Living at the city center is associated with type-1 sensitization to pollen allergens in a random sample of the general population in Leipzig, Germany

2018 ◽  
Author(s):  
Regina Treudler
Keyword(s):  
General Population ◽  
Random Sample ◽  
City Center ◽  
Pollen Allergens ◽  
The City

scholarly journals Association of type 1 diabetes mellitus (DM1) with polymorphous alleles of HLA-DR and DQ genes in two Russian populations of Moscow and Vologda regions

2009 ◽  
Vol 12 (2) ◽  
pp. 28-32
Author(s):  
Tamara Leonidovna Kuraeva ◽  
M N Kashenin ◽  
M N Boldyreva, ◽  
N M Tsitlidze ◽  
A N Nikitin ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Type 1 Diabetes Mellitus ◽  
Random Sample ◽  
Local Population ◽  
New Associations ◽  
Hla Dr ◽  
Successive Generations ◽  
The City

Aim. To consider association of type 1 diabetes mellitus (DM1) with polymorphous alleles of HLA-DRB1 HLA-DQB1, and DQA1 genes in two Russian populations of Moscow (MP) and Vologda (VP) regions. Materials and methods. Identification of alleles of HLA-DRB1 HLA-DQB1, and DQA1 genes in 138 patients with type 1 diabetes and a random sample of 242 subjects from the local population (residents in at least three successive generations) of the Vologda region, 204 patients and a random sample of 300 subjects from the city of Moscow and Moscow region. Results. MP and VP exhibited identical predisposing alleles. The occurrence of DRB1*4 (RR=5.96 and 3.93 in MP and VP respectively), DRB1*17 (RR=4.33 and 4.23), DQA1*0301 (RR=5.70 and 3.66), DQB1*0201, (RR=2.06 and 1.77), DQB1* 0302 (RR=7.10 and 3.95), DQB1* 0304 (RR=8.94 and 19.98) alleles was significantly higher in DM1 patients. The following protective alleles were identified in MP and VP respectively: DRB1*7 (RR=0.37 and 0.18), DRB1*11 (RR=0.12 and 0.21), DRB1*13 (RR=0.09 and 0.26), DRB1*15 (RR=0.23 and 0.04), DQA1*0102 (RR=0.29 and 0.23), DQA1*0103 (RR=0.13 and 0.23), DQA1*0201 (RR=0.37 and 0.17), DQb1*0301 (RR=0.16 and 0.24), and DQB1*0602/8 (RR=0.10 and 0.13). Conclusion. ?New? associations unknown in other populations (e.g. DQB1*0304) were revealed, besides the majority of classical predisposing and protective alleles characteristic of European populations. DQB1*0304 proved the strongest predisposing allele in MP and especially in VP. These data suggest different contribution of predisposing alleles to the development of DM1 in individual populations.

Accuracy of On-site Consistent Origin-Destination Estimation Method for Measuring the Actual Numbers of Consumer Shop-around Movements within the City Center of Hanoi, Vietnam

2012 ◽  
Vol 42 (2) ◽  
pp. 439-455 ◽  
Author(s):  
Saburo SAITO ◽  
Tran Ngoc HUY ◽  
Masakuni IWAMI ◽  
Takahiro SATO ◽  
Kosuke YAMASHIRO ◽  
...  
Keyword(s):  
Estimation Method ◽  
City Center ◽  
The City

Urban Development Strategies of City Centers: The Case of Rafah City, Palestinian Territories

2014 ◽  
Vol 8 (3) ◽  
pp. 195
Author(s):  
Omar S. Asfour ◽  
Samar Abu Ghali
Keyword(s):  
Urban Development ◽  
Gaza Strip ◽  
Geographic Location ◽  
Development Strategies ◽  
Functional Requirements ◽  
City Center ◽  
Palestinian Territories ◽  
The Gaza Strip ◽  
The City ◽  
Commercial Center

City centers worldwide are perceived as essential parts of the city, where city memories are preserved and its identity is expressed. They are planned to satisfy the functional requirements and pleasurable qualities of the city. Under the accelerating urbanization of the modern city, several challenges face these centers including demographic, economic, and environmental challenges. This requires a continuous and incremental urban development process based on clear strategy and action plans. Thus, this study focuses on urban development strategies of city centers, with a focus on Rafah city located in the Gaza Strip, Palestinian Territories. The geographic location of this city near the Palestinian-Egyptian borders makes it a promising commercial city at local and regional levels. Thus, the current situation of Rafah city center has been analyzed, and several development strategies have been proposed. This has been done through a field survey based on observation and a questionnaire directed to city center users. It has been found that there is a great potential of Rafah city center to be developed as a commercial center. In this regard, several strategies and required actions have been proposed in the fields of transportation, environmental quality, shopping activities, investment opportunities, and visual perception.

