scholarly journals Modulation of cardiac contractility in patients with chronic heart failure and atrial fibrillation

2020 ◽  
Vol 92 (9) ◽  
pp. 8-14
Author(s):  
T. M. Uskach ◽  
A. A. Safiullina ◽  
O. V. Sapel’nikov ◽  
V. A. Amanatova ◽  
O. A. Nikolaeva ◽  
...  
Keyword(s):  
Heart Failure ◽  
Atrial Fibrillation ◽  
Chronic Heart Failure ◽  
Cardiac Contractility ◽  
Functional Class ◽  
Life Questionnaire ◽  
Optimal Drug ◽  
6 Minute Walk Test

Aim.to evaluate the effectiveness of cardiac contractility modulation (MSS) in patients with chronic heart failure (CHF) and atrial fibrillation (AF). Materials and methods.The following studies were performed in 40 patients with CHF and AF before implantation of the MSS device and after 2 and 6 months of follow-up: 12-channel ECG, transthoracic EchoCG, 6-minute walk test, determination of the level of Pro-natriuretic N-terminal peptide (NT-proBNP), daily ECG monitoring, and a questionnaire based on the Minnesota quality of life questionnaire for patients with CHF (MHFLQ). All patients received long-term optimal drug therapy for CHF before surgery. Results.The results obtained indicate a statistically significant positive effect of the use of MSS in patients with CHF and AF on LV FV, the functional class of CHF, and levels of NT-proBNP regardless of the etiology of CHF. Conclusion.The use of MSS may be promising for the treatment of heart failure in patients with CHF and AF.

scholarly journals Implantation of a cardiac contractility modulator in chronic heart failure and atrial fibrillation: results of a 6-month follow-up of one hundred patients

2021 ◽  
Vol 23 (1) ◽  
pp. 30-37
Author(s):  
T. M. Uskach ◽  
O. V. Sapelnikov ◽  
A. A. Safiullina ◽  
I. R. Grishin ◽  
V. A. Amanatova ◽  
...  
Keyword(s):  
Heart Failure ◽  
Atrial Fibrillation ◽  
Chronic Heart Failure ◽  
Cardiac Contractility ◽  
Treatment Method ◽  
Functional Class ◽  
Life Questionnaire ◽  
Medication Therapy ◽  
6 Minute Walk Test

Aim: to study the effect of cardiac contractility modulation (CCM) in patients with chronic heart failure (CHF) and atrial fibrillation (AF). Materials and methods. In a group of 100 patients with CHF and AF, the following studies were performed before implantation of the CCM and after 6 months of follow-up: 12-channel ECG, transthoracic Echocardiography, 6-minute walk test, determination of the level of pro-natriuretic N-terminal peptide (NT-proBNP), and a questionnaire based on the Minnesota quality of life questionnaire for patients with CHF (MHFLQ). All patients received long-term optimal medication therapy for CHF before surgery. Results. The results show a positive effect of the use of MCC in patients with CHF and AF on reverse LV remodeling, functional class of CHF, and levels of NT-pro-BNP regardless of the form of AF. Conclusion. The use of MCC may be a promising treatment method in addition to optimal medication therapy in patients with CHF and AF.

scholarly journals Dynamics of Holter electrocardiogram monitoring in patients with chronic heart failure and atrial fibrillation on the background of cardiac contractility modulation

2021 ◽  
Vol 93 (9) ◽  
pp. 1044-1051
Author(s):  
Alfiya A. Safiullina ◽  
Tatiana M. Uskach ◽  
Yulduz S. Sharapova ◽  
Anatolii G. Kochetov ◽  
Oleg V. Sapelnikov ◽  
...  
Keyword(s):  
Heart Failure ◽  
Atrial Fibrillation ◽  
Chronic Heart Failure ◽  
Cardiac Arrhythmias ◽  
Cardiac Contractility ◽  
Reverse Remodeling ◽  
Ecg Monitoring ◽  
Cardiac Contractility Modulation ◽  
Optimal Drug

Aim. To evaluate the dynamics of cardiac arrhythmias on the background of cardiac contractility modulation (MCC) in patients with chronic heart failure (CHF) and various forms of atrial fibrillation (AF) on the basis of daily electrocardiogram (ECG) monitoring. Materials and methods. In 100 patients with CHF and AF, the following studies were performed before implantation of the MCC device and after 12 months of follow-up: 12-channel ECG with an estimate of the width of the QRS complex, transthoracic echocardiography (EchoCG), and Holter ECG monitoring. All patients received long-term optimal drug therapy for CHF before surgery. Results. The results obtained indicate that there is no effect of MCC on the development and progression of ventricular arrhythmias in patients with CHF and AF during the year of follow-up, both extrasystole and tachyarrhythmias, regardless of the etiology and LVEF (less than 35% or more than 35%), and a decrease in the frequency of AF paroxysms in patients with CHF during treatment. These results are due to the reverse remodeling of the LV myocardium under the influence of the MCC device. Conclusion. The use of MСС in patients with CHF and AF is a safe method of therapy that does not induce cardiac arrhythmias, including ventricular extrasystole. Large-scale comparative studies are required to evaluate these results.

