scholarly journals Progressive Muscle Relaxation and Guided Imagery in Breast Cancer: A Systematic Review and Meta-analysis of Randomised Controlled Trials

2021 ◽  
Vol 27 ◽  
pp. 336-344
Author(s):  
Mithilesh Kumar Sinha ◽  
Apurba Barman ◽  
Manish Goyal ◽  
Suravi Patra
Keyword(s):  
Breast Cancer ◽  
Quality Of Life ◽  
Adverse Effects ◽  
Randomised Controlled Trials ◽  
Guided Imagery ◽  
Muscle Relaxation ◽  
Progressive Muscle Relaxation ◽  
Controlled Trials ◽  
Randomised Controlled

Breast cancer affects the mental well-being of patients who may need psychological support. The combined practice of progressive muscle relaxation (PMR) and guided imagery (GI) is known to improve psychological health. Its effect has been studied in patients with breast cancer. We need to systematically review and analyse the available data to outline its role in various stages of disease management. We wanted to evaluate the effect of the combined practice of PMR and GI on stress, anxiety, depression and mood. We also wanted to study the impact on quality of life and chemotherapy-related adverse effects. A systematic search and evaluation of the literature was performed. Five randomised controlled trials were selected for data extraction and construction of forest plots. The intervention was effective for stress and anxiety. It positively improved the quality of life but saw no significant improvement in chemotherapy-related adverse effects.

scholarly journals Systematic Review with Meta-Analysis: Effectiveness and Safety of Acupuncture as Adjuvant Therapy for Side Effects Management in Drug Therapy-Receiving Breast Cancer Patients

2021 ◽  
Vol 2021 ◽  
pp. 1-15
Author(s):  
Yau-Tuen Chan ◽  
Ning Wang ◽  
Chi-Wing Tam ◽  
Hor-Yue Tan ◽  
Yuanjun Lu ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Quality Of Life ◽  
Side Effects ◽  
Randomised Controlled Trials ◽  
Primary Outcome ◽  
Meta Analysis ◽  
Controlled Trials ◽  
Real Acupuncture ◽  
Randomised Controlled

Objective. To investigate the potential benefits and safety of acupuncture on managing side effects induced by drug therapies in patients with breast cancer using a PRISMA standard systematic review and meta-analysis. Methods. Published randomised controlled trials from nine databases in English and Chinese language were searched. Trials with a real acupuncture treatment group and a control group with sham acupuncture, no treatment, or waitlist control were included. The primary outcome of this study was the therapeutic effects on five symptoms induced by drug therapies, including gastrointestinal disorder, neuropathy, arthralgia, joint symptoms, and cognitive impairment. The quality of life was assessed as a secondary outcome. The risk of bias of each study was analysed according to the Cochrane Handbook. Results. Sixteen randomised controlled trials with 1189 participants were included in the meta-analysis. The primary outcome and all subgroup analyses showed statistically significant improvements in the management of side effects by real acupuncture. The quality of life of patients has enhanced during the treatment. Conclusion. Although the number of publications is limited, a clear preliminary conclusion could be drawn by the meta-analysis, suggesting the beneficial adjuvant role of acupuncture in patients with breast cancer who receive drug therapies. No serious adverse events were observed from all the RCTs, and the safety of acupuncture is ascertained. More standardised and sophisticated large-scale randomised controlled trials are needed to evaluate the findings further.

scholarly journals Endocrinology trial design: adverse event reporting in randomised controlled trials of recombinant human GH in GH-deficient adults

2002 ◽  
Vol 175 (2) ◽  
pp. 545-552 ◽  
Author(s):  
J Bryant ◽  
E Loveman ◽  
C Cave ◽  
D Chase ◽  
R Milne
Keyword(s):  
Quality Of Life ◽  
Adverse Event ◽  
Adverse Effects ◽  
Adverse Events ◽  
Randomised Controlled Trials ◽  
Controlled Trials ◽  
Number Of Patients ◽  
Randomised Controlled ◽  
The Impact

