scholarly journals A study of correlation between thyroid disorders and menstrual disorders in reproductive age group

2020 ◽  
Vol 11 (3) ◽  
pp. 3183-3190
Author(s):  
Moulika Shirish Shah ◽  
Patange R. P

Present study to evaluate and detect thyroid dysfunction and its correlation in patients with a menstrual disorder in the reproductive age group. Research objectives are to study the prevalence of thyroid disorders in relation to menstrual disorders and study the correlation between menstrual irregularities and thyroid dysfunction. Precise assessments of thyroid hormones in serum become achievable easily and accurately with the introduction of new hormographical research techniques. Hypothyroidism diagnosis is advantageous because it typically relieves the patient of all symptoms. Therefore, the assessment of thyroid activity forms an essential component for the evaluation of a female with menorrhagia or otherwise menstrual irregularities. The individuals are rescued from repeated curettage from hysterectomy by early diagnosis of hypothyroidism Objectively measured menstrual blood losses were 35 ml per menstrual cycle (patients in the age group exposures.

Author(s):  
Anupma Kumari ◽  
Renu Rohatgi ◽  
Amrita Singh

Background: Thyroid disorders specifically the hypothyroidism has been associated with menstrual disturbances in women of reproductive age group. The objective of this study was to estimate the prevalence of thyroid dysfunction and its correlation with menstrual disorders in women of reproductive age group.Methods: A hospital based prospective analytical study was carried out in the department of Obstetrics and Gynaecology of Nalanda Medical College and Hospital, Patna from March 2017 to March 2018. 56 women of reproductive age group between 18 to 45 years presenting with menstrual disorders (like menorrhagia, oligo/hypomenorrhea, polymenorrhea, metrorrhagia, and amenorrhea) were recruited in this study. Thyroid function test was done in all patients. Statistical analysis done.Results: Maximum number of patients were seen in the age group of 31-40 years. Most common menstrual complain was menorrhagia (46.42%) followed by hypo/oligomenorrhoea (17.86%). In patients with menstrual disorders, 41.07 % had thyroid disorders in which subclinical hypothyroidism was prevalent in 17.86%, overt hypothyroidism in 12.5%, and overt hyperthyroidism in 5.35% of the women. Menorrhagia was the commonest menstrual disorder (52.94%) seen in hypothyroid patients followed by polymenorrhoea. A high degree positive correlation was observed between thyroid dysfunction and menstrual disorder (Pearson correlation coefficient, r=0.93).Conclusions: Our study concluded that thyroid dysfunction should be considered as an important etiological factor for menstrual irregularity. Thus, thyroid function tests should be performed in all patients with menstrual irregularities to avoid unnecessary interventions like curettage and hysterectomy.


2021 ◽  
pp. 15-16
Author(s):  
Kumari Ragini ◽  
Kumar Sourav ◽  
Lata Shukla Diwedi ◽  
Debarshi Jana

Introduction: Abnormal uterine bleeding (AUB) is a common disorder occurring in reproductive age group females. It can be understood as bleeding that occurs from the uterus outside the normal parameters and there is no structural defects in the genital tract. One of the most common association with AUB is thyroid dysfunctions. Hence this study aimed to see the incidence of thyroid related disorders in AUB and also to assess the menstrual pattern. Material and Methods: 100 women suffering from AUB who presented to OPD of Obstetrics and Gynecology department of Anugrah Narayan Magadh Medical College and Hospital, Gaya, Bihar were recruited in the study. All females in 19 to 45 years of age group with abnormal uterine bleeding were included excluding those with previously known thyroid disorder, abortion history within 3 months etc. Thyroid function tests were done in all along with ultrasonography of pelvis region. Statistical analysis done. Results: The bleeding abnormality that was found in the most of the women was heavy menstrual bleeding. Women who presented with thyroid dysfunction were 33%. 23% had subclinical hypothyroidism, 6% had hypothyroidism and 4% had hyperthyroidism. Conclusion: Abnormal Uterine Bleeding has strong association with thyroid disorders. Most common type of disorder is subclinical hypothyroidism. Thus all patient of AUB must be evaluated for thyroid dysfunction


Author(s):  
Dinesh Gurjar ◽  
Purnima Pachori ◽  
Sandhya Chaudhary ◽  
Dharmendra Singh

