scholarly journals Approach to the Diagnostics of Atopic Dermatitis in Dogs in Conditions of Clinical Practice

2007 ◽  
Vol 76 (3) ◽  
pp. 461-468 ◽  
Author(s):  
S. Počta ◽  
M. Svoboda
Keyword(s):  
Atopic Dermatitis ◽  
Clinical Signs ◽  
The Other ◽  
Age Group ◽  
German Shepherd ◽  
Clinical Criteria ◽  
Allergy Test ◽  
Skin Allergy ◽  
The Difference ◽  
French Bulldog

The aim of this work was to elucidate the incidence of atopic dermatitis in dogs regarding their age, sex and individual breeds, verify the diagnostic criteria of the disease by Willemse and Prélaund and evaluate their sensitivity in the conditions of this country. In the group of 94 dogs, atopic dermatitis was diagnosed in the period from 1994 to 2005. The highest frequency among breeds was documented in Boxer (100%) and French Bulldog (84.6%), being significantly (p < 0.05) higher than in Shar-pei (41.7%) and Dalmatian (41.7%). The difference was even highly significant (p < 0.01) compared to Dachshund (2.7%), German Shepherd (6%), Cocker Spaniel (11.1%), and Poodle (3.3%). On the other hand, no significant differences were found between sexes. The commonly affected age group was 67 patients (71.2% cases) at the age between three and six years. The diagnosis was made using the clinical criteria by Willemse and Prélaund to verify the sensitivity of these criteria. It was found to be 72% by Willemse, 68% by Prélaund, and the difference was not statistically significant. In all 94 patients various stages of pruritus were detected. The most frequent clinical signs were facial or digital affecting 94.7% patients (89/91) and secondary pyoderma was found in 72.3% patients (68/94). Skin allergy test for specification of the diagnosis was performed in 73.4% cases (69/94).

Prevalence and features of canine atopic dermatitis in Hungary

2006 ◽  
Vol 54 (3) ◽  
pp. 353-366 ◽  
Author(s):  
Noémi Tarpataki ◽  
Kinga Pápa ◽  
J. Reiczigel ◽  
P. Vajdovich ◽  
K. Vörös
Keyword(s):  
Atopic Dermatitis ◽  
Age Of Onset ◽  
Skin Testing ◽  
Large City ◽  
Clinical Signs ◽  
House Dust Mites ◽  
Dust Mites ◽  
Dermatophagoides Farinae ◽  
Doberman Pinscher ◽  
French Bulldog

Medical records of 600 dogs diagnosed with atopic dermatitis were reviewed and evaluated with reference to history, geographical distribution, breed predilection, clinical signs and positive reactions to allergens as determined by intradermal skin testing (IDT) manufactured by Artuvetrin Laboratories**. In 66.6% of dogs, the age of onset of atopic dermatitis was between 4 months and 3 years. Dogs living in the garden suburb of Budapest were more sensitive to house dust mites, fleas and moulds, and dogs from the western part of Hungary were more sensitive to weeds than to other allergens (p < 0.01). Positive reactions were most common to Dermatophagoides farinae followed by human dander. The breed distribution found in the present study was consistent with that reported in the literature, except for the breeds Hungarian Vizsla, Pumi, French bulldog, Doberman Pinscher and Bobtail which were over-represented among atopic dogs compared to the breed distribution of the general dog population of a large city in Hungary. Breeds with verified adverse reaction to food were Cocker spaniels, French bulldogs, Bullmastiffs, Bull terriers, St. Bernards, Tervurens, West Highland White terriers and American Staffordshire terriers (p < 0.05). The clinical signs of atopic dermatitis and their occurrence are in accordance with the data described in the literature.

scholarly journals Bacterial vaginosis in Pregnant Women: A diagnostic approach

2016 ◽  
Vol 10 (1) ◽  
Author(s):  
Maleeha Aslam ◽  
Rubeena Hafeez ◽  
Shahbaz Aman ◽  
Anjum Azhar ◽  
Durre Shahwar Lone
Keyword(s):  
Bacterial Vaginosis ◽  
Pregnant Women ◽  
Vaginal Discharge ◽  
Clinical Signs ◽  
Accurate Diagnosis ◽  
The Other ◽  
Diagnostic Approach ◽  
Gardnerella Vaginalis ◽  
Common Symptom ◽  
Clinical Criteria

