APATITES FORMATION ON ELECTRODEPOSITED CALCIUM PHOSPHATES IN THE Ca(NO3)2 / NH4H2PO4 AND CаCOз / Ca(H2PO4)2 SYSTEMS

Методом электрохимического осаждения на титановых пластинах при комнатной температуре в двухэлектродной ячейке при постоянной плотности тока 30 мА/см и времени осаждения 10 мин получены кальцийфосфатные покрытия: брушитные в системе Ca (NO )/ NH H PO при pH = 4 и композитные (брушит/кальцит/апатит) в системе CaCOjCa (HPO ) при pH = 5. Выдерживанием кальцийфосфатных покрытий обоих типов в модельном растворе SBF в течение 1 месяца определяли апатитообразующую способность (биоактивность). Новообразованный аморфизированный апатитовый слой после термообработки при 800°С кристаллизовался в Д -трикальцийфосфат/гидроксиапатит на брушитных покрытиях и в гидроксиапатит на композитных покрытиях за счет присутствия кальцита, карбонат-ионы которого являются инициаторами образования гидроксиапатита, а также апатитных наночастиц в исходном покрытии. Полученные кальцийфосфатные покрытия перспективны в качестве биопокрытий повышающих остеоинтеграцию металлических имплантатов. Calcium phosphate coatings on titanium plates were obtained by electrochemical deposition at room temperature in a two-electrode cell at a constant current density of 30 mA/sm and a deposition time of 10 min, and brushite coatings from Ca (NO )/NHHPO system at pH = 4, and composite (brushite/calcite/apatite) coatings from the CaCO/ Ca(HPO) system at pH = 5. The apatite-forming ability (bioactivity) was determined by soaking both types of calcium phosphate coatings in a model SBF solution during month. The newly formed amorphized apatite layer after heat treatment at 800 °С crystallized into p -tricalcium phosphate/hydroxyapatite on brushite coatings and hydroxyapatite on composite coatings due to the presence of calcite, whose carbonate ions initiate formation of hydroxyapatite, as well as apatite nanoparticles in the initial coating. The obtained calcium phosphate coatings are promising as biocoatings capable to increase osseointegration of metal implants.

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Bioactivity, Wear and Corrosion Resistant Properties of Rare Earth/Calcium Phosphate Composite Coatings

Key Engineering Materials ◽

10.4028/www.scientific.net/kem.368-372.1194 ◽

2008 ◽

Vol 368-372 ◽

pp. 1194-1197 ◽

Cited By ~ 1

Author(s):

Chen Ma ◽

Ying Hui Wang ◽

Mu Qin Li ◽

Li Jie Qu

Keyword(s):

Rare Earth ◽

Calcium Phosphate ◽

Composite Coatings ◽

Xrd Analysis ◽

Wear Properties ◽

Corrosion Resistant ◽

Phosphate Coatings ◽

Wear And Corrosion ◽

Micro Arc Oxidation ◽

Calcium Phosphate Coatings

Rare earth/calcium phosphate composite coatings were fabricated on the surface of Ti-6Al-4V by micro-arc oxidation (MAO) technique. The wear properties and corrosion resistant of rare earth/ calcium phosphate composite coatings in the simulated body fluid (SBF) have been investigated and the bioactivity of the composite coatings were evaluated. The results show that the friction coefficient of the composite coatings in the SBF is only 0.15~0.18 and the anode polarization potential of the coating has been obviously enhanced about 0.18V compared with that of coatings of calcium phosphate coatings. So the composite coatings have excellent wear and corrosion resistant properties. XRD analysis indicates that the composite coatings can induce hydroxyapatite to form on its surface after soaked in SBF for 9d, which shows that the composite coatings own good bioactivity.

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Biocompatibility of Modified Osteoinductive Calcium-Phosphate Coatings of Metal Implants

Bulletin of Experimental Biology and Medicine ◽

10.1007/s10517-017-3617-1 ◽

2017 ◽

Vol 162 (3) ◽

pp. 366-369 ◽

Cited By ~ 7

Author(s):

T. S. Zaporozhets ◽

A. V. Puz’ ◽

S. L. Sinebryukhov ◽

S. V. Gnedenkov ◽

T. P. Smolina ◽

...