We have evaluated the reporting of withdrawals due to adverse effects and specific adverse effects in randomised controlled trials of recombinant human GH in adults. A systematic review was carried out of randomised controlled trials of the clinical effectiveness of recombinant human GH in adults with GH deficiency in relation to impact on quality of life. Trials were identified from searching electronic databases, bibliographies of related articles and consulting experts. There was reporting of withdrawals due to adverse effects and specific adverse effects. Rates of oedema and arthralgia were reported in included trials. Seventeen randomised controlled trials, published between 1990 and 1999, met the inclusion criteria for the review. Nine trials reported data on the effectiveness of GH on quality of life in adults. Only five trials (29%) reported both withdrawals from the study because of adverse events and specific adverse events with numbers per study arm and per type. Six further trials (35%) reported either withdrawal details or specific adverse event details or partial data on specific adverse events. Six trials (35%), however, did not report information on either withdrawals or specific adverse events. Ten of the 17 studies (59%) reported the number of patients who withdrew from the study due to adverse events per study arm and type of adverse event per study arm. Seven of the 17 trials (41%) reported the number of specific adverse events per study arm and six (35%) reported the type per study arm. The reporting of adverse events in randomised controlled trials of GH is variable and not consistent across trials. It is not possible to assess the impact that adverse events may have had on unblinding patients, and therefore the extent to which the effects of GH may have been overestimated. Therefore those conducting endocrinology trials in the future need to pay attention to the reporting of withdrawals due to adverse events and specific adverse events.

scholarly journals Reporting on Quality of Life in Randomised Controlled Trials in Gastrointestinal Surgery

2009 ◽  
Vol 14 (1) ◽  
pp. 156-165 ◽  
Author(s):  
Valerie Bridoux ◽  
Grégoire Moutel ◽  
Benoit Lefebure ◽  
Michel Scotte ◽  
Francis Michot ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Randomised Controlled Trials ◽  
Gastrointestinal Surgery ◽  
Controlled Trials ◽  
Randomised Controlled

A systematic review of randomised controlled trials of psychosocial interventions for acute mental health inpatients

2021 ◽  
Vol 10 (3) ◽  
pp. 1-17
Author(s):  
Laura D Wainwright ◽  
Gillian Haddock ◽  
Charlotte Dunster-Page ◽  
Katherine Berry
Keyword(s):  
Quality Of Life ◽  
Methodological Quality ◽  
Randomised Controlled Trials ◽  
Social Care ◽  
Psychosocial Interventions ◽  
Controlled Trials ◽  
Patient Functioning ◽  
Electronic Search ◽  
Randomised Controlled

Background/Aims Inpatient wards provide an opportunity to intervene with medical, psychological and social care to contain distress and prevent future relapse. However, they have been criticised for an over-reliance on medication and risk management with limited psychosocial interventions. The aim of this study was to investigate clinical trials of psychosocial interventions for inpatients to identify interventions that are effective at improving quality of life, symptoms or patient functioning. Methods An electronic search of six databases was conducted for papers published from 1806 up until February 2017. A total of 18 randomised controlled trials was identified in which outcomes for symptoms, quality of life or functioning were reported. Results Overall, 15 trials showed a statistically significant result for at least one outcome. Seven categories were identified from the 18 studies, at least one in each category was found to be effective for symptoms, quality of life or functioning. The majority were effective (15 out of 18). Conclusions Given that the methodological quality was generally low and number of randomised controlled trials were small, it is difficult to draw definitive conclusions. Recommendations include more and repeated trials using rigorous methods of testing and reporting.

scholarly journals Manfaat Progressive Muscle Relaxation (PMR) sebagai intervensi keperawatan dalam meningkatkan Quality of Life (QOL) wanita kanker payudara yang menjalani kemoterapi