Objective: To determine the prevalence of Bacterial Vaginosis (BV) in pregnant women using a simple clinical diagnostic approach. Method: The clinical criteria developed by Amsel`s and colleagues were used as a reference standard for accurate diagnosis of Bacterial vaginosis (BV) infection. This is based on the presence of the following clinical signs 1) Homogeneous thin, white vaginal discharge 2) Presence of clue cells (greater than 20%). 3) Positive amine (whiff) test. 4) Vaginal pH > than 4.5. The presence of any three of the four clinical criteria was considered diagnostic for BV. Samples were collected from 75 pregnant females, irrespective of their gestational duration, presenting with vaginal discharge at the antenatal clinic of Jinnah Hospital, Lahore. Results: BV was diagnosed in 14 females giving an incidence of 18.7%. The, most common symptom was a thin white homogeneous vaginal discharge seen in 27(36%) women. The other diagnostic clinical signs observed were the presence of clue cells on wet mount 9(12%), positive `whiff` test 13(17.3%), and elevated pH>4.5 in 18(24%) women. Microscopic analysis of vaginal secretion revealed diminished polymorph epithelial ratio 19(25.3%) and loss of normal vaginal Lactobaclli 22(29.3%). The other associated findings were candidiasis seen in 16(21.3%) women, while Trichomonas infection in only one woman. These findings were confirmed on Gram staining. Gardnerella vaginalis 9(12%) and Gram variable organisms (Mobiluncus) 11(14.7%) were also identified by Gram smear of vaginal discharge. Conclusion: The clinical diagnosis of BV infection can be established by identifying three of Amsel`s four clinical criteria. In most cases it provides a rapid inexpensive and accurate diagnosis. Strategies should be planned to screen and treat women with BV so as to prevent adverse Obstetric outcome associated with it.

Incidence of Canine Digestive System Tumours in Baghdad Province

2019 ◽  
Vol 43 (2) ◽  
pp. 67-76
Author(s):  
Huda Hameed Kadhim Alabbody
Keyword(s):  
Digestive System ◽  
Carcinoid Tumour ◽  
Clinical Signs ◽  
The Other ◽  
Bloody Stool ◽  
Gi Tract ◽  
German Shepherd ◽  
Teaching Animal ◽  
Benign Tumours ◽  
Vegetables And Fruits

Tumours in pets occur naturally are as common in dogs as they are in humans. Tumours of the alimentary system have been reported in animals, although less frequently. Food patterns and specific diet components could have a big role in such tumour occurrence. Therefore, the aim of this study was to investigate the clinical signs and inspect the neoplasm lesions of the gastrointestinal (GI) tract grossly and histopathologically in dogs in Baghdad, Iraq, and to see whether pet diets had any tumourigenic effect. Throughout two years sixteen dogswere referred to Teaching Animal Hospital and private clinics at Baghdad city had masses in (GI) tract. Males and the large sizes breeds were more likely to be affected with GI tumours. Half of the cases aged 5-10 years and belonged to German Shepherd, while the other half involved the other breeds (i.e. Belgian Malinois, Labrador, Pointer GSP and Terrier) equally. Biopsies were taken from the tumour tissues for histological examination. Clinically, the animals presented general signs of digestive system abnormalities like difficulty defecating, bloody stool, lethargy and weight loss. Grossly, the tumours varied in their sizes from <3 cm to >5 cm in diameter, and the most frequent site of occurrence (10 out of 16 cases) was in the large intestine. Histologically, the most tumours reported were malignant, and included adenocarcinomas (6/16) followed by leiomyosarcoma (4/16), and 2/16 belonged to carcinoid tumour. However, lipoma and viral papilloma (4/16)   were also registered as the benign tumours. Inconclusion,tumours of canine digestive system do exist but rare. The healthy nutrition of dog may be prevent this type of tumour when dog consume  enough amount of raw meat, little of artificial food like kibble with small of some vegetables and fruits. Additionally, the information gained from dogs could be used to suspect and test the effect on humans as they have strong pathophysiology similarities

scholarly journals Efficacy of hydrolyzed soy dog food and homemade food with original protein in the control of food-induced atopic dermatitis in dogs

2018 ◽  
Vol 38 (7) ◽  
pp. 1389-1393
Author(s):  
Graziele Vandresen ◽  
Marconi R. de Farias
Keyword(s):  
Atopic Dermatitis ◽  
Clinical Signs ◽  
Food Group ◽  
The Other ◽  
Complete Control ◽  
Protein Sources ◽  
Dog Food ◽  
Significant Difference ◽  
Chronic Pruritus ◽  
Lesion Index

