MRI Brain Documentation

2021 ◽  
Vol 8 (2) ◽  
Author(s):  
Alahmari A ◽  
Keyword(s):  
Brain Mri ◽  
Normal Brain ◽  
Neurological Abnormality ◽  
Mri Scan ◽  
Medical File ◽  
Mri Brain ◽  
Picture Archiving ◽  
Neurological Event ◽  
Mri Study ◽  
The Brain

In many clinical cases, a patient may come to the hospital with a neurological abnormality. This patient happen to have a normal brain MRI study that is recorded on the Picture Archiving and Communicating system (PACs) of that hospital. The previous normal study will help in identifying any pathology take place in the future easily. What if all the patients did have a previous studies for the brain as some kind of documentation? It will help a lot. The aim of this paper is to propose a new idea that required for all the citizens in a country to have a normal brain MRI study recorded on their medical file and this MRI study updated every five years by undertaking an MRI scan. The usefulness of this idea can be imply in different ways. For example; when a patient affected by any type of neurological issue, we have a morphological documentation for the brain prior to that neurological event took a place. As well, this is will provide a database for researchers to find pre and post neurological event documentation. Furthermore, it will help in detecting and documenting senile atrophic changes over the time. Sometime patients will have a “silent stroke” which has no symptoms which can be detected by the brain MRI scan.

Evaluation of brain iron content in Egyptian Patients with Sickle cell disease and its impact on Neurocognitive functions

QJM ◽  
2021 ◽  
Vol 114 (Supplement_1) ◽  
Author(s):  
Mohsen Saleh Elalfy ◽  
Fatma Soliman Elsayed Ebeid ◽  
Mohammed Ahmed Samir Ibrahim ◽  
Hanaa Midhat Abdel Gader Hussein
Keyword(s):  
Iron Overload ◽  
Brain Mri ◽  
Healthy Controls ◽  
Brain Iron ◽  
Cell Disease ◽  
Neurocognitive Functions ◽  
The Difference ◽  
Mri Study ◽  
The Brain ◽  
Age And Sex

Abstract Background Sickle cell disease (SCD) is considered the most prevalent monogenic diseases worldwide. Iron overload is one of the major complications in those patients, especially who in need for frequent transfusion, affecting many organs including the brain. MRI is a valuable, reliable and non-invasive method for quantifying iron concentration in many organs as the liver and heart and it is now used for monitoring of the chelation therapy in SCD patients. Several studies began reporting differences in global cognitive function, particularly for children with SCD, they are at a high risk for neurocognitive impairment they often scored lower on general IQ measures than healthy children which is due to iron overload in brain tissue from the chronic transfusions which can lead to strokes and may be a silent stroke. Objective The current study assessed brain iron content (using R2* values) in the caudate and thalamic regions through quantitative brain MRI study in SCD patients in comparison to age and sex-matched healthy controls. Methods A case-control study recruited 32 patients with SCD and 11 healthy controls. Brain MRI study using multi-echo fast gradient echo sequence was done for all the patients and controls. Brain R2* values of both caudate and thalamic regions (right and left sides) were calculated for only 15 SCD patients and the 11 controls. All recruited SCD patients and controls were examined for the neurocognitive functions by these tests: Wechsler IV Intelligence Scale for Adult shows (Verbal, Perceptual, Memory, Processing and Total IQ), their all normal values between 90 – 110. Benton Visual Retention Test have cut of point at (> 4 or = 4). Those values are the same for the difference between the obtained correct and the expected correct, and the difference between the obtained error and expected error. Results The fifteen patient with SCD who underwent brain MRI were age and sex matched with the eleven healthy control (15 SCD patients: mean-age: 16.93 ± 3.41 years, 40.6% females and 11healthy controls: mean age: 18.73 ± 4.84 years, 54.5% females) were enrolled in the study. As regards the brain MRI, there was no statistically significant differences between SCD and control group in all regions of interests (p > 0.05). Our study showed that 72.7% of our SCD patients had under threshold TIQ scores. Also18% of the patients showed moderate anxiety, 9% mild anxiety and 9% showed severe anxiety. Conclusion The results of our study showed that even in cases of iron overload which affects vital organs as the liver, cardiac and brain iron overload don't occur.

scholarly journals Analysis on the MRI and BAEP  Results of Neonatal Brain with Different Levels of Bilirubin

2020 ◽  
Author(s):  
LU ZHONGXING ◽  
SHOULING DING ◽  
FEN WANG ◽  
Haitao Lv
Keyword(s):  
Central Nervous System ◽  
Brain Mri ◽  
Full Term ◽  
Normal Brain ◽  
Central Nervous System Damage ◽  
Severe Group ◽  
The Difference ◽  
The Brain ◽  
Abnormal Ratio ◽  
Abnormal Brain

