31G3D03 - Glycosylation as a means to modulate membrane receptor conformation and visibility

2021 ◽  
Author(s):  
Ilpo Vattulainen
Keyword(s):  
Membrane Receptor ◽  
Receptor Conformation

scholarly journals Understanding the Role of Lipids in Signaling Through Atomistic and Multiscale Simulations of Cell Membranes

2019 ◽  
Vol 48 (1) ◽  
pp. 421-439 ◽  
Author(s):  
Moutusi Manna ◽  
Tuomo Nieminen ◽  
Ilpo Vattulainen
Keyword(s):  
Cell Signaling ◽  
Membrane Receptor ◽  
Coarse Grained ◽  
Multiscale Simulations ◽  
Structural Modifications ◽  
Cellular Processes ◽  
Dynamics And Control ◽  
And Control ◽  
Receptor Conformation

Cell signaling controls essentially all cellular processes. While it is often assumed that proteins are the key architects coordinating cell signaling, recent studies have shown more and more clearly that lipids are also involved in signaling processes in a number of ways. Lipids do, for instance, act as messengers, modulate membrane receptor conformation and dynamics, and control membrane receptor partitioning. Further, through structural modifications such as oxidation, the functions of lipids as part of signaling processes can be modified. In this context, in this article we discuss the understanding recently revealed by atomistic and coarse-grained computer simulations of nanoscale processes and underlying physicochemical principles related to lipids’ functions in cellular signaling.

Nano-Mechanics and Membrane Receptor Mapping of CD8 + T Cells (Supplementry Material)

2009 ◽  
Vol 5 (4) ◽  
pp. 465-469
Author(s):  
Yangzhe Wu ◽  
Yi Hu ◽  
Hongsong Lu ◽  
Jiye Cai ◽  
Xianhui He ◽  
...  
Keyword(s):  
T Cells ◽  
Cd8 T Cells ◽  
Membrane Receptor ◽  
Receptor Mapping
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