Background: Hypothyroidism and Hyperthyroidism leads to menstrual irregularities. Females with thyroid gland abnormality have chances of reproductive abnormalities ranging from abnormal sexual development, menstrual irregularities, infertility and premature menopause. The objectives were to study the association between thyroid dysfunction and AUB in the reproductive age group (18-45 years), To study the thyroid abnormalities in different types of AUB in the reproductive age group, to establish if screening for thyroid abnormalities is justified using T3, T4 and TSH.Methods: This cross-sectional study conducted among 250 women with ‘abnormal uterine bleeding’ (AUB). Inclusion criteria for participants were females in the age group of 18-45 years, females presenting with abnormal uterine bleeding, with thyroid dysfunction, females who do not have signs of demonstrable pelvic pathologyincluding PID.Results: Majority of the patients belonged to the age group of 24 - 32 years i.e.56.8%, 9.2% cases were nullipara, 44.0% cases have menorrhagia, 32.2% have oliogomennorrhea, 19.6% have amenorrhea. Around 3.6% had Thyromegaly, 12.4% have weight gain in hypothyroidism, 28.4% have fatigue in hyperthyroidism, 6.8% cases have higher T4 level, 18.0% cases have higher TSH level.Conclusions: The risk of progression to overt hypothyroidism (about 5% per year) in patients with subclinical disease and the cost-benefit ratio also emphasises the need for selective screening. Early detection of subclinical disease by selective screening facilitates appropriate therapy early in the course of the disease.


Author(s):  
Aditi Rai ◽  
Sapna Raina

Background: Abnormal uterine bleeding (AUB) is one of the most frequent presentation to gynecology OPD. AUB is a common but complicated clinical presentation and occurs in 15-20% of women between menarche to menopause and significantly affects the women’s health. Thyroid disorders are more common in women than in men and cause abnormal sexual development, menstrual irregularity, infertility and premature menopause. Objective of this study was to estimate the prevalence of thyroid disorders in women in reproductive age group with AUB.Methods: A hospital based prospective cross sectional observational study was carried out in department of obstetrics and gynecology, Mazumdar-Shaw Cancer and Medical Center and Narayana Hrudayalaya Hospital at Narayana Health City, Bangalore with abnormal uterine bleeding during the period of 2 years (December 2015 to November 2017), total 153 patients were included in the study. All women with AUB in reproductive age group were included. Diagnosed cases of ovarian cyst, uterine fibroid, polyp, adenomyosis, endometriosis and malignant (endometrial and cervical) tumors were excluded. Women who are on drugs or hormone therapy (for past 3 months. IUCD users/oral contraceptives pill user. Patients with known case of thyroid disorder, carcinoma thyroid patients with history of coagulation disorder, liver disorder, renal disorder, tuberculosis.Results: A total N=115 (75.2%) of patients who took part in this study had euthyroid status. The estimated prevalence of thyroid dysfunction was 24.9%. Out of which n=22 (14.4%) had subclinical hypothyroidism, n=14 (9.2%) had overt hypothyroidism, n=2 (1.3%) had hyperthyroidism. The most common thyroid dysfunction amongst the study group was noted to be subclinical hypothyroidism (14.4%).Conclusions: There is a high prevalence of thyroid disorders in cases which are clinically diagnosed as AUB. TSH is most sensitive test in detecting thyroid dysfunction. Subclinical cases need to be treated. Hence thyroid function evaluation should be made mandatory in cases of AUB to detect thyroid dysfunction.


Author(s):  
Kavitha Marimuthu ◽  
Malarvizhi Loganathan

Background: Abnormal Uterine Bleeding is a common complaint encountered in Gynaecology OPD. It occurs in 9-14% of women from Menarche to Menopause affecting quality of life imposing financial burden. Thyroid dysfunction causes broad spectrum of reproductive disorders from abnormal sexual development, menstrual irregularities, infertility and premature menopause. Thyroid disorders are 10 times more common in women and increased prevalence of thyroid disorders in women is possibly due to auto immune nature.Methods: This Prospective study population consisted of 250 women attending the Gynaecology Outpatient Clinic, in Government Dharmapuri Medical College Hospital, with complaints of bleeding problems during menstruation in the age group of 18 to 45 years.Results: Of 250 cases of abnormal uterine bleeding in reproductive age group attending the outpatient department about 68 cases have thyroid dysfunction. The common thyroid dysfunction in our study was hypothyroidism which comprises about 15.6% similarly other thyroid dysfunction are hyperthyroidism in 7.2% and subclinical hypothyroidism in 3.2% and subclinical hyperthyroidism 1.2%.Conclusions: It brings into focus the increased incidence of hypothyroidism among women with menorrhagia and amenorrhea. And increased incidence of hyperthyroidism in women with oligomenorrhea. Early detection by selective screening and specific pharmacotherapy for subclinical thyroid disease early in the course of the disease will prove to be a superior alternative to surgical treatments like hysterectomy.


