COMPARISON OF SOCIO-DEMOGRAPHIC AND CLINICAL FACTORS AND TREATMENT OUTCOME OF PULMONARY AND EXTRA PULMONARY PEDIATRIC TUBERCULOSIS

2018 ◽  
Author(s):  
Emine Kocabas
Keyword(s):  
Treatment Outcome ◽  
Clinical Factors ◽  
Extra Pulmonary ◽  
Pediatric Tuberculosis

scholarly journals Association of type of tuberculosis with treatment outcome among paediatric tuberculosis patients in Bhopal city

2017 ◽  
Vol 4 (11) ◽  
pp. 4205
Author(s):  
Sheloj Joshi
Keyword(s):  
Treatment Outcome ◽  
Age Groups ◽  
Study Data ◽  
Age Group ◽  
Tuberculosis Patients ◽  
Pulmonary Tb ◽  
Paediatric Patients ◽  
Immunodeficiency Virus ◽  
Extra Pulmonary ◽  
Paediatric Tuberculosis

Background: Tuberculosis causes ill-health among millions of people each year and ranks as the second leading cause of death from an infectious disease worldwide, after the human immunodeficiency virus (HIV).The younger the child, the more are the chances of complications and death from the disease. The objective of the study was to find out the association of type of tuberculosis with the treatment outcome of paediatric TB patients registered under RNTCP in Bhopal city.Methods: A longitudinal study was conducted in all tuberculosis treatment units (TU) of Bhopal city. All paediatric patients in the age group of 0 to 14 years diagnosed as TB and registered under RNTCP and fulfilling inclusion criteria during January 2013 to June 2013 were included in the study. Data regarding paediatric TB patients was collected by using a structured questionnaire. Information was also obtained in two subsequent visits of the patient, one at the end of intensive phase to know the response of treatment and other at the end of the treatment for treatment outcome. The data was analysed on statistical software SPSS vs.20.Results: The present study was conducted on 165 paediatric Tuberculosis patients who were registered for DOTS treatment under RNTCP. Pulmonary TB is common in all the age group of <1 and 1-10 years. Out of 165 paediatric patients,93.33% of patients were treatment completed in which 54.54% were pulmonary cases and 45.45% were extra pulmonary while 4.84% were declared cured, thus showing statistically significant association (X2=9.758 and p=0.04, df=4) between type of Tuberculosis and treatment outcome.Conclusions: Pulmonary TB is common in the age groups of <1 and 1-10 years while in 11-14 years of age group extra pulmonary TB is more common. There is statistically significant association between type of Tuberculosis and treatment outcome. 

scholarly journals Tuberculosis in North-East India: patient profile and treatment outcome of patient attending RNTCP

2019 ◽  
Vol 6 (7) ◽  
pp. 2856
Author(s):  
T. Kayia Priscilla Kayina ◽  
M. Shyami Tarao ◽  
Polly Nula
Keyword(s):  
Treatment Outcome ◽  
Effective Prevention ◽  
Pulmonary Tb ◽  
North East India ◽  
Patient Profile ◽  
North East ◽  
The North ◽  
Number Of Patients ◽  
North Eastern ◽  
Extra Pulmonary

Background: Tuberculosis is a disease of global concern. India with its high burden of Tuberculosis, HIV and HIV-TB co-infection, this disease continue to have tremendous impact on its denizens especially the north-eastern states of the country because of its problem of HIV. It is imperative to understand every aspects of the disease for effective prevention and control.Methods: A retrospective record study of tuberculosis units was conducted.Results: The proportion of males was more as compared to females, with more cases seen with increasing age. Pulmonary TB was seen more among males, whereas extra-pulmonary TB was seen more among females. Favorable treatment outcome was seen in 84.7% of the population. HIV-TB Co-infection was seen 6.5% of the patients, with 46.3% having extra-pulmonary TB. Favorable treatment outcome was seen among them too.Conclusions: More common in males, showing increasing number of patients in older age group with favourable outcomes on treatment in all categories including HIV-TB co-infection patients.