scholarly journals Role of comorbidities in heart failure prognosis Part I: Anaemia, iron deficiency, diabetes, atrial fibrillation

2020 ◽  
Vol 27 (2_suppl) ◽  
pp. 27-34
Author(s):  
Stefania Paolillo ◽  
Angela B Scardovi ◽  
Jeness Campodonico
Keyword(s):  
Diabetes Mellitus ◽  
Heart Failure ◽  
Atrial Fibrillation ◽  
Chronic Heart Failure ◽  
Iron Deficiency ◽  
Prognostic Impact ◽  
Heart Failure Patients ◽  
Cardiovascular Comorbidities ◽  
Long Term Prognosis

Cardiovascular and non-cardiovascular comorbidities are frequently observed in heart failure patients, complicating the therapeutic management and leading to poor prognosis. The prompt recognition of associated comorbid conditions is of great importance to optimize the clinical management, the follow-up, and the treatment of patients affected by chronic heart failure. Anaemia and iron deficiency are commonly reported in all heart failure forms, have a multifactorial aetiology and are responsible for reduced exercise tolerance, impaired quality of life, and poor long-term prognosis. Diabetes mellitus is highly prevalent in heart failure and a poor glycaemic control is associated with worst outcome. Two specific heart failure forms are usually observed in diabetic patients: an ischaemic cardiomyopathy or a typical diabetic cardiomyopathy. The implementation of use of sodium-glucose cotransporter-2 inhibitors will much improve in the near future the long-term prognosis of patients affected by heart failure and diabetes. Among cardiovascular comorbidities, atrial fibrillation is the most common arrhythmic disease of heart failure patients and it is still not clear whether its presence should be considered as a prognostic indicator or as a marker of advanced disease. The aim of the present review was to explore the clinical and prognostic impact of anaemia and iron deficiency, diabetes mellitus, and atrial fibrillation in patients affected by chronic heart failure.

scholarly journals Prognostic relevance of atrial fibrillation in patients with chronic heart failure on long-term treatment with beta-blockers: results from COMET

2005 ◽  
Vol 26 (13) ◽  
pp. 1303-1308 ◽  
Author(s):  
Karl Swedberg ◽  
Lars G. Olsson ◽  
Andrew Charlesworth ◽  
John Cleland ◽  
Peter Hanrath ◽  
...  
Keyword(s):  
Heart Failure ◽  
Atrial Fibrillation ◽  
Chronic Heart Failure ◽  
Beta Blockers ◽  
Term Treatment ◽  
Prognostic Relevance ◽  
Long Term Treatment

scholarly journals Evaluation of the influence of the therapy with fosinopril and zofenopril on the regulatory-adaptive status of patients with diastolic chronic heart failure

2019 ◽  
Vol 10 (4) ◽  
pp. 23-28
Author(s):  
Svetlana N. Nedvetskaya ◽  
Vitalii G. Tregubov ◽  
Iosif Z. Shubitidze ◽  
Vladimir M. Pokrovskiy
Keyword(s):  
Heart Failure ◽  
New York ◽  
Chronic Heart Failure ◽  
Subjective Evaluation ◽  
Heart Association ◽  
Functional Class ◽  
New York Heart Association

Aim. Еvaluate the influence of combination therapy with fosinopril or zofenopril on the regulatory-adaptive status (RAS) of patients with diastolic chronic heart failure (CHF). Material and methods. The study includes 80 patients with CHF I-II functional class according to the classification of the New York heart Association with left ventricle ejection fraction ≥50% because of hypertensive disease (HD) of III stage, who were randomized into two groups for treatment with fosinopril (14.7±4.2 mg/day, n=40) or zofenopril (22.5±7.5 mg/day, n=40). As part of combination pharmacotherapy, patients were included nebivolol (7.1±2.0 mg/day and 6.8±1.9 mg/day), in the presence of indications, atorvastatin and acetylsalicylic acid in the intestinal shell were prescribed. Initially and after six months, the following was done: a quantitative evaluation of the RAS (by cardio-respiratory synchronism test), echocardiography, tredmil-test, six-minute walking test, determination of the N-terminal precursor of the natriuretic brain peptide level in blood plasma and subjective evaluation of quality of life. Results. Therapy, using fosinopril, in comparison with zofenopril, more improved RAS (by 66.5%, p

scholarly journals CLINICAL ASPECTS OF TREATMENT OF PATIENTS WITH LONG-PERSISTENT FORMOF ATRIAL FIBRILLATION AND DECOMPENSATED CHRONIC HEART FAILURE, USING A METHODOF RADIOFREQUENCY CATHETER ABLATION AND CARDIAC RESYNCHRONIZATION THERAPY

