scholarly journals Hypertrophy of adenoid vegetation: causes and methods of treatment

2019 ◽  
pp. 63-66
Author(s):  
Svetlana Yaremchuk
Keyword(s):  
Food Allergy ◽  
Nasal Congestion ◽  
Specific Ige ◽  
Nasal Discharge ◽  
Food Allergens ◽  
Nasal Breathing ◽  
Breathing Disorders ◽  
Screening Study ◽  
A Prospective Study ◽  
Methods Of Treatment

Topicality: Nasal congestion, nasal breathing disorders and nasal discharge are the most common complaints that parents of ill children refer to an otolaryngologist and pediatrician. The prevalence of allergic pathology in patients with adenoid vegetation hypertrophy (AН) varies from 22 to 73% according to various authors. Aim: To determine the prevalence of allergic rhinitis among patients with hypertrophy of adenoid vegetations, a prospective study was conducted. Materials and methods: 50 children with hypertrophy of adenoid vegetation aged 4 to 14 years were examined. A comprehensive screening study to detect specific IgE sensitization to the most common inhalation and food allergens. Results: Sensitization to inhaled allergens was detected in 48% of cases. In 8% of cases it coincided with food with food allergy. Only food allergy was detected in 1 child (2%). Timely etiopathogenetic therapy with topical nasal corticosteroids in patients with AN will avoid relapses after adenoidectomy and normalize nasal breathing, and in some cases, avoid surgery.

scholarly journals The effects of nasal breathing on the development of snoring and apnea

2020 ◽  
pp. 89-94
Author(s):  
Svetlana E. Yaremchuk
Keyword(s):  
Sleep Quality ◽  
Nasal Congestion ◽  
Upper Airway ◽  
Case Control Studies ◽  
Nasal Breathing ◽  
Adequate Treatment ◽  
Randomized Controlled ◽  
Breathing Disorders ◽  
Nasal Steroids ◽  
Improve Sleep Quality

Since the nose is the entrance gate of the upper airway, its stuffiness can contribute to sleep disturbance. The results of a number of case-control studies have shown that nasal congestion frequency associated with snoring and mild OSA. However, there is no strong correlation between the degree of nasal obstruction and the severity of OSA. Randomized controlled trials have shown that in patients with rhinitis, both allergic and non-allergic, the use of nasal steroids can improve sleep quality and may be useful for patients with mild OSA, but they themselves are not an adequate treatment. Surgical correction of nasal breathing disorders also reduces the apnea index and improves sleep quality.

scholarly journals The use of nasal decongestants to correction the respiratory and olfactory function of the nose

2019 ◽  
pp. 60-65 ◽  
Author(s):  
S. V. Morozova ◽  
L. A. Toporkova
Keyword(s):  
Nasal Cavity ◽  
Nasal Obstruction ◽  
Paranasal Sinuses ◽  
Nasal Congestion ◽  
Olfactory Function ◽  
Nasal Discharge ◽  
Nasal Breathing ◽  
Nasal Decongestants ◽  
Osteomeatal Complex ◽  
Tube Dysfunction

One of the main functions of the nose is respiratory and olfactory. Difficulty in nasal breathing, nasal congestion, nasal discharge can complicate the respiratory and olfactory functions of the nose or make them impossible. Most often the cause is swelling of the mucous. Nasal obstruction and rhinorrhea are the most common symptoms in diseases of the nasal cavity and paranasal sinuses. Of great importance is the use of local vasoconstrictors to eliminate swelling in the nasal cavity and prevent complications associated with auditory tube dysfunction. It is proved that the use of nasal decongestants helps to reduce swelling in the nasal cavity and in the osteomeatal complex. Otrivin Moisturizing formula, Otrivin Menthol, Otrivin Complex and Otrivin Sea are effective and well tolerated means to eliminate swelling in the nasal cavity and reduce nasal discharge and rehabilitation of olfactory function.

scholarly journals The significance of cow’s milk proteins in the development of IgE-mediated food allergy among children

2019 ◽  
Vol 16 (2) ◽  
pp. 38-44
Author(s):  
S Yu Petrova ◽  
S V Khlgatian ◽  
V M Berzhets ◽  
L A Pishchulina ◽  
A V Vasilyeva
Keyword(s):  
Food Allergy ◽  
Whey Proteins ◽  
Milk Proteins ◽  
Specific Ige ◽  
Moscow Region ◽  
Food Allergies ◽  
Cow’S Milk ◽  
Food Allergens ◽  
Cow's Milk ◽  
Cow’S Milk Proteins

