scholarly journals Serum levels of testosterone and dehydroepiandrosterone sulfate in females with acne and/or female pattern hair loss

2020 ◽  
Vol 0 ◽  
pp. 1-6
Author(s):  
Raman Balakrishna Venkatta ◽  
Sheena Ann Simon ◽  
K. Abdul Samad ◽  
Anuja Elizabeth George
Keyword(s):  
Hair Loss ◽  
Colorimetric Method ◽  
Rank Correlation ◽  
Serum Levels ◽  
Dehydroepiandrosterone Sulfate ◽  
Total Testosterone ◽  
Spearman Rank Correlation ◽  
Spearman Rank ◽  
Female Pattern Hair Loss ◽  
The Mean

Objectives: The objectives of this study are as follows: (1) To study the levels of testosterone and dehydroepiandrosterone sulfate (DHEAS) in females with acne and/or female pattern hair loss (FPHL) and (2) to study the correlation of the severity of acne and/or FPHL with serum levels of testosterone and DHEAS. Materials and Methods: A cross-sectional study was carried out in the department of dermatology and venereology, of a tertiary care institution over a period of 1 year among patients who presented with acne and/or FPHL. Acne was graded using Leeds revised acne grading system and FPHL with Ludwig scale. Competitive immunoenzymatic colorimetric method for quantitative determination of testosterone and DHEAS concentrations in serum (“DiaMetra” kits) was performed. Correlation between quantitative variables was assessed by Pearson correlation and Spearman rank correlation. Results: A total of 84 patients with acne and/FPHL were studied over a period of 1 year. Fifty-one (60.7%) patients had acne, 21 (25%) had FPHL, and 12 (14.3%) patients had both. The mean levels of testosterone in acne, FPHL, and in patients with both were 1.14 ± 4.65 ng/ml, 0.51 ± 0.17 ng/ml, and 0.53 ± 0.24 ng/ml, respectively. The mean DHEAS in patients with acne, FPHL, and with both was 4.64 ± 4.96 μg/ml, 4.96 ± 5.34 μg/ml, and 6.34 ± 5.37 μg/ml, respectively. The Spearman rank correlation between the level of testosterone and the grades of inflammatory acne in face and FPHL was 0.193 and -0.16, respectively. The Spearman rank correlation of DHEAS with the grades of inflammatory acne in face and FPHL was 0.092 and 0.01, respectively. Limitations: The study carried out in a tertiary referral center, not reflecting the status of the condition in general population was the major limitation. Conclusion: This study in a localized population could not elicit a significant statistical correlation between serum levels of total testosterone and DHEAS with severity of acne or FPHL. However, a majority of patients with acne, FPHL, or both had low levels of total testosterone which were discordant with most of the previous studies. Half of the study population with coexisting acne and FPHL had high levels of DHEAS which suggests the need to study the role of DHES in patients with coexistence of acne and FPHL.

scholarly journals Effect of Spectral CT on Tumor Microvascular Angiogenesis in Renal Cell Carcinoma

2021 ◽  
Author(s):  
Bei Zhang ◽  
Qiong Wu ◽  
Xiang Qiu ◽  
Xiaobo Ding ◽  
Jin Wang ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Tumor Angiogenesis ◽  
Renal Cell ◽  
Rank Correlation ◽  
Correlation Coefficients ◽  
Spectral Ct ◽  
Spearman Rank Correlation ◽  
Spearman Rank ◽  
The Mean

Abstract Background: To examine the value of spectral CT quantitative parameters in renal cell carcinoma (RCC) microvascular angiogenesis.Methods: The authors evaluated 32 patients with pathologically confirmed RCC who underwent triple-phase contrast-enhanced CT with spectral CT imaging mode from January 2017 to December 2019. Quantitative parameters including the parameters derived from iodine concentration (IC) and water concentration (WC) of 120 keV monochromatic images. The microvascular density (MVD), microvascular area (MVA) and etc. al. of specimens were evaluated. The correlation between IC and WC (including average values and random values) with microvascular parameters were analyzed using Pearson or Spearman rank correlation coefficients.Results: The MVD of all tumors was 26.00 (15.00-43.75) vessels per field at ×400 magnification. The MVD of RCC correlated positively with the mean IC, mean WC, mean NWC, mean NIC, random IC, random NIC in renal cortical phase, WCD1, WCD2, NWCD2 and ICD1 (Spearman rank correlation coefficients, r range, 0.362–0.533; all p < 0.05). The MVA of all tumors was (16.16±8.98) % per field at ×400 magnification. The MVA of RCC correlated positively with the mean IC, mean WC, mean NWC, mean NIC, random IC, random NIC in renal cortical, mean WC and mean NWC in renal parenchymal phase, WCD1, WCD2, WCD3, NWCD2, and NWCD3 (Pearson or Spearman rank correlation coefficients, r range, 0.357–0.576; all p < 0.05). Microvascular grading correlated positively with the mean NWC, mean NIC and random NIC in renal cortical phase, mean NWC in renal parenchymal phase, NWCD2, WCD3, NWCD3, NICD2 and NICD3 (Spearman rank correlation coefficients, r range, 0.367–0.520; all p < 0.05). As for tumor diameter (55.19±19.15), μm, only NWCD3 was associated with it (Spearman rank correlation coefficients, r = 0.388; p < 0.05). Conclusions: IC and WC indexes derived from spectral CT, especially the renal cortical phase, difference between renal cortical phase and parenchymal phase were useful indicators for evaluating tumor angiogenesis. Moreover, the difference of the derived parameters of WC in different phases has stronger correlation with tumor angiogenesis than that of IC.

