinusitis essentially results from untreated or inadequately treated acute sinusitis. Sinusitis is one of the common health problems worldwide. This is a prospective study, done in Department of ENT Bir Hospital Kathmandu. The study period was one year from 14 March 2009 to 15 March 2010. In this study the most commonly involved group is 21–30years (44%). The most presenting symptoms was Nasal discharge 46(92%) and nasal obstruction 44(88%). The most common sign was mucopus in nasal cavity in 44(88%) cases followed by post nasal drip in 39(78%) cases. The bacteria most frequently isolated from sinus aspirates were staphylococcus aureus 18(36%) and streptococcus pneumonia 16(32%). Majority of the aspirates 34(68%) cases yielded single organism. The antibiotic sensitivity testing showed that 48(96%) cases of isolates were sensitive to Cephalexin and ceftriaxone.Journal of College of Medical Sciences-Nepal, 2011, Vol-7, No-2, 17-22DOI: http://dx.doi.org/10.3126/jcmsn.v7i2.6675

scholarly journals Rhino-maxillary aspergillosis in an immunocompetent patient. Case report.

2019 ◽  
Vol 6 (2) ◽  
pp. 50-54
Author(s):  
Sergio Moya ◽  
Mily Yañez ◽  
Cristóbal Palma
Keyword(s):  
Case Report ◽  
Maxillary Sinus ◽  
Antifungal Therapy ◽  
Maxillary Sinusitis ◽  
Poor Response ◽  
Immunocompetent Patient ◽  
Nasal Discharge ◽  
Tissue Destruction ◽  
Non Invasive ◽  
The Right

Introduction: Aspergillosis is the second most frequent opportunistic fungal infection of the paranasal sinuses. It primarily affects the maxillary sinus and occurs mainly in immunocompromised individuals. Infection is caused by inhalation of spores or by an oro-sinusal communication. Aspergillosis is classified into an invasive and non-invasive form or Aspergilloma, which usually affects immunocompetent patients. Violaceous lesions, ulcers, necrosis and tissue destruction can be manifested clinically. Patients may experience pain, paresthesias, increases in the volume of purulent or bloody nasal discharge and congestion. Case report: A 62-year-old female patient, immunocompetent, with a condition evolving for about six years. Condition began after a dental extraction, and consisted of absence of scarring and recurrent episodes of symptomatology suggestive of maxillary sinusitis with poor response to antibiotics. The patient was referred to the maxillofacial care unit, presenting an increase of volume in the right genial region, pain and paraesthesia of infraorbital region. The CT scan showed the presence of a radiopaque foreign body in the right maxillary sinus. A surgical procedure was carried out using the Caldwell-Luc technique and biopsy; the case was diagnosed with Aspergillosis. The patient was treated without antifungal therapy because she had a good immune status. Conclusion: Aspergilloma is the most common form of Aspergillosis in immunocompetent individuals. It is usually diagnosed late, as its clinical picture is similar to bacterial sinusitis. In most cases, patients respond well to surgical treatment, and systemic antifungal therapy is not necessary.

scholarly journals Diagnostic accuracy and predictive value of clinical symptoms for the diagnosis of mild COVID-19

2021 ◽  
Author(s):  
V. Popovych ◽  
I. Koshel ◽  
Y. Haman ◽  
V. Leschak ◽  
R. Duplikhin
Keyword(s):  
Diagnostic Accuracy ◽  
Outpatient Treatment ◽  
Clinical Symptoms ◽  
Nasal Congestion ◽  
Acute Onset ◽  
Nasal Discharge ◽  
Target Groups ◽  
Predictive Values ◽  
Significance Level ◽  
Additional Testing