Abstract Background：To explore whether there is abnormality of neonatal brains’ MRI and BAEP with different bilirubin levels, and to provide an objective basis for early diagnosis on the bilirubin induced subclinical damage on brains.Methods: To retrospectively analyze the clinical data of 103 neonatal patients, who had been hospitalized in Neonatology Department of Taicang First People’s Hospital from March 2013 to September 2015, to conduct routine brain MRI examination , BAEP testing and to analyze BAEP and MRI image results of the neonatal patients, who were divided into three groups based on the levels of total serum bilirubin concentration (TSB), 16 cases in mild group (TSB:0.0~229.0μmol/L), 49 cases in moderate group (TSB: 229.0~342.0μmol/L) and 38 cases in severe group (TSB≥342.0μmol/L); Results: We found as follows: A. Comparison of the bilirubin value of the different group : 1. The bilirubin value of the mild group is 171.99±33.50 μmol/L, the moderate group is293.98±32.09 μmol/L, and the severe group is 375.59±34.25 μmol /L . And the comparison of bilirubin values of the three groups of neonates (P＜0.01) indicates the difference is statistically significant (P＜0.01). 2. The bilirubin value of the pre-term group is 289.70±85.38μmol/Land the full-term group is 310.36±72.32 μmol/L, but the comparison of the bilirubin values between pre-term group and full-term group indicates that the difference is not statistically significant (P＞0.05).3. The bilirubin value of the normal brain MRI group(82) is 305.55±74.54 μmol/L and the abnormal brain MRI group is 303.56±83.04μmol/L; the comparison of bilirubin values between the two groups indicates that the difference is not statistically significant(P＞0.05). B. The weight value of the ﹤2500g group is 2.04±0.21 and the ≥2500ggroup is 3.39±0.46; the weight comparison of the two groups indicates that the difference is statistically significant (P＜0.01). C. Comparison of the abnormal MRI of the different groups: 1.The brain MRI result's abnormal ratio of the mild group is 31.25%, the moderate group is 16.33% and the severe group is 21.05%, but the comparison of brain MRI results of the three neonates groups indicates that the difference is not statistically significant (P＞0.05). 2.The brain MRI result's abnormal ratio of the pre-term is 30.77% and the full-term group is 16.88%, but the comparison of brain MRI results between prem-term group and full-term group indicates that the difference is not statistically significant (P＞0.05). 3.The brain MRI result's abnormal ratio of the ﹤2500g group is 37.50% and the ≥2500g group is 17.24%; but the comparison of brain MRI results of two neonates groups indicates that the difference is not statistically significant(P＞0.05). D. Comparison of abnormal MRI signal values of globus pallidus on T1WI in different groups: 1. The comparison of normal group signal values with that of mild group (p < 0.05), with that of moderate group and with that of severe group (p < 0.01) indicates that the difference is statistically significant; 2. The comparison of signal values between mild and moderate groups (p < 0.05) and between mild group and severe group (p < 0.01) indicates that the difference is statistically significant; 3. The comparison of signal values between moderate group and severe group indicates that the difference is statistically significant(p < 0.05). E. Comparison of BAEP testing results in groups: 1. There were 27(26.21%) cases in abnormalities of the BAEP results of all 103cases bilirubin patients. 2. There were 15(18.29%) cases in abnormalities of the BAEP result of the 82 cases normal brain MRL , 2(40%) cases in abnormalities of the BAEP result of the 5 cases abnormal MRI in mild bilirubin group, 4（50%） cases in abnormalities of the BAEP result of the 8 cases abnormal MRI in moderate bilirubin group and 6（75%）cases in abnormalities of the BAEP result of the 8 cases abnormal brain MRI in severe bilirubin group. 3. After one month review of the BAEP result, there was 0（0.00%） abnormal case in the normal MRI and the mild group; there were 1（20%） abnormal case in the moderate group and 2（25%） cases in the severe group. Conclusion: At low level of bilirubin, central nervous system damage may also occur and can be detected as abnormality by MRI and BAEP. Meanwhile, MRI and BAEP can also provide early abnormal information for the judgment of central nervous system damage of the children with NHB who have no acute bilirubin encephalopathy (ABE) clinical features, and provide clues for early treatment and early intervention.

scholarly journals Extricating Brain Tumor in MRI Images with the aid of MATLAB software