Spatial and Temporal Differences in Weekday Travel Durations Between Private-for-Hire Transportation Services and Transit in the City Center

2021 ◽  
pp. 036119812110197
Author(s):  
Baxter Shandobil ◽  
Ty Lazarchik ◽  
Kelly Clifton
Keyword(s):  
Transportation Network ◽  
Central City ◽  
Temporal Analysis ◽  
Time Of Day ◽  
City Center ◽  
Transportation Services ◽  
Regulatory Frameworks ◽  
Transit Services ◽  
Level Information ◽  
The City

There is increasing evidence that ridehailing and other private-for-hire (PfH) services such as taxis and limousines are diverting trips from transit services. One question that arises is where and when PfH services are filling gaps in transit services and where they are competing with transit services that are publicly subsidized. Using weekday trip-level information for trips originating in or destined for the city center of Portland, OR from PfH transportation services (taxis, transportation network companies, limousines) and transit trip data collected from OpenTripPlanner, this study investigated the temporal and spatial differences in travel durations between actual PfH trips and comparable transit trips (the same origin–destination and time of day). This paper contributes to this question and to a growing body of research about the use of ridehailing and other on-demand services. Specifically, it provides a spatial and temporal analysis of the demand for PfH transportation using an actual census of trips for a given 2 week period. The comparison of trip durations of actual PfH trips to hypothetical transit trips for the same origin–destination pairs into or out of the central city gives insights for policy making around pricing and other regulatory frameworks that could be implemented in time and space.

scholarly journals Simulating the effects of redesigned street-scale built environments on access/egress pedestrian flows to metro stations

2021 ◽  
Vol 1 (1) ◽  
Author(s):  
Yanan Liu ◽  
Dujuan Yang ◽  
Harry J. P. Timmermans ◽  
Bauke de Vries
Keyword(s):  
Built Environment ◽  
Route Choice ◽  
Local Area ◽  
Destination Choice ◽  
Built Environments ◽  
Renewal Processes ◽  
City Center ◽  
Metro Station ◽  
Route Choice Behavior ◽  
The City

AbstractIn urban renewal processes, metro line systems are widely used to accommodate the massive traffic needs and stimulate the redevelopment of the local area. The route choice of pedestrians, emanating from or going to the metro stations, is influenced by the street-scale built environment. Many renewal processes involve the improvement of the street-level built environment and thus influence pedestrian flows. To assess the effects of urban design on pedestrian flows, this article presents the results of a simulation model of pedestrian route choice behavior around Yingkoudao metro station in the city center of Tianjin, China. Simulated pedestrian flows based on 4 scenarios of changes in street-scale built environment characteristics are compared. Results indicate that the main streets are disproportionally more affected than smaller streets. The promotion of an intensified land use mix does not lead to a high increase in the number of pedestrians who choose the involved route when traveling from/to the metro station, assuming fixed destination choice.

scholarly journals Selecting Freight Transportation Modes in Last-Mile Urban Distribution in Pamplona (Spain): An Option for Drone Delivery in Smart Cities

Energies ◽  
2021 ◽  
Vol 14 (16) ◽  
pp. 4748
Author(s):  
Adrian Serrano-Hernandez ◽  
Aitor Ballano ◽  
Javier Faulin
Keyword(s):  
Public Transportation ◽  
Smart Cities ◽  
Freight Transportation ◽  
City Center ◽  
Analytic Hierarchy ◽  
Freight Logistics ◽  
Transportation Modes ◽  
Last Mile ◽  
Urban Distribution ◽  
The City

Urban distribution in medium-sized cities faces a major challenge, mainly when deliveries are difficult in the city center due to: an increase of e-commerce, weak public transportation system, and the promotion of urban sustainability plans. As a result, private cars, public transportation, and freight transportation compete for the same space. This paper analyses the current state for freight logistics in the city center of Pamplona (Spain) and proposes alternative transportation routes and transportation modes in the last-mile city center distribution according to different criteria evaluated by residents. An analytic hierarchy process (AHP) was developed. A number of alternatives have been assessed considering routes and transportation modes: the shortest route criterion and avoiding some city center area policies are combined with traditional van-based, bike, and aerial (drone) distribution protocols for delivering parcels and bar/restaurant supplies. These alternatives have been evaluated within a multicriteria framework in which economic, environmental, and social objectives are considered at the same time. The point in this multicriteria framework is that the criteria/alternative AHP weights and priorities have been set according to a survey deployed in the city of Pamplona (Navarre, Spain). The survey and AHP results show the preference for the use of drone or bike distribution in city center in order to reduce social and environmental issues.

scholarly journals Estimating Demand for a New Travel Mode in Boise, Idaho

2021 ◽  
Vol 13 (3) ◽  
pp. 1209
Author(s):  
Mandar Khanal
Keyword(s):  
Road Network ◽  
Travel Demand ◽  
Stated Preference ◽  
State University ◽  
University Campus ◽  
City Center ◽  
Road Congestion ◽  
The Us ◽  
Potential Mode ◽  
The City

