scholarly journals Review of phytochemistry, biological activities and therapeutic potential of Cleistochlamys kirkii

2020 ◽  
Vol 11 (4) ◽  
pp. 5596-5602
Author(s):  
Alfred Maroyi
Keyword(s):  
Therapeutic Potential ◽  
Biological Activities ◽  
Central Africa ◽  
Indole Alkaloid ◽  
Pharmaceutical Products ◽  
Future Research ◽  
Pharmacological Properties ◽  
Scientific Publications ◽  
Medicinal Uses

Cleistochlamys kirkii (Benth.) Oliv is a shrub or small tree widely used as a traditional medicine in the east and central Africa. Cleistochlamys kirkii is indigenous to Malawi, Mozambique, Tanzania, Zambia and Zimbabwe. This study is aimed at evaluating the phytochemistry, biological activities and therapeutic potential of C. kirkii. Results of the current study are based on data derived from several online databases such as Scopus, Google Scholar, PubMed and Science Direct, and pre-electronic sources such as scientific publications, books, dissertations, book chapters and journal articles. This study revealed that the leaf and root infusion, maceration and decoction of C. kirkii are mainly used as traditional medicines for haemorrhoid wounds, rheumatism and tuberculosis. Phytochemical compounds identified from the species include α,β-unsaturated lactone, acetogenin, benzyl benzoate derivatives, c-benzylated flavanone, heptanolide, an indole alkaloid, phenolics, polyoxygenated cyclohexene and derivatives, sesquiterpene and tetracyclic triterpenes. In vitro studies have confirmed the biological activities of C. kirkii crude extracts and compounds isolated from the species which include antibacterial, antifungal, antiplasmodial and cytotoxicity. Documentation of the medicinal uses, phytochemistry and pharmacological properties of C. kirkii is essential as this information provides baseline data required for future research and development of health-promoting and pharmaceutical products. Cleistochlamys kirkii should be subjected to detailed ethnopharmacological and toxicological evaluations aimed at correlating its medicinal uses with its phytochemistry and pharmacological properties.

scholarly journals Evaluation of medicinal uses, phytochemistry and pharmacological properties of Bersama lucens (Hochst.) Szyszyl.

2020 ◽  
Vol 11 (4) ◽  
pp. 5855-5859
Author(s):  
Alfred Maroyi
Keyword(s):  
Biological Activities ◽  
Pharmaceutical Products ◽  
In Vivo Studies ◽  
Future Research ◽  
Pharmacological Properties ◽  
Scientific Publications ◽  
Medicinal Uses ◽  
Sexually Transmitted ◽  
Phytochemical Compounds

Bersama lucens (Hochst.) Szyszyl is a shrub or small tree with its different parts used traditionally to treat various diseases. Bersama lucens has been recorded in Eswatini, Mozambique and South Africa. The main aim of this review is to provide an overview and critical analysis of the medicinal uses, phytochemistry and biological activities of B. lucens. The information presented in this study was gathered using various databases such as PubMed, Taylor and Francis imprints, Springer, NCBI, Google scholar and Science direct, and review of books, journal articles and other scientific publications kept in the University library. The bark and root infusion or decoction of B. lucens are mainly used as a blood purifier, lice repellent and protective charm, and traditional medicine for stomach problems, leprosy, stroke, sexually transmitted infections, headache, infertility, nervous disorders, impotence and menstrual pain. The biological activities exhibited by B. lucens extracts include antibacterial, antifungal and anti-inflammatory activities. Documentation of the medicinal uses, phytochemistry and pharmacological properties of B. lucens is vital as this information provides baseline data required for future research and development of health-promoting and pharmaceutical products. Future research should focus on detailed phytochemical, pharmacological and toxicological screening, in vivo studies and clinical trials involving the crude extracts and phytochemical compounds isolated from the species.

scholarly journals Cussonia natalensis Sond. and C. zuluensis Strey (Araliaceae): A comparative analysis of their medicinal uses and pharmacological properties

2020 ◽  
Vol 11 (4) ◽  
pp. 6089-6094
Author(s):  
Alfred Maroyi
Keyword(s):  
Pharmaceutical Products ◽  
Future Research ◽  
Pharmacological Properties ◽  
Leaf Extracts ◽  
Scientific Publications ◽  
Pentacyclic Triterpene ◽  
Medicinal Uses ◽  
Toxicological Studies ◽  
History Of ◽  
Cytotoxicity Activities