Identification of offending allergens in patients with food allergy is a very important part of an allergist’s activity. Objective. To study the structure оf sensitization to food allergens among children in Moscow and Moscow region and to determine the significance of sensitization to milk proteins . Methods. The level and class of specific IgE in blood serum of children with IgEmediated allergic diseases were examined with RIDA AllergyScreen method. Serum of children with high level of specific IgE to milk allergenic proteins was studied. The level and ratio of specific IgE to individual milk allergens were revealed. Results. The structure of sensitization to food allergens was determined. It was revealed that cow’s milk allergens are the leading triggers of food allergy, especially in early childhood in Moscow and the Moscow region. The features of sensitization to cow’s milk proteins among children were analyzed. Conclusions. According to the study, about half of children with IgEmediated food allergies in Moscow and the Moscow region have sensitization to cow’s milk proteins. The leading role in the frequency of sensitization belongs to whey proteins of milk. Among them sensitization to а-lactalbumin was detected more often. The questions about the selection of hypoallergenic milk formulas for feeding of children with allergy to cow’s milk proteins were discussed.

scholarly journals The potential anti-inflammatory role of adiponectin in food allergy: a case–control study on children

2018 ◽  
Vol 120 (10) ◽  
pp. 1117-1121
Author(s):  
Mahshid Sirjani ◽  
Raheleh Shokouhi Shoormasti ◽  
Nastaran Sabetkish ◽  
Maryam Ayazi ◽  
Nazanin Khodayari Namini ◽  
...  
Keyword(s):  
Food Allergy ◽  
Patient Group ◽  
Caesarean Section Rate ◽  
Clinical History ◽  
Serum Levels ◽  
Specific Ige ◽  
Control Group ◽  
Food Allergens ◽  
Group I ◽  
Group Ii

AbstractWe aimed to assess the possible relationship between food allergy and two key adipokines – leptin and adiponectin – in children with food allergy. A total of forty patients with definite diagnosis of food allergy according to clinical history and specific IgE (sIgE) for food allergens (group I) were enrolled in this pilot study. The control group (group II) included thirty children with no evidence of allergic symptoms. Serum levels of leptin and adiponectin were measured by ELISA. Meanwhile, sIgE was measured for the eight most common food allergens by the immunoblot method in all participants. The median ages in groups I and II were 18·5 and 23·5 months, respectively. The respective Caesarean section rate was 64·9 and 16·7 % in groups I and II (P<0·001). Serum levels of adiponectin were significantly higher in the patient group compared with controls (24·11 (sd12·14)v. 10·67 (sd12·23) μg/ml,P<0·001), whereas no statistically meaningful difference was detected in serum leptin concentrations (P=0·92). There was a significant inverse relationship between age and adiponectin levels in group I (P=0·002,r–0·479) and group II (P=0·04,r–0·365), and it was more significant in group I. The most common allergens in the patient group were wheat (52·5 %), hazelnut (52·5 %), cow’s milk (50 %) and egg white (30 %). The results of this study suggest an essential link between adiponectin and food allergy that is probably unlikely to be affected by obesity as a confounding factor.

Clinical Course of Acute Maxillary Sinusitis Documented by Sequential MRI Scanning

1994 ◽  
Vol 8 (1) ◽  
pp. 19-28 ◽  
Author(s):  
Donald A. Leopold ◽  
Chester T. Stafford ◽  
Earl W. Sod ◽  
Nikolaus M. Szeverenyi ◽  
Jerry D. Allison ◽  
...  
Keyword(s):  
Maxillary Sinus ◽  
Clinical Symptoms ◽  
Maxillary Sinusitis ◽  
Nasal Congestion ◽  
Nasal Discharge ◽  
Tissue Fluid ◽  
Volume Percentage ◽  
Mri Scans ◽  
Mucosal Changes ◽  
A Prospective Study

A prospective study was designed to assess clinical and mucosal changes that occur during resolution of acute maxillary sinusitis. Thirteen previously healthy subjects with symptoms of acute sinusitis and radiographic opacification of at least one maxillary sinus were entered into the study and treated with amoxicillin/clavulinate potassium. Assessment of clinical symptoms, clinical examination, and magnetic resonance imaging (MRI) of the maxillary sinuses were performed at baseline and at days 3, 7, 10, 14, 21, 28 and 56 after initiation of therapy. The T2 values from the MRI scans were analyzed to approximate the more viscous and more fluid-like components of the maxillary sinus contents. After three days of antibiotic therapy, there was marked improvement in facial tenderness, thickness of nasal discharge, volume of nasal discharge, headache, and nasal congestion. Ten to 14 days of treatment were required, however, for improvement in nasal patency. MRI analysis of the volume percentage of air in the involved sinuses showed that by 10 days, only half of the opacification (fluid and thickened mucosa) had resolved. By 56 days, the sinuses were only about 80% aerated. This improvement was attributed mainly to resolution of the more fluid-like component. This study shows that: (1) tissue/fluid changes in sinusitis can be followed with MRI, and (2) although treatment of acute maxillary sinusitis generally results in clinical resolution of symptoms within one week, mucosal changes can persist for 8 weeks or more.