ABSTRACT: Trophoallergens are specific components of food or its ingredients, able to precipitate the atopic eczema at 19.6% to 30% of the dogs with atopic dermatitis (AD). This study evaluated the efficacy of hydrolyzed soy dog food and homemade food with unusual protein in the control of chronic pruritus in dogs with AD. For this, twenty-eight dogs with AD were selected. AD diagnosis was based on Favrot’s criteria. The animals were separated in two groups; one group consumed hydrolyzed soy dog food while the other group consumed homemade food with protein sources and original carbohydrates. They were evaluated every two weeks by the Rybnicek and CADLI scale over 60 days. Animals in the group that consumed hydrolyzed soy dog food presented a reduced score of pruritus (Rybnicek scale) on days +15, +30, +45 and +60 (P<0.01) compared to day 0. While the dogs in the homemade food group have not presented a significant difference (P>0.05) in 60 days of treatment. When evaluated by the Canine Atopic Dermatitis Lesion Index (CADLI), dogs treated with soy hydrolyzed dog food had a partial improvement on days +45 (P<0.05) and +60 (P<0.01) compared to day 0, while the dogs in the second group did not show improvements (P>0.05) in 60 days of treatment. In conclusion, soy hydrolyzed dog food has proved effective to partially control clinical signs of food-induced atopic dermatitis; however, it is not effective for the complete control of the disease.

scholarly journals Canine atopic dermatitis in the Middle East: clinical signs, signalment and common allergens

2012 ◽  
Vol 57 (No. 8) ◽  
pp. 410-419 ◽  
Author(s):  
G. Zur ◽  
I. Skorinsky ◽  
T. Bdolah-Abram
Keyword(s):  
Atopic Dermatitis ◽  
Middle Eastern ◽  
Disease Onset ◽  
Clinical Signs ◽  
Onset Time ◽  
Skin Lesions ◽  
The Body ◽  
German Shepherd ◽  
Canine Atopic Dermatitis ◽  
German Shepherd Dog

&nbsp; The aim of the study was to examine for the first time the various aspects of canine atopic dermatitis (CAD) presenting in a Middle Eastern country. Medical records of 164 dogs diagnosed with CAD were evaluated. Associations between signalment, lifestyle, clinical signs and allergens were evaluated statistically. Labrador Retriever, German Shepherd dog, Boxer, French Bulldog, Golden Retriever and Shar-Pei breeds were presented more frequently than the regular hospital population (P &lt; 0.0001), and had an earlier disease onset time (P &lt; 0.01). In 22 dogs (13%) signs of CAD were noticed at less than six months of age. Most dogs (75%) lived indoors. Most dogs (83%) had lesions on the ventral part of the body and 68% had foot lesions. After excluding flea allergy dermatitis by implementing strict flea control, 60% of the dogs presented with dorsal distribution of skin lesions. Dogs with ventral lesions were younger when clinical signs first appeared (P &lt; 0.05). Most of the dogs were allergic to dust and/or dust mites (75.6%), with weeds and trees as the next most common allergens. CAD is similar worldwide, but geographic differences may be attributable to genetic pools and allergen loading. This study also shows that early onset of clinical signs, especially in breeds predisposed to CAD and with a dorsal distribution of skin lesions, should not rule out the diagnosis of CAD. &nbsp;

scholarly journals Anti-beta 2 glycoprotein I IgA in the SLICC classification criteria dataset

Lupus ◽  
2021 ◽  
pp. 096120332110142
Author(s):  
Marwa Elkhalifa ◽  
Ana-Maria Orbai ◽  
Laurence S Magder ◽  
Michelle Petri ◽  
Graciela S Alarcón ◽  
...  
Keyword(s):  
Rheumatic Diseases ◽  
African Descent ◽  
Clinical Manifestations ◽  
Classification Criteria ◽  
The Other ◽  
Clinical Criteria ◽  
American College Of Rheumatology ◽  
Glycoprotein I ◽  
Beta 2 ◽  
The Difference