Cussonia natalensis Sond. and C. zuluensis Strey have a long history of medicinal use in southern Africa. The aim of this study was to review the medicinal uses and pharmacological properties of the two species. Results of this study are based on data derived from several online databases such as Scopus, Google Scholar, PubMed and Science Direct, and pre-electronic sources such as scientific publications, books, dissertations, book chapters and journal articles. The bark, fruits and roots of C. natalensis and C. zuluensis are used as emetic, purgative and protective charm, and traditional medicine for diarrhoea, fever, stomach ache and swellings. This study showed that pentacyclic triterpene acids, cardiac glycosides, flavonoids, polyphenols, saponins and steroids have been identified from the leaves, roots and twigs of the species. The leaf extracts and compounds isolated from C. natalensis and C. zuluensis exhibited antibacterial, antifungal, antimalarial, antiprotozoal and cytotoxicity activities. Documentation of the medicinal uses, phytochemistry and pharmacological properties of C. natalensis and C. zuluensis is important as this information provides baseline data required for future research and development of health-promoting and pharmaceutical products. There is need for extensive phytochemical, pharmacological and toxicological studies of crude extracts of C. natalensis and C. zuluensis to establish the safety profiles of different preparations of the two species.

scholarly journals A synthesis and review of medicinal uses, phytochemistry and biological activities of Markhamia zanzibarica

2020 ◽  
Vol 11 (4) ◽  
pp. 5985-5993
Author(s):  
Alfred Maroyi
Keyword(s):  
Respiratory Infections ◽  
Biological Activities ◽  
Clinical Effectiveness ◽  
Pharmaceutical Products ◽  
Future Research ◽  
Extensive Literature ◽  
Medicinal Uses ◽  
In Vivo Experiments

Markhamia zanzibarica (Bojer ex DC.) K. Schum.has been used in herbal medicine in tropical Africa since ancient times. Markhamia zanzibarica is indigenous to central, eastern and southern Africa. This extensive literature review synthesizes the information currently available on the medicinal uses, phytochemistry and biological activities of M. zanzibarica. The University library and electronic search engines Google Scholar, Scopus, Web of Science, ScienceDirect and PubMed were searched for pertinent information on the medicinal uses, phytochemistry and biological activities of M. zanzibarica. Traditionally, the species has been used as anthelmintic, and traditional medicine for backache, female reproductive problems, sexually transmitted infections, respiratory infections and gastro-intestinal problems. In vitro studies have confirmed the biological activities of M. zanzibarica which include antibacterial, antimycobacterial, antioxidant and cytotoxicity. Various phytochemicals such as alkaloids, anthraquinones, fatty acids, flavonoids, glycosides, phenolics, saponins, sterols, tannins and triterpenes have been isolated from M. zanzibarica. Documentation of the medicinal uses, phytochemistry and pharmacological properties of M. zanzibarica is essential as this information provides baseline data required for future research and development of health-promoting and pharmaceutical products. However, further pharmacological studies including phytochemical, toxicological, in vitro and in vivo experiments are needed to provide evidence for the clinical effectiveness of remedies prepared from the species.

scholarly journals Cissampelos capensis L.f. (Menispermaceae): Review of its medicinal uses, phytochemical and pharmacological properties

2020 ◽  
Vol 11 (4) ◽  
pp. 5948-5955
Author(s):  
Alfred Maroyi
Keyword(s):  
Skin Diseases ◽  
Pharmaceutical Products ◽  
Future Research ◽  
Pharmacological Properties ◽  
Scientific Publications ◽  
Medicinal Uses ◽  
Sexually Transmitted ◽  
Traditional Medicines ◽  
Gastrointestinal Problems ◽  
Cytotoxicity Activities