ObjectiveTo assess the diagnostic accuracy of clinical symptoms and their predictive values in patients with suspected mild COVID-19 and to identify target groups for self-isolation and outpatient treatment without additional testing in the primary health care system.MethodsWe conducted an open-label prospective study in both male and female patients aged 18 to 72 years with suspected mild COVID-19 who were sequentially enrolled in the study. The clinical diagnosis was performed in accordance with the WHO recommendations based on the acute onset of such symptoms as olfactory dysfunction, hyperthermia, myalgia, nasal congestion, nasal discharge, cough, rhinolalia, sore throat, without pneumonia or hypoxia in persons in contact with a confirmed case of COVID-19. The physician assessed clinical symptoms using a 4-point scale. The patient self-assessed clinical symptoms using a ten-point visual analogue scale (VAS). All enrolled patients underwent laboratory testing to confirm the diagnosis of COVID-19.ResultsOf the 120 patients underwent testing, the diagnosis of mild COVID-19 was confirmed in 96 patients and ruled out in 24 patients. When assessing symptoms by a physician according to the correlation analysis, hyperthermia, myalgia, nasal congestion and rhinolalia have a positive predictive value with a significance level of more than 0.6. When self-assessing symptoms by a patient, fever, myalgia and nasal congestion have a diagnostic accuracy with a significance level of more than 0.5. Nasal discharge, cough and sore throat have negative predictive values.DiscussionThe presence of these symptoms in patients with an acute onset of the disease can help to make a clinical diagnosis of coronavirus disease and identify target groups for self-isolation and outpatient treatment without additional testing. Highly suspect asymptomatic patients are not considered as those who have possible mild COVID-19 infection.RegistrationEthics Committee of Ivano-Frankivsk National Medical University, Protocol No. 114/20 as of 21 May 2020.

scholarly journals HUBUNGAN GAMBARAN FOTO WATERS DAN GEJALA KLINIK PADA PENDERITA DENGAN DUGAAN SINUSITIS MAKSILARIS DI RSUP PROF DR. R. D. KANDOU MANADO PERIODE 1 OKTOBER 2012–30 SEPTEMBER 2013

e-CliniC ◽  
2014 ◽  
Vol 2 (1) ◽  
Author(s):  
Ni Kadek Ayu Isyana Wardani
Keyword(s):  
Maxillary Sinus ◽  
Correlation Coefficient ◽  
Paranasal Sinus ◽  
Paranasal Sinuses ◽  
Positive Relationship ◽  
Clinical Symptoms ◽  
Maxillary Sinusitis ◽  
The World ◽  
Minor Disease ◽  
The Relationship

Abstract: Sinusitis is an inflamation of  Mukosa  Paranasal Sinuses in which is determined as the  cause for the distraction of  human's health that often be suffered by human being in the entire of the world. The well-known sinusitis found is maxillary sinusitis and  etmoidalis sinusitis . There are some clinic examination can be done to suspect the existence of maxillary sinus such as anamnesis, physical inspection and radiologi inspection. An inspection through Photo Waters is usually being done to evaluate the infection of  paranasal sinus, giving an appropriate evaluation moreover to the minor disease on kovum sinus. The main purpose of this research is to find out the relationship between the description of photo waters and the clinic symptom on the patients with the suspicious of maxillary sinusitis in RSUP prof. Dr.R.D. Kandou manado period of time 1 october 2013-30 september 2013. This research concerns to the analytic correlatic retrospective. The data is collected from sheet of paper in which shows the symptom clinic of maxillary sinusitis and the result of the description of the Photo Waters. Based on the test of correlation Kendal'tau_b the significant value of (p) = 0,272 > 0,05 and the correlation coefficient (r) = 0,150 in which shows that there is a weak positive relationship with the low test value between the description of Photo Waters and clinic symptom on the patients  suspicious for maxillary sinusitis. Keywords: Maxillary sinusitis, Clinical symptoms, Photo Waters   Abstrak: Sinusitis adalah inflamasi mukosa sinus paranasal yang dianggap sebagai salah satu  penyebab  gangguan kesehatan tersering diseluruh dunia. Sinusitis yang paling sering di temukan ialah sinusitis maksilaris dan sinusitis etmoidalis. Ada berbagai pemeriksaan klinik yang dapat dilakukan  untuk mencurigai adanya sinusitis maksilaris seperti anamnesis, pemeriksaan fisik dan pemeriksaan  radiologi. Pemeriksaan Foto Waters adalah pemeriksaan yang paling sering digunakan untuk   mengevaluasi infeksi sinus paranasal, memberikan evaluasi yang tepat meskipun pada kelainan  ringan  pada kavum sinus. Tujuan penelitian ini adalah mengetahui hubungan gambaran Foto Waters dan  gejala klinik pada penderita dengan dugaan sinusitis maksilaris di RSUP Prof DR. R. D. Kandou  Manado Periode 1 Oktober 2012–30 September 2013. Penelitian ini adalah penelitian analitik  korelatik  retrospektif. Data berupa lembaran gejala klinik sinusitis maksilaris dan hasil gambaran Foto Waters. Berdasarkan uji korelasi Kendall'tau_b nilai signifikan (p) = 0,272 > 0,05 dan koefisien  korelasi (r) = 0,150  yang berarti bahwa ada hubungan positif lemah dengan nilai kemaknaan yang rendah antara gambaran  Foto Waters dan gejala klinik pada penderita dengan dugaan sinusitis maksilaris. Kata kunci: Sinusitis maksilaris, Gejala klinik, Foto Waters.

