scholarly journals Systemic toxicity in a child after topical cyclopentolate eye drops application

2021 ◽  
Vol 36 ◽  
pp. 138-139
Author(s):  
Abhinay Ashok ◽  
Y. Manoj Bhat
Keyword(s):  
Blood Pressure ◽  
Oxygen Saturation ◽  
Pulse Rate ◽  
Visual Hallucination ◽  
Systemic Toxicity ◽  
Eye Drops ◽  
Mild Pain

An 8-year-old girl was seen in our ophthalmology OPD who had come with complaints of mild pain in both eyes for 1 month. Her unaided vision in both eyes was 6/6. Her weight was 20 kg. Cyclopentolate 1% eye drops was administered twice to the child at 5 min interval in both eyes. The child became restless after 30 min of installation of eye drops installation. She started behaving abnormally and was not allowing to do retinoscopic examination. She had altered behavior, visual hallucination, and difficulty in walking. She was disoriented with slurred speech. She had ataxia and frequent tightening of limbs with jerky movements and was plucking her hair. Her pulse rate was 90/min and blood pressure was 120/90 mm of Hg. Her oxygen saturation was 94% in room air. The child was shifted to nearby hospital where a paediatrician and anesthesiologist were available and was kept under observation. Child’s pulse, blood pressure, and oxygen saturation were monitored for the next 5 hours. The child recovered completely over the next 8 hours.

scholarly journals Effect of Local Anaesthesia with and without Adrenaline on Blood Pressure, Pulse Rate and Oxygen Saturation - A Comparative Study

2020 ◽  
Vol 4 (1) ◽  
pp. 18-21
Author(s):  
Deepak Yadav ◽  
Harleen Bali ◽  
Ravish Mishra ◽  
Laxmi Kandel ◽  
Nitin Khanduri ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Oxygen Saturation ◽  
Pulse Rate ◽  
Local Anaesthesia ◽  
Work Performance ◽  
Pressure Pulse ◽  
Randomized Study ◽  
Significant Rise ◽  
Oral Surgical Procedures ◽  
Group 2

Introduction: Most of the minor oral surgical procedures are performed under local anaesthesia (LA). Vasoconstrictor present in LA decreases the rapid absorption of LA, decreases systemic toxicity, increases duration of LA and provides local hemostasis which favor clinicians for better work performance. But it is also known to increase heart rate (HR) and blood pressure (BP). Objective: To evaluate the effect of vasoconstrictor adrenaline 1:80,000 in 1.8 ml of 2% Lidocaine on systolic and diastolic blood pressure, pulse rate and oxygen saturation of normotensive patients. Methods: A prospective randomized study was conducted on 70 patients who were divided randomly into 2 parallel groups according to the LA received. Group 1 (G1): lidocaine 2% without adrenaline and Group 2 (G2): lidocaine 2% with adrenaline 1:80,000. Blood pressure, pulse rate and oxygen saturation were measured before and 10 minutes after LA administration for each patient. Results: Statistically significant rise in blood pressure and pulse rate was seen in group receiving LA with adrenaline (G2) 10 minutes after administration. Conclusion: Though adrenaline amount in 1.8ml causes significant rise of parameters assessed under the study, the rise is not clinically relevant for a normotensive, medically fit patient.

scholarly journals PHYSIOLOGICAL CHANGES DURING VAMAN PROCEDURE

2021 ◽  
Vol 9 (7) ◽  
pp. 1328-1333
Author(s):  
Sumeet Saini ◽  
Muralidhar P Pujar ◽  
Ashvini Kumar M ◽  
Lohith B A
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Oxygen Saturation ◽  
Healthy Volunteers ◽  
Pulse Rate ◽  
Physiological Changes ◽  
Safety Aspects