The 20,000-student Boise State University campus is located about 3 km from the center of the city of Boise. There is a significant amount of travel between the campus and the city center as students and staff travel to the city to visit restaurants, shops, and entertainment centers. Currently, people make this trip by car, shuttle bus, bike, or walking modes. Cars and shuttle buses, which share the same road network, constitute about 76% of the total trips. As road congestion is expected to grow in the future, it is prudent to look for other modes that can fulfill the travel demand. One potential mode is an aerial tramway. However, an aerial tramway is not a common mode of urban travel in the US. This research describes how the stated preference method was used to estimate demand for a mode that does not currently exist. An online stated preference survey was sent out to 8681 students, faculty, and staff and 1821 valid responses were received. Only about 35% of the respondents expressed their willingness to choose an aerial tramway for various combinations of cost and convenience of the new mode. Respondents were also found to favor convenience over cost for the new mode.

scholarly journals Impact of COVID-19 Pandemic on Retail Structure in Barcelona: From Tourism-Phobia to the Desertification of City Center

2021 ◽  
Vol 13 (15) ◽  
pp. 8215
Author(s):  
Lluís Frago Clols
Keyword(s):  
Multiple Scales ◽  
Real Estate Market ◽  
Structured Interviews ◽  
City Center ◽  
Urban Theory ◽  
The Real Estate ◽  
Tourist Flows ◽  
Before And After ◽  
The Impact ◽  
The City

COVID-19 has meant major transformations for commercial fabric. These transformations have been motivated by the collapse of consumer mobility at multiple scales. We analyzed the impact of the collapse of global tourist flows on the commercial fabric of Barcelona city center, a city that has been a global reference in over-tourism and tourism-phobia. Fieldwork in the main commercial areas before and after the pandemic and complementary semi-structured interviews with the main agents involved highlight the relationship between global tourist flows and commercial fabric. The paper shows how the end of global tourism has meant an important commercial desertification. The end of the integration of the city center into global consumer flows has implications for urban theory. It means a downscaling of the city center and the questioning of traditional center-periphery dynamics. It has been shown that the tourist specialization of commerce has important effects on the real estate market and makes it particularly vulnerable. However, the touristic specialization of commercial activities as a strategy of resilience has also been presented. This adaptation faces the generalized commercial desertification that drives the growing concentration of consumption around the online channel.

scholarly journals Ventilation of a Mid-Size City under Stable Boundary Layer Conditions: A Simulation Using the LES Model PALM

Atmosphere ◽  
2021 ◽  
Vol 12 (3) ◽  
pp. 401
Author(s):  
Jonathan Biehl ◽  
Bastian Paas ◽  
Otto Klemm
Keyword(s):  
Boundary Layer ◽  
Stable Boundary Layer ◽  
Passive Scalar ◽  
City Center ◽  
Street Canyons ◽  
Stable Boundary ◽  
Northwest Germany ◽  
Stable Conditions ◽  
Les Model ◽  
The City

City centers have to cope with an increasing amount of air pollution. The supply of fresh air is crucial yet difficult to ensure, especially under stable conditions of the atmospheric boundary layer. This case study used the PArallelized Large eddy simulation (LES) Model PALM to investigate the wind field over an urban lake that had once been built as a designated fresh air corridor for the city center of Münster, northwest, Germany. The model initialization was performed using the main wind direction and stable boundary layer conditions as input. The initial wind and temperature profiles included a weak nocturnal low-level jet. By emitting a passive scalar at one point on top of a bridge, the dispersion of fresh air could be traced over the lake’s surface, within street canyons leading to the city center and within the urban boundary layer above. The concept of city ventilation was confirmed in principle, but the air took a direct route from the shore of the lake to the city center above a former river bed and its adjoining streets rather than through the street canyons. According to the dispersion of the passive scalar, half of the city center was supplied with fresh air originating from the lake. PALM proved to be a useful tool to study fresh air corridors under stable boundary layer conditions.

scholarly journals New Housing Developments in the City Center of Guadalajara (Mexico): An Analysis from the Perspective of Collective and Sustainable Dwelling

Buildings ◽  
2021 ◽  
Vol 11 (4) ◽  
pp. 168
Author(s):  
Alessandra Cireddu
Keyword(s):  
Point Of View ◽  
City Center ◽  
Compact City ◽  
Housing Developments ◽  
Human Scale ◽  
Horizontal Growth ◽  
Downtown Redevelopment ◽  
Mode Of Transport ◽  
The City ◽  
New Buildings

New vertical housing developments in Guadalajara (Mexico) are reaching the city center as a response for redensification after many years of expansion of the urban area characterized by a suburban, low density and fragmented pattern. This horizontal growth, dominated by use of the automobile as prevailing mode of transport, has proven to be unsustainable not only from an environmental point of view, but also from a social perspective where the “human scale” of the city has been affected, same as the daily life of its inhabitants. On the other hand, vertical housing proposals are by their very nature associated with concepts of redensification, compact city and collective living; the aim of this article is to analyze some new housing developments in Guadalajara downtown in order to evaluate to what extent the new buildings embody a more sustainable, livable and collective dwelling, to discuss findings, successes and failures and thus be able to contribute some conclusions and open a broader reflection about contemporary housing, urban density and downtown redevelopment in Latin America cities through collective and sustainable dwelling.

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