Impulse Control Disorders in Parkinson’s Disease: Pathophysiology, Effect of Genetic Polymorphism and Future Research Directions

Author(s):  
Bhattacharjee S
2021 ◽  
Vol 11 (2) ◽  
pp. 185
Author(s):  
Amit Abraham ◽  
Ryan P. Duncan ◽  
Gammon M. Earhart

Parkinson’s disease (PD) is a disabling neurodegenerative disease whose manifestations span motor, sensorimotor, and sensory domains. While current therapies for PD include pharmacological, invasive, and physical interventions, there is a constant need for developing additional approaches for optimizing rehabilitation gains. Mental imagery is an emerging field in neurorehabilitation and has the potential to serve as an adjunct therapy to enhance patient function. Yet, the literature on this topic is sparse. The current paper reviews the motor, sensorimotor, and sensory domains impacted by PD using gait, balance, and pain as examples, respectively. Then, mental imagery and its potential for PD motor and non-motor rehabilitation is discussed, with an emphasis on its suitability for addressing gait, balance, and pain deficits in people with PD. Lastly, future research directions are suggested.


2011 ◽  
Vol 2011 ◽  
pp. 1-11 ◽  
Author(s):  
Lorinda C. Kwan ◽  
Tara L. Whitehill

A few clinical reports and empirical studies have suggested a possible deficit in the perception of speech in individuals with Parkinson's disease. In this paper, these studies are reviewed in an attempt to support clinical anecdotal observations by relevant empirical research findings. The combined evidence suggests a possible deficit in patients' perception of their own speech loudness. Other research studies on the perception of speech in this population were reviewed, in a broader scope of the perception of emotional prosody. These studies confirm that Parkinson's disease specifically impairs patients' perception of verbal emotions. However, explanations of the nature and causes of this perceptual deficit are still limited. Future research directions are suggested.


2017 ◽  
Vol 125 (2) ◽  
pp. 131-143 ◽  
Author(s):  
Alice Martini ◽  
Simon J. Ellis ◽  
James A. Grange ◽  
Stefano Tamburin ◽  
Denise Dal Lago ◽  
...  

2013 ◽  
Vol 23 ◽  
pp. S548-S549
Author(s):  
O.A. Van den Heuvel ◽  
C. Vriend ◽  
A.H. Nordbeck ◽  
J. Booij ◽  
Y.D. Van der Werf ◽  
...  

2016 ◽  
Vol 31 (4) ◽  
pp. 231-238 ◽  
Author(s):  
N. Sáez-Francàs ◽  
G. Martí Andrés ◽  
N. Ramírez ◽  
O. de Fàbregues ◽  
J. Álvarez-Sabín ◽  
...  

2021 ◽  
Vol 12 ◽  
Author(s):  
Jun-Fang Zhang ◽  
Xi-Xi Wang ◽  
Ya Feng ◽  
Robert Fekete ◽  
Joseph Jankovic ◽  
...  

Impulse control disorders (ICDs) in Parkinson's disease (PD) are aberrant behavior such as pathological gambling, hypersexuality, binge eating, and compulsive buying, which typically occur as a result of dopaminergic therapy. Numerous studies have focused on the broad spectrum of ICDs-related behaviors and their tremendous impact on patients and their family members. Recent advances have improved our understanding of ICDs. In this review, we discuss the epidemiology, pathogenesis and treatment of ICDs in the setting of PD.


2012 ◽  
Vol 34 (7) ◽  
pp. 1207-1213 ◽  
Author(s):  
Anna Rita Bentivoglio ◽  
Eleonora Baldonero ◽  
Lucia Ricciardi ◽  
Francesca De Nigris ◽  
Antonio Daniele

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