Introduction: Vaman karma (therapeutic emesis) is one of the five Shodhan (purificatory) procedures mentioned in Ayurveda. It helps to expel vitiated Doshas from Urdhvabhaga i.e. mouth. A person performing Vaman regularly has very less chances of suffering from any disease. It is used as both a preventive and curative measure in healthy and diseased persons, respectively. So here in this study efforts have been made to observe the physiological changes occurring in various parameters like Pulse rate, Blood Pressure, Temperature, and oxygen saturation at different intervals, before the onset of Vega, just after 3-4 sec of completion of Vega, and during the whole of the Vaman procedure to understand the safety aspects of the procedure in patients and healthy volunteers. Methods: 20 subjects were selected irrespective of gender and religion from IPD of the Department of Panchakarma; they are first prepared with Deepan-Pachan followed by Snehan and Swedan before Vaman karma. Results: on keen ob- servation, it was found that there is a lot of variation in heart rate and sudden fluctuation in blood pressure at the time of vega during Vaman procedure. Conclusion: Vaman karma can be performed safely by anyone with proper assessment and examination of the patient without any complication. Keywords: Vaman, Panchakarma, physiological changes

scholarly journals Dexmedetomidine Enhances the Pulpal Anesthetic Effect of Lidocaine: A Pilot Study

2018 ◽  
Vol 65 (1) ◽  
pp. 38-43
Author(s):  
Yoko Tonooka ◽  
Katsuhisa Sunada
Keyword(s):  
Blood Pressure ◽  
Oral Cavity ◽  
Oxygen Saturation ◽  
Local Anesthesia ◽  
Pulse Rate ◽  
Bispectral Index ◽  
Root Apex ◽  
Time Points ◽  
Anesthetic Effect ◽  
Pulpal Anesthesia

Dexmedetomidine hydrochloride (DEX) demonstrates analgesic, sedative, and hypotensive effects. DEX may also enhance the effect of local anesthetics used in the oral cavity, although this has not been well established in combination with lidocaine. We conducted a single-blind crossover study in 8 healthy volunteers to investigate whether DEX enhances the anesthetic effect of lidocaine in the oral cavity. DEX or DEX + lidocaine was injected into the labial gingiva corresponding to the root apex of the maxillary left central incisor and into the buccal gingiva corresponding to the root apex of the mandibular right first molar. Pain threshold, blood pressure, pulse rate, oxygen saturation, and bispectral index were measured 5 minutes after treatment and at 10-minute intervals for 60 minutes. DEX + lidocaine caused pulpal anesthesia in more subjects than lidocaine alone; this difference was significant for both central incisors and first molars up to 40 minutes after treatment. Following DEX + lidocaine treatment, blood pressure and bispectral index were significantly reduced at several time points, and pulse rate significantly reduced at all time points. Neither treatment caused changes in oxygen saturation. In conclusion, administering DEX with lidocaine for dental local anesthesia caused sedation and enhanced local anesthesia compared to lidocaine alone.

The Effects of Passive and Active Smoking on Brachial and radial Blood Pressure and Some Other Physical Factors in Healthy Young Adults

2017 ◽  
Vol 5 (3) ◽  
pp. 259
Author(s):  
Shireen H. Ramadhan ◽  
Shamil K. Talal ◽  
Wasfiya A. Moner
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Oxygen Saturation ◽  
Oxygen Concentration ◽  
Tobacco Smoke ◽  
Blood Pressure Measurement ◽  
Reference Level ◽  
Physical Factors ◽  
New Device ◽  
Active Smoker

