Extraskeletal Osteosarcoma of Colon Mimicking Carcinoma of Colon – A Rare Entity

2020 ◽  
Vol 2 ◽  
pp. 73-76
Author(s):  
Birma Ram ◽  
Pankaj Sharma ◽  
Manoj Gopinath ◽  
Shamresh Kumar Singh

Extraskeletal osteosarcoma is a rare malignant mesenchymal tumor which typically affects elderly patients and the commonly affected sites are extremities, retroperitoneum, mesentery, and trunk. Extraskeletal osteosarcoma arising from colon or retroperitoneum can manifest as a large mass with features of intestinal or urinary tract obstruction. Local recurrence after excision and distant metastasis are common, so regular follow-up and surveillance of such patients are advisable after excision of the primary tumor.

2017 ◽  
Vol 4 (suppl_1) ◽  
pp. S349-S349 ◽  
Author(s):  
Hanine El Haddad ◽  
George Viola ◽  
Ying Jiang ◽  
Issam Raad ◽  
Kenneth V Rolston ◽  
...  

Abstract Background Percutaneous nephrostomy tubes (PCN) are indicated for relief of urinary tract obstruction. These devices are prone to mechanical and infectious complications. The infection rate at 90 days is ±20%. Our objective was to determine whether discordant antimicrobial coverage provided prior to PCN exchange was associated with a higher rate of recurrent infection compared with those who received concordant therapy. Methods We retrospectively reviewed 780 patients that had undergone initial PCN placement at our institution between July 2014 and February 2017. We only included patients that had developed a definite PCN infection, subsequent PCN exchange, with a minimum 30 day post-PCN exchange follow up. We defined PCN infection as the presence of a positive urine culture (≥104 cfu/mL) plus symptoms consistent with a urinary tract infection. Recurrence was defined as a new PCN infection with the isolation of the same organism to the initial episode. Antibiotics were defined as concordant if they had activity against all organisms’ isolated based on antimicrobial susceptibilities. Results A total of 47 patients met our inclusion criteria. The median age of patients was 59, with 49% being male. The most common underlying tumors were urothelial (45%), cervical (17%) and prostate cancer (15%). Clinical characteristics included ureteral stents (17%), diabetes (19%), history of GU surgery (38%), and active chemotherapy at the time of PCN insertion (70%). The median time to onset of infection was 42 days. Infections were polymicrobial in 50% of the cases. The most common organisms encountered were Pseudomonas spp. (36%), Enterococcus spp. (23%) and Escherichia coli (18%). The median length of follow up of PCN tubes after exchange was 55 days. There were 12 (26%) recurrences occurring at a median time of 27 days. The provision of discordant antibiotics preceding PCN exchange was significantly associated with recurrence of infection (66.7% vs. 12.8%; P < 0.002). Conclusion Discordant antimicrobial therapy provided during PCN exchange, in the setting of a PCN infection is associated with a higher rate of relapse. Therefore, to decrease the high rate for PCN reinfection, we propose that prior to PCN exchange secondary to infection, patients should be receiving concordant antimicrobial therapy. Disclosures All authors: No reported disclosures.


2013 ◽  
Vol 46 (5) ◽  
pp. 865-869 ◽  
Author(s):  
Marco Antonio Arap ◽  
Hiury Andrade ◽  
Fabio Cesar Miranda Torricelli ◽  
Francisco Tibor Denes ◽  
Anuar Ibrahim Mitre ◽  
...  

2020 ◽  
Vol 28 (3) ◽  
pp. 206-211
Author(s):  
Selahattin Kumru ◽  
Serdar Kaya

Objective: We aimed to present the procedure of intrauterine percutaneous fetoscopic laser valve ablation performed on a fetus diagnosed with lower urinary tract obstruction. Case(s): Bilateral hydroureteronephrosis, dilated bladder and oligo/ anhydramnios were found in the fetal ultrasonography examination of a 21-year-old pregnant woman who did not have regular follow-ups, and the lower urinary tract obstruction consistent with the posterior urethral valve was considered in the case. The patient who was found to have poor prognosis as a result of vesico synthesis carried out consecutively was informed about the follow-up and treatment options, and the posterior urethral valve ablation was performed by the percutaneous fetoscopic laser on 27 weeks of gestation. The amniotic fluid was at normal levels after the procedure, and the labor was carried out at term. The newborn with elevated postpartum creatinine was diagnosed with stage 2 renal failure, but dialysis was not required during the follow-ups. The newborn was discharged for outpatient follow-up upon the reduced creatinine levels. Conclusion: By taking the survival enhancing effect of the intrauterine intervention into account in the presence of lower urinary tract obstruction, we considered that intrauterine intervention can be an option in the cases who prefer to continue their pregnancies. The families should be informed in detail about the benefits and risks of intrauterine intervention to repair the obstruction.


Author(s):  
Rezkalla Akkary ◽  
Cyrus Chargari ◽  
Florent Guérin ◽  
Loic Jochault ◽  
Georges Audry ◽  
...  