Author(s):  
Priyanka Yadav ◽  
Geetika Arora

Background: Menstrual disorders are a common problem in reproductive age females. These disorders may cause significant anxiety for patients and their families. Thyroid dysfunction is one of the common cause of menstrual irregularities. Aim of the study was to determine the prevalence of hypothyroidism in reproductive age group women (15-45years), describe its various modes of clinical presentation and to assess the menstrual pattern in women with hypothyroidism.Methods: Prospective observational hospital based study during a period of 6 months (January 2020 to June 2020) on patients presenting in OPD in department of obstetrics and gynaecology, SGT medical college, hospital and research institute, Budhera, Gurgaon.Results: Prevalence of hypothyroidism was found to be 52.6% (190 out of total 338 patients) and it increased with increasing age group. 213 patients out of total came with complains of menstrual irregularities. 49.2% with normal menstrual cycle had hypothyroidism while 60.4% presenting with irregular heavy menstrual bleeding had hypothyroidism, p value being 0.019 which was statistically significant.Conclusions: Menstrual irregularities increase with severity of hypothyroidism. So screening for thyroid dysfunction should be included in management plan of menstrual disturbances.


2021 ◽  
pp. 9-10
Author(s):  
Madhuri Rani ◽  
Kumudini Jha ◽  
Debarshi Jana

Background:. AUB is any abnormal uterine bleeding in the absence of any palpable pelvic pathology and demonstrable extra genital causes. AUB is responsible for 10% of gynaecological complaints.Hypothyroidism and Hyperthyroidism leads to menstrual irregularities. Females with thyroid gland abnormality have chances of reproductive abnormalities ranging from abnormal sexual development, menstrual irregularities, infertility and premature menopause.The objective of this study is to estimate the prevalence of thyroid disorders in women with abnormal uterine bleeding and to assess the menstrul pattern in women with thyroid disorder Methods: The present study was conducted in the Department of Obstetrics and Gynecology, Darbhanga Medical College and Hospital, Laheriasarai, Bihar. Total100 women of reproductive age group between 15-45 years women with abnormal bleeding were studied.Quantitative determination of T3, T4, and TSH by CLIAestimated in autoanlyser. Results: About 100 women participated in the study in which Most of the subjects belong to 26-30 years of age group(30%)followed by20-25 yrs(22%).13% in age group36-40.menorrhagia was the most common presenting symptom(66%)followed by oligomenorrhoea(21%) Thyroid disorders were prevalent in 22%.hypothyroid in 20%and hyperthyroidism in 2%.Majority had menorrhagia 66%followed by oligomenorrhea21%.among thyroid dysfunction 63.3%had menorrhagia and 36.36% had oligomenorrhea. Conclusions: So, biochemical evaluation of thyroid functioning should be made mandatory in all provisionally diagnosed cases of AUB to detect thyroid dysfunction.


2020 ◽  
Vol 11 (6) ◽  
pp. 102-104
Author(s):  
Bindya R ◽  
Maya Balakrishnan ◽  
Giby Thomas

The polycystic ovarian syndrome is an extremely prevalent heterogeneous disorder affecting women in the reproductive age group. Symptoms may include menstrual irregularities, hyperandrogenism, or another endocrine dysfunction. Women with PCOS are more likely to be obese and are evident by their elevated BMIs and Waist: Hip ratios. These ratios reflect an android or central pattern of obesity which are the risk factors for cardiovascular disease one of the long-term consequences of PCOS. Obesity or sthoulya is a Santharpanajanya roga. Athisthoulyam is also mentioned under Ashtou ninditha purushas. An exact correlation of PCOS cannot be found in our classics; rather most clinical features are seen scattered among the symptoms and diseases mentioned in the context of Streeroga. Main menstrual irregularities seen in PCO women are oligomenorrhoea, amenorrhoea, and DUB which are found in the context of Artava Vyapat like Artavakshaya, Nashtartava, and Asrigdhara respectively. Anovulation resulting in amenorrhoea can be compared with Vandya yonivyapat and Pushpagni Jataharini.


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