scholarly journals Rola aktywności zewnętrznej w rozwoju krótkowzroczności u dzieci w wieku szkolnym

2017 ◽  
Vol 62 (4) ◽  
Author(s):  
Maciej Czepita ◽  
Leszek Kuprjanowicz ◽  
Krzysztof Safranow ◽  
Artur Mojsa ◽  
Ewa Majdanik ◽  
...  
Keyword(s):  
Rank Correlation ◽  
P Value ◽  
Spherical Equivalent ◽  
Outdoor Activity ◽  
Spearman Rank Correlation ◽  
Spearman Rank ◽  
Kolmogorov Smirnov ◽  
The Mean ◽  
Spearman Rank Correlation Coefficient ◽  
Smirnov Test

Introduction: The aim of our study was to examine whether outdoor activity influences the prevalence of myopia in schoolchildren.Materials and methods: 5601 Polish students of elementary and secondary schools (2688 boys and 2913 girls), 6–18 years of age (mean 11.9 ±3.2 years) were examined. In every student cycloplegia after 1% tropicamide was performed. The mean spherical equivalent (SE) was calculated after examination of both eyes. Time spent on outdoor activity was evaluated based on a questionnaire. The obtained results were typed into an Excel spreadsheet and analyzed statistically using Statistica 10 software. Non-parametric tests were used due to the SE distribution being significantly different from normal distribution in the Kolmogorov–Smirnov test. The Spearman rank correlation coefficient (Rs) was used to evaluate the strength of the correlation between these variables. A p-value less than 0.05 was considered significant.Results: It has been established that with the increase in time spent on outdoor activity, the spherical equivalent of the examined students significantly increases, but the correlation is very weak (Rs = +0.036, p = 0.007).Conclusion: Outdoor activity slightly reduces the prevalence of myopia in schoolchildren.

scholarly journals Effect of spectral CT on tumor microvascular angiogenesis in renal cell carcinoma

BMC Cancer ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Bei Zhang ◽  
Qiong Wu ◽  
Xiang Qiu ◽  
Xiaobo Ding ◽  
Jin Wang ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Rank Correlation ◽  
Correlation Coefficients ◽  
Spectral Ct ◽  
Spearman Rank Correlation ◽  
Spearman Rank ◽  
Quantitative Parameters ◽  
The Mean