Keyword(s):

Calcium Phosphate ◽

Metal Implants ◽

Phosphate Coatings ◽

Calcium Phosphate Coatings

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Calcium Phosphate Coatings on Titanium Alloy via an Electrodeposition Method

Key Engineering Materials ◽

10.4028/www.scientific.net/kem.330-332.549 ◽

2007 ◽

Vol 330-332 ◽

pp. 549-552

Author(s):

Marco A. Lopez-Heredia ◽

Pierre Weiss ◽

Pierre Layrolle

Keyword(s):

Calcium Phosphate ◽

Deposition Time ◽

Calcium Phosphates ◽

Factors Affecting ◽

Electrodeposition Method ◽

Phosphate Coatings ◽

Calcium Phosphate Particles ◽

Current Densities ◽

Main Factors ◽

Calcium Phosphate Coatings

Calcium phosphates coatings were deposited onto titanium discs via en electrodeposition method. Discs were blasted with calcium phosphate particles and etched in a mixture of sulfuric and fluoric acids. Temperatures from 25 to 80°C and current densities from 8 to 120 mA/ cm2 were used. Deposition times tested were between 10 and 120 min. The electrolyte consisted of a super saturated solution stirred at 250 rpm. The amount of magnesium (Mg2+) and carbonate (HCO3-) ions was varied from 0 to 1 mM. Coatings increased in thickness by increasing deposition time. The different amounts of Mg2+ and HCO3- affected the homogeneity and morphology of the coatings. Main factors affecting the deposition were temperature of electrolyte and current density.

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Antibacterial Titanium/Calcium Phosphate Implant Surfaces

Key Engineering Materials ◽

10.4028/www.scientific.net/kem.396-398.299 ◽

2008 ◽

Vol 396-398 ◽

pp. 299-302 ◽

Cited By ~ 1

Author(s):

Cornelia Prinz ◽

Hans Georg Neumann

Keyword(s):

Calcium Phosphate ◽

Titanium Oxide ◽

Antibacterial Effect ◽

Composite Coatings ◽

Antibacterial Properties ◽

Antibacterial Effects ◽

Phosphate Coatings ◽

Calcium Phosphate Layer ◽

Copper Phosphate ◽

Calcium Phosphate Coatings

The antibacterial effects of titanium oxide/calcium phosphate and calcium phos-phate/copper phosphate composite coatings have been investigated. Implant-like rough blasted tita-nium substrates are covered by a native titanium oxide layer. Together with the electrodeposited calcium phosphate layer a clear antibacterial effect has been observed. Electrodeposited calcium phosphate coatings were also dipped in aqueous copper sulphate solutions to convert partly calcium phosphate to copper phosphate. The antibacterial properties of such coatings can be controlled and adjusted to the clinical setting and to specific indications. Patient-tailored antibacterial treatments seem to be possible and may be of special interest for high-risk operations.

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Characterization of Calcium Phosphate with an Anodic TiO2 Nanotube Layer on Titanium Screw for Biomedical Application

Advanced Materials Research ◽

10.4028/www.scientific.net/amr.852.251 ◽

2014 ◽

Vol 852 ◽

pp. 251-255

Author(s):

Ya Jing Yan ◽

Yong Huang ◽

Qiong Qiong Ding ◽

Xiao Feng Pang

Keyword(s):

Calcium Phosphate ◽

Biomedical Application ◽

Calcium Phosphates ◽

Alkaline Treatment ◽

Calcium Phosphate Coating ◽

X Ray Diffraction ◽

Titanium Screw ◽

Phosphate Coatings ◽

Titanium Screws ◽

Calcium Phosphate Coatings

The present paper reports a novel solution to develop a calcium phosphates (CaPs) coating with an anodic nanotubular TiO2layer on titanium screw by electrochemical disposition (ECD). The elemental composition of coatings was examined by energy dispersive spectroscopy (EDS), the surface mopholoy was characterized with scanning electron microscopy (SEM), and the functional groups and crystalline phase were analyzed using Fourier transform infrared spectroscopy (FTIR) and X-ray diffraction (XRD). Furthermore, the bioactivity was tested by immersion in simulated body fluid (SBF) for 7 days. The results showed that a nanotubular TiO2layer was established which has about 100 mm diameter and the calcium phosphate coatings have higher bioactivity and porosity compared with uncoated titanium screws, which make the coating more conductive to cell adhesion. Using alkaline treatment, the calcium phosphate coating could transform into hydroxyapatite (HAp), making the coating closer to the biological complement. This provides a valuable tool for biomedical applications.

