scholarly journals Association between smoking and obstructive sleep apnea in adult and aged male population – A survey based study

2020 ◽  
Vol 11 (SPL3) ◽  
pp. 31-38
Author(s):  
Ranjith Raj VPRB ◽  
Karthik Ganesh Mohanraj ◽  
Murugan Thamaraiselvan
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Healthy Lifestyle ◽  
Survey Study ◽  
Male Population ◽  
Present Survey ◽  
Obstructive Sleep ◽  
Ethical Approval ◽  
Study Population ◽  
Spss Software

Smoking is defined as the process where a person inhales smoke either from burnt paper or electronic cigarette with or without containing tobacco.There are various drugs and substances which can be abused in the form of smoking. In the earlier days smoking cigarettes were branded as an healthy lifestyle. One such deteriorating effect of smoking could be OSA abbreviating to obstructive sleep apnea.Obstructive sleep apnea can be defined as the obstruction of the airway either completely or partially during the sleep. India being a country with a huge population of smokers has inadequate public health awareness. The aim of the study is to analyse if there is any association between smoking and obstructive sleep apnea. Our study is a survey based study among the Indian population.No ethical approval was required from the study due to the self volunteering of the participants.Sample size of this study was n=100. Pre tested questionnaire containing questions based on smoking,sleep patterns derived from Berlin’s & STOP BANG questionnaire. Questionnaire was circulated online among 100 participants above the age of 18 using Google Forms. The results were first imported to Excel then to SPSS software for further analysis. The present study population had male participation of 57%, and female participation of 43%, 59% of the study population were not aware of obstructive sleep apnea,75% of the participants declared that they are not addicted to smoking yet 25% are addicted,96% of the participants population found the study to be useful. The present survey study concluded that there may be an association between smoking and obstructive sleep apnea in the adult and aged population.

scholarly journals Adherence to the Mediterranean lifestyle is inversely associated with insomnia presence and severity: cross-sectional analysis in obstructive sleep apnea patients

2020 ◽  
Vol 79 (OCE2) ◽  
Author(s):  
Ioanna Kechribari ◽  
Meropi Kontogianni ◽  
Michael Georgoulis ◽  
Kallirroi Lamprou ◽  
Antonia Kalogera ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Healthy Lifestyle ◽  
Well Being ◽  
Sleep Habits ◽  
Upper Airways ◽  
Lifestyle Habits ◽  
Obstructive Sleep ◽  
The Mediterranean ◽  
Insomnia Symptoms

AbstractInsomnia is the most prevalent sleep disorder and frequently co-occurs with obstructive sleep apnea (OSA), a chronic disease characterized by repetitive pauses of breathing during sleep due to obstructions of the upper airways. The link between lifestyle and sleep quantity and quality is an area of intensive research, however data exploring associations between lifestyle habits and insomnia symptoms are still scarce. The aim of the present study was to investigate the potential association between the level of adherence to the Mediterranean lifestyle (ML), a healthy lifestyle pattern incorporating the prudent Mediterranean diet, adequate physical activity and healthy sleep habits, and insomnia presence and severity. The study sample consisted of 243 adult patients with polysomnography-diagnosed OSA. Participants’ insomnia-related disorders were evaluated through the Athens Insomnia Scale (AIS), an 8-item index ranging from 0 (absence of any sleep-related problem) to 24 (severe degree of insomnia); AIS values of > 6 were used to establish the diagnosis of insomnia. All patients were evaluated with regard to anthropometric indices and lifestyle habits, and adherence to the ML was estimated through the MEDLIFE index, a 28-item index ranging from 0 to 28, with higher values indicating greater proximity to the healthy lifestyle of the Mediterranean region. An inverse correlation was observed between the MEDLIFE index and total AIS (rho = -0.22, p = 0.001), as well as most individual components of AIS, including difficulty in sleep induction (rho = -0.14, p = 0.03), awakenings during the night (rho = -0.2, p = 0.008), short sleep duration (rho = -0.16, p = 0.01), low quality of sleep (rho = -0.13, p = 0.05), low well-being during the day (rho = -0.16, p = 0.02), and low functioning capacity during the day (rho = -0.15, p = 0.02). Patients with insomnia (AIS > 6), compared to those without (AIS ≤ 6), exhibited lower MEDLIFE index values [13 (11–15) vs. 14 (12–15), P = 0.002], had more severe OSA as assessed by the apnea-hypopnea index (AHI) [55 (24–87) vs. 35 (17–57) events/hour, P < 0.001] and tended to have higher body mass index (BMI) [35.0 (30.6–39.7) vs. 32.4 (29.5–38.6) kg/m2, P = 0.06]. According to logistic regression analysis, MEDLIFE index was inversely associated with the presence of insomnia (OR: 0.89, 95%CI: 0.80–0.99, P = 0.04) after adjustment for age, sex, smoking, BMI, daily energy intake and AHI. In conclusion, a higher adherence to the ML is inversely associated with insomnia presence and severity in patients with obstructive sleep apnea. Future research should assess whether this association applies in other samples, as well as whether the ML could be an efficient therapeutic tool alleviating or treating insomnia symptoms.

