scholarly journals Overview of the modeling of complex biological systems and its role in neurosurgery

2021 ◽  
Vol 12 ◽  
pp. 433
Author(s):  
Zaid Aljuboori
Keyword(s):  
Nervous System ◽  
Complex Systems ◽  
Biomedical Research ◽  
Systems Approach ◽  
Biological Systems ◽  
Self Organization ◽  
Human Biology ◽  
Linear Approach ◽  
Human Nervous System

Biological systems are complex with distinct characteristics such as nonlinearity, adaptability, and self-organization. Biomedical research has helped in advancing our understanding of certain components the human biology but failed to illustrate the behavior of the biological systems within. This failure can be attributed to the use of the linear approach, which reduces the system to its components then study each component in isolation. This approach assumes that the behavior of complex systems is the result of the sum of the function of its components. The complex systems approach requires the identification of the components of the system and their interactions with each other and with the environment. Within neurosurgery, this approach has the potential to advance our understanding of the human nervous system and its subsystems.

Non-stationary stationarity in systems of third type and philosophy of instability

2015 ◽  
Vol 4 (2) ◽  
pp. 65-74
Author(s):  
Гавриленко ◽  
T. Gavrilenko ◽  
Еськов ◽  
Valeriy Eskov ◽  
Еськов ◽  
...  
Keyword(s):  
Dynamical Systems ◽  
Complex Systems ◽  
Biological Systems ◽  
Deterministic Chaos ◽  
Stochastic Approach ◽  
Distribution Functions ◽  
Self Organization ◽  
Deterministic Approach ◽  
The Third ◽  
Specific Assessment

There are several criteria in science for stationarity (stability) of different dynamical systems. The stationarity in physics, engineering and chemistry is being interpreted as matching the requirements of dx/dt=0, where x=x(t) - is the vector of system’s state, or the equality of distribution functions f(x) for different samples which characterize the system. However, in case of social or biological systems the matching of the requirements is impossible and there is a problem of specific assessment of stationary regimes of complex systems of the third type. The possibility of studying of such systems within the frame of deterministic chaos, stochastic approach and theory of chaos and self-organization is being discussed. This article explains why I.R. Prigogine refused from materialistic (in fact deterministic) approach in the description of such special systems of third type and tried to get away from the traditional science in the description of biological systems.

Classification of Self-Organization and Emergence in Chemical and Biological Systems

2006 ◽  
Vol 59 (12) ◽  
pp. 849 ◽  
Author(s):  
Julianne D. Halley ◽  
David A. Winkler
Keyword(s):  
Complex Systems ◽  
Biological Systems ◽  
Self Organization ◽  
Systems Science ◽  
New Paradigm ◽  
Chemical And Biological Systems ◽  
Complex Systems Science

Most chemical and biological systems are complex, but the application of complex systems science to these fields is relatively new compared to the traditional reductionist approaches. Complexity can provide a new paradigm for understanding the behaviour of interesting chemical and biological systems, and new tools for studying, modelling, and simulating them. It is also likely that some very important, but very complicated systems may not be accessible by reductionist approaches. This paper provides a brief review of two important concepts in complexity, self-organization and emergence, and describes why they are relevant to chemical and biological systems

scholarly journals Aconitine Neurotoxicity According to Administration Methods

2021 ◽  
Vol 10 (10) ◽  
pp. 2149
Author(s):  
Ji Yeon Chung ◽  
Seung Jae Lee ◽  
Hyuck Jin Lee ◽  
Jeong Bin Bong ◽  
Chan-Hyuk Lee ◽  
...  
Keyword(s):  
Nervous System ◽  
Pain Control ◽  
Associated Factors ◽  
Clinical Characteristics ◽  
Processing Method ◽  
Neurological Symptoms ◽  
Administration Method ◽  
Accompanying Symptoms ◽  
Administration Methods ◽  
Human Nervous System