Abstract Background To examine the value of energetic-spectrum computed tomography (spectral CT) quantitative parameters in renal cell carcinoma (RCC) microvascular angiogenesis. Methods The authors evaluated 32 patients with pathologically confirmed RCC who underwent triple-phase contrast-enhanced CT with spectral CT imaging mode from January 2017 to December 2019. Quantitative parameters include parameters derived from iodine concentration (IC) and water concentration (WC) of 120 keV monochromatic images. All specimens were evaluated including the microvascular density (MVD), microvascular area (MVA) and so on. The correlation between IC and WC (including average values and random values) with microvascular parameters were analyzed with Pearson or Spearman rank correlation coefficients. Results The MVD of all tumors was 26.00 (15.00–43.75) vessels per field at × 400 magnification. The MVD of RCC correlated positively with the mean IC, mean WC, mean NWC, mean NIC, random IC, random NIC in renal cortical phase, WCD1, WCD2, NWCD2 and ICD1 (Spearman rank correlation coefficients, r range, 0.362–0.533; all p < 0.05). The MVA of all tumors was (16.16 ± 8.98) % per field at × 400 magnification. The MVA of RCC correlated positively with the mean IC, mean WC, mean NWC, mean NIC, random IC, random NIC in renal cortical, mean WC and mean NWC in renal parenchymal phase, WCD1, WCD2, WCD3, NWCD2, and NWCD3 (Pearson or Spearman rank correlation coefficients, r range, 0.357–0.576; all p < 0.05). Microvascular grading correlated positively with the mean NWC, mean NIC and random NIC in renal cortical phase, mean NWC in renal parenchymal phase, NWCD2, WCD3, NWCD3, NICD2 and NICD3 (Spearman rank correlation coefficients, r range, 0.367–0.520; all p < 0.05). As for tumor diameter (55.19 ± 19.15), μm, only NWCD3 was associated with it (Spearman rank correlation coefficients, r = 0.388; p < 0.05). Conclusions ICD and WCD of spectral CT have a potential for evaluating RCC microvascular angiogenesis. MVD, MVA and microvascular grade showed moderate positive correlation with ICD and WCD. ICD displayed more relevant than that of WCD. The parameters of renal cortical phase were the best in three phases. NICD and NWCD manifested stronger correlation with microvascular parameters than that of ICD and WCD.

HUBUNGAN BEBAN KERJA PERAWAT DENGAN KELENGKAPAN PENGISIAN DOKUMENTASI ASUHAN KEPERAWATAN

2020 ◽  
Vol 5 (2) ◽  
pp. 588
Author(s):  
Etlida Wati ◽  
Ulva Arini
Keyword(s):  
Nursing Care ◽  
Rank Correlation ◽  
Bivariate Analysis ◽  
Spearman Rank Correlation ◽  
Cross Sectional ◽  
Weight Category ◽  
Spearman Rank ◽  
Hospital Room ◽  
Analysis Technique ◽  
Nurse Workload

<p>Documentation is an activity of recording, reporting or recording an event and activities carried out in the form of providing services that are considered important and valuable. One factor that can influence documentation is the nurse's workload. The purpose of this study is to identify the relationship between nurses' workload and the application of documentation in the Hj. Anna Lasmanah Banjarnegara. This  research is quantitative with a cross sectional approach descriptive correlation design. Samples were taken with a total sampling of 65 nurses. Instruments to measure documentation using observation sheets. While the nurse workload instrument uses a questionnaire sheet. The analysis technique uses Spearman Rank correlation. Based on the research results of the workload of a nurse in the hospital room , most of them are in the weight category, as many as 46 respondents (70.8%). Application of nursing care documentation in the hospital room Hj. Anna Lasmanah Banjarnegara, most of them are respondents in the incomplete category as many as 63 respondents (96.9%). There is a significant relationship between nurse workload with the application of documentation, this is evidenced by the results of the Spearman Rank correlation bivariate analysis, which is r = 0.688 with p = 0.000 &lt;0.05. It is hoped that management will motivate nurses to complete the documentation of nursing care</p>

scholarly journals Does continuity in nursing staff matter? A pilot study on correlation of central line-associated bloodstream infections and employee turnover

2021 ◽  
Vol 10 (1) ◽  
Author(s):  
Thomas Scheier ◽  
Stefan P. Kuster ◽  
Mesida Dunic ◽  
Christian Falk ◽  
Hugo Sax ◽  
...  
Keyword(s):  
Nursing Staff ◽  
Employee Turnover ◽  
Rank Correlation ◽  
Bloodstream Infections ◽  
Central Line ◽  
Incidence Rates ◽  
Nursing Personnel ◽  
Care Hospital ◽  
Spearman Rank Correlation ◽  
Spearman Rank

Abstract Background Understaffing has been previously reported as a risk factor for central line-associated bloodstream infections (CLABSI). No previous study addressed the question whether fluctuations in staffing have an impact on CLABSI incidence. We analyzed prospectively collected CLABSI surveillance data and data on employee turnover of health care workers (HCW) to address this research question. Methods In January 2016, a semiautomatic surveillance system for CLABSI was implemented at the University Hospital Zurich, a 940 bed tertiary care hospital in Switzerland. Monthly incidence rates (CLABSI/1000 catheter days) were calculated and correlations with human resources management-derived data on employee turnover of HCWs (defined as number of leaving HCWs per month divided by the number of employed HCWs) investigated. Results Over a period of 24 months, we detected on the hospital level a positive correlation of CLABSI incidence rates and turnover of nursing personnel (Spearman rank correlation, r = 0.467, P = 0.022). In more detailed analyses on the professional training of nursing personnel, a correlation of CLABSI incidence rates and licensed practical nurses (Spearman rank correlation, r = 0.26, P = 0.038) or registered nurses (r = 0.471, P = 0.021) was found. Physician turnover did not correlate with CLABSI incidence (Spearman rank correlation, r =  −0.058, P = 0.787). Conclusions Prospectively determined CLABSI incidence correlated positively with the degree of turnover of nurses overall and nurses with advanced training, but not with the turnover of physicians. Efforts to maintain continuity in nursing staff might be helpful for sustained reduction in CLABSI rates.

