Patients with purulent necrotic wounds treatment using by intravenous laser blood irradiation (405 nm)

Objective: to analyze the effectiveness of purulent-necrotic wounds management using intravenous laser irradiation of blood (405nm). Materials and methods. Object of study – patients with purulent-necrotic wounds. Clinical studies and analysis of the intravenous laser blood irradiation (405 nm) effect on the wound healing process and on the healing speed of purulent soft tissues wounds in patients with type 2 diabetes mellitus were carried out. Results. It was found that the use of intravenous laser blood irradiation (405 nm) is a highly effective method for the treatment of purulent soft tissues wounds, which allows to reduce the number of complications and shorten the time for complete epithelization of purulent wounds by 7–10 days compared with traditional treatment.

Download Full-text

EFEKTIFITAS MODERN DRESSING TERHADAP PROSES PENYEMBUHAN LUKA DIABETES MELITUS TIPE 2

Jurnal Kesehatan ◽

10.38165/jk.v10i1.7 ◽

2020 ◽

Vol 10 (1) ◽

pp. 1273-1284

Author(s):

Endang Subandi ◽

Kelvin Adam Sanjaya

Keyword(s):

Diabetes Mellitus ◽

Assessment Tool ◽

Wound Care ◽

Healing Process ◽

Wilcoxon Test ◽

Control Group ◽

Wound Healing Process ◽

P Value ◽

Wound Assessment

Luka Diabetes merupaka luka kronis yang susah disembuhakan. Luka diabetes berasal dari komplikasi penyakit diabetes. Luka diabetes sebagian besar dilakukan tindakan amputasi dan memiliki dampak kepada psikologi pasien. Sudah lama perawatan luka menggunakan konvensional yang memiliki kekurangan, seperti: menimbulkan rasa nyeri, menimbulkan luka baru, resiko infeksi lebih tinggi. Metode yang baru teknik perawatan luka modern dressing dimana luka akan dibuat moisture balance atau lembab karena akan memfasilitasi chemokines dan cytokines untuk pertumbuhan sel pada luka. Penelitian ini bertujuan untuk mengetahui efektifitas modern dressing terhadap proses penyembuhan luka diabetes mellitus tipe 2. Jenis penelitian menggunakan Pre-Postest With Control Group Desain terhadap suatu kelompok. Pengambilan sampel menggunakan accidental sampling dengan jumlah sampel sebanyak 15 responden intervensi dan kontrol. Pengumpulan data dilakukan dengan observasi, Instrument penelitian yang digunakan lembar observasi Betes-Jensen Wound Assessment Tool (BWAT). Penelitian dilakukan selama 45 hari. Analisa data yang digunakan adalah uji shapiro-wilk. Data analisa dengan uji statistik Wilcoxon test. Hasil penelitian didapatkan ada perbedaan skor luka sebelum dan sesudah pada kelompok pada kelompok perlakuan dengan p-value =0.005 (≤ 0.05) dan pada kelompok kontol dengan p-value =1.000 (≥ 0,05). Lalu hasil uji beda antar kelompok dengan p-value=0,001(≤ 0,05). Jadi dapat disimpulkan bahwa modern dressing memiliki efektifitas terhadap proses penyembuhan luka diabetes bellitus tipe 2.Kata kunci: Luka, DM Tipe 2, Modern Dressing ABSTRACTDiabetic wound are the chronic wounds that are difficult to cure. Diabetic wounds originate from complications of diabetes mellitus. Diabeteic wound are mostly implementation is amputation and have impact on the psychology of patients. Long time a wound treatment has deficiencies, causes pain, raises new wound, high risk of infection. New methods of modern dressing wound care tecniques where wound will be made moisture balance or moiist because it will facilitate chemokines and cytokines for cell growth in wounds. Therefore this study aims to determine the effectiviness of modern dressing on the wound healing process of type 2 diabetes mellitus. This type of research uses the Pre Postest With Control Group Desig for a sampling group conducted at Cirebon Wound Care Center using accidental sampling. The samples was 15 respondents treatments and control. Research instrument used were sheets observation Betes Jensen Wound Assessment Tool. The Study was conducted for 45 days. The data analysis used is the shapiro wilk test and data analysis sattistic with wilcoxon test. The result are obtained before and after in the treatment group with p value=0.005 (≤ 0.05 and in the control group with p value =1.000 (≥ 0,05). Then the result of different test between groups with a p value =0,001(≤ 0,05).The conclusion is a modern dressing has the effectiviness of the wound healing process of type 2 diabtes mellitus.Kata kunci: Diabetic Wound, Type 2 Diabetes Mellitus, Modern Dressing