Outcome of adenotonsillectomy for obstructive sleep apnea in children under 3 years

2005 ◽  
Vol 132 (5) ◽  
pp. 681-684 ◽  
Author(s):  
Ron B. Mitchell ◽  
James Kelly
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
P Value ◽  
University Of New Mexico ◽  
Obstructive Sleep ◽  
Study Population ◽  
The Mean ◽  
The University ◽  
Head Neck ◽  
Respiratory Distress Index

OBJECTIVE: To study the outcome of adenotonsillectomy for obstructive sleep apnea (OSA) in children less than 3 years of age. DESIGN AND SETTING: Prospective study at the University of New Mexico Children's Hospital. Children with OSA underwent pre- and postoperative full-night polysomnography (PSG). Scores were compared using a paired t test. A P-value <0.05 was considered significant. RESULTS: The study population included 20 children. Fifteen (75%) were male. The mean age was 2.2 years (range, 1.1 to 3.0). Sixteen (80%) children had medical comorbidities. Over 25% of children had postoperative complications including laryngospasm and marked desaturations. The mean preoperative respiratory distress index (RDI) was 34.1 and the mean postoperative RDI was 12.2 ( P < 0.0001). After surgery, 7 (35%) children had an RDI < 5. Thirteen (65%) had a postoperative RDI ≥ 5 indicating persistent OSA. CONCLUSION AND SIGNIFICANCE: Children under 3 years show significant improvement in RDI after adenotonsillectomy for OSA, but they may develop complications after surgery. Postoperative PSG is recommended for children under 3 years of age to monitor the severity of persistent OSA. EBM rating: B-2. (Otolaryngol Head Neck Surg 2005;132:681-684.)

Abstract 120: Prevalence and Impact of Patent Foramen Ovale in Patients with Obstructive Sleep Apnea

2016 ◽  
Vol 36 (suppl_1) ◽  
Author(s):  
Phillip Camp ◽  
Abinash Achrekar ◽  
Umar Malik ◽  
Warren Laskey
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Patent Foramen Ovale ◽  
Right Atrial ◽  
Apnea Hypopnea Index ◽  
Foramen Ovale ◽  
Contrast Injection ◽  
Obstructive Sleep ◽  
Increased Risk ◽  
Study Population

Introduction: It is well known that obstructive sleep apnea (OSA) prevalence increases as body mass index (BMI) increases. Lesser known is patent foramen ovale (PFO) is found in 12 to 35 percent of adults. Patients with OSA experience nocturnal apnea which result in hypoxemia, elevation of right atrial pressure, and an increase in right to left shunting and a theoretical increased risk of stroke. A few studies have suggested an association between the severity of OSA and a PFO. As such, OSA diagnosis and therapy may be tailored to address right-to-left shunting in these patients. If the prevalence of PFO in OSA patients is increased, it may be appropriate to include transthoracic echocardiography (TTE) testing as a component of routine evaluation of patients with OSA. Hypothesis: We hypothesize that patients with hypoxemia related to OSA are more likely to have a PFO with right-to-left shunting than those with less dramatic hypoxemia. We hope to determine the prevalence and clinical relevance of intra-cardiac shunting in patients with OSA by prospectively analyzing and correlating polysomnography and TTE findings. Methods: 80 patients with OSA were referred for TTE by the UNM Sleep Center. All patients underwent saline contrast TTE in the UNM echo lab. The prevalence of PFO in the general UNM echo population was calculated over the last year for comparison. Results: Of 80 patients with varying degrees of OSA, 12.5% had right to left shunting. PFO was not statistically associated with DI (Desaturation Index), nor any AHI (Apnea Hypopnea Index). The only statistically significant association was between OSA and BMI (p=0.013). BMI associated with DI and AHI was statistically significant (p=0.003 and p=0.005, respectively). Over the last year, 216 PFO’s were found from 1858 echo studies with contrast injection performed at UNM with a prevalence rate of 11.6%. Conclusions: In contrast to previous studies, there was no association between OSA of any severity and PFO in our study population. There was a statistically significant association between BMI and OSA, which is well established. Our study prevalence was found to be similar to the UNM general echo population as well, indicating that OSA patients within our study group were not as likely to have an associated PFO.