Cissampelos capensis L.f. is a perennial climber widely used as a traditional medicine in South Africa. This study was aimed at providing a critical review of medicinal uses, phytochemical and pharmacological properties of C. capensis. Documented information on the pharmacological properties, phytochemistry and medicinal uses of C. capensis was collected from several online sources such as Scopus, Google Scholar, PubMed and Science Direct, and pre-electronic sources such as book chapters, books, journal articles and scientific publications obtained from the university library. This study revealed that leaf, rhizome and root infusions and decoctions of C. capensis are mainly used as a blood purifier, and traditional medicines for respiratory problems, ulcers, sores and wounds, skin and stomach cancers, snakebite, sexually transmitted infections, skin diseases, diabetes and gastrointestinal problems. Phytochemical compounds identified from the species include alkaloids, essential oils, flavonoids, phenolics, saponins and tannins. Pharmacological research revealed that C. capensis extracts and compounds isolated from the species have anthelmintic, antibacterial, antifungal, antidiabetic, antimalarial, hepatotoxicity, spermatozoa and cytotoxicity activities. Documentation of the medicinal uses, phytochemistry and pharmacological properties of C. capensis is vital as this information provides baseline data required for future research and development of health-promoting and pharmaceutical products. There is a need for extensive toxicological evaluations of crude extracts and compounds isolated from the species since C. capensis contains potentially toxic compounds.

scholarly journals A REVIEW OF BOTANY, THERAPEUTIC VALUE, PHYTOCHEMISTRY, AND PHARMACOLOGY OF CUSSONIA PANICULATA

2019 ◽  
pp. 1-6
Author(s):  
ALFRED MAROYI
Keyword(s):  
Herbal Medicine ◽  
Skin Diseases ◽  
Intestinal Parasites ◽  
Biological Activities ◽  
Triterpene Glycosides ◽  
Future Research ◽  
Steroidal Saponin ◽  
Scientific Publications ◽  
Triterpenoid Saponins ◽  
Medicinal Uses

Cussonia paniculata is a small tree widely used as herbal medicine throughout its distributional range in southern Africa. This study is aimed at providing a critical review of the botany, biological activities, phytochemistry, and medicinal uses of C. paniculata. Documented information on the botany, biological activities, medicinal uses, and phytochemistry of C. paniculata was collected from several online sources which included BMC, Scopus, SciFinder, Google Scholar, Science Direct, Elsevier, PubMed, and Web of Science. Additional information on the botany, biological activities, phytochemistry, and medicinal uses of C. paniculata was gathered from pre-electronic sources such as book chapters, books, journal articles, and scientific publications sourced from the University library. This study showed that the bark, fruits, leaves, roots, and stems of C. paniculata are used as emetic, immune booster, and herbal medicine for dysmenorrhea, intestinal parasites and worms, mental problems, boils, shingles and skin diseases, indigestion and stomach complaints, sores, and wounds. Phytochemical compounds identified from the leaves of C. paniculata include acetylated triterpene glycosides, unacetylated triterpene glycosides, flavonoid, steroidal saponin, and triterpenoid saponins. Pharmacological research revealed that C. paniculata extracts have analgesic, antibacterial, anticancer, anti-inflammatory, antiplasmodial, antiprotozoan, Aβ42 protein reduction, and cytotoxicity activities. Future research should focus on evaluating the phytochemical, pharmacological, and toxicological properties of C. paniculata crude extracts as well as compounds isolated from the species.

scholarly journals Gardenia ternifolia Schum. & Thonn. (Rubiaceae): Review of medicinal uses, phytochemistry and biological activities

2020 ◽  
Vol 11 (4) ◽  
pp. 5876-5885
Author(s):  
Alfred Maroyi
Keyword(s):  
Traditional Medicine ◽  
Democratic Republic Of Congo ◽  
Respiratory Infections ◽  
Biological Activities ◽  
Future Research ◽  
Tropical Africa ◽  
Scientific Publications ◽  
Medicinal Uses ◽  
Additional Information