We evaluated the toxic effects of aconitine on the human nervous system and its associated factors, and the general clinical characteristics of patients who visited the emergency room due to aconitine intoxication between 2008 and 2017. We also analyzed the differences related to aconitine processing and administration methods (oral pill, boiled in water, and alcohol-soaked), and the clinical characteristics of consciousness deterioration and neurological symptoms. Of the 41 patients who visited the hospital due to aconitine intoxication, 23 (56.1%) were female, and most were older. Aconitine was mainly used for pain control (28 patients, 68.3%) and taken as oral pills (19 patients, 46%). The patients showed a single symptom or a combination of symptoms; neurological symptoms were the most common (21 patients). All patients who took aconitine after processing with alcohol showed neurological symptoms and a higher prevalence of consciousness deterioration. Neurological symptoms occurred most frequently in patients with aconitine intoxication. Although aconitine intoxication presents with various symptoms, its prognosis may vary with the processing method and prevalence of consciousness deterioration during the early stages. Therefore, the administration method and accompanying symptoms should be comprehensively investigated in patients who have taken aconitine to facilitate prompt and effective treatment and better prognoses.

scholarly journals Soil as an Archetype of Complexity: A Systems Approach to Improve Insights, Learning, and Management of Coupled Biogeochemical Processes and Environmental Externalities

Soil Systems ◽  
2021 ◽  
Vol 5 (3) ◽  
pp. 39
Author(s):  
Benjamin L. Turner
Keyword(s):  
Complex Systems ◽  
Systems Approach ◽  
Environmental Externalities ◽  
Supporting Evidence ◽  
Soil System ◽  
Tillage Practices ◽  
Trade Offs ◽  
Tightly Coupled ◽  
Conservation Adoption ◽  
Systems Framework

Due to tightly coupled physical, chemical, and biological processes that often behave in nonlinear, counterintuitive ways, it is argued that soil is an archetype of a complex system. Unfortunately, human intuition and decision making has been shown to be inadequate when dealing with complex systems. This poses significant challenges for managers or policy makers responding to environmental externalities where soil dynamics play a central role (e.g., biogeochemical cycles) and where full ranges of outcomes result from numerous feedback processes not easily captured by reductionist approaches. In order to improve interpretation of these soil feedbacks, a dynamic systems framework is outlined (capturing feedback often excluded from investigation or left to intuition) and then applied to agroecosystem management problems related to irrigation or tillage practices that drive nutrient cycling (e.g., soil water, nitrogen, carbon, and sodium). Key soil feedbacks are captured via a variety of previously developed models simulating soil processes and their interactions. Results indicated that soil system trade-offs arising from conservation adoption (drip irrigation or no-tillage) provided reasonable supporting evidence (via compensating feedbacks) to managers justifying slow adoption of conservation practices. Modeling soils on the foundation provided in the complex systems sciences remains an area for innovations useful for improving soil system management.

scholarly journals Extreme events defined—A conceptual discussion applying a complex systems approach

Futures ◽  
2020 ◽  
Vol 115 ◽  
pp. 102490 ◽  
Author(s):  
Lisa Hanna Broska ◽  
Witold-Roger Poganietz ◽  
Stefan Vögele
Keyword(s):  
Complex Systems ◽  
Extreme Events ◽  
Systems Approach ◽  
Conceptual Discussion

In-Between and Through: Architecture and Complexity

2005 ◽  
Vol 3 (3) ◽  
pp. 335-354 ◽  
Author(s):  
Clarissa Ribeiro Pereira de Almeida ◽  
Anja Pratschke ◽  
Renata La Rocca
Keyword(s):  
Complex System ◽  
Software Engineering ◽  
Complex Systems ◽  
Design Process ◽  
Three Dimensional ◽  
Self Organization ◽  
Three Dimensional Modeling ◽  
Dimensional Modeling ◽  
Complex Thought ◽  
Basic Characteristics

This paper draws on current research on complexity and design process in architecture and offers a proposal for how architects might bring complex thought to bear on the understanding of design process as a complex system, to understand architecture as a way of organizing events, and of organizing interaction. Our intention is to explore the hypothesis that the basic characteristics of complex systems – emergence, nonlinearity, self-organization, hologramaticity, and so forth – can function as effective tools for conceptualization that can usefully extend the understanding of the way architects think and act throughout the design process. To illustrate the discussions, we show how architects might bring complex thought inside a transdisciplinary design process by using models such as software engineering diagrams, and three-dimensional modeling network environments such as media to integrate, connect and ‘trans–act’.

An X-ray diffraction comparison of myelins from the human nervous system

1978 ◽  
Vol 177 (1) ◽  
pp. 1-9 ◽  
Author(s):  
Ronald J. Chandross ◽  
Richard S. Bear ◽  
Royce L. Montgomery
Keyword(s):  
Nervous System ◽  
X Ray Diffraction ◽  
X Ray ◽  
Human Nervous System
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