scholarly journals N,N’-bis(2-(benzylthio)ethyl)malonamides: Synthesis, Electronic and Steric effects in Silver(I) Extraction and Silver(I) Binding Studies

2020 ◽  
Author(s):  
Abiodun Aderibigbe ◽  
Andrew J. Clark
Keyword(s):  
Room Temperature ◽  
Extraction Efficiency ◽  
Liquid Extraction ◽  
Tetrahedral Coordination ◽  
Binding Studies ◽  
Liquid Liquid Extraction ◽  
Negative Effect ◽  
High Yields ◽  
Electronic And Steric Effects ◽  
Sulfur Donor

Unsubstituted and gem-diethyl substituted malonamide derivatives, bearing benzylthio arms were prepared in moderate to high yields at room temperature. It was observed that electronics effects at the 4-aryl position in the malonamide derivatives had a significant effect on the selectivity, but little effect on silver(I) extraction efficiency measured by liquid-liquid extraction experiments (with the 4-methoxy analogue proving the most selective). Increased steric hindrance near the sulfur donor had a small negative effect on silver(I) extraction efficiency, while hindrance at the methylene centre reduces selectivity. One of the malonamide derivatives prepared was found to bind to silver(I) in a 1:1 fashion suggesting a tetrahedral coordination type.

scholarly journals N,N’-bis(2-(benzylthio)ethyl)malonamides: Synthesis, Electronic and Steric effects in Silver(I) Extraction and Silver(I) Binding Studies

2020 ◽  
Author(s):  
Abiodun Aderibigbe ◽  
Andrew J. Clark
Keyword(s):  
Room Temperature ◽  
Extraction Efficiency ◽  
Liquid Extraction ◽  
Tetrahedral Coordination ◽  
Binding Studies ◽  
Liquid Liquid Extraction ◽  
Negative Effect ◽  
High Yields ◽  
Electronic And Steric Effects ◽  
Sulfur Donor

Unsubstituted and gem-diethyl substituted malonamide derivatives, bearing benzylthio arms were prepared in moderate to high yields at room temperature. It was observed that electronics effects at the 4-aryl position in the malonamide derivatives had a significant effect on the selectivity, but little effect on silver(I) extraction efficiency measured by liquid-liquid extraction experiments (with the 4-methoxy analogue proving the most selective). Increased steric hindrance near the sulfur donor had a small negative effect on silver(I) extraction efficiency, while hindrance at the methylene centre reduces selectivity. One of the malonamide derivatives prepared was found to bind to silver(I) in a 1:1 fashion suggesting a tetrahedral coordination type.

scholarly journals Liquid-Liquid Extraction in Systems Containing Butanol and Ionic Liquids – A Review

2017 ◽  
Vol 38 (1) ◽  
pp. 97-110 ◽  
Author(s):  
Artur Kubiczek ◽  
Władysław Kamiński
Keyword(s):  
Ionic Liquids ◽  
Room Temperature ◽  
Liquid Extraction ◽  
Butanol Production ◽  
Model Liquid ◽  
New Class ◽  
Liquid Liquid Extraction ◽  
Liquid Systems ◽  
Nrtl Equation ◽  
Equilibrium Data

AbstractRoom-temperature ionic liquids (RTILs) are a moderately new class of liquid substances that are characterized by a great variety of possible anion-cation combinations giving each of them different properties. For this reason, they have been termed as designer solvents and, as such, they are particularly promising for liquid-liquid extraction, which has been quite intensely studied over the last decade. This paper concentrates on the recent liquid-liquid extraction studies involving ionic liquids, yet focusing strictly on the separation of n-butanol from model aqueous solutions. Such research is undertaken mainly with the intention of facilitating biological butanol production, which is usually carried out through the ABE fermentation process. So far, various sorts of RTILs have been tested for this purpose while mostly ternary liquid-liquid systems have been investigated. The industrial design of liquid-liquid extraction requires prior knowledge of the state of thermodynamic equilibrium and its relation to the process parameters. Such knowledge can be obtained by performing a series of extraction experiments and employing a certain mathematical model to approximate the equilibrium. There are at least a few models available but this paper concentrates primarily on the NRTL equation, which has proven to be one of the most accurate tools for correlating experimental equilibrium data. Thus, all the presented studies have been selected based on the accepted modeling method. The reader is also shown how the NRTL equation can be used to model liquid-liquid systems containing more than three components as it has been the authors’ recent area of expertise.

scholarly journals Tantalum and Niobium Selective Extraction by Alkyl-Acetophenone

Metals ◽  
2018 ◽  
Vol 8 (9) ◽  
pp. 654 ◽  
Author(s):  
Moussa Toure ◽  
Guilhem Arrachart ◽  
Jean Duhamet ◽  
Stephane Pellet-Rostaing
Keyword(s):  
Extraction Efficiency ◽  
Methyl Isobutyl Ketone ◽  
Selective Extraction ◽  
Extraction Process ◽  
Liquid Extraction ◽  
Methyl Isobutyl ◽  
Isobutyl Ketone ◽  
Waste Solution ◽  
Liquid Liquid Extraction ◽  
D Values