scholarly journals In vivo calibration of the T2* cardiovascular magnetic resonance method at 1.5 T for estimation of cardiac iron in a minipig model of transfusional iron overload

2021 ◽  
Vol 23 (1) ◽  
Author(s):  
Peter Diedrich Jensen ◽  
Asbjørn Haaning Nielsen ◽  
Carsten Wiberg Simonsen ◽  
Ulrik Thorngren Baandrup ◽  
Svend Eggert Jensen ◽  
...  
Keyword(s):  
Rank Correlation ◽  
Calibration Data ◽  
Iron Loading ◽  
Spearman Rank Correlation ◽  
Calibration Equation ◽  
Spearman Rank ◽  
Cardiac Iron ◽  
In Vivo Calibration ◽  
Spearman Rank Correlation Coefficient

Abstract Background Non-invasive estimation of the cardiac iron concentration (CIC) by T2* cardiovascular magnetic resonance (CMR) has been validated repeatedly and is in widespread clinical use. However, calibration data are limited, and mostly from post-mortem studies. In the present study, we performed an in vivo calibration in a dextran-iron loaded minipig model. Methods R2* (= 1/T2*) was assessed in vivo by 1.5 T CMR in the cardiac septum. Chemical CIC was assessed by inductively coupled plasma-optical emission spectroscopy in endomyocardial catheter biopsies (EMBs) from cardiac septum taken during follow up of 11 minipigs on dextran-iron loading, and also in full-wall biopsies from cardiac septum, taken post-mortem in another 16  minipigs, after completed iron loading. Results A strong correlation could be demonstrated between chemical CIC in 55 EMBs and parallel cardiac T2* (Spearman rank correlation coefficient 0.72, P < 0.001). Regression analysis led to [CIC] = (R2* − 17.16)/41.12 for the calibration equation with CIC in mg/g dry weight and R2* in Hz. An even stronger correlation was found, when chemical CIC was measured by full-wall biopsies from cardiac septum, taken immediately after euthanasia, in connection with the last CMR session after finished iron loading (Spearman rank correlation coefficient 0.95 (P < 0.001). Regression analysis led to the calibration equation [CIC] = (R2* − 17.2)/31.8. Conclusions Calibration of cardiac T2* by EMBs is possible in the minipig model but is less accurate than by full-wall biopsies. Likely explanations are sampling error, variable content of non-iron containing tissue and smaller biopsies, when using catheter biopsies. The results further validate the CMR T2* technique for estimation of cardiac iron in conditions with iron overload and add to the limited calibration data published earlier.

scholarly journals Interactional Justice and Employees’ Commitment to Supervisor in Nigerian Health Sector

2015 ◽  
Vol 2 (5) ◽  
pp. 7-17 ◽  
Author(s):  
Ajogwu Akoh ◽  
Edwinah Amah
Keyword(s):  
Health Sector ◽  
Rank Correlation ◽  
Interactional Justice ◽  
Survey Questionnaire ◽  
Spearman Rank Correlation ◽  
Interpersonal Justice ◽  
Informational Justice ◽  
Spearman Rank ◽  
The Relationship ◽  
Spearman Rank Correlation Coefficient

This research was designed to study the relationship between interactional justice and employees’ commitment to supervisor in Nigerian health sector. A self-administered survey questionnaire was sent out to a sample size of 103 employees, resulting in 99 responses out of which 13 copies of the questionnaire were not statistically usable. The Spearman rank correlation coefficient was used for data analysis, and our findings reveal that employees who have received fair informational and interpersonal treatments commit themselves to their supervisors. We discovered that the degree of influence exerted by interpersonal justice on employees’ commitment to supervisor was stronger than that of informational justice. We concluded that employees attach themselves to supervisors that are fair in communication and relationship. The fairness of interaction and communication boost employees’ confidence, impacting positively on employees’ commitment to supervisor and making employees see themselves as part owners in the organization. We, therefore, recommended that organizational managers or supervisors should communicate and relate properly with employees, in order to satisfy their customers and other stakeholders.

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