scholarly journals Eicosanoid imbalance correlates in vitro with the pattern of clinical symptoms of Samter's triad

2013 ◽  
Vol 51 (1) ◽  
pp. 61-69
Author(s):  
U. Forster ◽  
S. Strathmann ◽  
D. Schafer ◽  
A.J. Szczepek ◽  
H. Olze
Keyword(s):  
Clinical Symptoms ◽  
Nasal Congestion ◽  
Visual Analogue Score ◽  
Asthma Severity ◽  
Nasal Discharge ◽  
Course Of Disease ◽  
Inflammatory Drugs ◽  
Samter’S Triad ◽  
Peripheral Blood Leucocytes

Background: Hypersensitivity to non-steroidal anti-inflammatory drugs (NSAIDs) is often associated with chronic rhinosinusitis (CRS), nasal polyps (CRSwNP) and asthma, together known as Samter's triad. The disease is characterised by eicosanoid imbalance. In our study, we determined clinical and laboratory parameters in respect of three groups of patients: 1) CRSwNP, 2) CRSwNP and asthma (CRSwNP-A), and 3) CRSwNP with asthma and NSAID-triggered hypersensitivity (CRSwNP-AA). Our main goal was to improve the characterisation of the stages of development in Samter's triad, pointing to the homogeneous or heterogeneous course of disease. Methodology: Forty-three patients (10 CRSwNP, 14 CRSwNP-A, 19 CRSwNP-AA) and 10 control subjects were included in the study. Nasal assessment using the CRS visual analogue score, endoscopy- and computer tomography scores, allergy tests, analysis of sinus surgeries, asthma severity and in vitro functional eicosanoid tests (FET) with peripheral blood leucocytes were performed. Results: The scores reflecting CRS symptoms such as nasal congestion, nasal discharge and smell impairment differed between the patients groups reflecting the severity of disease (CRSwNP-AA > CRSwNP-A > CRSwNP). Eicosanoid imbalance correlated with nasal congestion, nasal discharge and loss of smell. Conclusion: The data presented support the hypothesis of the continuous development of NSAID-triggered hypersensitivity, culminating in Samter's triad.

scholarly journals Schizophyllum Communea Causative Agent of Fungal Sinusitis: A Case Report

2011 ◽  
Vol 2011 ◽  
pp. 1-4 ◽  
Author(s):  
T. Premamalini ◽  
B. T. Ambujavalli ◽  
S. Anitha ◽  
L. Somu ◽  
Anupma J. Kindo
Keyword(s):  
Maxillary Sinus ◽  
Maxillary Sinusitis ◽  
Schizophyllum Commune ◽  
Sinus Surgery ◽  
Banana Peel ◽  
Nasal Discharge ◽  
Fungal Sinusitis ◽  
Maxillary Bone ◽  
Cotton Blue ◽  
The Right

We present a case of maxillary sinusitis caused bySchizophyllum commune, in a 50-year-old female. The patient presented with nasal obstruction, purulent nasal discharge from right side of the nose, cough, headache, and sneezing. Computed tomography revealed extensive opacity of the right maxillary sinus as well as erosion of the nasal wall and maxillary bone. Functional endoscopic sinus surgery was done, and fungal debris present on right side of the maxillary sinus was removed and sent to laboratory. Potassium hydroxide (KOH) examination of the nasal discharge showed hyaline, septate hyphae. Primary isolation on Sabouraud's dextrose agar (SDA) yielded a white woolly mould. Banana peel culture after 8 weeks showed macroscopically visible fan-shaped fruiting bodies. Lactophenol cotton blue (LPCB) mount of the same revealed hyaline septate hyphae, often with clamp connections. Identification was confirmed by the presence of clamp connections formed on the hyphae and by vegetative compatibility with known isolates.

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