Fighting And Chasing The Rogue Virus-Covid19

2020 ◽  
Vol 11 (SPL1) ◽  
pp. 77-80 ◽  
Author(s):  
Pooja Shah ◽  
Waqar Naqvi
Keyword(s):  
Severe Acute Respiratory Syndrome ◽  
South Korea ◽  
The Novel ◽  
Indian Government ◽  
Social Patterns ◽  
Collective Goal ◽  
Community Transmission ◽  
Novel Coronavirus

The novel coronavirus of 2019, COVID-19, also known as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has spread from its origin Wuhan, China to the rest of the world.It is important to note that while the number of new cases has reduced in China lately, they have increased exponentially in other countries including South Korea, Italy and Iran. In India, the COVID-19 trajectory appears assured to change modes. While the number of incidents grew slowly in February, they doubled in just five days in mid-March from 100 to more than 236, and now at the end of April, the cases reported are 29,435.These numbers are possibly an underestimate of the infected and dead due to limitations of surveillance and testing. . The Indian government declared a countrywide shutdown for a period of 3 weeks from 24th of March to help prevent the spread of the virus. Most of the affected people had connection with flyers from covid-19 affected countries; some of them had no such interaction, indicating that community transmission could have started in several parts of India. Thus an important collective goal is to reduce the outbreak and to flatten the peak of the outbreak curve. Cooperation is a crucial tool in the COVID-19 battle. There is a need to identify and find a way around the particular threats, the overarching cultural and social patterns in our area. This article discusses the tactics thatshould build for handling the crisis.

scholarly journals Prioritizing Financial Crises Due to COVID-19

2021 ◽  
Vol 10 (1) ◽  
pp. 65-75
Author(s):  
Meghana Mishra ◽  
Pravudatta Mishra
Keyword(s):  
Financial Crises ◽  
The Novel ◽  
Indian Government ◽  
Work From Home ◽  
Product Service ◽  
Community Transmission ◽  
Precautionary Measures ◽  
Major Attention ◽  
Novel Coronavirus ◽  
Financial Transactions

In order to reduce the community-transmission of the novel coronavirus, precautionary measures require major attention. Reducing coronavirus transmission in the Indian population has included utilization of protective masks, which ranked in the first level, followed by hand hygiene, self-observations, respiratory manners, social distancing, and environmental cleanliness and ventilation, respectively. But the Indian Government has taken a good initiative by ordering a lockdown to provide safety to its population and sustainability to the environment or nature. People in some sectors are doing work from home to still the rate of transmission, but the financial transactions also stop. In some sectors (product/service), it is also not possible to work from home, and in India, the infrastructure or facilities or science is not that developed. Hence, the Indian economy is suffering. In this paper, an effort is taken to find the financial crises in India due to Pandemic COVID-19 and prioritize it by Topsis method.

scholarly journals Severe neutropenia in infants with severe acute respiratory syndrome caused by the novel coronavirus 2019 infection

2020 ◽  
Vol 222 ◽  
pp. 259-261 ◽  
Author(s):  
Elisabetta Venturini ◽  
Giordano Palmas ◽  
Carlotta Montagnani ◽  
Elena Chiappini ◽  
Francesco Citera ◽  
...  
Keyword(s):  
Severe Acute Respiratory Syndrome ◽  
Severe Neutropenia ◽  
The Novel ◽  
Novel Coronavirus

scholarly journals Does the novel coronavirus 2019 like heart more than the other family members of coronaviruses?

2020 ◽  
Vol 12 (2) ◽  
pp. 156-157
Author(s):  
Mohammad Mostafa Ansari Ramandi ◽  
Mohammadreza Baay ◽  
Nasim Naderi
Keyword(s):  
Middle East ◽  
Severe Acute Respiratory Syndrome ◽  
Family Members ◽  
Middle East Respiratory Syndrome ◽  
The Other ◽  
The Novel ◽  
The World ◽  
Future Challenges ◽  
Novel Coronavirus ◽  
Coronavirus Infections