Background: Outcome of children with bladder-prostate rhabdomyosarcoma has improved with multimodal therapies, including surgery and/or radiotherapy for local treatment. Our aim was to report the long-term urological complications after a conservative approach combining conservative surgery and brachytherapy. Patients and methods: Eighty-six patients, free of disease, were retrospectively reviewed. Symptoms related to urinary tract obstruction, incontinence, infection and lithiasis were reported and graded according to CTCAE classification. Only symptomatic patients underwent urodynamic studies. Risk factors for complications were analyzed. Results: There were 76 males and 10 females. The median follow-up was 6.3 years (18 months-24 years). Complications occurred after a median follow up 5 years (0-21). Twenty-two patients had long-term urological complications. Urinary tract obstruction was found in 15 patients, urinary incontinence in 14 patients. Recurrent urinary tract infection and urinary lithiasis were found in 5 patients respectively. Beyond symptom, 3 etiologies were identified: bladder dysfunction in 15 patients, urethral stenosis in 6 and uretero-vesical junction stenosis in 5. Posterior bladder wall dissection used in large prostatic tumors, operation at age less than 2 years and partial prostatectomy were identified as risk factors for these complications. Conclusion: The conservative surgical approach combined with brachytherapy for BPRMS leads to long-term urological complications in 22% of patients free of their disease. Optimizing brachytherapy doses for young children and establishing a clear and long term follow-up protocol, could help to reduce these complications.


2014 ◽  
Vol 2014 ◽  
pp. 1-3
Author(s):  
Dominik Abt ◽  
Gautier Müllhaupt ◽  
Livio Mordasini ◽  
Pierre André Diener ◽  
Hans-Peter Schmid

Primary adenocarcinoma of the upper urinary tract, particularly of the ureter, is an extremely rare entity. We are reporting on the first case of metachronous appearance in one patient. The 71-year-old man underwent partial ureterectomy (R0 resection) for primary adenocarcinoma of the left distal ureter. 3 years later, nephroureterectomy had to be performed because of metachronous primary adenocarcinoma of the left proximal ureter. Extensive examinations revealed no evidence for further malignancies at both times. Primary adenocarcinoma of the upper urinary tract is rare but should be kept in mind, especially in patients with chronic inflammation and urinary tract obstruction. Due to the low incidence, there is a lack of data regarding its pathogenesis, diagnosis, and optimal treatment.


PEDIATRICS ◽  
1961 ◽  
Vol 27 (1) ◽  
pp. 29-38
Author(s):  
Kurt Marx ◽  
W. Andrew Dale

A case of neonatal ascites associated with severe, obstructive uropathy is described. Recovery followed correction of the urinary tract obstruction. Follow-up data, including those pertaining to growth and development, over a 4-year period are presented. Attempts to demonstrate leakage of urine or a direct communication between the urinary tract and the peritoneal cavity were made, but failed. The pathogenesis of congenital ascites in infants with bilateral hydronephrosis and hydro-ureters remains obscure.


2021 ◽  
Vol 14 (3) ◽  
pp. 142-149
Author(s):  
A.A. Volkov ◽  
◽  
N.V. Budnik ◽  
O.N. Zuban ◽  
◽  
...  

Introduction. Currently, the basis for effective treatment of urinary tuberculosis (UT) is a combination of specific chemotherapy with reasonable surgical intervention and strict follow-up of the patient. Materials and methods. This literature review presents the evolution of methods of surgical treatment of renal and upper urinary tract tuberculosis over of 127 sources found for the review, 63 were selected. Results. Since UT is a very slowly progressive disease with minimal and imperceptible symptoms, often leading to irreversible organ damage, up to 75% of patients with this pathology undergo surgery. As follows from the results of recent studies, the emphasis of surgical treatment is increasingly shifting from ablative and organ-carrying techniques to reconstructive operations. Surgery for upper urinary tract tuberculosis continues to develop, but its results in advanced cases of destruction of renal tissue often remain unsatisfactory. Conclusions. The search for new methods of reconstructive interventions, the purpose of which is to preserve functioning renal-ureteral units and improve the quality of life of patients, remains relevant.


2020 ◽  
Vol 2020 (8) ◽  
Author(s):  
Mohsen Ezzy ◽  
Thomas Kraus ◽  
Stefan Berkhoff

Abstract Dysphagia secondary to osteoarticular disorders is a rare entity. In this report, we present the case of a 76-year-old female patient with progressive dysphagia and recurrent aspiration pneumonia caused by large anterior cervical osteophytes. Osteophytectomy was performed without spinal fusion. The patient reported significant improvement post-operatively, and no recurrence was detected at the 1-year follow-up. Cervical osteophytosis should be suspected as a cause of dysphagia, especially in elderly patients with degenerative osteoarthritic disease when other causes have been excluded.


2013 ◽  
Vol 7 (11-12) ◽  
pp. 708 ◽  
Author(s):  
Aihua Li ◽  
Sikuan Liu ◽  
Honghai Lu ◽  
Feng Zhang ◽  
Jun Lu ◽  
...  

Objective: We explore the clinical character of cystitis glandularis accompanied with upper urinary tract obstruction.Methods: We compared 70 cases of cystitis glandularis accompanied with upper urinary tract obstruction with 60 cases of cystitis glandularis without upper urinary tract obstruction. The difference of clinical manifestation and surgical efficacy was observed between the 2 groups.Results: The incidence of cystitis glandularis in women was higher than in men and the age of patients with cystitis glandularis and upper urinary tract obstruction was younger than the age of patients without upper urinary tract obstruction. The main symptom of cystitis glandularis accompanied with upper urinary tract obstruction were renal colic and abdominal pain; a few patients with a shorter course of the disease also had nausea, vomiting, frequency, urgency, dysuria, hematuria and fever. The distribution and morphological characteristics of lesions on the bladder and in the urine culture were not different between the 2 groups. There was no second operation on patients with upper urinary tract obstruction, but at least a second operation was performed on 9.3% patients without upper urinary tract obstruction.Conclusions: In patients with upper urinary tract obstruction, we found that it was the main clinical symptom of their cystitis glandularis. Identifying and removing the causes of upper urinary tract obstruction is the most important management method. For the cystitis glandularis, active treatment or close follow-up should be made.


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