scholarly journals Aspects of differential diagnosis and treatment of rhinitis in children under 2 years of age

2021 ◽  
pp. 72-77
Author(s):  
S. A. Karpishchenko ◽  
O. Е. Vereshchagina ◽  
E. O. Teplova
Keyword(s):  
Young Children ◽  
Nasal Cavity ◽  
Psychological Health ◽  
Nasal Congestion ◽  
Isotonic Saline ◽  
Clinical Manifestations ◽  
Differential Diagnostics ◽  
Nasal Discharge ◽  
Nasal Breathing ◽  
Breathing Difficulty

Introduction. Clinical manifestations of rhinitis have a negative impact not only on the physical, social, and psychological health of children, but also on their parents, especially in families with a first child. Nasal congestion, nasal breathing difficulty cause problems with sleep and feeding.Aim of the study. To estimate the occurrence of rhinitis in children under two years old in the outpatient practice of otorhinolar-yngologists, to consider features of the course and differential diagnostics of various rhinitis types, to evaluate the effectiveness of nasal irrigation-elimination therapy in the treatment of acute rhinitis symptoms.Materials and Methods. Between September 2020 and July 2021, 220 patients between 0 to 18 years were managed: preschool-aged patients comprised 120 patients (54.5%), of whom 27 patients under two years old had symptoms of rhinitis, including those with symptoms lasting more than two weeks.Results. Among the patients referred to us, infectious rhinitis was diagnosed in the majority of cases - in 18 patients (66,7%), which can be explained not only by the timing of the study but also by the highest prevalence of this pathology among the diseases of the nasal cavity. Allergic and non-allergic rhinitis occurred in only 4 (14.8%) and 5 (18.5%) persons, respectively. Symptomatic irrigation therapy with saline solutions is just as necessary for young children as it is for older children and adults. Some difficulties in nasal cavity care during rhinitis are the anatomical narrowness of the nasal passages and lack of blowing skills in young children. In these situations, preference should be given to gentle, non-traumatic, gentle aspiration with prior irrigation of the nasal cavity with an isotonic saline solution. When a nasal aspirator was used, there was a decrease in the duration of nasal discharge during the illness and a reduction in the duration of the disease.Conclusion. Rhinitis in young children is a common but underestimated problem. Clinical manifestations are more often associated with typical symptoms: nasal congestion, discharge, nasal breathing difficulty, and sneezing. The use of irrigation-elimination intranasal therapy with the use of a nasal cavity aspirator can reduce the timing of clinical symptoms of rhinitis and reduce the overall duration of the disease.

ЗНАЧЕНИЕ БЕЛКОВ КОРОВЬЕГО МОЛОКА В РАЗВИТИИ IGE-ОПОСРЕДОВАННОЙ ПИЩЕВОЙ АЛЛЕРГИИ У ДЕТЕЙ

2019 ◽  
Author(s):  
S.Yu. Petrova ◽  
S.V. Khlgatian ◽  
V.M. Berzhets ◽  
L.A. Pishchulina ◽  
A.V. Vasilyeva
Keyword(s):  
Food Allergy ◽  
Whey Proteins ◽  
Milk Proteins ◽  
Allergic Diseases ◽  
Specific Ige ◽  
Moscow Region ◽  
Food Allergies ◽  
Food Allergens ◽  
Leading Role ◽  
High Level