2021 ◽  
Vol 9 (VII) ◽  
pp. 502-506
Author(s):  
Shivam Kumar Mittal
Keyword(s):  
Image Processing ◽  
Brain Tumor ◽  
Image Quality ◽  
Brain Mri ◽  
Medical Science ◽  
Noise Removal ◽  
Mri Scan ◽  
Matlab Software ◽  
The Brain ◽  
Mri Image

In the current era of Medical Science, Image Processing is the most evolving and inspiring technique. This technique consolidates some noise removal functions, segmentation, and morphological activities which are the fundamental ideas of image processing. Initially preprocessing of an MRI image is done to ensure the image quality for further processing/output. Our paper portrays the methodology to extricate and diagnose the brain tumor with the help of an affected person’s MRI scan pictures of the brain. MRI pictures are taken into account to recognize and extricate the tumor from the brain with the aid of MATLAB software.

scholarly journals Cavernoma of the lateral ventricule presenting as speech arrests

2014 ◽  
Vol 33 (01) ◽  
pp. 82-84
Author(s):  
Leonardo Conrado Silva Lima ◽  
Marcelo Paglioli Ferreira ◽  
Davidson Alba ◽  
Alisson Roberto Teles ◽  
Frederico Kliemann
Keyword(s):  
Neurological Examination ◽  
Brain Mri ◽  
Cavernous Haemangioma ◽  
Total Resection ◽  
Cavernous Malformations ◽  
Transcallosal Approach ◽  
Vascular Channels ◽  
Thin Walled ◽  
Mri Study ◽  
The Brain

AbstractCavernous malformations (CM) are formed by dilated thin-walled vascular channels without intervening parenchyma and intraventricular lesions are rare. We report a case of an intraventricular cavernoma in a 54-year old female patient. She presented with speech arrests daily for 10 months. Neurological examination revealed no deficits. The brain MRI study revealed an intraventricular lesion at the level of the left atrium, heterogeneously hyperintense on both T1 and T2-weighted images. It was performed an interhemispheric transcallosal approach with gross-total resection of the lesion. The histological examination was compatible with the diagnosis of cavernous haemangioma. In the postoperative period the patient presented with transient right hemiparesis with recovery in two weeks. We briefly review the literature concerning intraventricular cavernomas.

scholarly journals Clinical and Radiological Profiles of COVID-19 Patients with Neurological Symptomatology: A Comparative Study

Viruses ◽  
2021 ◽  
Vol 13 (5) ◽  
pp. 845
Author(s):  
Maria de Fatima Viana Vasco Aragao ◽  
Mariana de Carvalho Leal ◽  
Pedro Henrique Pereira Andrade ◽  
Ocelio Queiroga Cartaxo Filho ◽  
Lucas Vasco Aragao ◽  
...  
Keyword(s):  
Brain Mri ◽  
Chest Ct ◽  
Neurological Involvement ◽  
Mechanical Ventilator ◽  
Mri Scan ◽  
Olfactory Bulbs ◽  
Brain Ct ◽  
Significant Difference ◽  
Brain Scan ◽  
The Brain

Patients with COVID-19 can require radiological examination, with chest CT being more frequent than neuro-imaging. The objective is to identify epidemiological, clinical and radiological factors considered as predictors of neurological involvement in patients with COVID-19 assessed by neuroimaging and to describe the neuroimaging findings. This retrospective study was performed with 232 consecutive confirmed COVID-19 patients, from two radiological units, which were divided into two groups: (1) those who underwent a brain CT/MRI scan (n = 35) versus (2) those who did not undergo the brain CT/MRI scan, but underwent only chest CT (n = 197). There was a statistically significant difference with associations regarding the COVID-19 brain scan group for: admission to ICU, greater severity of lung injuries, the use of a mechanical ventilator and sepsis. Statistical tendency was found for chronic renal failure and systemic arterial hypertension. Forty-percent of COVID-19 patients from the brain scan group were abnormal on brain CT and/or brain MRI (22.9% of the cases with bleeding or microbleeding, 8.6% with restricted diffusion lesions). One ischemic stroke case was associated with irregularity at the M1 segment of the right middle cerebral artery. There was a case of left facial nerve palsy with enhancement of the left geniculate ganglia. An analysis of the olfactory bulbs was possible in 12 brain MRIs and 100% had enhancement and/or microbleeding. In conclusion, a more severe COVID-19 disease from ICU, a more severe form of lung disease, the use of mechanical ventilator and sepsis were associated to the COVID-19 patients with neurological involvement who had undergone brain scans. Microvascular phenomenon was a frequent finding in the brain and olfactory bulbs evaluated by neuroimaging.