Objective Anti-beta 2 glycoprotein I IgA is a common isotype of anti-beta 2 glycoprotein I in SLE. Anti-beta 2 glycoprotein I was not included in the American College of Rheumatology (ACR) SLE classification criteria, but was included in the Systemic Lupus International Collaborating Clinics (SLICC) criteria. We aimed to evaluate the prevalence of anti-beta 2-glycoprotein I IgA in SLE versus other rheumatic diseases. In addition, we examined the association between anti-beta 2 glycoprotein I IgA and disease manifestations in SLE. Methods The dataset consisted of 1384 patients, 657 with a consensus physician diagnosis of SLE and 727 controls with other rheumatic diseases. Anti-beta 2 glycoprotein I isotypes were measured by ELISA. Patients with a consensus diagnosis of SLE were compared to controls with respect to presence of anti-beta 2 glycoprotein I. Among patients with SLE, we assessed the association between anti-beta 2 glycoprotein I IgA and clinical manifestations. Results The prevalence of anti-beta 2 glycoprotein I IgA was 14% in SLE patients and 7% in rheumatic disease controls (odds ratio, OR 2.3, 95% CI: 1.6, 3.3). It was more common in SLE patients who were younger patients and of African descent (p = 0.019). Eleven percent of SLE patients had anti-beta 2 glycoprotein I IgA alone (no anti-beta 2 glycoprotein I IgG or IgM). There was a significant association between anti-beta 2 glycoprotein I IgA and anti-dsDNA (p = 0.001) and the other antiphospholipid antibodies (p = 0.0004). There was no significant correlation of anti-beta 2 glycoprotein I IgA with any of the other ACR or SLICC clinical criteria for SLE. Those with anti-beta 2 glycoprotein I IgA tended to have a history of thrombosis (12% vs 6%, p = 0.071), but the difference was not statistically significant. Conclusion We found the anti-beta 2 glycoprotein I IgA isotype to be more common in patients with SLE and in particular, with African descent. It could occur alone without other isotypes.

scholarly journals The Impact of Pandemics on Workforce Joblessness in Central Europe in pre-Covid Era and during Pandemic

2021 ◽  
pp. 1-6
Author(s):  
Michal Beno
Keyword(s):  
Czech Republic ◽  
The Other ◽  
Age Group ◽  
The Czech Republic ◽  
Significant Difference ◽  
The Difference ◽  
Gender Unemployment Gap ◽  
One Year ◽  
The Impact ◽  
Oecd Data

Unemployment affects individuals socially, personally, and economically. The impact of being jobless can be long-lasting. Five different generations participate in the workplace today. As countries throughout the world went into lockdown to combat the spread of Covid-19, unemployment numbers rose rapidly. This study aimed to examine the effects of unemployment in three-generation groups in V4 and Austria in the pre-Covid-19 era and during Covid-19. Descriptive statistics were used to present the collected data. OECD data were used for the analysis. Based on the data collected, unemployment decreases with age. The group aged 15-24 shows significantly higher unemployment than the other two groups. A gender difference in unemployment was confirmed only in the Czech Republic and Slovakia. Unemployment has increased during the Covid-19 pandemic. The unemployment gap for females before and during Covid-19 was not confirmed. The T-Test confirmed the difference in unemployment before and during the crisis in the age categories 15-24 and 25-54. In Hungary, Poland, and Slovakia, the number of people with a duration of employment of up to one year differs in all age categories. In the Czech Republic, there is a significant difference only between the youngest group and the other two. In all countries, the largest number of people with the employment of up to one year is in the age group 25-54. In none of the examined countries was a gender unemployment gap proved before Covid-19.

Influence of Age Breed and Sex on Incidence of Renal Disorders in Dogs

2021 ◽  
Author(s):  
A. Ahmad ◽  
D. Swarup ◽  
S. Dey
Keyword(s):  
Essential Role ◽  
Kidney Diseases ◽  
Age Groups ◽  
Clinical Signs ◽  
Renal Diseases ◽  
Age Group ◽  
German Shepherd ◽  
Renal Disorder ◽  
Renal Disorders ◽  
Biochemical Alterations

Background: Kidneys play an essential role in health, disease, and growth. Renal disorders are among the most common ailments of dogs and contribute substantially to canine mortality, particularly in older dogs. Fewer published reports are documenting the prevalence of renal diseases in dogs in India. The current study was undertaken to find out the incidence of renal disorder in dogs based on their age and breed and sex. Methods: The assessment of the incidence of renal disorders in dogs was done in the clinical cases reported at Referral Veterinary Polyclinic, IVRI during the period i.e. February 2010 to January 2011. The total numbers of 880 cases of dogs suffering from different ailments were reported during this period, out of which 63 dogs were suspected and screened for renal disorders based on clinical signs, ultrasonographic findings, serum and urinary biochemical alterations and urine analysis.Result: The overall incidence of renal disorders was 7.15% recorded according to the age of dogs. No renal disorders were detected in the dogs less than 6 years of age. 3.26% dogs of 6-8 year age group were confirmed for kidney diseases. Whereas 9.30% and 13.94% dogs in the age groups of 8 -10 year and ≥ 10 years, respectively had renal disorders. The breed wise renal disorders in dogs showed the highest incidence in Labrador dogs followed by Bulldogs, Dalmatian, Great Dane and Rottweiler, Doberman, German Shepherd and Pomeranian. Interestingly lowest incidence was recorded in the mixed or non-descript breed. Out of 63 dogs, 36 male (57%) and 27 female (43%) dogs were confirmed for renal disorders indicating a higher prevalence of renal diseases in males than females.