Gardenia ternifolia Schum. & Thonn. is a shrub or small tree widely used as a traditional medicine throughout its distributional range in tropical Africa. Gardenia ternifolia is widespread in tropical Africa, extending from Senegal eastwards to Ethiopia and Kenya, through the Democratic Republic of Congo (DRC) southwards to Namibia, South Africa and Mozambique. This study was aimed at providing a critical review of the medicinal uses, phytochemistry and biological activities of G. ternifolia. Documented information on the medicinal uses, phytochemistry and biological activities of G. ternifolia was collected from several online sources which included Scopus, Google Scholar, PubMed and Science Direct. Additional information was gathered from pre-electronic sources such as book chapters, books, journal articles and scientific publications obtained from the university library. This study showed that the species is widely used as an aphrodisiac and protective charm, and traditional medicine for headache, migraine, respiratory infections, sore eyes, hypertension, diabetes, gastro-intestinal problems, erectile dysfunction, malaria, convulsions and epilepsy. Phytochemical compounds identified from the species include alkaloids, anthocyanins, coumarins, flavonoids, phenols, quinones, saponins, steroids, stereoisomeric neolignans, tannins and terpenoids. Pharmacological research revealed that G. ternifolia extracts and compounds isolated from the species have antibacterial, antiviral, anti-inflammatory, antileishmanial, antioxidant, antiplasmodial, antisickling, antitheilerial, hepatotoxicity, larvicidal and cytotoxicity activities. Future research on G. ternifolia should focus on detailed phytochemical evaluations, including toxicological, in vivo and clinical studies to corroborate the traditional medical applications of the species.

scholarly journals VALIDATION OF TRIBAL CLAIMS ON MORINGA OLEIFERA LAM. USING PHYTOCHEMICAL ANALYSIS

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Getsial Sabatini Wallace J ◽  
S. Naveen Kumar ◽  
V. Negasta Smila ◽  
T. Nivitha ◽  
Stalin Nithaniyal ◽  
...  
Keyword(s):  
Moringa Oleifera ◽  
Therapeutic Potential ◽  
Biological Activities ◽  
Future Research ◽  
Phytochemical Analysis ◽  
Traditional Use ◽  
Phytochemical Study ◽  
Medicinal Uses ◽  
Pharmacological Significance ◽  
History Of

Moringa is a medicinally important genus that has long history of traditional use as a remedy to cure wounds and various ailments such as colds, diabetes, digestive problems etc. In addition, the species is consumed as a source of nutritive food and used as vegetables worldwide. The genus consists of 13 species that have been cultivated throughout Asia and Africa for their multiple purpose use value. The current study is aimed to validate the traditional medicinal uses of Moringa oleifera, provide scientific insights on the phytochemistry, biological activities and thereby correlating its therapeutic potential for future prospects. Analysis of phytochemical profile showed the presence of the major important bioactive compounds (saponin, tannin, flavonoids, phenolics, and reducing sugar) that were assessed in aqueous, methanolic aqueous and acetone-aqueous extracts following standard procedures. This study provides the foundation to explore the tribal medicinal use complemented with the scientific evaluation. Our study reinforce further phytochemical study with advanced technologies for future research opportunities of this species as it is an interesting plant containing commercially important active compounds that enable to determine pharmacological significance, and socio-economic potential.

Evaluation of Medicinal uses, Phytochemistry and Biological Activities of Adenia gummifera (Harv.) Harms -

2020 ◽  
Vol 10 (5) ◽  
pp. 280-286
Author(s):  
Alfred Maroyi
Keyword(s):  
Traditional Medicine ◽  
Democratic Republic Of Congo ◽  
Respiratory Infections ◽  
Biological Activities ◽  
Future Research ◽  
Scientific Publications ◽  
Medicinal Uses ◽  
Additional Information ◽  
Cytotoxicity Activities

Adenia gummifera (Harv.) Harms is a climber or liane widely used as traditional medicine throughout its distributional range in tropical Africa. Adenia gummifera occurs naturally in the Democratic Republic of Congo (DRC), Eswatini, Ethiopia, Kenya, Malawi, Mozambique, Seychelles, Somalia, South Africa, Tanzania, Uganda, Zambia and Zimbabwe. This study is aimed at providing a critical review of the medicinal uses, phytochemistry and biological activities of A. gummifera. Documented information on the medicinal uses, phytochemistry and biological activities of A. gummifera was collected from several online sources, which included Scopus, Google Scholar, PubMed and Science Direct. Additional information was gathered from pre-electronic sources such as book chapters, books, journal articles and scientific publications sourced from the university library. This study showed that the species is widely used as an emetic and a protective charm, and, as traditional medicine for infertility, sexually transmitted infections, gastro-intestinal infections, leprosy, respiratory infections, malaria and menstrual problems. Phytochemical compounds identified from the species include polyacetylenic diepoxide, alkaloids, flavonoids, flavonol, modeccin, proanthocyanidins, tetraphyllin, phenolics, polyphenol and tannins. Pharmacological research revealed that A. gummifera extracts and compounds isolated from the species have antibacterial, antifungal, acetylcholinesterase inhibitory (AChEI), anaesthetic, antioxidant, antiplasmodial and cytotoxicity activities. Future research on A. gummifera should focus on detailed phytochemical evaluations including toxicological, in vivo and clinical studies to corroborate the traditional medical applications of the species.