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Biomimetic calcium phosphates-based coatings deposited on binary Ti-Mo alloys modified by laser beam irradiation for biomaterial/clinical applications

MRS Advances ◽

10.1557/adv.2018.118 ◽

2018 ◽

Vol 3 (30) ◽

pp. 1711-1718 ◽

Cited By ~ 1

Author(s):

Marcio Luiz dos Santos ◽

Carla dos Santos Riccardi ◽

Edson de Almeida Filho ◽

Antonio C. Guastaldi

Keyword(s):

Heat Treatment ◽

Calcium Phosphate ◽

Laser Beam ◽

Calcium Phosphates ◽

Clinical Applications ◽

Beam Irradiation ◽

Phosphate Coatings ◽

Laser Beam Irradiation ◽

Biomimetic Method ◽

Calcium Phosphate Coatings

ABSTRACTBiomimetic Method has been widely used to prepare calcium phosphate coatings on Ti and its alloys. This modification is based on a Synthetic/simulated Body Fluid (BSF) which facilitates the mimicking of the biological process in order to provide hard tissue repairs. The formation of HA and other calcium phosphates under biological medium and SBF occurs in the presence of Ca2+ and PO43- ions, as well as essential ions such as: Mg2+, HCO3-, K+ and Na+. Ti-15Mo alloy samples were irradiated by pulsed Yb: YAG pulsed laser beam under air and atmospheric pressure. Sequentially, calcium phosphate coatings were deposited on the irradiated surfaces by the biomimetic method. The biomimetic calcium phosphates-based surfaces were submitted to heat treatment conditions at 350°C and 600°C. The present study correlates two conditions of fluency (1,91 and 5,54 J.cm-2) as established have a sufficient energy to promote ablation on the laser beam irradiated surfaces. Likewise, it has been demonstrated the processes of fusion and fast solidification from the laser beam irradiation, under ambient atmosphere, inducing the formation of stoichiometric TiO2 and non-stoichiometric titanium oxides, including Ti3O5, TiO, Ti3O and Ti6O with different oxide percentages depending on the fluency applied. Besides that, laser modification has allowed a clean and reproducible process, providing no traces of contamination, an important feature for clinical applications. The physico-chemical and morphological analysis indicated the formation of a multiphase coatings depending on the heat treatment temperature performed to 350 °C (ACP1 and 2, HAD, HA phases) and 600 °C (HAD, HA and β-TCP phases). It is worth noting that multiphasic bioceramic systems has been gaining attention for biomedical applications. Thus, the laser beam irradiation associated to bioactive coatings of calcium phosphates of biological interest have shown to be promising and economically feasible for use in dental and orthopedic implants.

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Study of Titanium Surface Topography Influence on Biomimetic Coating Deposition

Materials Science Forum ◽

10.4028/www.scientific.net/msf.727-728.1622 ◽

2012 ◽

Vol 727-728 ◽

pp. 1622-1627

Author(s):

Roseli Marins Balestra ◽

Alexandre Antunes Ribeiro ◽

M.C. Andrade ◽

Luiz Carlos Pereira ◽

Marize Varella

Keyword(s):

Powder Metallurgy ◽

Calcium Phosphate ◽

Calcium Phosphates ◽

Titanium Implants ◽

Precipitation Method ◽

Phosphate Coatings ◽

Biomimetic Coating ◽

Simplified Solution ◽

Calcium Phosphate Coatings ◽

Titanium Substrates

Studies show that calcium phosphate coatings on titanium implants improve osseointegration at the implant-bone interface, due to the mineral biocompatibility. Titanium implants can be coated with calcium phosphates by a biomimetic precipitation method. This work studied a biomimetic method under a simplified solution with calcium and phosphorus ions. As substrates, commercially dense titanium sheet and macroporous titanium samples produced by powder metallurgy were used, both ASTM F67 grade 2. The substrates were submitted to chemical and heat treatment and then immersed in the solution for 10 days. Samples characterization was performed by Optical Microscopy (OM), Scanning Electron Microscopy/Energy Dispersive Spectroscopy (SEM/EDS), low angle X-ray Diffractometry (XRD) and Fourier Transform Infrared Spectroscopy (FTIR). Powder metallurgy successfully produced macroporous titanium substrates. Calcium phosphate coatings were deposited on both substrates, confirmed by FTIR bands. Such results indicated the potential of this methodology for calcium phosphate coatings on titanium substrates.

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