ПЕТРОВАС.Ю.1,ХЛГАТЯН С.В.1,БЕРЖЕЦ ВАЛЕНТИНА МИХАЙЛОВНА1,ПИЩУЛИНАЛ.А.1,ВАСИЛЬЕВАА.В.1 1ФГБНУ НИИВС им. И.И. Мечникова Цель. Изучить структуру сенсибилизации к пищевым аллергенам у детей в Москве и Московской области и определить в ней место сенсибилизации к белкам молока. Материалы и методы. Методом RIDA AllergyScreen регистрировали концентрацию и класс аллерген-специфических IgE в сыворотках крови детей с IgE-опосредованными аллергическими заболеваниями. Исследовали сыворотки детей с высоким титром аллерген-специфических IgE к белкам - аллергенам молока. Выявляли уровень и соотношение аллерген-специфических IgE к отдельным аллергенам молока. Результаты. Определена структура сенсибилизации к пищевым аллергенам. Выявлено, что аллергены коровьего молока являются ведущими триггерами пищевой аллергии, особенно в раннем детском возрасте, в Москве и Московской области. Проанализированы особенности сенсибилизации к белкам коровьего молока у детей. Заключение. По данным исследования, около половины детей с IgE-опосредованной пищевой аллергией в Москве и Московской области имеют сенсибилизацию к белкам коровьего молока. Ведущая роль по частоте встречаемости сенсибилизации принадлежит сывороточным белкам молока. Из них наиболее часто выявляли сенсибилизацию к а-лактальбумину. Обсуждены вопросы подбора гипоаллергенных молочных смесей при аллергии к белкам коровьего молока у детей.Identification of offending allergens in patients with food allergy is a very important part of an allergists activity. Objective. To study the structure оf sensitization to food allergens among children in Moscow and Moscow region and to determine the significance of sensitization to milk proteins . Methods. The level and class of specific IgE in blood serum of children with IgEmediated allergic diseases were examined with RIDA AllergyScreen method. Serum of children with high level of specific IgE to milk allergenic proteins was studied. The level and ratio of specific IgE to individual milk allergens were revealed. Results. The structure of sensitization to food allergens was determined. It was revealed that cows milk allergens are the leading triggers of food allergy, especially in early childhood in Moscow and the Moscow region. The features of sensitization to cows milk proteins among children were analyzed. Conclusions. According to the study, about half of children with IgEmediated food allergies in Moscow and the Moscow region have sensitization to cows milk proteins. The leading role in the frequency of sensitization belongs to whey proteins of milk. Among them sensitization to а-lactalbumin was detected more often. The questions about the selection of hypoallergenic milk formulas for feeding of children with allergy to cows milk proteins were discussed.

Total IgE, Specific IgE and Prick-Tests Against Foods in Common Migraine—A Prospective Study

Cephalalgia ◽  
1983 ◽  
Vol 3 (4) ◽  
pp. 231-234 ◽  
Author(s):  
A. Pradalier ◽  
S. Weinman ◽  
J. M. Launay ◽  
J. F. Baron ◽  
J. Dry
Keyword(s):  
Prospective Study ◽  
Low Frequency ◽  
Food Challenge ◽  
Specific Ige ◽  
Food Allergens ◽  
Total Ige ◽  
Very Low Frequency ◽  
Common Food ◽  
Class 1 ◽  
A Prospective Study

A prospective study of total IgE, specific IgE against 12 common foods, and prick-tests with 11 common food allergens was performed on 50 consecutive migraine sufferers. Total IgE levels were found above 100 kU/I for seven patients, but five of them were atopic. Prick-tests and PAST were positive for four and six patients (class 1), respectively. Food challenge on these six patients did not cause any migraine attacks. This study thus indicates a very low frequency of allergic dietary migraine to common foods.

Food allergy

2018 ◽  
Author(s):  
John Puntis
Keyword(s):  
Food Allergy ◽  
Nasal Congestion ◽  
Skin Prick Testing ◽  
Clinical History ◽  
Specific Ige ◽  
Cow Milk ◽  
Severe Reaction ◽  
Detailed Clinical History ◽  
Food Challenges ◽  
Food Specific Ige

Food allergy is an immune response to food that can be classified as immunoglobulin (Ig)-E and non-IgE mediated. Milk, egg, peanut, tree nuts, and fish are among the most prevalent causes of food allergy. Mild reactions can include itchy rash, watering eyes, and nasal congestion while a severe reaction results in anaphylaxis. A detailed clinical history is essential when making a diagnosis, and skin prick testing and quantitative measurement of food-specific IgE antibodies can be helpful. Cow milk protein allergy causes a plethora of symptoms and frequently resolves spontaneously over the first 2 years of life; diagnosis is based mainly on clinical history. Food challenges have a pivotal role in the diagnosis of food allergy. Introduction of ‘allergic’ foods at 3–6 months alongside continuing breastfeeding may prevent allergy.

scholarly journals New approaches in diagnostics of food allergy and effectiveness of dietotherapy in infants

2009 ◽  
Vol 7 (3) ◽  
pp. 30-42
Author(s):  
T Ae Borovick ◽  
S G Makarova ◽  
N N Semenova ◽  
S N Darchia ◽  
L V Shumilina ◽  
...  
Keyword(s):  
Food Allergy ◽  
Enzyme Assay ◽  
Diagnostic System ◽  
Specific Ige ◽  
Baby Food ◽  
Food Allergens ◽  
New Approaches ◽  
Efficacy Assessment

In the article the modern approaches to diagnostics of food allergy with the focus on other thenlgE-related forms of gastrointestinal hypersensitivity in infants are described. The results of the own study on efficacy assessment of new diagnostic system - immune-enzyme assay «Lactest» for specific IgE and IgG levels against food allergens as well as proteins from baby food estimation in sera of infants are presented. Dietotherapy for infants with food allergy based on immune-enzyme assay «Lactest» is described.

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