scholarly journals HELICHRYSUM CYMOSUM (L.) D.DON (ASTERACEAE): MEDICINAL USES, CHEMISTRY, AND BIOLOGICAL ACTIVITIES

2019 ◽  
pp. 19-26
Author(s):  
ALFRED MAROYI
Keyword(s):  
Biological Activities ◽  
Future Research ◽  
Pharmacological Properties ◽  
Journal Articles ◽  
Tropical Africa ◽  
Medicinal Uses ◽  
Additional Information ◽  
Cytotoxicity Activities ◽  
The University ◽  
Anti Hiv

Helichrysum cymosum is a valuable and well-known medicinal plant in tropical Africa. The current study critically reviewed the medicinal uses, phytochemistry and biological activities of H. cymosum. Information on medicinal uses, phytochemistry and biological activities of H. cymosum, was collected from multiple internet sources which included Scopus, Google Scholar, Elsevier, Science Direct, Web of Science, PubMed, SciFinder, and BMC. Additional information was gathered from pre-electronic sources such as journal articles, scientific reports, theses, books, and book chapters obtained from the University library. This study showed that H. cymosum is traditionally used as a purgative, ritual incense, and magical purposes and as herbal medicine for colds, cough, fever, headache, and wounds. Ethnopharmacological research revealed that H. cymosum extracts and compounds isolated from the species have antibacterial, antioxidant, antifungal, antiviral, anti-HIV, anti-inflammatory, antimalarial, and cytotoxicity activities. This research showed that H. cymosum is an integral part of indigenous pharmacopeia in tropical Africa, but there is lack of correlation between medicinal uses and existing pharmacological properties of the species. Therefore, future research should focus on evaluating the chemical and pharmacological properties of H. cymosum extracts and compounds isolated from the species.

scholarly journals From Traditional Usage to Pharmacological Evidence: Systematic Review ofGunnera perpensaL.

2016 ◽  
Vol 2016 ◽  
pp. 1-14 ◽  
Author(s):  
Alfred Maroyi
Keyword(s):  
Biological Activities ◽  
Pharmaceutical Products ◽  
Future Research ◽  
Pharmacological Activities ◽  
Sexually Transmitted ◽  
Animal Diseases ◽  
Wide Range ◽  
Medicinal Properties ◽  
Human And Animal Diseases

Gunnera perpensais the only species of the genusGunnerathat has been recorded in Africa. Its leaves, rhizomes, roots, and stems are reported to possess diverse medicinal properties and used to treat or manage various human and animal diseases and ailments.Gunnera perpensais an ingredient in many herbal concoctions and prescriptions which have been used to induce or augment labour, postnatal medication, to treat parasitic diseases, urinary complaints, kidney problems, general body pains, sexually transmitted infections, and many other diseases. Several classes of phytochemicals including alkaloids, benzoquinones, ellagic acids, flavonoids, phenols, proanthocyanidins, tannins, and minerals have been isolated fromG. perpensa. Scientific studies onG. perpensaindicate that it has a wide range of pharmacological activities including acetylcholinesterase, anthelmintic, antibacterial, antifungal, antinociceptive, anti-inflammatory, antioxidant, antitumour, lactogenic, and uterotonic.Gunnera perpensahas a lot of potential as a possible source of pharmaceutical products for the treatment of a wide range of both human and animal diseases and ailments. Some of the chemical compounds isolated fromG. perpensahave demonstrated various biological activities when investigated inin vitroassays. Future research should focus on the mechanisms of action of the isolated compounds, their efficacy, toxicity, and clinical relevance.

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