A study has been carried out on Ta and Nb recovery by a liquid-liquid extraction process using 4-methylacetophenone (4-MAcPh) as the organic phase. The 4-MAcPh was compared to methyl isobutyl ketone (MIBK) with respect to extraction efficiencies (D values) at different concentrations of H2SO4 in the aqueous phase. The results showed a similar extraction of Nb for both solvents. However, for Ta, extraction efficiency is increased by a factor of 1.3 for 4-MAcPh. In addition, the MIBK solubilized completely after 6 mol∙L−1 of H2SO4 against only a loss of 0.14–4% for 4-MAcPh between 6 and 9 mol∙L−1 of H2SO4. The potential of 4-MAcPh has also been studied to selectively recover Ta from a model capacitor waste solution. The results showed a selectivity for Ta in the presence of impurities such as Ag, Fe, Ni and Mn. The 4-MAcPh also presents the advantage of having physicochemical properties adapted to its use in liquid-liquid extraction technologies such as mixer-settlers.

scholarly journals Solvent Extraction And Spectrophotomteric Determination Of Cu(Ii) With Dicyclohexyl - 18- Crown-6

2013 ◽  
Vol 10 (3) ◽  
pp. 997-1004
Author(s):  
Baghdad Science Journal
Keyword(s):  
Aqueous Solution ◽  
Solvent Extraction ◽  
Correlation Coefficient ◽  
Extraction Efficiency ◽  
Molar Absorptivity ◽  
Liquid Extraction ◽  
Liquid Liquid Extraction ◽  
Coloured Complex

Liquid-Liquid Extraction of Cu(II) ion in aqueous solution by dicyclohexyl-18-crown-6 as extractant in dichloroethane was studied .The extraction efficiency was investigated by a spectrophometric method. The reagent form a coloured complex which has been a quantitatively extracted at pH 6.3. The method obeys Beer`s law over range from (2.5-22.5) ppm with the correlation coefficient of 0.9989. The molar absorptivity the stoichiometry of extracted complex is found to be 1:2. the proposed method is very sensitive and selective.

scholarly journals Tantalum and Niobium Selective Extraction by Alkyl-Acetophenone

2018 ◽  
Author(s):  
Moussa Toure ◽  
Guilhem Arrachart ◽  
Jean Duhamet ◽  
Stephane Pellet-Rostaing
Keyword(s):  
Physicochemical Properties ◽  
Aqueous Phase ◽  
Organic Phase ◽  
Extraction Efficiency ◽  
Selective Extraction ◽  
Extraction Process ◽  
Liquid Extraction ◽  
Waste Solution ◽  
Liquid Liquid Extraction ◽  
Kd Values

A study has been carried out on Ta and Nb recovery by liquid-liquid extraction process using 4-methylacetophenone (4-MAcPh) as organic phase. The 4-MAcPh was compared to methylisobutylketone (MIBK) with respect to extraction efficiencies (kD values) at different concentrations of H2SO4 in the aqueous phase. The results showed a similar extraction of Nb for both solvents. However, for Ta extraction efficiency is increased by a factor of 1.3 for 4-MAcPh. In addition, the MIBK solubilized completely after 6 mol L-1 of H2SO4 against only a loss of 0.14 to 4% for 4-MAcPh between 6 and 9 mol L-1 of H2SO4. The potential of 4-MAcPh has also been studied to selectively recover Ta from a model capacitor waste solution. The results showed a selectivity for Ta in the presence of impurities such as Fe, Ni, Mn. The 4-MAcPh also presents the advantage of having physicochemical properties adapted to its use in liquid-liquid extraction technologies such as mixer-settlers.

QUANTITATION OF CARVEDILOL OXIDATIVE METABOLITES IN HUMAN PLASMA USING LIQUID CHROMATOGRAPHY TANDEM MASS SPECTROMETRY

INDIAN DRUGS ◽  
2012 ◽  
Vol 49 (02) ◽  
pp. 37-44
Author(s):  
J Valarmathy ◽  
◽  
T. Sudha ◽  
K. L. Kumar ◽  
S. L Joshua
Keyword(s):  
Human Plasma ◽  
Room Temperature ◽  
Plasma Sample ◽  
Liquid Extraction ◽  
Liquid Liquid Extraction ◽  
Chromatography Tandem Mass Spectrometry ◽  
Oxidative Metabolites ◽  
Liquid Chromatography Tandem Mass ◽  
Assay Precision

A sensitive and efficient method was developed for the determination of carvedilol and its metabolite in human plasma by LC-MS/MS. Plasma samples were hydrolysed with beta-glucuronidase and the target compounds were extracted with liquid liquid extraction using diethyl ether in dichloro methane as solvent. The extracts were completely derivatized and analysed by LC-MS/MS. The linearity of the assay ranges from 0.250 ng/mL to 200.0 ng/mL for carvedilol and from 0.500 ng/mL to 30.0 ng/mL for 4-hydroxy carvedilol. The absolute recovery of carvedilol and its metabolite added to blank plasma sample was 70.28 82.90%. The reproducibility was from 0.96 to 8.28 for the intraday assay and from 1.65 to 6.09 for the interday assay precision. Repetitive thawing and freezing did not have an affect on metabolite through a minimum of three cycles. Thawed samples remaining in plasma for 4h before extraction were with 5% of theoretical value. Stability of the extracted samples on the auto sampler at room temperature was evaluated for 34 h and was observed to with in 12% of a fresh analytical sample for 4 hydroxy carvedilol. The proposed LC-MS/MS method was effective for the determination of carvedilol and it metabolite in human plasma.

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