2019 ◽  
Vol 2 (1) ◽  
Author(s):  
Anastasia Diah Larasati ◽  
Anggorowati Anggorowati ◽  
Andrew Johan
Keyword(s):  
Breast Cancer ◽  
Quality Of Life ◽  
Stress Reduction ◽  
Muscle Relaxation ◽  
Epidemiological Data ◽  
Review Literature ◽  
Progressive Muscle Relaxation ◽  
Literature Study ◽  
Patient Will

Based on epidemiological data, the incidence recorded globally by theInternational Agency for Research On Cancer (IARC) in 2012, as many as 43.3women had breast cancer. The patient will undergoing chemotherapy andexperience various disturbing symptoms. Various complaints can affect QOL.One of the therapies recommended by the journal Oncology Nursing is thetherapy of Progressive Muscle Relaxation (PMR).Objective: To find out the benefits of PMR as one of the nursing interventions indealing with the quality of life for women Ca. Mammae is undergoingchemotherapyThe method used in this paper is a review literature study. Databases used insource search are CINAHL, PubMed, Science Direct, and Medline. The criterionof inclusion in literature search is the year of article publishing starting in 2010until 2018, and the English full article. Search keywords are Progressive MuscleRelaxation, breast cancer, quality of life and chemotherapy. Literature analysisuses PICOT (Population, Intervention, Comparison, Outcome, and Time).Based on the analysis found 5 themes, namely the quality of life characteristicsof patients undergoing chemotherapy, PMR as a relaxation therapy, PMR as apsychological stress reduction intervention, PMR as an intervention to increasemuscle metabolism, and PMR as a pain reduction intervention.Patients who undergoing chemotherapy will experience a decrease in QOL. PMRis a recommended intervention to improve patient QOL.

scholarly journals The role of animal-assisted therapy in the management of people with dementia: a systematic literature review

BJPsych Open ◽  
2021 ◽  
Vol 7 (S1) ◽  
pp. S276-S276
Author(s):  
Syed Nabeel Javaid
Keyword(s):  
Quality Of Life ◽  
Cognitive Impairment ◽  
Literature Review ◽  
Systematic Literature Review ◽  
Randomised Controlled Trials ◽  
Animal Assisted Therapy ◽  
Controlled Trials ◽  
People With Dementia ◽  
Randomised Controlled

AimsThe aim of this systematic literature review was to determine the evidence-based effectiveness of animal assisted interventions and to look at the factors that limit implementation of this intervention.BackgroundDementia is a major health issue worldwide impacting not only on the people diagnosed with dementia, but also on their families and caregivers, and the healthcare professionals. The symptoms of dementia include cognitive impairment that can range from mild to severe, and behavioural and psychological symptoms which have debilitating effects on functional capacity and quality of life. A number of non-pharmacological interventions are being developed to help people with dementia. Animal assisted therapy is one of those interventions that has demonstrated positive effects on various aspects of dementia (Filan and Llewellyn-Jones, 2006). However, there are limitations to its use and feasibility of animal assisted therapy programmes is unclear.MethodOnly randomised-controlled trials (RCTs) were to be included to evaluate high quality evidence. A systematic literature search was carried out to find using the PubMed and Cochrane databases and a search of the NICE website. Literature was screened according to inclusion and exclusion criteria. Eight randomised-controlled trials were selected to be used in this systematic review to assess the effectiveness of animal-assisted therapy.ResultThe results regarding the effectiveness of animal assisted therapy were variable. There was some improvement demonstrated in symptoms of depression, agitation, behaviour and cognitive impairment. Quality of life and activities of daily living also demonstrated positive outcomes. There was a reduction in the risk of falls in people with dementia. However, the studies conducted demonstrated limited methodologies. The factors limiting the use of animal assisted therapy were found to be concerns around adverse events to animals, issues of animal welfare and economic feasibility of animal assisted therapy programmes.ConclusionFurther research needs to be done using properly conducted randomised controlled trials with larger sample sizes to formally assess people's perceptions regarding therapy animals and develop clear guidelines and protocols for integrating these interventions in healthcare.

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