2013 ◽  
Vol 4 (3) ◽  
pp. 49-55
Author(s):  
A A Kocharyan ◽  
E G Zhelyakov ◽  
R R Guseynova ◽  
A V Konev ◽  
A V Ardashev
Keyword(s):  
Heart Failure ◽  
Atrial Fibrillation ◽  
Chronic Heart Failure ◽  
Combined Treatment ◽  
Persistent Atrial Fibrillation ◽  
Functional Class ◽  
Cardiac Resynchronization ◽  
Clinical Aspects ◽  
Resynchronization Therapy ◽  
Dynamic Observation

The article describes a clinical case of a 64-years patient with long-lasting persistent atrial fibrillation with the progressive course of chronic heart failure, which successfully treated with CRT setting and RFA of AFib. Dynamic observation of the patient during 12 months confirmed the success of combined treatment – absence of arrhythmia recurrences and decreasing of NYHA heart failure functional class.

scholarly journals New approaches to assessing the contractile function of the left ventricular in patients with heart failure on the background of modulation of cardiac contractility.

2020 ◽  
pp. 4-13
Author(s):  
А.А. Сафиуллина ◽  
Т.М. Ускач ◽  
М.А. Саидова ◽  
С.В. Добровольская ◽  
С.Н. Терещенко
Keyword(s):  
Heart Failure ◽  
Atrial Fibrillation ◽  
Chronic Heart Failure ◽  
Left Ventricle ◽  
Left Atrium ◽  
Contractile Function ◽  
Cardiac Contractility ◽  
Left Ventricular ◽  
Reverse Remodeling ◽  
Heart Contractility

Обзор посвящен роли современной трансторакальной эхокардиографии и новому способу неинвазивной оценки сократительной функции левого желудочка – исследованию эффективности миокардиальной работы у пациентов хронической сердечной недостаточностью. Освещаются актуальные аспекты ремоделирования левого желудочка и левого предсердия у данной категории пациентов. Обсуждается роль и важность метода спекл-трекинг эхокардиографии в оценке механической функции левого предсердия. Представлены сведения об относительно новом электрофизиологическом методе лечения - модуляции сердечной сократимости у пациентов с хронической сердечной недостаточностью, как с фибрилляцией предсердий, так и без нее. Анализируются результаты обратного ремоделирования левого желудочка по данным эхокардиографических параметров основных исследований, посвященных модуляции сердечной сократимости. В статье оцениваются перспективы применения метода оценки эффективности миокардиальной работы левого желудочка как инструмента возможного обратного ремоделирования у пациентов с хронической сердечной недостаточностью и фибрилляцией предсердий на фоне модуляции сердечной сократимости The review is devoted to the role of modern transthoracic echocardiography and a new method of non-invasive assessment of left ventricular contractile function-the study of the effectiveness of myocardial work in patients with chronic heart failure. The current aspects of left ventricle and left atrium remodeling in this category of patients are highlighted. The role and importance of speckle-tracking echocardiography in evaluating the mechanical function of the left atrium is discussed. Information is provided about a relatively new electrophysiological method of treatment-modulation of heart contractility in patients with chronic heart failure, both with and without atrial fibrillation. The results of reverse remodeling of the left ventricle are analyzed according to the echocardiographic parameters of the main studies devoted to the modulation of heart contractility. The article assesses the prospects for using the method of evaluating the effectiveness of left ventricular myocardial function as a tool for possible reverse remodeling in patients with chronic heart failure and atrial fibrillation against the background of heart contractility modulation

scholarly journals Effect of Preoperative Atrial Fibrillation on Patients with Chronic Heart Failure Who Undergo Long-Term Continuous-Flow LVAD Implantation

ASAIO Journal ◽  
2018 ◽  
Vol 64 (5) ◽  
pp. 594-600 ◽  
Author(s):  
Chitaru Kurihara ◽  
Andre Critsinelis ◽  
Masashi Kawabori ◽  
Tadahisa Sugiura ◽  
Andrew B. Civitello ◽  
...  
Keyword(s):  
Heart Failure ◽  
Atrial Fibrillation ◽  
Chronic Heart Failure ◽  
Continuous Flow
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