The disaster due to the novel coronavirus disease 2019 (COVID-19) around the world has made investigators enthusiastic about working on different aspects of COVID-19. However, although the pandemic of COVID-19 has not yet ended, it seems that COVID-19 compared to the other coronavirus infections (the Middle East Respiratory Syndrome [MERS] and Severe Acute Respiratory Syndrome [SARS]) is more likely to target the heart. Comparing the previous presentations of the coronavirus family and the recent cardiovascular manifestations of COVID-19 can also help in predicting possible future challenges and taking measures to tackle these issues.

scholarly journals Respiratory Care in Corona

2021 ◽  
Vol 58 (2) ◽  
pp. 613-620
Author(s):  
Mustafa Amdani, Dr. Swaroopa Chakole
Keyword(s):  
Severe Acute Respiratory Syndrome ◽  
Human Life ◽  
The Body ◽  
Respiratory Care ◽  
The Novel ◽  
Specific Therapy ◽  
History Of ◽  
Novel Coronavirus ◽  
Almost All ◽  
The Impact

BACKGROUND The expanse of the coronavirus disease 2019 or COVID-19 is huge. The impact is multispectral and affected almost all aspects of human life. SUMMARY Respiratory impact of the COVID-19 is the most felt and widely reported impact. As the novel coronavirus maintained its history of affecting lungs as seen previously in severe acute respiratory syndrome (SARS) outbreak. Ventilators and oxygen support system are required mostly in comorbid patients particularly amongpatientsbearing illnesses like asthma, bronchial impairment and so on. CONCLUSION More study needs to be done in order to assess the impact on the respiratory functioning of the body. Respiratory care must be including proper instruments so that more efficient result can be obtained. Research is needed to promote the invention of specific therapy for targeted action for respiratory functioning improvement.

Tri-primer-enhanced strand exchange amplification combined with rapid lateral flow fluorescent immunoassay to detect SARS-CoV-2

The Analyst ◽  
2021 ◽  
Author(s):  
Linlin Zhuang ◽  
Jiansen Gong ◽  
Ming Ma ◽  
Yongxin Ji ◽  
Peilong Tian ◽  
...  
Keyword(s):  
Severe Acute Respiratory Syndrome ◽  
Lateral Flow ◽  
Strand Exchange ◽  
The Novel ◽  
The World ◽  
Novel Coronavirus

The novel coronavirus disease 2019 caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been surging rapidly around the world, which exposes humanity to unprecedented economic, social and...

scholarly journals Acute Kidney Injury in SARS-CoV-2 Infection: Direct Effect of Virus on Kidney Proximal Tubule Cells

2020 ◽  
Vol 21 (9) ◽  
pp. 3275 ◽  
Author(s):  
Manoocher Soleimani
Keyword(s):  
Acute Kidney Injury ◽  
Severe Acute Respiratory Syndrome ◽  
Proximal Tubule ◽  
Rna Viruses ◽  
Kidney Injury ◽  
The Novel ◽  
Proximal Tubule Cells ◽  
Severe Respiratory Infection ◽  
Tubule Cells ◽  
Novel Coronavirus

Coronaviruses (CoVs), including Severe Acute Respiratory Syndrome (SARS), Middle East Respiratory Syndrome (MERS), and the novel coronavirus disease-2 (SARS-CoV-2) are a group of enveloped RNA viruses that cause a severe respiratory infection which is associated with a high mortality [...]

scholarly journals Molecular epidemiology of the novel coronavirus that causes severe acute respiratory syndrome

The Lancet ◽  
2004 ◽  
Vol 363 (9403) ◽  
pp. 99-104 ◽  
Author(s):  
Y Guan ◽  
JSM Peiris ◽  
B Zheng ◽  
LLM Poon ◽  
KH Chan ◽  
...  
Keyword(s):  
Severe Acute Respiratory Syndrome ◽  
Molecular Epidemiology ◽  
The Novel ◽  
Novel Coronavirus

scholarly journals Computational Inference of Selection Underlying the Evolution of the Novel Coronavirus, Severe Acute Respiratory Syndrome Coronavirus 2