Download Full-text

PHOTODYNAMIC THERAPY EFFECTS ON MICROFLORA IN THE TREATMENT OF PURULATORY-NECROTIC PROCESSES OF SOFT TISSUES (CLINICAL AND EXPERIMENTAL WORK)

Kharkiv Surgical School ◽

10.37699/2308-7005.2.2020.05 ◽

2020 ◽

pp. 26-29

Author(s):

Y. D. Khvorostov ◽

S. O. Morozov ◽

H. M. Herasymov ◽

V. V. Derikolenko ◽

S. S. Solodovidchenko

Keyword(s):

Wound Healing ◽

Photodynamic Therapy ◽

Experimental Work ◽

Soft Tissues ◽

Healing Process ◽

Wound Healing Process ◽

Complex Treatment ◽

Bacterial Composition ◽

Purulent Wounds ◽

Treatment Of Wounds

Summary. The effect of PDT on the wound healing process and the Bacterial composition of wounds has not been fully studied. Material and methods. The effects of PDT of various wavelengths on the most common microflora of purulent wounds and the course of the wound process are investigated. Results and discussion. The application of PDT increased the sensitivity of microflora to ABD, and also stimulated reparative processes — the growth of granulation tissue and marginal epithelization. Conclusions. The application of PDT in the complex treatment of wounds favorably affects wound healing, expanding the possibilities of AB therapy

Download Full-text

Complex treatment of experimental purulent wound of soft tissues

Klinicheskaia khirurgiia ◽

10.26779/2522-1396.2020.7-8.58 ◽

2020 ◽

Vol 87 (7-8) ◽

pp. 58-62

Author(s):

О. V. Lihonenko ◽

О. V. Storozhenko ◽

А. B. Zubakha ◽

І. А. Shumeiko ◽

І. О. Chorna

Keyword(s):

Wound Healing ◽

Soft Tissues ◽

Healing Process ◽

Laboratory Animals ◽

Wound Healing Process ◽

Complex Treatment ◽

Wound Area ◽

Purulent Wounds ◽

Purulent Wound ◽

The Impact

Objective. To study the impact of estrogens and liposomes on course of healing process in purulent wounds of soft tissues in experiment. Маterials and methods. Еxperimental investigation was done on 21 sheep. In the laboratory animals purulent-inflammatory process was simulated. Тhe laboratory animals were distributed into two groups: a control - 6 sheep and investigated - 15. All the animals obtained conventional therapy. In laboratory animals of the investigated group estrogens and liposomes were added to complex of the conventional treatment measures. The healing process course was controlled, using cytological, biochemical, planimetric and mathematic-statistical methods of investigation. Results. Application of combined estrogen-liposomal therapy in complex treatment of experimental purulent wound of soft tissues have enhanced the levels of оxyprolene, ribonucleic and deoxyribonucleic acids in the wound area, raised a value of estradiol/testosteronic index, accelerated the wound cleansing, the granulations creation and shortened the wound healing process by (2.12 ± 0.24) days. Conclusion. Including of estrogens and liposomes into the treatment complex for experimental purulent wound of soft tissues enhances cellular biosynthetic activity, activity of reparative processes in the wound area, accelerates the wound cleansing and the granulation creation, shortens the wound healing process and may be applied for improvement of the purulent wounds treatment in elderly and senile patients.

Download Full-text

Type 2 Diabetes Mellitus (T2DM): Biological Overview from Pathways to Organelles and its Translation toward a Torpid Wound Healing Process

Journal of Diabetes & Metabolism ◽

10.4172/2155-6156.1000285 ◽

2013 ◽

Vol 04 (07) ◽

Author(s):

Pedro López-Saura Gerardo Guillen-Nieto ◽

Boris Acevedo-Castro Luis Herrera-Martínez

Keyword(s):

Diabetes Mellitus ◽

Type 2 Diabetes ◽

Wound Healing ◽

Type 2 Diabetes Mellitus ◽

Healing Process ◽

Wound Healing Process

Download Full-text

Comparison of the effect of collagen (amino acid) and amnion (proteinase inhibitor) on the wound healing of soft tissues

Padjadjaran Journal of Dentistry ◽

10.24198/pjd.vol22no1.14067 ◽

2010 ◽

Vol 22 (1) ◽

Author(s):