scholarly journals A study of treatment outcomes of pulmonary tuberculosis and extrapulmonary tuberculosis patients in a tertiary care centre

2017 ◽  
Vol 4 (4) ◽  
pp. 1133 ◽  
Author(s):  
V. H. Ramya ◽  
G. Gayathri ◽  
V. Gangadharan
Keyword(s):  
Treatment Outcome ◽  
Success Rate ◽  
Treatment Outcomes ◽  
Tertiary Care ◽  
Care Centre ◽  
Cure Rate ◽  
Tertiary Care Centre ◽  
Tuberculosis Patients ◽  
Pulmonary Tb ◽  
Extra Pulmonary

Background: Directly observed treatment remains one of the most widely-accepted global health interventions for tuberculosis. Tuberculosis treatment outcome is one of the performance indicators of the programme set by World Health Organization.Methods: This study was conducted in a tertiary care centre Chennai. A retrospective analysis of the profile and treatment outcome of all tuberculosis patients registered from January 2015 to December 2015 at DOTS centre under RNTCP was conducted. Data on treatment outcomes was analysed using appropriate statistical methods and percentages were calculated.Results: Out of 118 TB cases, 59.3% had pulmonary while 40.7% had extra-pulmonary TB. Sputum positive PTB is more common than sputum negative which is 74.2% and 25.8% respectively. Frequency of TB lymphadenitis is being the common presentation among extra pulmonary TB cases, followed by TB pleurisy. Success rate (cure rate plus treatment completion rate) for new cases was 63.1% and for retreatment cases was 36.9% while the overall success rate was 81%.Conclusions: Effective measures have to be taken in the programme to move forward to help in the eradication of TB. Tuberculosis mostly affects males of the economically productive age group and causes economic losses. The success rate of new cases was higher compared to retreatment cases though the overall success rate was lower compared to the RNTCP norms. Proper education on DOTS can help in improving the success rate and cure rate.

scholarly journals Treatment outcome of tuberculosis patients and factors determining treatment outcome at peripheral health settings of Northern Ethiopia: a five year retrospective study

2019 ◽  
Author(s):  
Mahmud Abdulkadir ◽  
Ischa van Aken ◽  
Selam Sahle Niguse ◽  
Haftamu Hailekiros ◽  
Mark Spigt
Keyword(s):  
Treatment Outcome ◽  
Retrospective Study ◽  
Treatment Failure ◽  
Treatment Success ◽  
Northern Ethiopia ◽  
Tuberculosis Patients ◽  
Retreatment Case ◽  
National Tuberculosis ◽  
The Mean ◽  
Extra Pulmonary

Abstract Objective Evidences of treatment outcome and identifying factors associated with treatment failure through a register based retrospective study have significant contribution in in the improvement of a National Tuberculosis Program. However there is a scarcity of data from peripheral health settings in Ethiopia. Therefore this study is aimed at determining treatment outcome of tuberculosis patients and associated factors. Results A total of 3471 patient records were included. More than half, (58%) were males and the mean age was 34 ± 17 years. Majority (43%) had extra-pulmonary TB. From the total TB patients, 18.8% were HIV co infected. The overall treatment success was 89.5%. Being HIV coinfected, pulmonary negative, extra-pulmonary and retreatment case were significantly associated with treatment failure.

scholarly journals Relation of Intracerebral Hemorrhage Descriptors with Clinical Factors

2020 ◽  
Vol 10 (4) ◽  
pp. 252
Author(s):  
Kornelia M. Kliś ◽  
Roger M. Krzyżewski ◽  
Borys M. Kwinta ◽  
Krzysztof Stachura ◽  
Tadeusz J. Popiela ◽  
...  
Keyword(s):  
Fractal Dimension ◽  
Treatment Outcome ◽  
Intracerebral Hemorrhage ◽  
General Condition ◽  
Spontaneous Intracerebral Hemorrhage ◽  
Clinical Factors ◽  
Poor Treatment ◽  
Shape Irregularity ◽  
Brain Tissue Damage ◽  
Poor Treatment Outcome