2020 ◽  
Vol 94 (12) ◽  
Author(s):  
Rachele Cagliani ◽  
Diego Forni ◽  
Mario Clerici ◽  
Manuela Sironi
Keyword(s):  
Severe Acute Respiratory Syndrome ◽  
Positive Selection ◽  
Common Ancestor ◽  
Purifying Selection ◽  
Population Variation ◽  
Binding Motif ◽  
The Novel ◽  
Species Barrier ◽  
The Common ◽  
Novel Coronavirus

ABSTRACT The novel coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that recently emerged in China is thought to have a bat origin, as its closest known relative (BatCoV RaTG13) was described previously in horseshoe bats. We analyzed the selective events that accompanied the divergence of SARS-CoV-2 from BatCoV RaTG13. To this end, we applied a population genetics-phylogenetics approach, which leverages within-population variation and divergence from an outgroup. Results indicated that most sites in the viral open reading frames (ORFs) evolved under conditions of strong to moderate purifying selection. The most highly constrained sequences corresponded to some nonstructural proteins (nsps) and to the M protein. Conversely, nsp1 and accessory ORFs, particularly ORF8, had a nonnegligible proportion of codons evolving under conditions of very weak purifying selection or close to selective neutrality. Overall, limited evidence of positive selection was detected. The 6 bona fide positively selected sites were located in the N protein, in ORF8, and in nsp1. A signal of positive selection was also detected in the receptor-binding motif (RBM) of the spike protein but most likely resulted from a recombination event that involved the BatCoV RaTG13 sequence. In line with previous data, we suggest that the common ancestor of SARS-CoV-2 and BatCoV RaTG13 encoded/encodes an RBM similar to that observed in SARS-CoV-2 itself and in some pangolin viruses. It is presently unknown whether the common ancestor still exists and, if so, which animals it infects. Our data, however, indicate that divergence of SARS-CoV-2 from BatCoV RaTG13 was accompanied by limited episodes of positive selection, suggesting that the common ancestor of the two viruses was poised for human infection. IMPORTANCE Coronaviruses are dangerous zoonotic pathogens; in the last 2 decades, three coronaviruses have crossed the species barrier and caused human epidemics. One of these is the recently emerged SARS-CoV-2. We investigated how, since its divergence from a closely related bat virus, natural selection shaped the genome of SARS-CoV-2. We found that distinct coding regions in the SARS-CoV-2 genome evolved under conditions of different degrees of constraint and are consequently more or less prone to tolerate amino acid substitutions. In practical terms, the level of constraint provides indications about which proteins/protein regions are better suited as possible targets for the development of antivirals or vaccines. We also detected limited signals of positive selection in three viral ORFs. However, we warn that, in the absence of knowledge about the chain of events that determined the human spillover, these signals should not be necessarily interpreted as evidence of an adaptation to our species.

scholarly journals COVID-19 in South Korea

2020 ◽  
Vol 96 (1137) ◽  
pp. 399-402 ◽  
Author(s):  
Jun Yong Choi
Keyword(s):  
Cardiovascular Disease ◽  
Severe Acute Respiratory Syndrome ◽  
South Korea ◽  
Reproduction Number ◽  
Current Situation ◽  
School Closure ◽  
Contact Tracing ◽  
Major Contributor ◽  
Novel Coronavirus ◽  
Underlying Diseases

A novel coronavirus (severe acute respiratory syndrome-CoV-2) that initially originated from Wuhan, China, in December 2019 has already caused a pandemic. While this novel coronavirus disease (COVID-19) frequently induces mild diseases, it has also generated severe diseases among certain populations, including older-aged individuals with underlying diseases, such as cardiovascular disease and diabetes. As of 31 March 2020, a total of 9786 confirmed cases with COVID-19 have been reported in South Korea. South Korea has the highest diagnostic rate for COVID-19, which has been the major contributor in overcoming this outbreak. We are trying to reduce the reproduction number of COVID-19 to less than one and eventually succeed in controlling this outbreak using methods such as contact tracing, quarantine, testing, isolation, social distancing and school closure. This report aimed to describe the current situation of COVID-19 in South Korea and our response to this outbreak.

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