scholarly journals Autochthonous Angiostrongylus vasorum in Finland

2019 ◽  
Vol 6 (1) ◽  
pp. e000314 ◽  
Author(s):  
Valentina Tiškina ◽  
Eeva-Liisa Lindqvist ◽  
Anna-Clara Blomqvist ◽  
Merle Orav ◽  
Christen Rune Stensvold ◽  
...  
Keyword(s):  
Direct Detection ◽  
Clinical Signs ◽  
Old French ◽  
Domestic Dogs ◽  
The Other ◽  
Angiostrongylus Vasorum ◽  
Antigen Test ◽  
Online Questionnaire ◽  
History Of ◽  
French Bulldog

Angiostrongylus vasorum has spread farther north in Europe. In this study, two autochthonous findings from dogs from Finland are described: in February 2014, the infection was diagnosed in a 10-month-old labrador retriever, and in February 2017, in a three-year-old French bulldog. These diagnoses were based on direct detection of the larvae from faeces of the dogs. The dogs had no history of travel to or import from abroad; the first lived in Southern Finland and the other in Western Finland, about 150 km apart. The dogs had no clinical signs attributable to angiostrongylosis. An online questionnaire was used to survey the extent to which veterinarians in Finland have self-reportedly observed canine A vasorum infections. A total of 38 veterinarians authorised to work in Finland answered the questionnaire in December 2017, and 9 (24%) of them reported having seen one or more dogs with A vasorum infection in Finland. The results suggest that at least five individual dogs with A vasorum infection would have been seen in Finland, three of which had an apparently autochthonous infection. While the geographical distribution of A vasorum in Finland remains largely unknown, findings have started to appear from domestic dogs. It remains possible that some veterinarians could have misdiagnosed, for example, Crenosoma vulpis larvae as those of A vasorum, and the findings without confirmation using antigen test could be due to coprophagy and passage of ingested larvae; however, this does not change the main conclusion that can be made: A vasorum is already multifocally present in Finland. Increasing awareness about A vasorum is important in areas where it is emerging and spreading.

Enhancement of ADP-induced Platelet Aggregation by Adrenaline in Vivo and Its Prevention

1973 ◽  
Vol 29 (02) ◽  
pp. 490-498 ◽  
Author(s):  
Hiroh Yamazaki ◽  
Itsuro Kobayashi ◽  
Tadahiro Sano ◽  
Takio Shimamoto
Keyword(s):  
Platelet Count ◽  
Platelet Aggregation ◽  
Platelet Rich Plasma ◽  
The Other ◽  
Endothelial Surface ◽  
Important Interaction ◽  
Blood Coagulability ◽  
The Difference

SummaryThe authors previously reported a transient decrease in adhesive platelet count and an enhancement of blood coagulability after administration of a small amount of adrenaline (0.1-1 µg per Kg, i. v.) in man and rabbit. In such circumstances, the sensitivity of platelets to aggregation induced by ADP was studied by an optical density method. Five minutes after i. v. injection of 1 µg per Kg of adrenaline in 10 rabbits, intensity of platelet aggregation increased to 115.1 ± 4.9% (mean ± S. E.) by 10∼5 molar, 121.8 ± 7.8% by 3 × 10-6 molar and 129.4 ± 12.8% of the value before the injection by 10”6 molar ADP. The difference was statistically significant (P<0.01-0.05). The above change was not observed in each group of rabbits injected with saline, 1 µg per Kg of 1-noradrenaline or 0.1 and 10 µg per Kg of adrenaline. Also, it was prevented by oral administration of 10 mg per Kg of phenoxybenzamine or propranolol or aspirin or pyridinolcarbamate 3 hours before the challenge. On the other hand, the enhancement of ADP-induced platelet aggregation was not observed in vitro, when 10-5 or 3 × 10-6 molar and 129.4 ± 12.8% of the value before 10∼6 molar ADP was added to citrated platelet rich plasma (CPRP) of rabbit after incubation at 37°C for 30 second with 0.01, 0.1, 1, 10 or 100 µg per ml of adrenaline or noradrenaline. These results suggest an important interaction between endothelial surface and platelets in connection with the enhancement of ADP-induced platelet aggregation by adrenaline in vivo.

Sign in / Sign up

Export Citation Format

Share Document