The association between intracerebral hemorrhage (ICH) shape and a poor treatment outcome has been established by few authors. We decided to analyze whether computationally assessed hemorrhage shape irregularity is associated with any known predictors of its poor treatment outcome. We retrospectively analyzed 48 patients with spontaneous intracerebral hemorrhage. For each patient we calculated Fractal Dimension, Compactness, Fourier Factor and Circle Factor. Our study showed that patients above 65 years old had significantly higher Compactness (0.70 ± 0.19 vs. 0.56 ± 0.20; p < 0.01), Fractal Dimension (0.46 ± 0.22 vs. 0.32 ± 0.20; p = 0.03) and Circle Factor (0.51 ± 0.25 vs. 0.35 ± 0.17; p < 0.01). Patients with hemorrhage growth had significantly higher Compactness (0.74 ± 0.23 vs. 0.58 ± 0.18; p < 0.01), Circle Factor (0.55 ± 0.27 vs. 0.37 ± 0.18; p < 0.01) and Fourier Factor (0.96 ± 0.06 vs. 0.84 ± 0.19; p = 0.03). In conclusion, irregularity resulting from the number of appendices can be a predictor of ICH growth; however, the size of those appendices is also important. Shape roughness better reflects the severity of brain tissue damage and a patient’s general condition.

scholarly journals A 5-year experience characterizing the demographic and clinical profile and directly observed treatment short-course treatment outcome in National Tuberculosis Center of Duhok province, Iraqi Kurdistan

2020 ◽  
Vol 8 ◽  
pp. 205031212092105
Author(s):  
Muayad Aghali Merza
Keyword(s):  
Treatment Outcome ◽  
Pulmonary Tuberculosis ◽  
Treatment Outcomes ◽  
Clinical Profile ◽  
Patient Treatment ◽  
Extra Pulmonary Tuberculosis ◽  
Tuberculosis Patients ◽  
National Tuberculosis Program ◽  
National Tuberculosis ◽  
Extra Pulmonary

Background: The objectives were to describe the demographic and clinical profile and treatment outcomes in the National Tuberculosis Program Center of Duhok governorate. Methods: This was a descriptive retrospective study of all forms of drug-susceptible tuberculosis cases in the National Tuberculosis Program Center of Duhok. The Electronic Nominal Recording Reporting System data of tuberculosis cases were reviewed during 2014–2018. Information on the demographic, clinical, and laboratory characteristics of the patients were analyzed. Tuberculosis trends and treatment outcomes were determined. Results: A total of 1063 tuberculosis patients visited the National Tuberculosis Program Center, of whom 905 were from Duhok. The estimated tuberculosis notification rate per 100,000 people in Duhok governorate was 14.06, 16.16, 10.43, 11.05, and 10.34 for the years 2014, 2015, 2016, 2017, and 2018, respectively. The most affected age group was 15–24 years. The male cases were predominant. Most patients (97.3%) were native Iraqi. There were 718 (67.5%) pulmonary tuberculosis cases and 345 (32.5%) extra-pulmonary tuberculosis cases; tuberculosis lymphadenitis was the most common presentation. The majority of extra-pulmonary tuberculosis patients were females aged 15–24 years (p = 0.019), and patients aged ⩾65 years were associated with pulmonary tuberculosis and extra-pulmonary tuberculosis in males (p ⩽ 0.001). The highest tuberculosis incidence occurred in winter (288 patients). The patient treatment outcomes were as follows: 90.7% successful treatment, 1.6% lost to follow-up, 6.7% death, 0.3 transferred out, and 0.8 treatment failure. Conclusion: There was a high frequency of extra-pulmonary tuberculosis, which may reflect overestimation in its diagnosis. Therefore, meticulous evaluations should be provided. The treatment outcome was satisfactory in the center. Hence, we should maintain the favorable work to attain tuberculosis control objectives. Performing GeneXpert for all tuberculosis cases and introducing culture and drug susceptibility testing should be an urgent plan to strengthen the diagnosis of susceptible and drug-resistant tuberculosis cases.

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