scholarly journals Designing Iron Oxide Nanoparticles for Image Guided Thermal Medicine Applications

2019 ◽  
Author(s):  
Hattie Ring ◽  
Sheng Tong ◽  
Zhe Gao ◽  
Navid Manuchehrabadi ◽  
Kaiyi Jiang ◽  
...  
Keyword(s):  
Magnetic Field ◽  
Iron Oxide ◽  
Field Strength ◽  
Iron Oxide Nanoparticles ◽  
Absorption Rate ◽  
Specific Absorption Rate ◽  
Oxide Nanoparticles ◽  
Image Guided ◽  
The Magnetic Field ◽  
The Ideal

This work evaluates MRI relaxation and the specific absorption rate properties of iron oxide nanoparticles (IONPs) as a function of diameter (6-32 nm). We conclude that the ideal IONP diameter for image guided heating applications is dependent on the magnetic field strength of the MRI for the intended application. <br>

scholarly journals Designing Iron Oxide Nanoparticles for Image Guided Thermal Medicine Applications

2019 ◽  
Author(s):  
Hattie Ring ◽  
Sheng Tong ◽  
Zhe Gao ◽  
Navid Manuchehrabadi ◽  
Kaiyi Jiang ◽  
...  
Keyword(s):  
Magnetic Field ◽  
Iron Oxide ◽  
Field Strength ◽  
Iron Oxide Nanoparticles ◽  
Absorption Rate ◽  
Specific Absorption Rate ◽  
Oxide Nanoparticles ◽  
Image Guided ◽  
The Magnetic Field ◽  
The Ideal

This work evaluates MRI relaxation and the specific absorption rate properties of iron oxide nanoparticles (IONPs) as a function of diameter (6-32 nm). We conclude that the ideal IONP diameter for image guided heating applications is dependent on the magnetic field strength of the MRI for the intended application. <br>

Quantifying intra- and extracellular aggregation of iron oxide nanoparticles and its influence on specific absorption rate

Nanoscale ◽  
2016 ◽  
Vol 8 (35) ◽  
pp. 16053-16064 ◽  
Author(s):  
Seongho Jeon ◽  
Katie R. Hurley ◽  
John C. Bischof ◽  
Christy L. Haynes ◽  
Christopher J. Hogan
Keyword(s):  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Absorption Rate ◽  
Specific Absorption Rate ◽  
Oxide Nanoparticles ◽  
Specific Absorption

scholarly journals Controlling structural and magnetic properties of IONPs by aqueous synthesis for improved hyperthermia

RSC Advances ◽  
2017 ◽  
Vol 7 (22) ◽  
pp. 13159-13170 ◽  
Author(s):  
Debora Bonvin ◽  
Alla Arakcheeva ◽  
Angel Millán ◽  
Rafael Piñol ◽  
Heinrich Hofmann ◽  
...  
Keyword(s):  
Magnetic Properties ◽  
Iron Oxide ◽  
Saturation Magnetization ◽  
Iron Oxide Nanoparticles ◽  
Absorption Rate ◽  
Specific Absorption Rate ◽  
Oxide Nanoparticles ◽  
Aqueous Synthesis ◽  
Vacancy Ordering ◽  
Structural And Magnetic Properties

Introducing a hydrothermal step after coprecipitation leads to iron oxide nanoparticles with higher vacancy ordering, saturation magnetization and specific absorption rate.

scholarly journals Hyperthermia Efficiency of Magnetic Nanoparticles in Dense Aggregates of Cerium Oxide/Iron Oxide Nanoparticles

2018 ◽  
Vol 8 (8) ◽  
pp. 1241 ◽  
Author(s):  
Cindy Yadel ◽  
Aude Michel ◽  
Sandra Casale ◽  
Jerome Fresnais
Keyword(s):  
Iron Oxide ◽  
Magnetic Nanoparticles ◽  
Iron Oxide Nanoparticles ◽  
Absorption Rate ◽  
Specific Absorption Rate ◽  
Oxide Nanoparticles ◽  
Strong Impact ◽  
Heating Efficiency ◽  
Nanoparticles Dispersion

Iron oxide nanoparticles are intended to be used in bio-applications for drug delivery associated with hyperthermia. However, their interactions with complex media often induces aggregation, and thus a detrimental decrease of their heating efficiency. We have investigated the role of iron oxide nanoparticles dispersion into dense aggregates composed with magnetic/non-magnetic nanoparticles and showed that, when iron oxide nanoparticles were well-distributed into the aggregates, the specific absorption rate reached 79% of the value measured for the well-dispersed case. This study should have a strong impact on the applications of magnetic nanoparticles into nanostructured materials for therapy or catalysis applications.

Magnetic targeting with superparamagnetic iron oxide nanoparticles for in vivo glioma

2017 ◽  
Vol 6 (5) ◽  
pp. 449-472 ◽  
Author(s):  
Marina Fontes de Paula Aguiar ◽  
Javier Bustamante Mamani ◽  
Taylla Klei Felix ◽  
Rafael Ferreira dos Reis ◽  
Helio Rodrigues da Silva ◽  
...  
Keyword(s):  
Magnetic Field ◽  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Superparamagnetic Iron Oxide ◽  
Superparamagnetic Iron Oxide Nanoparticles ◽  
Process Efficiency ◽  
Cochrane Library ◽  
Oxide Nanoparticles ◽  
Magnetic Targeting

AbstractThe purpose of this study was to review the use of the magnetic targeting technique, characterized by magnetic driving compounds based on superparamagnetic iron oxide nanoparticles (SPIONs), as drug delivery for a specific brain locus in gliomas. We reviewed a process mediated by the application of an external static magnetic field for targeting SPIONs in gliomas. A search of PubMed, Cochrane Library, Scopus, and Web of Science databases identified 228 studies, 23 of which were selected based on inclusion criteria and predetermined exclusion criteria. The articles were analyzed by physicochemical characteristics of SPIONs used, cell types used for tumor induction, characteristics of experimental glioma models, magnetic targeting technical parameters, and analysis method of process efficiency. The study shows the highlights and importance of magnetic targeting to optimize the magnetic targeting process as a therapeutic strategy for gliomas. Regardless of the intensity of the patterned magnetic field, the time of application of the field, and nanoparticle used (commercial or synthesized), all studies showed a vast advantage in the use of magnetic targeting, either alone or in combination with other techniques, for optimized glioma therapy. Therefore, this review elucidates the preclinical and therapeutic applications of magnetic targeting in glioma, an innovative nanobiotechnological method.

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