Tobacco smoke is enormously harmful to human health, there’s no safe way to smoke. The primary objective of this study is to analyze the role of tobacco smoke compounds and their ability to damage the cardiovascular system and, in particular, to interfere with blood pressure (Brachial and radial pressure), heart rate and partly on the percentage blood Oxygen saturation. A new device has been manufactured which is unique for measuring the level of smoke, to obtained privies readings, the device had fixed to the first reference level آ and starting up from it. The effect of smoking has been studied on (26) male passive (26) active smoker volunteer, (14) female passive and (14) female active smoker participants. The results has been showed that the blood pressure and heart rate has been increased with increasing the number of cigarettes in both genders for passive and active smokers. However, this effect for male was more pronounced comparing with females for passive and active smokers. In the case of oxygen saturation concentration percentage, for males the change of oxygen concentration percentage was not stable. In other words, it was fluctuated with the number of cigarettes. But for females the oxygen concentration was decreased but not too much. This means that this effect was not pronounced. this study found آ that the most pronounced effect has been shown by male’s comparison to females for both passive and active smokers. As well as in nonsmoker’s males, the relation between heart rate and smoke level is inversely proportional. While in male and female smokers and female nonsmokers the relation is proportional. In all cases the relation between the smoke level and time of smoking is inversely proportional. Finally males& females are affected differently by tobacco use; the sensitivities to smoke for males are higher than in females for passive and active smokers in both brachial and radial blood pressure measurement.

Anatomical and Morphological study of the Heart's Chambers and valves in Iraqi ducks Anser platyrhuncha

2019 ◽  
Vol 43 (1) ◽  
pp. 21-25
Author(s):  
Mohammed Senna Hassan
Keyword(s):  
Blood Pressure ◽  
Anterior Chamber ◽  
High Blood Pressure ◽  
Pulse Rate ◽  
Morphological Study ◽  
Heart Valves ◽  
Simple Manner ◽  
High Pulse ◽  
The Right ◽  
High Pulse Rate

   Twenty Iraqi ducks hearts ( 10 male and 10 female ) have been  used for   demonstration  and illustration of heart's valves  and chambers  as well as  anatomical   and morphological site of view to explain what modifications had been take place for ducks heart  to perform  his normal life at the  circumstances  of  high  blood  pressure  and  pulse  rate. The heart  which has distinctly pointed  apex  was  built   in simple  manner located  in a transparent  taught  heart  pericardial  sac. It   was pyramidal in shape  externally  and  has a longitudinal  salcus  passing  to the  right  side, the  anterior of  the   heart  is  divided  into two  unequal  anterior  chamber  similar  to  those of mammalian  hear  .The heart valves are modified  in  order to  minimize  the  fraction  that occur as a result of  high  blood  pressure  and  pulse  rate  of  the  duck  heart , also  the  muscular  trabeculae   replace  the  chordate  tendineae  , which  were  present in the  mammalian    heart  in order to  minimize  the  fraction  resulting  from high  pulse  rate..    

scholarly journals Differential effects of the blood pressure state on pulse rate variability and heart rate variability in critically ill patients

2021 ◽  
Vol 4 (1) ◽  
Author(s):  
Elisa Mejía-Mejía ◽  
James M. May ◽  
Mohamed Elgendi ◽  
Panayiotis A. Kyriacou
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Heart Rate Variability ◽  
Pulse Rate ◽  
Pulse Transit Time ◽  
Pulse Rate Variability ◽  
Physiological Factors ◽  
Ecg Signals ◽  
Non Invasive ◽  
Electrocardiogram Ecg

AbstractHeart rate variability (HRV) utilizes the electrocardiogram (ECG) and has been widely studied as a non-invasive indicator of cardiac autonomic activity. Pulse rate variability (PRV) utilizes photoplethysmography (PPG) and recently has been used as a surrogate for HRV. Several studies have found that PRV is not entirely valid as an estimation of HRV and that several physiological factors, including the pulse transit time (PTT) and blood pressure (BP) changes, may affect PRV differently than HRV. This study aimed to assess the relationship between PRV and HRV under different BP states: hypotension, normotension, and hypertension. Using the MIMIC III database, 5 min segments of PPG and ECG signals were used to extract PRV and HRV, respectively. Several time-domain, frequency-domain, and nonlinear indices were obtained from these signals. Bland–Altman analysis, correlation analysis, and Friedman rank sum tests were used to compare HRV and PRV in each state, and PRV and HRV indices were compared among BP states using Kruskal–Wallis tests. The findings indicated that there were differences between PRV and HRV, especially in short-term and nonlinear indices, and although PRV and HRV were altered in a similar manner when there was a change in BP, PRV seemed to be more sensitive to these changes.

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