Design and Development of 3D Brain MRI System Using Deep Neural Networks

2021 ◽  
Vol 11 (10) ◽  
pp. 2653-2659
Author(s):  
M. Vadivel ◽  
R. Ganesan
Keyword(s):  
Brain Tumor ◽  
Deep Neural Networks ◽  
Brain Mri ◽  
Research Work ◽  
Specific Region ◽  
Classification Algorithms ◽  
Normal Brain ◽  
Proposed Model ◽  
Abnormal Cells ◽  
The Brain

A Brain tumor is otherwise known as intracranial tumor. It is a formation of abnormal cells within the brain. A tumor cells grows continuously in the brain and destroys the cells in that specific region causing brain damage. The main problem in the tumor detection is that some normal brain cells tend to behave as tumor cell which leads to misclassification or unwanted brain surgery. A great challenge for the researchers is to identify the region and appropriate tumor mass. Due to this main reason, automated classifications are acquired for the early detection of brain tumor. In this research work, two standard datasets were used to test the developed classification algorithms. In this study, four different deep learning models were utilized to identify the accurate fit model to classify the brain tumor. From the results, it was observed that googlenet has achieved maximum mean classification accuracy of 98.2%, sensitivity 98.67% and specificity 96.17%. Our proposed model can be used to classify the brain tumor more accurately and effectively.

scholarly journals Hypermetabolism of basal ganglia in chorea associated with antiphospholipid antibodies demonstrated by F-18 FDG

1997 ◽  
Vol 2 (4) ◽  
pp. 14
Author(s):  
M. M. Sathekge ◽  
A. Maes ◽  
V. Thijst ◽  
M. De Roo
Keyword(s):  
Basal Ganglia ◽  
Antiphospholipid Syndrome ◽  
Cerebral Angiography ◽  
Fdg Pet ◽  
Antiphospholipid Antibodies ◽  
Brain Mri ◽  
Unknown Origin ◽  
Normal Brain ◽  
Primary Antiphospholipid Syndrome ◽  
The Brain

A brain FDG PET study was performed on a 21-year-old woman with subacute chorea of unknown origin. Associated with her chorea, she had abnormal levels of antiphospholipid antibodies. She had none of the classical features of SLE nor primary antiphospholipid syndrome. The images showed high F-18 FDG uptake in the basal ganglia, while the brain MRI and EEG were normal. An association between chorea and antiphospholipid antibodies had been demonstrated before, with normal brain CT, MRI, 123IMPSPECT and cerebral angiography. The report suggests the advantage of FDG PET in imaging of unexplained cases of chorea associated with antiphospholipid antibodies.

scholarly journals Analysis on the MRI and BAEP  Results of Neonatal Brain with Different Levels of Bilirubin

2020 ◽  
Author(s):  
Lu Zhongxing ◽  
Shouling Ding ◽  
Fen Wang ◽  
Haitao Lv
Keyword(s):  
Central Nervous System ◽  
Brain Mri ◽  
Full Term ◽  
Normal Brain ◽  
Central Nervous System Damage ◽  
Severe Group ◽  
The Difference ◽  
The Brain ◽  
Abnormal Ratio ◽  
Abnormal Brain