The Prevalence of OSA Among an Adult Population With Down Syndrome Referred to a Medical Clinic

2019 ◽  
Vol 124 (1) ◽  
pp. 4-10 ◽  
Author(s):  
Michelle Cornacchia ◽  
Janis Sethness ◽  
Philip Alapat ◽  
Yu-Hsiang Lin ◽  
Cynthia Peacock
Keyword(s):  
Body Mass Index ◽  
Obstructive Sleep Apnea ◽  
Down Syndrome ◽  
Sleep Apnea ◽  
Adult Population ◽  
Retrospective Data ◽  
Medical Clinic ◽  
Obstructive Sleep ◽  
High Prevalence ◽  
Study Population

Abstract Obstructive sleep apnea (OSA) is a common sleep disorder affecting approximately 16% of adults (24% of men and 9% of women), and, if untreated, it can cause significant complications (Young, 2009). This study evaluates 56 adult patients with Down syndrome and analyzed retrospective data to determine the: (1) prevalence of OSA, (2) severity of OSA, and (3) association between body mass index (BMI) and OSA. Of those participants that had polysomnography (PSG) testing available, 82.1% were diagnosed with OSA, divided by severity into mild (45.7%), moderate (15.2%), and severe (39.1%) levels. Because of the high prevalence of OSA among our study population, we recommend that all adults with DS be screened for OSA with PSG.

Relevance of obstructive sleep apnea and smoking: Obstructive sleep apnea and smoking

2020 ◽  
Author(s):  
Ayse Didem Esen ◽  
Meltem Akpinar
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Rem Sleep ◽  
Demographic Data ◽  
Apnea Hypopnea Index ◽  
Obstructive Sleep ◽  
Study Results ◽  
Significant Difference ◽  
Study Population ◽  
The Impact

Abstract Background The data concerning the association of smoking and obstructive sleep apnea (OSA) are limited. The effects of cigarette smoking on OSA still remain obscure. Objectives To reveal the impact of smoking on obstructive sleep apnea. Methods About 384 patients with the diagnosis of OSA through full night polysomnographic (PSG) examination were included to the study. The demographic data (age, sex and BMI), complaints and medical history, status of smoking as non-smokers and smokers, smoking frequency (cigarettes/day), polysomnograhic data comprising apnea hypopnea index (AHI), non-REM sleep AHI (NREM AHI), REM sleep AHI (REM AHI), minimum oxygen saturation (min SaO2) were recorded for all the subjects. Non-smokers and smokers were compared in terms of severity of OSA. Results The study population consisted of 384 subjects, 253 males and 131 females. Smoking frequency was not found correlated with OSA severity. Among smokers, males had higher severe OSA rate (P = 0.002, P &lt; 0.05). In subjects with BMI &lt; 30, severe OSA rate was higher in smokers (34.44% versus 21%) (P = 0.027, P &lt; 0.05). Conclusions Our study detected higher rate of severe OSA in male smokers and smokers with BMI &lt; 30. PSG data did not yield statistically significant difference in non-smokers and smokers. OSA severity was not found correlated with smoking frequency. Along with the study results, the impact of smoking on OSA is still controversial. Prospective studies with larger sample size may be contributive to further evaluation of the association of OSA with smoking.