Weko Adhiarto ◽

Sunardhi Mangundjaja ◽

Makmuri Yusuf ◽

Bambang Pontjo

Keyword(s):

Wound Healing ◽

Amino Acid ◽

Soft Tissue ◽

Collagen Synthesis ◽

Soft Tissues ◽

Proteinase Inhibitors ◽

Healing Process ◽

Control Group ◽

Wound Healing Process ◽

The Mean

The wound healing process of the soft tissue aims to accelerate the closing of the wound by recurring, restoring the function, and minimizing the scar tissue. This process has to occur in the surgery process to obtain better-wound healing. The aim of this study was to know the stimulation effect of the wound dressing to accelerate the wound healing process of the soft tissue using Collagen (amino acid) and Amnion (proteinase inhibitors). This true experimental study was done to 36 mice (Sprague Dawley) that were divided into three different groups, two groups were the treatment groups and one group was the control group. Each group was adapted in Pathology Laboratory of Faculty of Veterinary Medicine Bogor Agricultural University. All of the mice were injured on the skin by incising the right side of the back for 2 cm in length and 4 mm in depth and then cleaned with 0.9% NaCl solution. To the first group of treatment, the wound was applicated by Amnion, and the second group was applicated by Collagen. Each 4 mice of all group were a termination by ether and encryption on the wounded tissue was conducted on day 3rd, 7th, and 14th. Assessment for a number of fibroblast and collagen synthesis on the wound of back tissue was conducted with the histological examination by painted using hematoxylin-eosin. The results concluded that Collagen application was influencing the mean of fibroblast higher than Amnion, and the lowest was controlled with statistically significant. The mean of collagen used Collagen lower than Amnion, and the lowest was control with statistically significant. It could be concluded that collagen application was preeminent in increasing the productivity of the fibroblast, as well as in developing forms of the collagen synthesis compared with Amnion and control.

Download Full-text

EFFECTIVITY OF INDONESIAN HONEY ON DIABETIC FOOT ULCERS HEALING PROCESS: OBSERVATIONAL CASE STUDY

International Journal of Nursing and Health Services (IJNHS) ◽

10.35654/ijnhs.v2i2.88 ◽

2019 ◽

Vol 2 (2) ◽

pp. 20-28

Author(s):

Anita Sukarno ◽

Nur Hidayah ◽

Musdalifah Musdalifah

Keyword(s):

Diabetic Foot ◽

Healing Process ◽

Cost Effective ◽

Tissue Type ◽

Foot Ulcers ◽

Wound Healing Process ◽

Diabetic Foot Ulcers ◽

Necrotic Tissue

Background: Diabetic foot ulcers were common diabetes complication that progressively growth globally. The effectivity of Manuka honey in wound healing process was huge published currently. Modern dressing and Manuka honey may not affordable and cost effective since these dressings were not produced originally in Indonesia. In addition, the published study of Indonesian honey is still lack. Therefore, we conducted this study to investigate the effectivity of Indonesian honey in diabetic foot ulcers healing process. Method: This study design was observational case study. This study was conducted among type 2 diabetes with diabetic foot ulcers in Griya Afiat Homecare and ETN Center in Makassar City, Indonesia from March to June 2014. The Bates Wound Assessment Tool (BWAT) were used to collect the score of diabetic foot ulcer healing process regarding wound size, depth, edges, undermining, necrotic tissue type, necrotic amount, granulation, epithelization, exudate type and amount, surrounding skin color, edema and induration. Descriptive, Independent t-test, Analysis of Variance (ANOVA) and Wilcoxon signed rank test were conducted appropriately. Results: In total, 10 type 2 diabetes patients with diabetic foot ulcers were participated. The factors associated with wound healing process were diabetes treatment (t= 2.44, p= 0.041) and primary dressing (t= -2.76, p= 0.025). The effect of honey primary dressing was in reducing wound size (p= 0.043), improving necrotic tissue type (p= 0.041), reducing necrotic tissue amount (p= 0.042), increasing granulation (p= 0.038) and epithelization (p= 0.042). In the counterpart, the effect of modern dressing was in improving necrotic tissue type (p= 0.046) and increasing granulation (p= 0.042). Conclusion: Indonesian honey is beneficial on diabetic foot ulcers healing process. Recommendation: Therefore, findings suggest that honey should be considered as the alternative, cost effective and beneficial wound dressing on the diabetic foot ulcers.

Download Full-text