scholarly journals A study on the prescription pattern of anti-hypertensive drugs in general hospital of Al-Quwayyah, Saudi Arabia

2018 ◽  
Vol 9 (1) ◽  
pp. 154
Author(s):  
Faisal Al-Otaibi
Keyword(s):  
Saudi Arabia ◽  
Combination Therapy ◽  
General Hospital ◽  
Beta Blocker ◽  
Drug Combination ◽  
Antihypertensive Drugs ◽  
Hypertensive Patients ◽  
Patient Interviews ◽  
Trade Name ◽  
Combination Drugs

An open, non-comparative, observational study conducted on hypertensive patients attending the OPD medicine of Al-Quwayyah general hospital, Al-Quwayyah, Saudi Arabia by conducting patient interviews and recording the data on drug utilization form based on JNC-7 and WHO format. Total of 212 hypertensive patients were included in study, prevalence of hypertension was found to be higher in male in age group of 45-59 years, smoker and pre-hypertension stage. 60.38% antihypertensive drugs prescribed by trade name and by 39.62 % by generic name. It was observed that Monotherapy were most prescribed mode of drugs and in Combination therapy the frequency and percentage of two drug combination were found 3/4 of the total combination therapy similarly three combination drugs were 16.72 % and more than three drugs combination were only 3.41 %. It was observed that Beta blocker were prescribed most (28.77%) among antihypertensive drugs followed by calcium channel blocker (25.47%), ACE inhibitor (17.92%), Diuretics (12.74%), AT II Receptor Blocker (9.4%) and alpha blocker were found to be least one. The Conclusion of study was found that the Utilization pattern of Antihypertensive drug in General hospital Al-Quwayyah, Saudi Arabia indicates that Beta blocker were prescribed individually most as monotherapy and if combination therapy then 2 drug combination of antihypertensive drugs. Keywords: Prescription; Antihypertensive drugs; Beta Blocker

scholarly journals DRUG UTILIZATION BASED ADRS MONITORING OF ANTIHYPERTENSIVE AGENTS PRESCRIBED IN AL-QUWAYIYAH GENERAL HOSPITAL, SAUDI ARABIA

2018 ◽  
Vol 10 (3) ◽  
pp. 22
Author(s):  
Md Salahuddin Ansari ◽  
Faisal Al-otaibi
Keyword(s):  
Saudi Arabia ◽  
Calcium Channel ◽  
General Hospital ◽  
Drug Utilization ◽  
Calcium Channel Blockers ◽  
Antihypertensive Drugs ◽  
Antihypertensive Agents ◽  
Channel Blockers ◽  
Hypertensive Patients ◽  
Patient Interviews

Objective: To monitor drug utilization based adverse drug reactions (ADRs) of antihypertensive agents prescribed in Al-Quwayiyah general hospital, Saudi Arabia.Methods: An open, non-comparative, observational study was conducted on hypertensive patients attending the medicine outpatient department of Al-Quwayyah general hospital, Al-Quwayyah, Saudi arabia. Data were collected by conducting patient interviews. Data were captured for adverse drug reaction monitoring based on Narinjo scale and WHO format.Results: 25 ADRs were observed out of 212 hypertensive patients. Incidence was found to be higher in patients more than 40 y age, and females experienced more ADRs (n = 16, 7.54%) than males, 9 (4.62%). Combination therapy was associated with more number of ADRs (64.0%) as against monotherapy (36.0%). Calcium channel blockers were found to be the most frequently associated drugs with ADRs (n = 8), followed by diuretics (n = 6), and β-blockers (n = 5). Among individual drugs, amlodipine was found to be the commonest drug associated with ADRs (n = 8), followed by torasemide (n = 4). ADRs associated with the central nervous system was found to be the most frequent (48.0%) followed by musculoskeletal complaints (20.0%) and respiratory system disorders (16.0%).Conclusion: ADRs were experienced by taking the antihypertensive drugs prescribed in Al-Quwayyah general hospital, Saudi arabia. The findings would be useful for physicians in rational prescribing. Calcium channel blockers were found to be the most frequently associated drugs with ADRs.

scholarly journals Study of prescribing pattern of antihypertensive drugs in diabetic patients in a tertiary care centre, Vizianagaram, India

2019 ◽  
Vol 8 (6) ◽  
pp. 1192
Author(s):  
Vanathi Elenchezhiyan ◽  
Sachidananda Moorthy ◽  
Sagar M. K. ◽  
Bheemesh Naidu Mattam ◽  
Suresh Babu Sayana
Keyword(s):  
Combination Therapy ◽  
Antihypertensive Drug ◽  
Antihypertensive Drugs ◽  
Tertiary Care ◽  
Prescribing Patterns ◽  
Diabetic Patients ◽  
Care Hospital ◽  
Tertiary Care Centre ◽  
Prescribing Pattern ◽  
Hypertensive Patients