Prevalence and Risk Factors for Obstructive Sleep Apnea Syndrome Among Children and Adolescents with Cleft lip and Palate: A Survey Study in Hong Kong

2021 ◽  
pp. 105566562110683
Author(s):  
A. C. H. Ho ◽  
F. Savoldi ◽  
R. W. K. Wong ◽  
S. C. Fung ◽  
S. K. Y. Li ◽  
...  
Keyword(s):  
Risk Factors ◽  
Obstructive Sleep Apnea ◽  
Hong Kong ◽  
Sleep Apnea ◽  
Children And Adolescents ◽  
Cleft Lip ◽  
Sleep Apnea Syndrome ◽  
Survey Study ◽  
Obstructive Sleep ◽  
Secondary Palate

Objective To investigate the prevalence of obstructive sleep apnea syndrome (OSAS) risk and related risk factors among children and adolescents of Hong Kong with cleft lip and/or palate (CL/P). Design Retrospective survey study adopting three questionnaires, obstructive sleep apnea-18 (OSA-18), pediatric sleep questionnaire-22 (PSQ-22), and modified Epworth Sleepiness Scale (ESS). Settings Multicenter study in two public hospitals. Patients A total of 351 Chinese children and adolescents with non-syndromic CL/P (6-18-year-old, 57% males) visited between September 2017 and November 2019, with primary palatal repair surgery done before 3-year-old. Main Outcome Measure Positive OSAS risk was determined based on cut-off ≥60 for OSA-18, ≥8 for PSQ-22, and >8 for ESS. Age, sex, overweight presence, cleft type, embryonic secondary palate involvement, palatal repair surgery, palatal revision surgery, and orthodontic treatment were analyzed as possible risk factors. Results A total of 9.5% of patients had positive OSAS risk based on OSA-18, 13.6% based on PSQ-22, and 13.2% according to ESS. A higher prevalence of patients with positive OSAS risk was of younger age (OSA-18, p = .034), had cleft involving embryonic secondary palate (PSQ-22, p = .009), and history of fixed orthodontic treatment (ESS, p = .002). The regression model identified only involvement of embryonic secondary palate as a risk factor (PSQ-22, odds ratio = 3.7, p = .015). Conclusions OSAS risk among children and adolescents of Hong Kong with CL/P was 9.5% to 13.6%. Patients at higher risk were those with cleft involving embryonic secondary palate. OSAS risk assessment may be influenced by different aspects of the disease spectrum, and a multimodal approach should be considered for such assessment.

Predicting Obstructive Sleep Apnea Status With the Reflux Symptom Index in a Sleep Study Population

2020 ◽  
Vol 130 (12) ◽  
Author(s):  
Meron Teklu ◽  
Christopher J. Gouveia ◽  
Amulya Yalamanchili ◽  
Saied Ghadersohi ◽  
Caroline P. E. Price ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Reflux Symptom ◽  
Reflux Symptom Index ◽  
Symptom Index ◽  
Sleep Study ◽  
Obstructive Sleep ◽  
Study Population

scholarly journals Intergenic SNPs in Obstructive Sleep Apnea Syndrome: Revealing Metabolic, Oxidative Stress and Immune-Related Pathways

Diagnostics ◽  
2021 ◽  
Vol 11 (10) ◽  
pp. 1753
Author(s):  
Dimitrios G. Raptis ◽  
George D. Vavougios ◽  
Dimitra I. Siachpazidou ◽  
Chaido Pastaka ◽  
Georgia Xiromerisiou ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Obstructive Sleep Apnea Syndrome ◽  
In Silico ◽  
Sleep Apnea Syndrome ◽  
Binary Logistic Regression Model ◽  
Multiple Cancer ◽  
Obstructive Sleep ◽  
Study Population ◽  
Apnea Syndrome

There is strong evidence supporting the contribution of genetic factors to obstructive sleep apnea syndrome (OSAHS) susceptibility. In the current study we analyzed both in a clinical cohort and in silico, four single nucleotide polymorphisms SNPs, rs999944, rs75108997, rs35329661 and rs116133558 that have been associated with OSAHS. In 102 patients with OSAHS and 50 healthy volunteers, genetic testing of the above polymorphisms was performed. Polymorphism rs116133558 was invariant in our study population, whereas polymorphism rs35329661 was more than 95% invariant. Polymorphism rs999944 displayed significant (>5%) variance in our study population and was used in the binary logistic regression model. In silico analyses of the mechanism by which these three SNPs may affect the pathophysiology of OSAHS revealed a transcriptomic network of 274 genes. This network was involved in multiple cancer-associated gene signatures, as well as the adipogenesis pathway. This study, uncover a regulatory network in OSAHS using transcriptional targets of intergenic SNPs, and map their contributions in the pathophysiology of the syndrome on the interplay between adipocytokine signaling and cancer-related transcriptional dysregulation.

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