Abstract Background：To explore whether there is abnormality of neonatal brains’ MRI and BAEP with different bilirubin levels, and to provide an objective basis for early diagnosis on the bilirubin induced subclinical damage on brains.Methods: To prospective study: analyze the clinical data of 103 neonatal patients, who had been hospitalized in Neonatology Department of Taicang First People’s Hospital from March 2013 to September 2015, to conduct routine brain MRI examination , BAEP testing and to analyze BAEP and MRI image results of the neonatal patients, who were divided into three groups based on the levels of total serum bilirubin concentration (TSB), 16 cases in mild group (TSB:0.0~229.0μmol/L), 49 cases in moderate group (TSB: 229.0~342.0μmol/L) and 38 cases in severe group (TSB≥342.0μmol/L); Results: We found as follows: A. Comparison of the bilirubin value of the different group : 1. The bilirubin value of the mild group is 171.99±33.50 μmol/L, the moderate group is293.98±32.09 μmol/L, and the severe group is 375.59±34.25 μmol /L . And the comparison of bilirubin values of the three groups of neonates (P＜0.01) indicates the difference is statistically significant (P＜0.01). 2. The bilirubin value of the pre-term group is 289.70±85.38μmol/Land the full-term group is 310.36±72.32 μmol/L, but the comparison of the bilirubin values between pre-term group and full-term group indicates that the difference is not statistically significant (P＞0.05).3. The bilirubin value of the normal brain MRI group(82) is 305.55±74.54 μmol/L and the abnormal brain MRI group is 303.56±83.04μmol/L; the comparison of bilirubin values between the two groups indicates that the difference is not statistically significant(P＞0.05). B. The weight value of the ﹤2500g group is 2.04±0.21 and the ≥2500ggroup is 3.39±0.46; the weight comparison of the two groups indicates that the difference is statistically significant (P＜0.01). C. Comparison of the abnormal MRI of the different groups: 1.The brain MRI result's abnormal ratio of the mild group is 31.25%, the moderate group is 16.33% and the severe group is 21.05%, but the comparison of brain MRI results of the three neonates groups indicates that the difference is not statistically significant (P＞0.05). 2.The brain MRI result's abnormal ratio of the pre-term is 30.77% and the full-term group is 16.88%, but the comparison of brain MRI results between prem-term group and full-term group indicates that the difference is not statistically significant (P＞0.05). 3.The brain MRI result's abnormal ratio of the ﹤2500g group is 37.50% and the ≥2500g group is 17.24%; but the comparison of brain MRI results of two neonates groups indicates that the difference is not statistically significant(P＞0.05). D. Comparison of abnormal MRI signal values of globus pallidus on T1WI in different groups: 1. The comparison of normal group signal values with that of mild group (p < 0.05), with that of moderate group and with that of severe group (p < 0.01) indicates that the difference is statistically significant; 2. The comparison of signal values between mild and moderate groups (p < 0.05) and between mild group and severe group (p < 0.01) indicates that the difference is statistically significant; 3. The comparison of signal values between moderate group and severe group indicates that the difference is statistically significant(p < 0.05). E. Comparison of BAEP testing results in groups: 1. There were 27(26.21%) cases in abnormalities of the BAEP results of all 103cases bilirubin patients. 2. There were 15(18.29%) cases in abnormalities of the BAEP result of the 82 cases normal brain MRL , 2(40%) cases in abnormalities of the BAEP result of the 5 cases abnormal MRI in mild bilirubin group, 4（50%） cases in abnormalities of the BAEP result of the 8 cases abnormal MRI in moderate bilirubin group and 6（75%）cases in abnormalities of the BAEP result of the 8 cases abnormal brain MRI in severe bilirubin group. 3. After one month review of the BAEP result, there was 0（0.00%） abnormal case in the normal MRI and the mild group; there were 1（20%） abnormal case in the moderate group and 2（25%） cases in the severe group. Conclusion: At low level of bilirubin, central nervous system damage may also occur and can be detected as abnormality by MRI and BAEP. Meanwhile, MRI and BAEP can also provide early abnormal information for the judgment of central nervous system damage of the children with NHB who have no acute bilirubin encephalopathy (ABE) clinical features, and provide clues for early treatment and early intervention.

Metallic prions

2004 ◽  
Vol 71 ◽  
pp. 193-202 ◽  
Author(s):  
David R Brown
Keyword(s):  
Prion Protein ◽  
Binding Capacity ◽  
Normal Function ◽  
Transmissible Spongiform Encephalopathies ◽  
Published Data ◽  
Normal Brain ◽  
Copper Binding ◽  
Loss Of Function ◽  
Spongiform Encephalopathies ◽  
The Brain

Prion diseases, also referred to as transmissible spongiform encephalopathies, are characterized by the deposition of an abnormal isoform of the prion protein in the brain. However, this aggregated, fibrillar, amyloid protein, termed PrPSc, is an altered conformer of a normal brain glycoprotein, PrPc. Understanding the nature of the normal cellular isoform of the prion protein is considered essential to understanding the conversion process that generates PrPSc. To this end much work has focused on elucidation of the normal function and activity of PrPc. Substantial evidence supports the notion that PrPc is a copper-binding protein. In conversion to the abnormal isoform, this Cu-binding activity is lost. Instead, there are some suggestions that the protein might bind other metals such as Mn or Zn. PrPc functions currently under investigation include the possibility that the protein is involved in signal transduction, cell adhesion, Cu transport and resistance to oxidative stress. Of these possibilities, only a role in Cu transport and its action as an antioxidant take into consideration PrPc's Cu-binding capacity. There are also more published data supporting these two functions. There is strong evidence that during the course of prion disease, there is a loss of function of the prion protein. This manifests as a change in metal balance in the brain and other organs and substantial oxidative damage throughout the brain. Thus prions and metals have become tightly linked in the quest to understand the nature of transmissible spongiform encephalopathies.

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