Background: Diabetes mellitus (DM) and Hypertension (HTN) are the two major chronic disorders frequently coexisting, with increased incidence with age. HTN is about twice as common in patients with DM. Prescribing pattern are powerful tools to ascertain the role of drugs in society. There are many variations in prescribing patterns of antihypertensive drugs in patients with HTN and DM. Since these patients requires lifelong treatment it has enormously increased the burden of patients particularly in developing countries like India. Physician needs to be more concerned while choosing drugs for the patients with HTN and DM. In a tertiary care hospital, there is a real need for drug utilization study to determine the appropriate, more safe and effective patterns of drug therapy among diabetic hypertensive patients.Methods: A Cross sectional observational study was conducted in Maharajah’s Institute of Medical Sciences from December 2016 to May 2018. A total of 360 prescriptions of the patients with hypertension and coexisting diabetes were analyzed. The prescriptions prescribed to these patients were collected, assessed and the following parameters were noted. The treatment pattern of different group of drugs for HTN with co-existing DM was evaluated. The intended work was divided into three steps: Step 1: To collect the prescriptions of hypertensive patients with DM. Step 2: To separate the prescriptions prescribing anti hypertensive Drugs. Step 3: To statistically analyze the prescriptions. Relevant information was recorded in a structured proforma & data was evaluated.Results: In this study it was found that 36% of the patients were in the age group of 51-60 years with female preponderance among diabetic hypertensive patients. 77% of patients were treated with single antihypertensive drug and 23% of patients were treated with antihypertensive drug combinations. In monotherapy, telmisartan was most commonly prescribed. In combination therapy, amlodipine and telmisartan followed by amlodipine and atenolol were used.Conclusions: In this study monotherapy was preferred compared to combination therapy and adherence to the JNC 7 guidelines was good except in case of usage of diuretics.

scholarly journals PROFIL PASIEN HIPERTENSI DI POLIKLINIK GINJAL-HIPERTENSI

e-CliniC ◽  
2016 ◽  
Vol 4 (1) ◽  
Author(s):  
Marillyn M. Tamburian ◽  
Emma Sy. Moeis ◽  
Fandy Gosal
Keyword(s):  
Blood Pressure ◽  
Retrospective Study ◽  
General Hospital ◽  
Medical Records ◽  
Causes Of Death ◽  
Antihypertensive Drugs ◽  
Medical Condition ◽  
Hypertensive Patients ◽  
Hypertension Clinic ◽  
Diastolic Hypertension

Abstract : Hypertension is chrocnic medical condition which the blood pressure has elevated above 140mmHg systolic and 90 mmHg diastolic. Hypertension is one of top 10 of the causes of death worldwide. It is because hypertension affects in damaged of some organs like heart, brain, renal, retinal, ect.The purpose of this study is to give the information about profile of hypertensive patients and about antihypertensive drugs which most commonly used in Prof. Dr. R. D. Kandou General Hospital Manado.This is descriptive retrospective study. The data had been taken from medical records in Nephrology and Hypertension Clinic at Prof. Dr. R. D. Kandou General Hospital Manado.Keywords : Hypertension, Complication, Antihypertensive drugsAbstrak : Hipertensi merupakan kondisi dimana tekanan darah sistol diatas 140 mmHg dan tekanan darah diastol diatas 90 mmHg.Hipertensi menjadi salah satu penyebab kematian terbanyak didunia karena hipertensi dapat mempengaruhi kerusakan pada organ-organ target yang lain seperti organ jantung, otak, ginjal, mata dan lain-lain.Tujuan penelitian ini untuk memberikan gambaran tentang profil pasien hipertensi serta jenis obat antihipertensi yang digunakan di poliklinik ginjal-hipertensi RSUP Prof. Dr. R. D. Kandou Manado periode Oktober 2014 - Maret 2015.Penelitian ini merupakan jenis penelitian deskriptif retrospektif dengan data sekunder di poliklinik ginjal-hipertensi RSUP. Prof. Dr. R. D. Kandou Manado periode Oktober 2014 - Maret 2015. Sampel penelitian sebanyak 311 pasien.Kata Kunci : Hipertensi, Komplikasi, Obat Antihipertensi

Landscape of Combination Therapy – Which Way Forward? Proceedings of the Satellite Symposium Held at the ESH European Meeting on Hypertension and Cardiovascular Protection, 27 April 2012, London

2012 ◽  
Vol 8 (3) ◽  
pp. 192
Author(s):  
Patricia Fonseca ◽  
Anna F Dominiczak ◽  
Stephen Harrap ◽  
◽  
◽  
...  
Keyword(s):  
Blood Pressure ◽  
High Risk ◽  
Combination Therapy ◽  
Enzyme Inhibitor ◽  
Synergistic Effects ◽  
Term Treatment ◽  
Angiotensin Ii Receptor Blocker ◽  
Angiotensin Ii Receptor ◽  
Hypertensive Patients ◽  
Long Term Treatment

Early combination therapy is more effective for hypertension control in high-risk patients than monotherapy, and current guidelines recommend the use of either an angiotensin-converting enzyme inhibitor (ACEI) or angiotensin II receptor blocker (ARB) for first-line therapy in patients younger than 55 years. Recent evidence shows that ACEIs reduce mortality, whereas ARBs show no apparent benefit despite their blood pressure lowering action. However, it is important to consider which blood pressure parameters should be targeted given that different drugs have distinct effects on key parameters. Remarkably, a high percentage of hypertensive patients whose treatment has brought these parameters within target ranges still remain at high risk of cardiovascular disease due to additional risk factors. Combination therapy with synergistic effects on blood pressure and metabolic control should thus be considered for the long-term treatment of hypertensive patients with co-morbid conditions.

EVALUASI RASIONALITAS PENGGUNAAN DAN PEMBERIAN OBAT PADA PASIEN HIPERTENSI GERIATRI DI PUSKESMAS TAJINAN PERIODE JANUARI – DESEMBER 2019

2020 ◽  
Vol 5 (2) ◽  
pp. 268-277
Author(s):  
Luluk Anisyah ◽  
◽  
Wibowo Wibowo
Keyword(s):  
Correlation Analysis ◽  
Medical Record ◽  
Significant Relationship ◽  
Antihypertensive Drugs ◽  
Hypertension Management ◽  
Hypertensive Patients ◽  
Primary Health ◽  
Data Collection Sheet ◽  
Dose Accuracy ◽  
Accuracy Data

Increasing the number of elderly causes an increase in health problems one of which is associated with hypertension which can cause complications and death. The purpose of this study was to determine the description and accuracy of the use of antihypertensive drugs in geriatric patients who were diagnosed with hypertension at the Tajinan Primary Health in Malang in the period January-December 2019. This study was an observational or non-experimental study conducted using retrospective medical record data. The measuring instrument used was the data collection sheet from the medical record, the Consensus for Hypertension Management 2019 to see the accuracy of indications, patient accuracy, drug accuracy, and dose accuracy. Data analysis using Correlation Test. The results of the correlation analysis showed that the resulting Standardize estimates were 0.002 (p <0.05) which showed that there was a significant relationship between sexes with the occurrence of hypertension. The results of the correlation analysis showed that the resulting Standardize estimates were 0.001 (p <0.05) which means that there was a significant relationship between the accuracy of the types of antihypertensive drugs used in hypertensive patients. The conclusion is that the rationality evaluation of the use and administration of drugs in hypertensive patients at the Tajinan Primary Health in Malang based on the 2019 Hypertension Management Consensus guidelines shows the accuracy both in terms of indication, drug, patient and dose.

scholarly journals Antihypertensive Efficacy of Fixed Combination of Amlodipine and Ramipril in Patients with Arterial Hypertension and Very High Cardiovascular Risk

2019 ◽  
Vol 14 (6) ◽  
pp. 840-845
Author(s):  
O. Yu. Korennova ◽  
S. P. Podolnaya ◽  
E. P. Prihodko ◽  
E. A. Turusheva ◽  
S. N. Starinskaya ◽  
...  
Keyword(s):  
Cardiovascular Risk ◽  
Coronary Artery ◽  
Fixed Combination ◽  
Antihypertensive Drugs ◽  
Antihypertensive Efficacy ◽  
High Cardiovascular Risk ◽  
Hypertensive Patients ◽  
Coronary Artery Stenting ◽  
History Of ◽  
Very High

Aim. To evaluate the antihypertensive efficacy and tolerability of a fixed combination of amlodipine and ramipril in hypertensive patients with very high cardiovascular risk. Material and methods. A retrospective cohort study of real clinical practice of prescribing antihypertensive drugs according to 255 medical records of outpatient hypertensive patients with a history of acute coronary syndrome (ACS) and coronary artery stenting was performed in the first part. An open observational study was performed in the second part. 69 people older than 18 years with a history of ACS and coronary artery stenting, without reaching the target blood pressure (BP) level while using free combinations of antihypertensive drugs and with indications for a fixed combination of ramipril and amlodipine were included into the study. Analysis of self-monitoring of BP, office BP, daily BP monitoring (ABPM) and patients’ adherence to treatment (Morisky-Green test) initially, after 4 and after 12 weeks of taking the fixed combination of ramipril and amlodipine was performed to assess the clinical efficacy of the studied drug. Results. It was found that 42.0% of patients did not follow the recommendations for regular intake of antihypertensive drugs. So, hypertension of all patients regarded as false-refractory, which was the basis for the prescription of the fixed combination of ramipril and amlodipine in accordance with clinical guidelines for the diagnosis and treatment of hypertension. After 4 weeks of therapy, there was significant decrease in office BP with the achievement and preservation of the target level by the 12th week, normalization to the 12th week of day and night BP variability in 54.9% of patients. 78.0% of patients followed medical recommendations for regular administration of antihypertensive drugs, none of the patients had adverse events. Conclusion. The use of fixed combinations of drugs, in particular, amlodipine and ramipril as a part of multicomponent therapy in hypertensive patients with very high cardiovascular risk, led to the achievement of target BP by the 4th week of therapy and stable preservation of antihypertensive effect in 12 weeks of treatment as well as gradual normalization of day and night BP variability in more than half of patients. Fixed combination of ramipril and amlodipine allowed to improve adherence of patients to cardiovascular diseases.

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